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adverse effects; blood lipids; body mass index; brain; carotid arteries; children; diastolic blood pressure; encephalopathy; fasting; glucose; high density lipoprotein cholesterol; hospitals; hyperlipidemia; ketogenic diet; ketones; low density lipoprotein cholesterol; movement disorders; nutritional intervention; patients; risk factors; statistical analysis; triacylglycerols; Germany
Abstract:
... Glut1 Deficiency (Glut1D) is caused by impaired glucose transport into brain. The resulting epileptic encephalopathy and movement disorders can be treated effectively by high-fat carbohydrate-restricted ketogenic diet therapies (KDT) mimicking fasting and providing ketones as an alternative cerebral fuel. Recently 6–24 months follow-ups of epileptic patients reported elevated blood lipids and inti ...
... The past century had witnessed vast advances in biomedical research, particularly in the fields of genomics and proteomics, yet the translation of these discoveries into clinical practice has been hindered by gaps in mechanistic understanding of variability governing disease susceptibility and pathogenesis. Among the greatest challenges are the dynamic nature of the proteome and the imperfect meth ...
... Cancer cachexia is a multifactorial syndrome characterised by loss of skeletal muscle that cannot be fully reversed by conventional nutritional support. Uncertainty continues as to its precise mediators and mechanisms. The pathophysiology is characterised by a variable combination of reduced food intake and abnormal metabolism. Recent evidence has suggested that there may be a genetic component to ...
adverse effects; bags; emulsions; energy; enteral feeding; equations; fatty liver; glutamine; hyperglycemia; inflammation; lipids; malnutrition; mortality; overfeeding; patients; sepsis (infection); total parenteral nutrition; Australia; Belgium; Israel; United States
Abstract:
... Fifty years after the clinical introduction of total parenteral nutrition (TPN) the Arvid Wretlind lecture is an opportunity to critically analyse the evolution and changes that have marked its development and clinical use. The standard crystalline amino acid solutions, while devoid of side effects, remain incomplete regarding their composition (e.g. glutamine). Lipid emulsions have evolved tremen ...
... COPD is a chronic disease of the lungs, but heterogeneous with respect to clinical manifestations and disease progression. This has consequences for health risk assessment, stratification and management. Heterogeneity can be driven by pulmonary events but also by systemic consequences (e.g. cachexia and muscle weakness) and co-morbidity (e.g. osteoporosis, diabetes and cardiovascular disease). Thi ...
... The aim of the present lecture is to review the changes in perioperative nutritional policy throughout years. Many advances on both knowledge and clinical practice occurred with time, particularly on preoperative patient assessment and preparation, modulation of surgical stress, identification of the gut as regulator of postoperative inflammatory response, and perioperative fasting policy. Improve ...
... Alterations in amino acid protein metabolism are a key feature of the cancer cachexia syndrome. These changes –induced by both hormonal changes (that affect insulin sensitivity) and inflammatory mediators– are present in skeletal muscle influencing both, amino acid uptake and protein synthesis. In addition, skeletal muscle protein turnover is characterized by an exacerbated rate of protein degrada ...
... The gut has a major influence on the course of the human stress response in critical illness for several reasons; the quantity of its immune tissue, the extent of interface with the external environment, the expanse of the microbiome, and its access to the systemic circulation. In critical illness, it is not uncommon to lose mucosal barrier function, which exposes the host to the downside effects ...
... The perioperative severe changes in the nutritional and metabolic homeostasis are, by some means, proportional to the extent of tissue injury and magnitude of operative trauma. An adequate qualitative and quantitative replacement of nutritional substrates are of utmost importance to facilitate proper tissue healing and recovery and maintenance of organ function after surgery.The present manuscript ...
... Owing to the “obesity-pandemic”, an increasing number of individuals are in need of treatment for obesity and obesity-related disorders. For patients with severe disease, results with conventional treatment modalities such as diet regimens, physical activity, and pharmacologic agents most often lack satisfactory efficacy and/or sustainability. In contrast, bariatric surgery has been demonstrated t ...
Carlijn T.I. de Betue; Xiomara C. Garcia Casal; Dick A. van Waardenburg; Stephen M. Schexnayder; Koen F.M. Joosten; Nicolaas E.P. Deutz; Marielle P.K.J. Engelen
... The reference method to study protein and arginine metabolism in critically ill children is measuring plasma amino acid appearances with stable isotopes during a short (4–8 h) time period and extrapolate results to 24-h. However, 24-h measurements may be variable due to critical illness related factors and a circadian rhythm could be present. Since only short duration stable isotope studies in cri ...
... BACKGROUND & AIMS: To describe actual data on intake, sources, age and time trends of urinary sodium excretion and to analyze the potential association between urinary sodium excretion and hydration status respective beverage consumption in a sample of healthy German children and adolescents. METHODS: Data of 1575 24 h-urine samples and weighed dietary records of 499 children (249 boys) aged 4–18 ...
Ilse I.M. Tromp; Oscar H. Franco; Edith H. van den Hooven; Annemieke C. Heijboer; Vincent W.V. Jaddoe; Liesbeth Duijts; Johan C. de Jongste; Henriëtte A. Moll; Jessica C. Kiefte-de Jong
... A role of vitamin D in the development of respiratory and allergic disease in children remains unclear. It may be likely that vitamin D has an effect on airway inflammation, but only few studies examined the effect in children. We aimed to examine whether serum 25-hydroxyvitamin D (25(OH) vitamin D) concentrations are associated with the fraction of exhaled nitric oxide (FeNO), airway interrupter ...
... A growing number of studies have shown that vitamin D are related to the risk of stroke, however, the dose–response association between vitamin D and the risk of stroke is still unclear. Accordingly, we conducted a dose–response meta-analysis to evaluate the relationships between 25-hydroxyvitamin D [25(OH)D] level, vitamin D intake, and the risk of stroke by summarizing cohort studies.PubMed, Emb ...
