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Food and chemical toxicology
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Food and chemical toxicology
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2018
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bioactive compounds
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- Author:
- Daniela Ribeiro; Marisa Freitas; Artur M.S. Silva; Félix Carvalho; Eduarda Fernandes
- Source:
- Food and chemical toxicology 2018 v.120 pp. 681-699
- ISSN:
- 0278-6915
- Subject:
- antioxidants; bioactive compounds; carbonyl compounds; carotenoids; diet; humans; lipids; nitrogen; oxidation; oxidative stress; oxygen; plant pigments; toxicology
- Abstract:
- ... Carotenoids are lipid soluble plant pigments that make part of human daily diet. These compounds are able to react with diverse reactive species and originate a myriad of oxidation products that have similar or even more reactivity than their parent compounds. These products may be short-chain carbonyl compounds and, the commonly designated, apo-carotenoids. The effects fo these products in the hu ...
- DOI:
- 10.1016/j.fct.2018.07.060
- https://doi.org/10.1016/j.fct.2018.07.060
- Author:
- Fangfang Lang; Jinfeng Qu; Haiqin Yin; Lanyu Li; Yuanyuan Zhi; Yanping Liu; Zhenghui Fang; Enkui Hao
- Source:
- Food and chemical toxicology 2018 v.121 pp. 631-638
- ISSN:
- 0278-6915
- Subject:
- Angelica sinensis; animal ovaries; antioxidant activity; apoptosis; bioactive compounds; cell viability; dose response; epigenetics; flow cytometry; glutamate-cysteine ligase; humans; mitochondria; neoplasm cells; ovarian neoplasms; oxidative stress; quinones; small interfering RNA; toxicology; transferases; uridine diphosphate
- Abstract:
- ... Z-Ligustilide is the most potent bioactive component of Angelica sinensis, which is widely used in Chinese traditional medicine. Z-Ligustilide selectively affected ovarian cancer cell survival in a dose dependent manner. Z-Ligustilide induced apoptotic cell death was determined by flow cytometry. We also demonstrated that apoptotic cell death was triggered by Z-Ligustilideinduced oxidative stress ...
- DOI:
- 10.1016/j.fct.2018.09.041
- https://doi.org/10.1016/j.fct.2018.09.041
- Author:
- Rosa Palmeri; Lucia Parafati; Cristina Restuccia; Biagio Fallico
- Source:
- Food and chemical toxicology 2018 v.118 pp. 355-360
- ISSN:
- 0278-6915
- Subject:
- Opuntia; antioxidant activity; bacteria; beef; bioactive compounds; cold storage; color; dipping; food preservation; food spoilage; fruit extracts; fruits; microbial growth; polyphenols; shelf life; storage time; texture; toxicology
- Abstract:
- ... The research aimed to expand the knowledge on the use of natural bioactive compounds for food preservation. First-crop fruit of prickly pear were subjected to water extraction and evaluated for total polyphenol content, antioxidant activity, in vitro antimicrobial performance against food spoilage and pathogenic bacteria, and betacyanin and betaxanthin content.The extract was then applied by dippi ...
- DOI:
- 10.1016/j.fct.2018.05.044
- https://doi.org/10.1016/j.fct.2018.05.044
- Author:
- Francesca Giampieri; José L. Quiles; Francisco J. Orantes-Bermejo; Massimiliano Gasparrini; Tamara Y. Forbes-Hernandez; Cristina Sánchez-González; Juan Llopis; Lorenzo Rivas-García; Sadia Afrin; Alfonso Varela-López; Danila Cianciosi; Patricia Reboredo-Rodriguez; Cristina Torres Fernández-Piñar; Ruben Calderón Iglesias; Roberto Ruiz; Silvia Aparicio; Jorge Crespo; Luis Dzul Lopez; Jianbo Xiao; Maurizio Battino
- Source:
- Food and chemical toxicology 2018 v.112 pp. 126-133
- ISSN:
- 0278-6915
- Subject:
- antineoplastic activity; antioxidant activity; beeswax; bioactive compounds; byproducts; carbohydrates; cytotoxicity; dose response; flavonoids; hepatoma; human cell lines; human health; in vivo studies; liver; mitochondria; polyphenols; recycling; viability
- Abstract:
- ... During the process of beeswax recycling, many industrial derivatives are obtained. These matrices may have an interesting healthy and commercial potential but to date they have not been properly studied. The aim of the present work was to evaluate the proximal and phytochemical composition, the antioxidant capacity and cytotoxic effects of two by-products from beeswax recycling process named MUD 1 ...
