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You searched for: Journal Biomaterials Remove constraint Journal: Biomaterials Subject calcitonin receptors Remove constraint Subject: calcitonin receptors Subject term calcitonin receptors Remove constraint Subject term: calcitonin receptors
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1. The role of the ERK1/2 pathway as an alternative to the aging-diminished cyclic AMP pathway in calcitonin-mediated chondrogenesis in human nucleus pulposus

Author:
Wei-Hong Chen; Rong Zeng; Wen-Cheng Lo; Szu-Yu Tina Chen; Tung-Yuan Lai; David F. Williams; Win-Ping Deng
Source:
Biomaterials 2012 v.33 no.33 pp. 8256-8264
ISSN:
0142-9612
Subject:
calcitonin; calcitonin receptors; chondrogenesis; cyclic AMP; humans; phenotype; signal transduction; therapeutics
Abstract:
... Human disc degeneration initiated by aging in the central nucleus pulposus (hNP) is an irreversible process and the recovery has become seriously emerging. In this study, the related mechanisms of calcitonin on the regeneration of hNP and the effects of calcitonin on the age-related alterations were examined. The harvested hNP population was designated as YhNP (from young donor, age <50) and OhNP ...
DOI:
10.1016/j.biomaterials.2012.06.088

2. Direct and indirect effects of functionalised fluorescence-labelled nanoparticles on human osteoclast formation and activity

Author:
Andrea Tautzenberger; Ludwika Kreja; Anke Zeller; Steffen Lorenz; Hubert Schrezenmeier; Volker Mailänder; Katharina Landfester; Anita Ignatius
Source:
Biomaterials 2011 v.32 no.6 pp. 1706-1714
ISSN:
0142-9612
Subject:
acid phosphatase; actin; calcitonin receptors; calcium phosphates; cathepsin K; confocal laser scanning microscopy; drugs; fluorescence microscopy; genes; humans; inflammation; interleukin-1beta; interleukin-6; nanoparticles; osteoblasts; osteoclasts; proton pump; resorption; secretion; stem cells; transmission electron microscopy; viability
Abstract:
... Recently, it was demonstrated that phosphonate-functionalised nanoparticles were successfully taken up by mesenchymal stem cells without influencing their viability and differentiation capacity, suggesting that they may provide a promising basis for the development of nanoparticles for drug delivery or cell labelling. The present study aimed to investigate the effects of these nanoparticles on ost ...
DOI:
10.1016/j.biomaterials.2010.10.053