X-ray absorption spectroscopy; bioelectrical impedance; body fat; densitometry; dual-energy X-ray absorptiometry; lean body mass; regression analysis; scanners
Abstract:
... Body composition assessment via 3-dimensional optical (3DO) scanning has emerged as a rapid and simple evaluation method. The aim of this study was to establish the precision of body composition estimates from four commercially available 3DO scanners and evaluate their validity as compared to a reference 4-component (4C) model.The body composition of 171 participants was assessed using four commer ...
adults; anxiety; binging; body mass index; bulimia nervosa; inventories; patients; psychotherapy; questionnaires; surveys; tube feeding
Abstract:
... To study the 1-yr follow-up of 118 bulimia nervosa (BN) patients after a 3-month at-home tube feeding (TF) in a prospective study.At-home TF lasted 3 months, including one month of exclusive TF (no food). All patients fulfilled 4 questionnaires (score of binge/purging episodes (BP), eating disorder inventory, anxiety, depression), before, at the 3-month TF point, and 6 and 12 months latter.The sco ...
alcohols; cohort studies; comorbidity; drug therapy; eating habits; elderly; females; food frequency questionnaires; food groups; lifestyle; longitudinal studies; models; noodles; pickles; principal component analysis; risk; sugars; Asia
Abstract:
... The association between dietary patterns and frailty is less investigated in Asia. We aimed to investigate the prospective associations between dietary patterns and frailty index (FI) in community-dwelling Japanese older adults aged 60 years or older.A 3-year cohort collected the data on sociodemographic information, lifestyle behaviors, comorbidities, medication history, depression status, nutrit ...
adolescents; body mass index; females; lifestyle; overweight; surveys
Abstract:
... We present the 7-year follow-up analysis in overweight children and adolescents, who had participated originally in a randomized control trial of a lifestyle intervention. We compared them to an untreated population-based control group to demonstrate the effectiveness of the intervention.Degree of overweight (BMI-SDS) was determined in 32 overweight children (mean age 11.5 ± 1.5yrs, 65.6% females, ...
alleles; analysis of covariance; cholesterol; cross-sectional studies; food intake; genotype; high density lipoprotein; hyperlipidemia; lipid composition; low density lipoprotein; noninsulin-dependent diabetes mellitus; patients; saturated fatty acids; triacylglycerols
Abstract:
... Several studies have suggested that APOA II-265T/C polymorphism affect lipid profile. The aim of this study was to investigate the effect of −265T/C APOA II polymorphism and saturated fatty acids (SFA) intake interaction on lipid profile in diabetic population who are at risk for lipid disorders.In this cross sectional study, 697 type 2 diabetic patients participated. Food consumption data were co ...
... Atherosclerosis is characterized by an inflammatory disease linked to excessive lipid accumulation in the artery wall. The Notch signalling pathway has been shown to play a key regulatory role in the regulation of inflammation. Recently, in vitro and pre-clinical studies have shown that apolipoprotein A–I binding protein (AIBP) regulates cholesterol metabolism (SREBP) and NOTCH signalling (haemato ...
adults; alleles; apolipoprotein A-I; apolipoprotein B; apolipoprotein E; body fat; body mass index; cardiovascular diseases; cross-sectional studies; diastolic blood pressure; food intake; genotype; genotyping; hyperlipidemia; lifestyle; lipid composition; men; obesity; questionnaires; regression analysis; risk; systolic blood pressure; waist circumference; women
Abstract:
... Normal-Weight Obesity Syndrome has been characterized by a normal body mass index and high percentage of body fat. It is associated with an increased risk of cardiovascular disease development. This study aimed to evaluate whether apolipoprotein E (APOE) genotypes and food consumption are related to the lipid profiles of adults with Normal-Weight Obesity Syndrome.Analytical cross-sectional study, ...
clinical nutrition; dietetics; energy intake; enteral feeding; malnutrition; metabolism; muscles; patients; statistics; subcutaneous fat; weight loss; women
Abstract:
... The aim of this study was to assess the prevalence of malnutrition by applying the ASPEN/AND definition and the ESPEN consensus definition in a postacute-care population, and secondly, to determine the metrological properties of the set of six clinical characteristics that constitute the ASPEN/AND basic diagnosis, compared to the ESPEN consensus, based mostly on objective anthropometric measuremen ...
Dana Serfaty; Michal Rein; Dan Schwarzfuchs; Ilan Shelef; Yftach Gepner; Nitzan Bril; Noa Cohen; Elad Shemesh; Benjamin Sarusi; Julia Kovsan; Shira Kenigsbuch; Yoash Chassidim; Rachel Golan; Shula Witkow; Yaakov Henkin; Meir J. Stampfer; Assaf Rudich; Iris Shai
abdominal fat; accelerometry; body mass index; exercise; gender; heat production; magnetic resonance imaging; men; metabolism; models; multivariate analysis; resting energy expenditure; women
Abstract:
... We aimed to assess the association between the distinct abdominal sub-depots and resting energy expenditure (REE).We performed magnetic resonance imaging (MRI) to quantify abdominal visceral-adipose-tissue (VAT), deep-subcutaneous-adipose-tissue (deep-SAT), and superficial-subcutaneous-adipose-tissue (superficial-SAT). We measured REE by indirect-calorimetry. Non-exercise activity thermogenesis (N ...
... BACKGROUND & AIMS: Some home parenteral nutrition (HPN) patients develop catheter related bloodstream infections (CRBSI) despite using an anti-microbial catheter lock solution taurolidine. The aim of this study was to assess whether long-term use of taurolidine leads to selective growth of microorganisms with increased taurolidine minimum inhibitory concentrations (MICs). METHODS: Bloodstream infe ...
acute effects; ammonia; catheters; digestibility; energy metabolism; essential amino acids; gelatin; glucose; intestines; limiting amino acids; liver; protein intake; protein synthesis; swine; tryptophan; urea; whey; whey protein
Abstract:
... BACKGROUND & AIMS: Gut health relates to a diet with a high digestibility and quality. Limited data are available on the acute effects of low quality foods on gut metabolism and the consequences for liver metabolism. METHODS: A meal with the low quality protein gelatin (tryptophan deficient and low amount of essential amino acids) was compared to a meal with the high quality protein Whey and a try ...
calorimetry; carbon dioxide; children; data collection; equations; monitoring; nutrient intake; optimal nutrition; patients; prediction; respiratory quotient; resting energy expenditure
Abstract:
... Accurate assessment of resting energy expenditure (REE) and metabolic state is essential to optimize nutrient intake in critically ill patients. We aimed to examine the accuracy of a simplified equation for predicting REE using carbon dioxide elimination (VCO2) values.We conducted a two-center study of metabolic data from mechanically ventilated children less than 18 years of age. Mean respiratory ...