- DOI:
- 10.1016/j.fct.2017.12.041
- https://doi.org/10.1016/j.fct.2017.12.041
- Author:
- Ammad Ahmad Farooqi; Sumbul Khalid; Fatima Tahir; Uteuliev Yerzhan Sabitaliyevich; Ilhan Yaylim; Rukset Attar; Baojun Xu
- Source:
- Food and chemical toxicology 2018 v.119 pp. 98-105
- ISSN:
- 0278-6915
- Subject:
- Momordica charantia; anti-inflammatory activity; antineoplastic activity; bioactive compounds; carcinogenesis; cell cycle; cell lines; drugs; health promotion; mice; neoplasm cells; neoplasms; precision medicine; regulatory proteins; signal transduction; toxicology
- Abstract:
- ... Research over decades has progressively explored pharmacological actions of bitter gourd (Momordica charantia). Biologically and pharmacologically active molecules isolated from M. charantia have shown significant anti-cancer activity in cancer cell lines and xenografted mice. In this review spotlight was set on the bioactive compounds isolated from M. charantia that effectively inhibited cancer d ...
- DOI:
- 10.1016/j.fct.2018.05.024
- https://doi.org/10.1016/j.fct.2018.05.024
- Author:
- Dorota Wrześniok; Zuzanna Rzepka; Michalina Respondek; Artur Beberok; Jakub Rok; Karolina Szczepanik; Ewa Buszman
- Source:
- Food and chemical toxicology 2018 v.120 pp. 566-570
- ISSN:
- 0278-6915
- Subject:
- apoptosis; beverages; bioactive compounds; caffeine; cell lines; cell viability; chemoprevention; colorimetry; epidemiological studies; glutathione; homeostasis; humans; melanocytes; melanoma; public health; risk; thiols; toxicology
- Abstract:
- ... Coffee is one of the most popular beverages consumed worldwide and therefore even small effects of coffee bioactive compounds on cellular homeostasis could have a large impact on public health. Recent cohort health studies have shown an impressive inverse correlation between caffeinated coffee consumption and malignant melanoma risk. The aim of presented study was to examine the effect of caffeine ...
- DOI:
- 10.1016/j.fct.2018.07.049
- https://doi.org/10.1016/j.fct.2018.07.049
- Author:
- Graziela Bragueto Escher; Jânio Sousa Santos; Neiva Deliberali Rosso; Mariza Boscacci Marques; Luciana Azevedo; Mariana Araújo Vieira do Carmo; Heitor Daguer; Luciano Molognoni; Leonardo do Prado-Silva; Anderson S. Sant'Ana; Marcia Cristina da Silva; Daniel Granato
- Source:
- Food and chemical toxicology 2018 v.118 pp. 439-453
- ISSN:
- 0278-6915
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Centaurea cyanus; anthocyanins; antihypertensive effect; antioxidant activity; bioactive compounds; cell death; cell lines; corolla; coumarin; cytotoxicity; ferulic acid; functional properties; inhibitory concentration 50; isoquercitrin; lipid peroxidation; p-coumaric acid; pH; plant extracts; reactive oxygen species; statistical analysis; temperature
- Abstract:
- ... This study aimed to optimise the experimental conditions of extraction of the phytochemical compounds and functional properties of Centaurea cyanus petals. The following parameters were determined: the chemical composition (LC-ESI-MS/MS), the effects of pH on the stability and antioxidant activity of anthocyanins, the inhibition of lipid peroxidation, antioxidant activity, anti-hemolytic activity, ...
- DOI:
- 10.1016/j.fct.2018.05.046
- https://doi.org/10.1016/j.fct.2018.05.046
- Author:
- Andrei Mocan; Alina Diuzheva; Simone Carradori; Vasil Andruch; Chiara Massafra; Cadmiel Moldovan; Cristian Sisea; Jacobus P. Petzer; Anél Petzer; Susi Zara; Guya Diletta Marconi; Gokhan Zengin; Gianina Crișan; Marcello Locatelli
- Source:
- Food and chemical toxicology 2018 v.119 pp. 189-198
- ISSN:
- 0278-6915
- Subject:
- Prunus domestica; alpha-glucosidase; bioactive compounds; cultivars; cytotoxicity; enzyme inhibition; fibroblasts; food industry; humans; leaves; liquid-phase microextraction; microwave treatment; phenolic compounds; quantitative analysis; toxicology
- Abstract:
- ... In the present work, fourteen cultivars of Prunus domestica were analyzed to investigate their phenolic pattern with the purpose of using the leaves as potential resources of bioactive compounds in the pharmaceutical and food industry. Microwave-assisted extraction (MAE), dispersive liquid–liquid microextraction and sugaring-out liquid–liquid extraction techniques were optimized in order to obtain ...
