Journal: Chinese journal of natural medicines / Subject: cell lines and antineoplastic activity / Subject term: antineoplastic activity / Text Availability: Citation in PubAg

Author:: Se-Eun LEE; Zhanna OKHLOPKOVA; Chiyeon LIM; Suin CHO
Source:: Chinese journal of natural medicines 2020 v.18 no.10 pp. 793-800
ISSN:: 1875-5364
Subject:: B-cell lymphoma; Dracocephalum; Russia; Western blotting; adenosine diphosphate; antineoplastic activity; antioxidant activity; apoptosis; caspase-8; cell cycle checkpoints; cell lines; cell proliferation; drug therapy; ethyl acetate; flavonoids; humans; leaves; medicinal plants; neoplasm cells; nomadic people; prostatic neoplasms; reactive oxygen species; research; ribose; superoxide dismutase
Abstract:: ... Dracocephalum palmatum Stephan is a medicinal plant traditionally used by nomadic people in Eastern Russia; however, research on this plant is currently limited. Recently, although studies have been conducted on the constituents of this plant and their antioxidant effects, data on its various pharmacological activities are still lacking. Thus, this study examined the anticancer potential of the dr ...
DOI:: 10.1016/S1875-5364(20)60019-X
: https://doi.org/10.1016/S1875-5364(20)60019-X

Author:: Si-Yuan JING; Zi-Dan WU; Tie-Hua ZHANG; Jie ZHANG; Zheng-Yi WEI
Source:: Chinese journal of natural medicines 2020 v.18 no.7 pp. 483-490
ISSN:: 1875-5364
Subject:: antineoplastic activity; apoptosis; cell cycle checkpoints; cell lines; epidermal growth factor; humans; lung neoplasms; molecular dynamics; neoplasm cells; phosphorylation; pro-apoptotic proteins; protein kinases; signal transduction; transcription factors; tyrosine
Abstract:: ... Cucurbitacin E (CuE) is previously reported to exhibit antitumor effect by several means. In this study, CuE acted as a tyrosine kinase inhibitor interfering with the epidermal growth factor receptor/mitogen-activated protein kinase (EGFR/MAPK) signaling pathway and subsequently induced apoptosis and cell cycle arrest in non-small-cell lung cancer (NSCLC) cell line A549. The apoptosis regulators, ...
DOI:: 10.1016/S1875-5364(20)30058-3
: https://doi.org/10.1016/S1875-5364(20)30058-3

Author:: Zheng LI; Qian-Qian CHEN; Christopher Wai Kei LAM; Jian-Ru GUO; Wei-Jia ZHANG; Cai-Yun WANG; Vincent Kam Wai WONG; Mei-Cun YAO; Wei ZHANG
Source:: Chinese journal of natural medicines 2019 v.17 no.8 pp. 608-615
ISSN:: 1875-5364
Subject:: DNA replication; Oriental traditional medicine; adenocarcinoma; antineoplastic activity; cell cycle checkpoints; cell lines; cytotoxicity; epithelial cells; humans; hydroxyurea; interphase; liquid chromatography; lungs; mass spectrometry; metabolism; metabolomics; nucleosides; resveratrol
Abstract:: ... In an effort to understand the molecular events contributing to the cytotoxicity activity of resveratrol (RSV), we investigated its effects on human lung adenocarcinoma epithelial cell line A549 at different concentrations. Cellular nucleoside metabolic profiling was determined by an established liquid chromatography-mass spectrometry method in A549 cells. RSV resulted in significant decreases and ...
DOI:: 10.1016/S1875-5364(19)30063-9
: https://doi.org/10.1016/S1875-5364(19)30063-9

Author:: Peng-Cheng LIN; Lin-Lin JI; Xiang-Jian ZHONG; Jin-Jie LI; Xin WANG; Xiao-Ya SHANG; Sheng LIN
Source:: Chinese journal of natural medicines 2019 v.17 no.1 pp. 22-26
ISSN:: 1875-5364
Subject:: Cirsium arvense; Oriental traditional medicine; animal ovaries; antineoplastic activity; cell lines; chemical structure; colorectal neoplasms; cytotoxicity; food plants; humans; inhibitory concentration 50; ovarian neoplasms; secretion; spectral analysis; triterpenoids; tumor necrosis factor-alpha
Abstract:: ... Guided by TNF-α secretion inhibitory activity assay, four taraxastane-type triterpenoids, including two new ones, 22-oxo-20-taraxasten-3β, 30-diol (1) and 22α-hydroxy-20-taraxasten-30β, 30-triol (2), have been obtained from an active fraction of the petroleum ether-soluble extract of the the medicinal and edible plant Cirsium setosum. Their structures were elucidated by spectroscopic data and CD d ...
DOI:: 10.1016/S1875-5364(19)30005-6
: https://doi.org/10.1016/S1875-5364(19)30005-6

Author:: Ashwini Anjana; K.F.H Nazeer Ahamed; V. Ravichandiran; M. Sumithra; Jayaraman Anbu
Source:: Chinese journal of natural medicines 2014 v.12 no.2 pp. 114-120
ISSN:: 1875-5364
Subject:: Oriental traditional medicine; Sargassum wightii; antineoplastic activity; antioxidant activity; body weight; cell lines; cell proliferation; flavonoids; hematologic tests; longevity; lymphoma; mice; neoplasm cells
Abstract:: ... Sargassum wightii Greville is a marine brown alga belonging to the Sargassaceae family which has about 200 species. The ethanolic extract of the whole dry plant powder contained numerous phytoconstituents, including flavonoids. The study was focused on the anticancer activity of Sargassum wightii in mice.The ethanolic extract of Sargassum wightii (EESW) at two dose levels was used to examine the a ...
DOI:: 10.1016/S1875-5364(14)60018-2
: https://doi.org/10.1016/S1875-5364(14)60018-2

Author:: Min-Yu LIU; Lin XIAO; Geng-Hui CHEN; Yong-Xiang WANG; Wei-Xia XIONG; Fei LI; Ying LIU; Xiao-Ling HUANG; Yi-Fang DENG; Zhen ZHANG; Hai-Yan SUN; Quan-Hai LIU; Ming YIN
Source:: Chinese journal of natural medicines 2014 v.12 no.10 pp. 768-776
ISSN:: 1875-5364
Subject:: Oriental traditional medicine; Xenorhabdus; allografting; animal models; antineoplastic activity; apoptosis; body weight; cell lines; cyclophosphamide; fluorouracil; granulocyte colony-stimulating factor; hepatoma; humans; inhibitory concentration 50; lung neoplasms; metabolites; mice; neoplasm cells; neutropenia; neutrophils; sarcoma
Abstract:: ... JS-38 (mitothiolore), a synthetic version of a metabolite isolated from Xenorhabdus sp., was evaluated for its anti-tumor and white blood cell (WBC) elevating activities.These anti-proliferative activities were assessed in vitro using a panel of ten cell lines. The anti-tumor activities were tested in vivo using B16 allograft mouse models and xenograft models of A549 human lung carcinoma and QGY h ...
DOI:: 10.1016/S1875-5364(14)60117-5
: https://doi.org/10.1016/S1875-5364(14)60117-5

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