... Measuring body composition is an important issue to phenotype patients with obesity and to follow the nutritional care efficiency. Bioelectrical Impedance Analysis (BIA) is a simple and rapid technique. However, validity of BIA in patients with obesity remains controversial. Thus, we aimed to evaluate the validity of several BIA equations to assess body composition in a large cohort of patients wi ...
bioelectrical impedance; body fat; body measurements; correlation; dual-energy X-ray absorptiometry; females; lean body mass; longevity; males; men; middle-aged adults; muscles; nutritional status; physical fitness; reference standards
Abstract:
... BACKGROUND & AIMS: Body composition measurement is a valuable tool for assessing nutritional status and physical fitness in a variety of clinical settings. Although bioimpedance analysis (BIA) can easily assess body composition, its accuracy remains unclear. We examined the accuracy of direct segmental multi-frequency BIA technique (DSM-BIA) in assessing different body composition parameters, usin ...
algorithms; body mass index; calorimetry; energy requirements; equations; models; prediction; resting energy expenditure; t-test
Abstract:
... The measurement of resting energy expenditure (REE) is important to assess individual total energy requirements in older subjects. The validity of REE prediction equations in this population has not been thoroughly evaluated and therefore the main aim of this analysis was to assess the accuracy of REE prediction equations in older subjects.Weight, height and body mass index (BMI) were measured. RE ...
bioelectrical impedance; body water; densitometry; humans; lean body mass; magnetism; obesity; women
Abstract:
... Quantitative magnetic resonance (QMR) has previously been shown to both overestimate and underestimate average fat mass (FM) in humans. Eight-electrode bioelectrical impedance analysis (BIA) has previously been found biased as well as successfully validated. We report cross-sectional accuracy of QMR and eight-electrode BIA evaluated with air displacement plethysmography (ADP) as reference method.F ...
Maria Inês Barreto Silva; Ana Paula Medeiros Menna Barreto; Karine Scanci da Silva Pontes; Mariana Silva da Costa; Kelli Trindade de Carvalho Rosina; Edison Souza; Rachel Bregman; Carla M. Prado; Márcia Regina Simas Torres Klein
adults; bioelectrical impedance; body composition; body mass index; cross-sectional studies; equations; females; guidelines; kidney diseases; kidney transplant; males; patients; skeletal muscle
Abstract:
... Bioelectrical impedance analysis (BIA) and anthropometric predictive equations have been proposed to estimate whole-body (SMM) and appendicular skeletal muscle mass (ASM) as surrogate for dual energy X-ray absorptiometry (DXA) in distinct population groups. However, their accuracy in estimating body composition in non-dialysis dependent patients with chronic kidney disease (NDD-CKD) and kidney tra ...
... Although malnutrition remains a global public health concern, and has proved to be a major contributor to death and illness, there has been a foundational lack of a gold standard for diagnostic testing for clinical application. The Global Leadership Initiative on Malnutrition (GLIM) criteria were established to normalize the diagnosis of malnutrition, but their use remains controversial. Therefore ...
antibiotics; children; energy intake; malnutrition; parenteral feeding; patients; protocols; resting energy expenditure
Abstract:
... Adequate nutritional intake is essential during pediatric intensive care admission. We investigated whether achievement of energy intake goals at day 4 after admission and route of nutrition were associated with improved outcome.Observational study using prospectively acquired data. Patients receiving enteral and/or parenteral nutrition were included. The energy intake target range at day 4 after ...
R.D. Eveleens; J.M. Hulst; B.A.E. de Koning; J. van Brakel; D. Rizopoulos; G. Garcia Guerra; I. Vanhorebeek; G. Van den Berghe; K.F.M. Joosten; S.C.A.T. Verbruggen
... In the absence of methodologically sound randomized controlled trials (RCTs), current recommendations for timing and amount of enteral nutrition (EN) in critically ill children are based on observational studies. These studies have associated achievement of a higher EN intake in critically ill children with improved outcome. Inherent to the observational design of these underlying studies, thoroug ...
amino acid composition; diarrhea; energy expenditure; enteral feeding; essential amino acids; feasibility studies; ideal body weight; kidneys; mortality; overfeeding; patients; protein intake; urea
Abstract:
... High protein delivery during early critical illness is associated with lower mortality, while energy overfeeding is associated with higher mortality. Protein-to-energy ratios of traditional enteral formulae are sometimes too low to reach protein targets without energy overfeeding. This prospective feasibility study aimed to evaluate the ability of a new enteral formula with a high protein-to-energ ...
blood serum; body mass index; cardiovascular diseases; cross-over studies; diabetes; etiology; females; fructose; glucose; ingestion; lactate dehydrogenase; males; nitric oxide; obesity; risk; systolic blood pressure; uric acid; volunteers; China
Abstract:
... A rise in fructose consumption has been implicated in the aetiology of obesity, diabetes and cardiovascular disease. Serum uric acid (UA) elevates after fructose ingestion, increasing the risk of cardiovascular disease. However, the impact of fructose ingestion on nitric oxide (NO) has not yet been confirmed. The aim of this study was to investigate the postprandial metabolic and endocrine respons ...
... Postprandial metabolic abnormalities are considered important and independent risk factors for cardiovascular diseases. However, the effects of the Mediterranean diet on postprandial metabolism and the mechanism underpinning the effects on clinical variables have not been exhaustively explored. Therefore, the aims of the present study were to evaluate the acute and medium-term effects (8 weeks) on ...
... Dietary flavonoids, such as those present in black tea, are associated with reduced risk of cardiovascular disease (CVD), possibly through improving nitric oxide (NO) mediated vascular function. The aim of this study was to examine the effect of acute black tea ingestion on cutaneous microvascular function.Twenty healthy participants (58 ± 5 y, 9 men) attended two experimental trials (tea, placebo ...
... Atherosclerosis is an inflammatory disease. Previous studies have suggested the beneficial effects of moderate consumption of alcoholic beverages on reducing cardiovascular risk (CVR). The aim of this study was to evaluate the effects of acute consumption of Andalusian aged wine (AAW) and gin by analyzing the expression of genes related to the appearance and progression of atherosclerosis in men w ...
... It has been previously reported that pasta containing wholegrain sorghum flour exhibits high content of polyphenols and antioxidant capacity and hence might enhance antioxidant status and reduce markers of oxidative stress in vivo; however no clinical studies have yet been reported. Therefore, the present study assessed the effect of pasta containing red or white wholegrain sorghum flour on plasma ...