- DOI:
- 10.1016/j.fct.2018.04.045
- https://doi.org/10.1016/j.fct.2018.04.045
- Author:
- Abishek B. Santhakumar; Maurizio Battino; José M. Alvarez-Suarez
- Source:
- Food and chemical toxicology 2018 v.113 pp. 49-65
- ISSN:
- 0278-6915
- Subject:
- antioxidant activity; atherosclerosis; bioactive compounds; bioavailability; cardioprotective effect; chronic diseases; clinical trials; epidemiological studies; fruits; hemostasis; lipid metabolism; longevity; polyphenols; toxicology; vegetables
- Abstract:
- ... Epidemiological studies have demonstrated that nutritional habits, like those based on high consumption of fruits and vegetables, have been associated with a longer life expectancy and a significant decrease in the incidence and prevalence of several chronic diseases with inflammatory basis, such as cardiovascular diseases (CVD). This beneficial activity has been related to the content of several ...
- DOI:
- 10.1016/j.fct.2018.01.022
- https://doi.org/10.1016/j.fct.2018.01.022
- Author:
- Huifang Ge; Yazhen Chen; Jicheng Chen; Jingjing Tian; Xiaofeng Liang; Lei Chen
- Source:
- Food and chemical toxicology 2018 v.119 pp. 417-424
- ISSN:
- 0278-6915
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Ligusticum sinense; Oriental traditional medicine; antioxidant activity; bioactive compounds; cardiovascular diseases; digestion; dose response; ethanol; ferulic acid; free radical scavengers; hydroxyl radicals; intestines; liquids; oxidative stress; polyphenols; pyrazines; rhizomes; toxicology
- Abstract:
- ... The Rhizome of Ligusticum chuanxiong Hort, a traditional Chinese medicine, is widely used to treat cardiovascular diseases and attenuate oxidative stress. The main bioactive compounds including tetramethylpyrazine (TMP), polyphenols, ferulic acid have been reported to be responsible for these effects. This study was to evaluate the influence of Ligusticum chuanxiong extraction (LCE) in mimic gastr ...
- DOI:
- 10.1016/j.fct.2017.12.035
- https://doi.org/10.1016/j.fct.2017.12.035
- Author:
- Milda Pukalskienė; Gražina Slapšytė; Veronika Dedonytė; Juozas Rimantas Lazutka; Jūratė Mierauskienė; Petras Rimantas Venskutonis
- Source:
- Food and chemical toxicology 2018 v.113 pp. 303-313
- ISSN:
- 0278-6915
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Agrimonia; Ames test; DNA; DNA damage; Filipendula; Salmonella; antioxidant activity; antioxidants; bioactive compounds; comet assay; flavonoids; functional foods; genotoxicity; herbs; humans; lymphocytes; mass spectrometry; micronucleus tests; mutagens; mutation; phenolic acids; phenylpropanoids; plant extracts; traditional medicine; ultra-performance liquid chromatography
- Abstract:
- ... The species of Agrimonia and Filipendula have been traditionally used in folk medicine as anti-inflammatory herbs. This study extends the knowledge on bioactivities of F. palmata, A. eupatoria, A. procera, F. ulmaria and F. vulgaris by comprehensive characterization of their methanolic extracts. Antioxidant properties of extracts were evaluated by DPPH• (2,2-diphenyl-1-picrylhydrazyl), ABTS•+ 2,2′ ...
- DOI:
- 10.1016/j.fct.2017.12.031
- https://doi.org/10.1016/j.fct.2017.12.031
- Author:
- S.A. Petropoulos; A. Karkanis; N. Martins; I.C.F.R. Ferreira
- Source:
- Food and chemical toxicology 2018 v.114 pp. 155-169
- ISSN:
- 0278-6915
- Subject:
- basins; bioactive compounds; biosynthesis; climate change; halophytes; herbs; indigenous species; pharmaceutical industry; salinity; secondary metabolites; toxicology; traditional medicine
- Abstract:
- ... Wild native species are usually grown under severe and stressful conditions, while a special category includes halophytic species that are tolerant to high salinity levels. Native halophytes are valuable sources of bioactive molecules whose content is higher in saline than normal conditions, since the adaptation to salinity mechanisms involve apart from changes in physiological functions the biosy ...
