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You searched for: Journal Journal of chromatography Remove constraint Journal: Journal of chromatography Subject acidification Remove constraint Subject: acidification Subject term acidification Remove constraint Subject term: acidification Subject term ethyl ether Remove constraint Subject term: ethyl ether
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1. Optimization and validation of direct gas chromatography-mass spectrometry method for simultaneous quantification of ten short-chain fatty acids in rat feces

Author:
Jin-Hao Zhu; Qian Mao; Si-Yu Wang; Hui Liu; Shan-Shan Zhou; Wei Zhang; Ming Kong; He Zhu; Song-Lin Li
Source:
Journal of chromatography 2022 v.1669 pp. 462958
ISSN:
0021-9673
Subject:
acidification; derivatization; ethyl ether; feces; formic acid; gas chromatography-mass spectrometry; rats; temperature; toxicity
Abstract:
... Short-chain fatty acids (SCFAs) play key roles in maintaining health and treating disease. Quantification of important fecal SCFAs is necessary to facilitate the clarification of their biological roles. However, the existing quantifying methods mainly depend on complicated precolumn derivatization, and/or are unable to determine formic acid, a SCFA commonly associated with toxicity. In this study, ...
DOI:
10.1016/j.chroma.2022.462958

2. Development and validation of a GC-FID method for the analysis of short chain fatty acids in rat and human faeces and in fermentation fluids

Author:
Serena Scortichini; Maria Chiara Boarelli; Stefania Silvi; Dennis Fiorini
Source:
Journal of chromatography 2020 v.1143 pp. 121972
ISSN:
1570-0232
Subject:
acetic acid; acidification; chemical species; derivatization; ethyl ether; feces; fermentation; flame ionization; hexanoic acid; humans; intestinal microorganisms; metabolites; mice; polyethylene glycol; propionic acid; quantitative analysis; rats
Abstract:
... Short-chain fatty acids (SCFAs) are gut microbiota metabolites recognized for their beneficial effects on the host organism. In this study, a simple and rapid sample preparation method combined to SCFAs analysis by direct injection and gas chromatography coupled with flame ionization detection (GC-FID), for the determination and quantification of eight SCFAs (acetic, propionic, i-butyric, butyric, ...
DOI:
10.1016/j.jchromb.2020.121972