... Pinolenic acid, a major component (~20%) of pine nut oil, is a dual agonist of the free fatty acid receptors, FFA1 and FFA4, which may regulate release of incretins and ghrelin from the gut. Here, we investigated the acute effects of hydrolyzed pine nut oil (PNO-FFA), delivered to the small intestine by delayed-release capsules, on glucose tolerance, insulin, incretin and ghrelin secretion, and ap ...
Andrew Wilhelmsen; Amanda Davies; Joanne Mallinson; Pardeep Pabla; Robert Jones; Elliott A. Palmer; Warwick B. Dunn; Gordon W. Moran; Francis B. Stephens; Kostas Tsintzas
... Obesity and insulin resistance are associated with an impaired sensitivity to anabolic stimuli such as dietary protein (anabolic resistance). Omega-3 polyunsaturated fatty acids (n-3 PUFA) may be protective against the deleterious effects of saturated fatty acids (SFA) on insulin resistance. However, the contribution of excess fat consumption to anabolic and insulin resistance and the interaction ...
... BACKGROUND & AIMS: Research on young healthy samples suggests that low glycaemic load foods can confer benefits for cognitive performance. The aim was to examine the effects of type 2 diabetes on cognitive function, and to investigate whether consumption of low glycaemic load breakfasts affects cognitive function in adults with type 2 diabetes. METHOD: Memory, psychomotor skill and executive funct ...
Annika Reintam Blaser; Ilse Ploegmakers; Michael Benoit; Mette Holst; Henrik Hojgaard Rasmussen; Rosa Burgos; Alastair Forbes; Jon Shaffer; Simon Gabe; Oivind Irtun; Ronan Thibault; Stanislaw Klek; Steven WM Olde Damink; Marcel van de Poll; Marina Panisic-Sekeljic; Geert Wanten; Loris Pironi; Vladislav Mihnovits; Antonina Britenkova; Kadri Lind; Ivan Pertsev; Gregor Lansche; Anna Simona Sasdelli; Zsolt Bodnar; Francisco Pracca; Italo Bioni; Gintautas Kekstas; Karolina Venlavicute; Pietro Vecchiarelli; Zeljko Krznaric; Ana Kunovic; Ramiro Manzano Nunez; Carlos A. Ordonez; Hanna-Liis Lepp; Charlene Compher; Marianne Aloupis; Nizar Senussi; Ana Zugasti Murillo; María Maíz-Jiménez; Pilar Matia; Carmina Wanden-Berghe; Wojciech Dabrowski; AIF study group
... Intestinal failure (IF) is defined from a requirement or intravenous supplementation due to failing capacity to absorb nutrients and fluids. Acute IF is an acute, potentially reversible form of IF. We aimed to identify the prevalence, underlying causes and outcomes of acute IF.This point-of-prevalence study included all adult patients hospitalized in acute care hospitals and receiving parenteral n ...
... Several hip fracture patients are malnourished, but no study has attempted to determine the optimal nutritional screening tool for predicting functional outcomes. We investigated the association between each nutritional status assessed by four nutritional screening tools at admission and functional outcomes during the postoperative acute phase in hip fracture patients.The Mini Nutritional Assessme ...
analysis of covariance; body weight; breakfast; energy intake; environmental enrichment; food intake; lunch; malnutrition; nutrient requirements; patients; protein intake; regression analysis; stroke
Abstract:
... Malnutrition is common after stroke. We investigated the impact of environmental enrichment strategies on dietary intake and rates of malnutrition in an acute stroke unit.We performed a before-after study. In standard care, meals were delivered to participants’ rooms whilst in the enriched environment, communal meals with assistance were offered and nutritional intake reminders were placed at the ...
... There is convincing clinical evidence to suggest that flavanol-containing foods/beverages are capable of inducing improvements in human vascular function. However, whilst (−)-epicatechin has been tested for efficacy, a full dose-dependency has yet to be established, particularly at doses below 1 mg/kg BW. The current study examined the dose-dependent effects of (−)-epicatechin on human vascular fu ...
Samuel Moncayo; María Insenser; M. Ángeles Martínez-García; Rocío Fuertes-Martín; Núria Amigó-Grau; Francisco Álvarez-Blasco; Manuel Luque-Ramírez; Xavier Correig-Blanchar; Héctor F. Escobar-Morreale
... Acute-phase glycoprotein ¹H-NMR spectroscopy profiles serve as surrogate markers of chronic inflammation in metabolic disorders such as obesity, diabetes and polycystic ovary syndrome (PCOS). The latter is associated with increased height-to-width (H/W) ratios of GlycA and GlycB after fasting, but not to glycoprotein areas, regardless of obesity. We studied the responses to separate glucose, lipid ...
Mediterranean diet; adults; cohort studies; death; dietary recommendations; food frequency questionnaires; mortality; nutrition policy; regression analysis; Israel; Mediterranean region
Abstract:
... There is a substantial body of evidence supporting the health benefits of the Mediterranean diet, which has differing variations across the Mediterranean region. Abbreviated dietary screeners can be adapted and used to assess adherence to the local Mediterranean diet variant. We aimed to describe the process of adapting the Spanish Mediterranean Diet Adherence Screener (MEDAS) for use in Israel, a ...
Hester Vlaardingerbroek; Jorine A. Roelants; Denise Rook; Kristien Dorst; Henk Schierbeek; Andras Vermes; Marijn J. Vermeulen; Johannes B. van Goudoever; Chris H.P. van den Akker
amino acid metabolism; energy intake; glucose; hydroxylation; infants; intravenous injection; issues and policy; leucine; lipids; low birth weight; nutritional intervention; oxidation; parenteral feeding; phenylalanine; protein synthesis; stable isotopes; tyrosine; urea
Abstract:
... An anabolic state can be achieved upon intravenous amino acid administration during the immediate postnatal phase despite a low energy intake. The optimal dosing of amino acid and energy intake has yet to be established. The aim was to quantify the efficacy of early initiation of parenteral lipids and increased amounts of amino acids on metabolism and protein accretion in very low birth weight inf ...
Bifidobacterium; diarrhea; enteral feeding; feces; fluorescence; fructooligosaccharides; humans; immunoglobulin A; in situ hybridization; intestinal microorganisms; inulin; maltodextrins; normal values; patients; placebos; randomized clinical trials; short chain fatty acids
Abstract:
... Patients with diarrhoea during enteral nutrition (EN) have been shown to have low faecal bifidobacteria concentrations. Oligofructose/inulin selectively stimulate the growth of bifidobacteria in healthy humans. This study investigates the effect of additional oligofructose/inulin on the gastrointestinal microbiota, short-chain fatty acids (SCFA) and faecal output in patients receiving EN.Adult pat ...