- DOI:
- 10.1016/j.fct.2018.02.031
- https://doi.org/10.1016/j.fct.2018.02.031
- Author:
- Laércio Galvão Maciel; Mariana Araújo Vieira do Carmo; Luciana Azevedo; Heitor Daguer; Luciano Molognoni; Mereci Mendes de Almeida; Daniel Granato; Neiva Deliberali Rosso
- Source:
- Food and chemical toxicology 2018 v.113 pp. 187-197
- ISSN:
- 0278-6915
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Hibiscus sabdariffa; antioxidant activity; ascorbic acid; bioactive compounds; calyx; cell lines; color; cytotoxicity; electrospray ionization mass spectrometry; inhibitory concentration 50; lethal concentration 50; liquid chromatography; myrtillin; neoplasm cells; pH; temperature
- Abstract:
- ... Hibiscus sabdariffa calyx is a rich source of anthocyanins and other bioactive compounds but no study reported the effects of experimental conditions on the extraction of these chemical compounds. Therefore, the effects of time and extraction temperature on the bioactive compounds and antioxidant activity of Hibiscus sabdariffa calyx were evaluated. In addition, the effects of copigmentation and p ...
- DOI:
- 10.1016/j.fct.2018.01.053
- https://doi.org/10.1016/j.fct.2018.01.053
- Author:
- Azzurra Stefanucci; Gokhan Zengin; Marcello Locatelli; Giorgia Macedonio; Chin-Kun Wang; Ettore Novellino; M.Fawzi Mahomoodally; Adriano Mollica
- Source:
- Food and chemical toxicology 2018 v.118 pp. 181-189
- ISSN:
- 0278-6915
- Subject:
- Capparis spinosa; acetylcholinesterase; active ingredients; antioxidant activity; bioactive compounds; buds; cholinesterase; chromatography; enzyme inhibition; essential oils; fatty acids; free radical scavengers; medicinal plants; phenolic compounds; provenance; rutin; toxicology; Italy; Morocco; Turkey (country)
- Abstract:
- ... Capparis spinosa L. (caper), is a traditionally used medicinal plant and widely studied for its biological properties. We aimed for the first time to compare the biological and phenolic fingerprints of C. spinosa buds, collected from Morocco, Turkey, and Italy. Phenolic compounds, fatty acids, and essential oils were profiled by chromatographic techniques. Enzymes inhibitory activities of differen ...
- DOI:
- 10.1016/j.fct.2018.05.003
- https://doi.org/10.1016/j.fct.2018.05.003
- Author:
- Marina Fidelis; Jânio Sousa Santos; Graziela Bragueto Escher; Mariana Vieira do Carmo; Luciana Azevedo; Marcia Cristina da Silva; Predrag Putnik; Daniel Granato
- Source:
- Food and chemical toxicology 2018 v.120 pp. 479-490
- ISSN:
- 0278-6915
- Subject:
- lipid peroxidation; 2,2-diphenyl-1-picrylhydrazyl; high performance liquid chromatography; flavonoids; brain; antihypertensive effect; toxicology; peptidyl-dipeptidase A; principal component analysis; bioassays; egg yolk; bioactive compounds; rats; resveratrol; antioxidant activity; ethanol; antioxidants; phenolic acids; laboratory animals; Myrciaria dubia; nutritive value; functional properties; seed coat; pulp
- Abstract:
- ... Camu-camu (Myrciaria dubia) pulp, seeds, and skin are widely known because of their nutritional properties. However, the seed coat has never been studied as a source of bioactive compounds. Herein, we characterized the phenolic composition, the antioxidant activity, and inhibition of angiotensin-converting enzyme (ACE) of three different extracts (water, propanone, and ethanol) from this residue a ...