National Health and Nutrition Examination Survey; adults; men; metabolic syndrome; obesity; prediction; risk; sarcopenia; skeletal muscle; waist circumference; women; Korean Peninsula
Abstract:
... It is unclear whether sarcopenia contributes to the prediction of metabolic dysregulations in addition to that predicted by waist circumference.Subjects consisted of 6832 adult participants in the 2009 Korea National Health and Nutrition Examination Survey, grouped into categories of waist circumference (normal vs. high). Sarcopenia was assessed by appendicular skeletal muscle mass divided by weig ...
... Colorectal cancer (CRC) exhibits a linear progression from normal colonic epithelium, adenoma initiation, carcinoma transformation and even to metastasis. Diet changes might influence carcinogenesis and prognosis. We aimed to determine the effects of vitamin D and calcium on colorectal adenoma incidence, malignancy development and prognosis.Systematic literature searches (PubMed, Embase, and Cochr ...
Down syndrome; body mass index; boys; cerebral palsy; cross-sectional studies; data collection; elderly; girls; hospitals; males; malnutrition; medical records; muscles; nutrition assessment; nutrition risk assessment; patients; screening; underweight; Brazil
Abstract:
... The adductor pollicis muscle thickness (APMT) is a promising method for evaluation of muscle loss and, consequently, malnutrition in adult and elderly patients. However, to date, there have been no studies of its applicability to the pediatric population. Within this context, we sought to evaluate the association of APMT with anthropometric variables, body mass index (BMI), pediatric Subjective Gl ...
anthropometric measurements; body composition; body weight; correlation; cross-sectional studies; dual-energy X-ray absorptiometry; muscles; nutritional status; postmenopause; prediction; women
Abstract:
... Lean mass (LM) is a functional component of body composition and is an important parameter of nutritional status assessment. The adductor pollicis muscle thickness (APMT) has been used as a predictor of LM, but it is not well known if this method presents a higher prediction of LM than simple anthropometric measurements, such as weight. Thus, we aimed to associate APMT (alone and plus weight) with ...
anthropometric measurements; body composition; gender; malnutrition; muscles; normal values; nutritional status; patients; regression analysis; women
Abstract:
... Body composition is important to identify malnutrition, and several anthropometric measurements are used to estimate muscle mass in the clinical practice. This study aimed to assess the adductor pollicis muscle thickness (APMT), its covariates and association with malnutrition in hospitalized surgical patients.APMT was measured in 361 surgical patients in both dominant (DAPMT) and non-dominant (ND ...
Alzheimer disease; appetite; body mass index; body weight changes; caregivers; cognition; comorbidity; deglutition; diabetes mellitus; eating habits; hypertension; males; malnutrition; monitoring; nutrition assessment; nutritional status; obesity; patients; questionnaires
Abstract:
... Recent evidence highlights the effects of obesity, diabetes and hypertension in the development of Alzheimer's disease. Involuntary body weight changes in patients with different stages of dementia can be related to clinical factors of the patient per se or support from their caregivers. Understanding the interactions among factors is important to establish a monitoring paradigm to guide treatment ...
Liisa MacGowan; Elizabeth Smith; Charmaine Elliott-Hammond; Barnaby Sanderson; Dennis Ong; Kathleen Daly; Nicholas A. Barrett; Kevin Whelan; Danielle E. Bear
adults; energy intake; gastrointestinal motility; hospitals; medical records; nutritional adequacy; nutritional support; observational studies; patients; prospective studies; protein intake
Abstract:
... The use of veno-venous extracorporeal membrane oxygenation (vv-ECMO) is increasing in adults with severe respiratory failure. Observational data suggest that there are significant challenges to providing adequate nutrition support for patients on vv-ECMO. We aimed to describe firstly the nutrition support practices in a large single-centre providing vv-ECMO to adults and secondly any association w ...
Ricardo Closa-Monasterolo; Marta Zaragoza-Jordana; Natàlia Ferré; Veronica Luque; Veit Grote; Berthold Koletzko; Elvira Verduci; Fiammetta Vecchi; Joaquin Escribano; R. Closa-Monasterolo; J. Escribano; N. Ferré; M. Gispert-Llauradó; V. Luque; C. Rubio-Torrents; M. Zaragoza-Jordana; J. Beyer; M. Fritsch; G. Haile; U. Handel; I. Hannibal; B. Koletzko; S. Kreichauf; I. Pawellek; S. Schiess; S. Verwied-Jorky; R. von Kries; M. Weber; A. Dobrzańska; D. Gruszfeld; R. Janas; A. Wierzbicka; P. Socha; A. Stolarczyk; J. Socha; C. Carlier; E. Dain; P. Goyens; J.N. Van Hees; J. Hoyos; J.P. Langhendries; F. Martin; P. Poncelet; A. Xhonneux; E. Perrin; C. Agostoni; M. Giovannini; A. Re Dionigi; E. Riva; S. Scaglioni; F. Vecchi; E. Verducci; Childhood Obesity Project Group
Adequate Intakes; Food and Agriculture Organization; World Health Organization; body composition; bone density; bone mineralization; calcium; childhood; childhood obesity; children; clinical trials; correlation; dual-energy X-ray absorptiometry; food intake; food records; genetic factors; guidelines; lumbar spine; medicine; odds ratio; osteopenia; physical activity
Abstract:
... Bone mineralization can be influenced by genetic factors, hormonal status, nutrition, physical activity and body composition. The association of higher calcium (Ca) intake or Ca supplementation with better bone mineral density (BMD) remains controversial. Furthermore, it has been speculated that maintaining long-term adequate Ca intake rather than having a brief supplementation period is more effe ...
Mavil May C. Cervo; David Scott; Markus J. Seibel; Robert G. Cumming; Vasi Naganathan; Fiona M. Blyth; David G. Le Couteur; David J. Handelsman; Rosilene V. Ribeiro; Louise M. Waite; Vasant Hirani
Mediterranean diet; body mass index; bone density; clinical nutrition; cross-sectional studies; cytokines; dual-energy X-ray absorptiometry; food frequency questionnaires; gait; hand strength; humans; regression analysis; risk; telephones
Abstract:
... Mediterranean dietary patterns may exert favourable effects on various health conditions. This study aimed to determine associations of adherence to Mediterranean diet as well as its components, with circulating cytokine levels, musculoskeletal health and incident falls in community-dwelling older men.Seven hundred ninety-four (794) community-dwelling men with mean age 81.1 ± 4.5 years, who partic ...
Mediterranean diet; body mass index; cohort studies; education; energy intake; females; income; osteoarthritis; physical activity; poultry; risk; weight loss; North America
Abstract:
... There is a paucity of data investigating the relationship between the Mediterranean diet and frailty, with no data among North American people. We aimed to investigate if adherence to a Mediterranean diet is associated with a lower incidence of frailty in a large cohort of North American people.This study included subjects at higher risk or having knee osteoarthritis. Adherence to the Mediterranea ...
... The Mediterranean diet appears to be beneficial for several medical conditions, but data regarding osteoarthritis (OA) are not available. The aim of this study was to investigate if adherence to the Mediterranean diet is associated with a lower prevalence of OA of the knee in a large cohort from North America.4358 community-dwelling participants (2527 females; mean age: 61.2 years) from the Osteoa ...
... The relationship between healthy lifestyle factors and mortality in people with type 2 diabetes is unclear. The purpose of this study was to examine whether healthy lifestyle factors are associated with mortality in people with type 2 diabetes.We prospectively studied 1163 men with type 2 diabetes from the Physicians' Health Study. Lifestyle factors consisted of currently not smoking, moderate dri ...
body mass index; carbohydrate intake; carbohydrates; case-control studies; cohort studies; developing countries; dietary carbohydrate; eating habits; energy; food intake; glioma; lipids; low carbohydrate diet; observational studies; protein intake; proteins
Abstract:
... Observational studies that investigated the association between adherence to low carbohydrate diet and odds of glioma are sparse. This is particularly relevant in developing countries where dietary carbohydrate intake is very high.This study was, therefore, conducted to investigate the association between adherence to low carbohydrate dietary pattern and odds of glioma among Iranian adults.In this ...
... Colorectal cancer (CRC) has become a major concern due to industrialization and dietary changes generated by it. Many of the components of the DASH (Dietary Approach to Stop Hypertension) diet are associated with the risk of CRC. However, the relationship between DASH dietary pattern and CRC has not been studied yet in a systematic review and meta-analysis. The present study was conducted to revie ...
... Adolescence is a critical period for neurodevelopment, it is characterised by the establishment of behavioural patterns that can affect children's physical, mental and cognitive health, both immediately and later in life.The aim of the present research was to examine the association between adherence to the Mediterranean diet (MeD) and academic performance, as well as to analyze the moderating rol ...
Meropi D. Kontogianni; Nafsika Tileli; Aikaterini Margariti; Michael Georgoulis; Melanie Deutsch; Dina Tiniakos; Elisabeth Fragopoulou; Rodessa Zafiropoulou; Yannis Manios; George Papatheodoridis
... Nutrition has been proposed as a potential environmental factor affecting the risk of non-alcoholic fatty liver disease (NAFLD). In the present study, the impact of adherence to the Mediterranean diet (MD) on the presence and severity of NAFLD was explored.Seventy-three consecutive adult patients with recent NAFLD diagnosis were included. Adherence to the MD was estimated with MedDietScore. Demogr ...
Mediterranean diet; abdominal fat; adults; body mass index; cross-sectional studies; eating habits; obesity; patients; physical activity; regression analysis; ultrasonography; waist circumference; waist-to-height ratio; women
Abstract:
... & aim: Adherence to the Mediterranean dietary pattern (MDP) is inversely related with abdominal adiposity as detected by waist circumference but the specific association to subcutaneous and visceral abdominal tissue has not been investigated. To this purpose we evaluated the association between MDP, visceral (VAT) and subcutaneous (SAT) abdominal tissue in a large sample of Italian adults.A cross- ...
Mediterranean diet; anxiety; binge eating disorder; binging; body mass index; butter; cakes; confidence interval; cream; education; food frequency questionnaires; gender; nutritional status; odds ratio; olive oil; patients; physical activity; prospective studies; risk; risk reduction; sweets; waist circumference; weight loss; women
Abstract:
... The key factors influencing the development of Binge Eating Disorder (BED) are not well known. Adherence to the Mediterranean diet (MD) has been suspected to reduce the risk of several mental illnesses such as depression and anxiety. There are no existing studies that have examined the relationships between BED and MD.Cross-sectional study of 1472 participants (71.3% women; mean age: 44.8 ± 12.7) ...
Mediterranean diet; body mass index; case-control studies; cohort studies; eating habits; energy intake; food frequency questionnaires; food intake; glioma; mortality; patients; regression analysis; risk; Iran
Abstract:
... Although Mediterranean diet (MD) was associated with a lower risk of mortality and cancer, no data are available investigating the association between adherence to the MD and risk of glioma.In this case–control study, we enrolled a total of 128 newly diagnosed patients with glioma, confirmed by pathological assessment, and 256 hospital-based controls from 2009 to 2011 in Tehran, Iran. A valid and ...
... The World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) updated their cancer prevention recommendations in 2018. Adherence to these recommendations has been associated with lower cancer risk and mortality. However, adherence in relation to Cancer of Unknown Primary (CUP) risk has not been studied. This study investigates whether adherence to the WCRF/AICR recommenda ...
... BACKGROUND & AIM: Majority of the National Institute of Clinical Excellence (NICE) nutrition guidance recommendations were based on Grade D evidence due to absence of randomised controlled trials. The aim was to assess outcomes of parenteral nutrition (PN) administration when the guidance was adhered to. METHODS: The prospective study included patients referred for PN. Patients were divided into t ...
adipocytes; adipose tissue; adiposity; body mass index; breast neoplasms; clinical nutrition; computed tomography; fibrosis; health services; inflammation; lipid content; mortality; prognosis; risk; standard deviation; vertebrae; California
Abstract:
... Computed tomography (CT) scans can measure quantity and distribution of adipose tissue, which are associated with breast cancer prognosis. As a novel prognostic marker, radiodensity of adipose tissue has been examined in multiple cancer types, but never in breast cancer. Lower density indicates larger adipocytes with greater lipid content, whereas higher density can reflect inflammation, fibrosis, ...
... It is crucial to have simple and appropriate measures to identify people with adiposity-related risk. We compared the associations of mortality with body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), and body fat percentage (BF%) in a prospective cohort.A total of 463,002 adults were recruited between 1996 and 2017. Vital data were obtained from the National Death Regis ...