- DOI:
- 10.1016/j.fct.2018.07.043
- https://doi.org/10.1016/j.fct.2018.07.043
- Author:
- Xiao-Jing Hu; You-Bo Zhang; Zi-Jing Zhao; Lei Zhang; Qi Wang; Xiu-Wei Yang
- Source:
- Food and chemical toxicology 2018 v.111 pp. 385-392
- ISSN:
- 0278-6915
- Subject:
- Cullen corylifolium; acetates; bioactive compounds; biotransformation; carboxylation; cell lines; cytotoxicity; epoxidation reactions; fruits; humans; hydroxylation; inhibitory concentration 50; liver microsomes; medicinal properties; metabolic detoxification; metabolites; oxidation; rats; tandem mass spectrometry
- Abstract:
- ... Bakuchiol, one of bioactive compounds isolated from the dried ripe fruits of Psoralea corylifolia L., possesses a variety of pharmacological activities. In this study, the metabolites of bakuchiol in rat liver microsomes as well as their cytotoxicities were studied. A total of eight metabolites were isolated and identified as 14-carboxylbakuchiol (M1), 14,15-dihydroxybakuchiol (M2), 12,13-dihydrox ...
- DOI:
- 10.1016/j.fct.2017.11.048
- https://doi.org/10.1016/j.fct.2017.11.048
- Author:
- Radu Claudiu Fierascu; Milen I. Georgiev; Irina Fierascu; Camelia Ungureanu; Sorin Marius Avramescu; Alina Ortan; Mihaela Ioana Georgescu; Anca Nicoleta Sutan; Anca Zanfirescu; Cristina Elena Dinu-Pirvu; Bruno Stefan Velescu; Valentina Anuta
- Source:
- Food and chemical toxicology 2018 v.111 pp. 44-52
- ISSN:
- 0278-6915
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Allium cepa; Arctium lappa; Aspergillus niger; Penicillium; Veronica persica; aerial parts; anti-inflammatory activity; antioxidant activity; antioxidants; ascorbic acid; bioactive compounds; chromosome aberrations; fungi; high performance liquid chromatography; inflammation; meristems; models; roots; toxicology
- Abstract:
- ... The present study aims to evaluate the potential uses of hydroalcoholic extracts obtained from Romanian native wild-growing plants. The hydroalcoholic extracts were obtained from the burdock roots and respectively the aerial parts of birdeye speedwell. The extracts were characterised by HPLC (quantifying 13 compounds in the V. persica extract, 6 compounds in the A. lappa extract and confirming the ...
- DOI:
- 10.1016/j.fct.2017.11.008
- https://doi.org/10.1016/j.fct.2017.11.008
- Author:
- Petya Dimitrova; Kalina Alipieva; Tsvetinka Grozdanova; Svetlana Simova; Vassya Bankova; Milen I. Georgiev; Milena P. Popova
- Source:
- Food and chemical toxicology 2018 v.111 pp. 605-615
- ISSN:
- 0278-6915
- Subject:
- DNA; NAD ADP-ribosyltransferase; T-lymphocytes; Verbascum; aerial parts; apoptosis; bioactive compounds; bioactive properties; cell cycle checkpoints; cell growth; cell proliferation; colorimetry; concanavalin A; cytokines; flow cytometry; human cell lines; humans; interferon-gamma; interphase; iridoid glycosides; methanol; mice; mitogen-activated protein kinase; phosphorylation; saponins; toxicology
- Abstract:
- ... The Verbascum species are widely used traditional herb remedies against respiratory, inflammatory conditions and disorders. In the present study methanol extract of the aerial parts of the endemic Verbascum nobile Velen, was investigated and two novel iridoid glycosides 1 and 2, together with nine known constituents: iridoids, phenylethanoids, and saponins characteristic of Verbascum genus were id ...
- DOI:
- 10.1016/j.fct.2017.11.060
- https://doi.org/10.1016/j.fct.2017.11.060
- Author:
- Sengul Uysal; Asli Ugurlu; Gokhan Zengin; Mehmet Cengiz Baloglu; Yasemin Celik Altunoglu; Adriano Mollica; Luisa Custodio; Nuno R. Neng; José M.F. Nogueira; M. Fawzi Mahomoodally
- Source:
- Food and chemical toxicology 2018 v.111 pp. 525-536
- ISSN:
- 0278-6915
- Subject:
- Bidens tripartita; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; cell lines; cell viability; chlorogenic acid; computer simulation; cytotoxicity; enzyme inhibition; epicatechin; ethyl acetate; high performance liquid chromatography; hydrogen bonding; methanol; neoplasm cells; neoplasms; plasmids; toxicology; viability assays
- Abstract:
- ... Bidens tripartita L. is a traditional phyto-remedy used in several countries, yet there is still a paucity of data on its biological potential. We aimed to provide new insights on the pharmacological potential of extracts prepared from B. tripartita via highlighting its antioxidant, key enzymes inhibitory potency, and DNA protecting effects. Phytochemical profile was established using High-Perform ...