25-hydroxycholecalciferol; autoantigens; c-peptide; glutamic acid; interferon-gamma; islets of Langerhans; mononuclear leukocytes; patients; tyrosine; vitamin D deficiency
Abstract:
... We investigated whether improving 25-hydroxyvitamin D status in young type 1A diabetic patients reduces reactivity of peripheral blood mononuclear cells against islet autoantigens and associates with beta-cell functional changes.Eight patients with 25-hydroxyvitamin D deficiency (<20 ng/ml), out of 15 consecutive young type 1A diabetic subjects received 25-hydroxyvitamin D3 to achieve and maintain ...
Annika Bargetzi; Nora Emmenegger; Simone Wildisen; Manuela Nickler; Laura Bargetzi; Lara Hersberger; Stephan Segerer; Nina Kaegi-Braun; Pascal Tribolet; Filomena Gomes; Claus Hoess; Vojtech Pavlicek; Stefan Bilz; Sarah Sigrist; Michael Brändle; Christoph Henzen; Robert Thomann; Jonas Rutishauser; Drahomir Aujesky; Nicolas Rodondi; Jacques Donzé; Zeno Stanga; Beat Mueller; Philipp Schuetz
... Patients with chronic kidney disease (CKD) are at substantial risk of malnutrition, which negatively affects clinical outcomes. We investigated the association of kidney function assessed at hospital admission and effectiveness of nutritional support in hospitalized medical patients at risk of malnutrition.This is a secondary analysis of an investigator-initiated, randomized-controlled, Swiss mult ...
adults; clinical nutrition; coasts; cross-sectional studies; education; family size; head circumference; income; occupations; phenotype; protein energy malnutrition; questionnaires; Kenya
Abstract:
... To determine the characteristics of adults who survived early life malnutrition (ELM) and the possible associated factors. The setting is an impoverished community in Kenya. The coastal region of Kenya has a high prevalence of acute protein-energy-malnutrition and stunting.Observational cross-sectional survey where 872 skeletally mature adults of African origin, were surveyed in a period of three ...
... Homocystinuria due to cystathionine beta synthase (CBS) deficiency presents with a wide clinical spectrum. Treatment by the enteral route aims at reducing homocysteine levels by using vitamin B6, possibly methionine-restricted diet, betaine and/or folate and vitamin B12 supplementation. Currently no nutritional guidelines exist regarding parenteral nutrition (PN) under acute conditions.Exhaustive ...
Elisabeth Blüthner; Jan Bednarsch; Ulrich-Frank Pape; Mirjam Karber; Sebastian Maasberg; Undine A. Gerlach; Andreas Pascher; Bertram Wiedenmann; Johann Pratschke; Martin Stockmann
... Intestinal failure associated liver disease (IFALD) is one of the leading complications and causes of deaths in adult patients receiving home parenteral nutrition for chronic intestinal failure (CIF). Early diagnosis of IFALD is key to alleviate the progression of hepatic dysfunction. The aim of this study was to evaluate the capability of noninvasive liver function tests.90 adult patients with CI ...
COVID-19 infection; anabolism; body composition; body mass index; body weight; calf circumference; catabolism; clinical nutrition; creatine; hand strength; health services; immune response; immune system; leucine; malnutrition; mitochondria; muscles; omega-3 fatty acids; patients; physical activity; polyphenols; skeletal muscle; ultrasonics
Abstract:
... Low muscle mass and malnutrition are prevalent conditions among adults of all ages, with any body weight or body mass index, and with acute or chronic conditions, including COVID-19. This article synthesizes the latest research advancements in muscle health and malnutrition, and their impact on immune function, and clinical outcomes. We provide a toolkit of illustrations and scientific information ...
... Nutritional therapy is a viable therapeutic option for the treatment of Crohn disease (CD). Therefore improving nutritional therapy would greatly benefit CD patients. The aim of this study was to define the anti-inflammatory properties of a novel nutritional polymeric formula (PF) in comparison to a currently available standard PF.Dextran sodium sulfate (DSS) was utilized to induce colitis in C57B ...
... Studies on the impact of supplementation cessation are lacking. We investigated the effect of iron and iron/zinc supplementation and cessation of this intervention on iron status parameters.The study was conducted on 6-week male Wistar rats, in 3 stages: 4-week adaptation to the diets: C – control (AIN-93M) and D – iron deficient (mineral mix without iron); 4-week supplementation: 10-times more ir ...
National Health and Nutrition Examination Survey; age; alanine transaminase; alcohol drinking; analysis of covariance; aspartate transaminase; blood serum; confidence interval; databases; diabetes; educational status; eggs; energy intake; fatty liver; gender; hypertension; income; liver; men; models; odds ratio; pathogenesis; physical activity; poverty; races; regression analysis; risk factors; triacylglycerols
Abstract:
... We evaluated the association of egg consumption with liver tests (LTs) and non-alcoholic fatty liver disease (NAFLD). This relationship is poorly documented.The National Health and Nutrition Examination Survey (NHANES, 2005–2010) database was used. Analysis of covariance, adjusted linear and logistic regression models were used.Of the 14,369 participants, 46.8% were men and 45.2% had NAFLD. After ...
... We have sought to develop proper and useful indices for muscle quality measurements other than muscle attenuation (Hounsfield unit; HU) and to determine the diagnostic cutoff points for myosteatosis by using those indices measured at the L3 lumbar vertebrae level by CT scan.This cross-sectional analysis included 20,664 healthy adult subjects (12,697 men and 7967 women) who underwent abdominal CT s ...
amino acid transporters; elderly; essential amino acids; humans; ingestion; men; messenger RNA; muscles; protein synthesis; skeletal muscle; strength training
Abstract:
... BACKGROUND & AIMS: Amino acid transporters have been proposed as regulators of protein synthesis. The primary aim of this study was to determine whether amino acid transporter expression is increased in human muscle following resistance exercise (RE) coupled with essential amino acid (EAA) ingestion, and whether a differential response occurs with aging. Secondly, we aimed to compare this response ...
clinical nutrition; cross-sectional studies; diagnostic techniques; etiology; leadership; lean body mass; malnutrition; nutrition risk assessment; patients; phenotype; surgery; weight loss
Abstract:
... The Global Leadership Initiative on Malnutrition (GLIM) has suggested a process for the diagnosis of malnutrition. The process consists of applying an existing screening tool for malnutrition screening, followed by malnutrition diagnostics, and finally categorization of malnutrition severity (moderate or severe) according to specific GLIM criteria. However, it is not known how well the GLIM proces ...