- DOI:
- 10.1016/j.fct.2017.11.058
- https://doi.org/10.1016/j.fct.2017.11.058
- Author:
- Burcu Guldiken; Gulay Ozkan; Gizem Catalkaya; Fatma Duygu Ceylan; Ipek Ekin Yalcinkaya; Esra Capanoglu
- Source:
- Food and chemical toxicology 2018 v.119 pp. 37-49
- ISSN:
- 0278-6915
- Subject:
- antineoplastic agents; bioactive compounds; chemical constituents of plants; dose response; health promotion; herbs; in vitro studies; infants; neoplasms; pregnant women; risk; spices; toxicology
- Abstract:
- ... Phytochemicals are bioactive plant compounds that can be used as antimicrobial, antibacterial, anticancer agents and are reported to prevent cancer, cardiovascular and inflammatory diseases. Herbs and spices are rich in phytochemicals and can be consumed or used traditionally for medical or dietary purposes since the ancient times. However, there may be serious health risks for some population gro ...
- DOI:
- 10.1016/j.fct.2018.05.050
- https://doi.org/10.1016/j.fct.2018.05.050
- Author:
- Aliye Aras; Sumbul Khalid; Saima Jabeen; Ammad Ahmad Farooqi; Baojun Xu
- Source:
- Food and chemical toxicology 2018 v.119 pp. 206-214
- ISSN:
- 0278-6915
- Subject:
- apoptosis; bioactive compounds; carcinogenesis; clinical trials; disease course; epigenetics; genomics; medicinal properties; microRNA; mothers against decapentaplegic homolog proteins; mushrooms; mutation; neoplasm cells; neoplasms; proteomics; signal transduction; therapeutics; toxicology
- Abstract:
- ... Mushrooms represent a tremendous source of biologically useful and pharmacologically active molecules. Recent breakthroughs in cancer genetics, genomics, proteomics and translational research have helped us to develop a better understanding of the underlying mechanisms which are contributory in cancer development and progression. Different signaling pathways particularly, Wnt, SHH, TGF/SMAD and JA ...
- DOI:
- 10.1016/j.fct.2018.04.038
- https://doi.org/10.1016/j.fct.2018.04.038
- Author:
- Jianbo Xiao
- Source:
- Food and chemical toxicology 2018 v.119 pp. 3-5
- ISSN:
- 0278-6915
- Subject:
- bioactive compounds; bioactive properties; carbon dioxide; catechol; neoplasm cells; new products; polyphenols; pyrogallol; quercetin; toxicology
- Abstract:
- ... We have comprehensively investigated the structure-stability relationship of natural polyphenols in DMEM medium without cells. Polyphenols with catechol or pyrogallol structure were evidently instable in DMEM medium without cells. Herein, we further investigate stability of polyphenols when incubated with cancer cells and its related mechanism. After incubated with SK-28 cells and A549 cells at 37 ...
- DOI:
- 10.1016/j.fct.2018.03.051
- https://doi.org/10.1016/j.fct.2018.03.051
- Author:
- Andrei Mocan; Cadmiel Moldovan; Gökhan Zengin; Onur Bender; Marcello Locatelli; Mario Simirgiotis; Arzu Atalay; Dan Cristian Vodnar; Sascha Rohn; Gianina Crișan
- Source:
- Food and chemical toxicology 2018 v.115 pp. 414-424
- ISSN:
- 0278-6915
- Subject:
- foods; flavonoids; dietary supplements; risk; dose response; toxicology; enzyme inhibition; cultivars; humans; small fruits; cytotoxicity; spermidine; bioactive compounds; antioxidant activity; antioxidants; oxylipins; Lycium barbarum; kidney cells; phenolic acids; healthy diet; functional properties
- Abstract:
- ... Goji (Lycium barbarum L.) berries are emphasized as healthy food or are used widely as dietary supplements. In the present study, the antioxidant and enzyme inhibitory activities of berries extracts from two selected Romanian cultivars (cv. Erma and cv. Biglifeberry) have been evaluated. UHPLC-QTOF-MS analysis results revealed the presence of organic acids, phenolic acids, flavonoids, fatty acids ...
- DOI:
- 10.1016/j.fct.2018.01.054
- https://doi.org/10.1016/j.fct.2018.01.054