... Densitometry (Siri's and Brožek's equations), hydrometry (by the deuterium dilution technique), and dual-energy X-ray absorptiometry (DXA) are three methods for estimating body composition. However, because they are all based on certain assumptions, they may not be applicable to aged and obese subjects due to changes in their body composition. Hence, the validity of these “laboratory methods” coul ...
... The Global Leadership Initiative on Malnutrition (GLIM) criteria is a step-wise process including a screening tool of choice for risk assessment of malnutrition before assessment of diagnosis and grading of malnutrition severity. The agreement between GLIM and the established malnutrition assessment method Patient Generated-Subjective Global Assessment (PG-SGA) is uncertain. Also, several aspects ...
Western blotting; body weight; colon; drinking water; glutamate-ammonia ligase; glutamine; lactulose; mannitol; models; neonates; nutritional intervention; permeability; protein synthesis; proteins; pups; rats; tight junctions
Abstract:
... BACKGROUND & AIMS: Increased intestinal permeability of Irritable bowel syndrome (IBS) patients has been recently associated with a decreased level of glutamine synthetase. Neonatal maternal deprivation (NMD) is considered as an IBS-like model. The aim of our study was to investigate whether early nutritional intervention with glutamine may attenuate the deleterious impact of early life stress on ...
Hester Vlaardingerbroek; Henk Schierbeek; Denise Rook; Marijn J. Vermeulen; Kristien Dorst; Andras Vermes; Johannes B. van Goudoever; Chris H.P. van den Akker
... Albumin is one of the most important plasma proteins and plays a key role in many physiologic processes, such as preserving colloid osmotic pressure, scavenging radicals, and binding and transporting bilirubin, hormones, and drugs. However, albumin concentrations are often low in preterm infants during the first days of life.We hypothesized that early parenteral lipid and high-dose amino acid (AA) ...
adolescents; albumins; body mass index; children; energy; glucose; infants; insulin; labeling techniques; leucine; total parenteral nutrition
Abstract:
... BACKGROUND & AIMS: To investigate the effects of glucose, parenteral amino acids, and intravenous insulin on albumin synthesis rates in critically ill children. METHODS: Two studies were performed in 8 post-surgical infants (age 9.8 ± 1.9 months; weight 9.5 ± 1.1 kg) and 9 septic adolescents (age 15 ± 1 yr; BMI 23 ± 4 kg m⁻²), respectively. All received a primed, constant, tracer infusion with [1- ...
... Chronic liver diseases, including hepatocellular carcinoma (HCC), lead to an imbalance in energy metabolism. The non-protein respiratory quotient (npRQ), which estimates energy malnutrition, can be evaluated using an indirect calorimeter; however, npRQ measurement is limited in routine work. This study aimed to investigate the relationship between the albumin–bilirubin (ALBI) score and npRQ in pat ...
... Controversy exists on the association between alcohol consumption and risk of heart failure (HF). We carried out a meta-analysis to summarize available prospective data on alcohol consumption and HF.We searched PubMed for relevant studies published until January 1, 2017. Relative risk (RR) estimates from individual studies were pooled in a random-effects meta-analysis.A total of 13 prospective stu ...
... Epidemiological evidence suggests that alcohol consumption is related to the incidence and development of metabolic syndrome. However, data on this issue are unstable and controversial. We conducted a meta-analysis to provide a quantitative assessment of the association between alcohol intake and risk of metabolic syndrome.We searched the Pubmed and Embase databases up to May 2013 to identify pros ...
alcohol drinking; alcohols; body mass index; confidence interval; education; elderly; lifestyle; men; odds ratio; risk; wines; women; Mediterranean region; Spain
Abstract:
... Several studies have found that moderate alcohol intake is associated with lower risk of functional limitations in older adults. However, no previous investigation has assessed this association in older adults from Mediterranean countries, who show characteristic drinking patterns.Data were taken from the UAM and the Seniors-ENRICA cohorts in Spain, comprising community-dwelling people aged ≥60 ye ...
Yian Gu; Nikolaos Scarmeas; Erica Eaton Short; José A. Luchsinger; Charles DeCarli; Yaakov Stern; Jennifer J. Manly; Nicole Schupf; Richard Mayeux; Adam M. Brickman
... Evidence suggests that consuming light-to-moderate amounts of alcohol reduces the risk of dementia and is associated better cognitive function and less cardiovascular disease, relative to those consuming no or heavy alcohol. There are only minimal data on the association between alcohol and brain magnetic resonance imaging (MRI) markers. This study aimed to examine the association between alcohol ...
... To investigate potential biases that exist in available epidemiological evidence resulting in negative associations or underestimation of cardiovascular (CV) risk associated with alcohol consumption.UK Biobank involved baseline data collection from 22 assessment centres across the United Kingdom. The cohort consisted of 333 259 alcohol consumers and 21 710 never drinkers. Participants were followe ...
... Aliphatic polyamines are a family of polycationic molecules derived from decarboxylation of the amino acid ornithine that classically comprise three molecules: putrescine, spermidine and spermine. In-cell polyamine homeostasis is tightly controlled at key steps of cell metabolism. Polyamines are involved in an array of cellular functions from DNA stabilization, and regulation of gene expression to ...
Gianni Biolo; Filippo Giorgio Di Girolamo; Martina Heer; Mariella Sturma; Sara Mazzucco; Francesco Agostini; Roberta Situlin; Pierandrea Vinci; Mauro Giordano; Judith Buehlmeier; Petra Frings-Meuthen; Filippo Mearelli; Nicola Fiotti
... Physical inactivity is associated with lean body mass wasting, oxidative stress and pro-inflammatory changes of cell membrane lipids. Alkalinization may potentially counteract these alterations. We evaluated the effects of potassium bicarbonate supplementation on protein kinetics, glutathione status and pro- and anti-inflammatory polyunsaturated fatty acids (PUFA) in erythrocyte membranes in human ...
alternative medicine; appetite; drug therapy; dyspnea; gastrointestinal system; health care workers; medicine; nausea; neoplasms; patients; quality of life; questionnaires; sleep
Abstract:
... Chemotherapy-induced gastrointestinal (GI) toxicities often impair quality-of-life (QOL) and require reduction of the chemotherapy dose intensity. We explored the effects of a complementary integrative medicine (CIM) therapeutic process, administered in conjunction with conventional supportive care, on GI-related symptoms and concerns in patients undergoing chemotherapy.We conducted a prospective, ...