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You searched for: Journal Journal of ethnopharmacology Remove constraint Journal: Journal of ethnopharmacology Journal name Journal of ethnopharmacology Remove constraint Journal name: Journal of ethnopharmacology Subject Combretum Remove constraint Subject: Combretum Subject Democratic Republic of the Congo Remove constraint Subject: Democratic Republic of the Congo
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1. Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa

Author:
Marianne Molander; Line Nielsen; Søren Søgaard; Dan Staerk; Nina Rønsted; Drissa Diallo; Kusamba Zacharie Chifundera; Johannes van Staden; Anna K. Jäger
Source:
Journal of ethnopharmacology 2014 v.157 pp. 171-180
ISSN:
0378-8741
Subject:
Bauhinia thonningii; Bitis arietans; Combretum; Grewia mollis; Lannea; Naja; Strychnos; active ingredients; antiserum; bioassays; enzyme inhibition; enzyme inhibitors; ethanol; hyaluronoglucosaminidase; inhibitory concentration 50; mortality; necrosis; patients; phospholipase A2; plant anatomy; polyphenols; proteinases; snake bites; snakes; traditional medicine; Democratic Republic of the Congo; Mali; South Africa
Abstract:
... Snakebite envenomation, every year, causes estimated 5–10,000 mortalities and results in more than 5–15,000 amputations in sub-Saharan Africa alone. Antiserum is not easily accessible in these regions or doctors are simply not available, thus more than 80% of all patients seek traditional practitioners as first-choice. Therefore it is important to investigate whether the plants used in traditional ...
DOI:
10.1016/j.jep.2014.09.027

2. Vascular effects and antioxidant activity of two Combretum species from Democratic Republic of Congo

Author:
Francine Nsuadi Manga; Charaf El Khattabi; Jeanine Fontaine; Guy Berkenboom; Pierre Duez; José Lami Nzunzu; Stéphanie Pochet
Source:
Journal of ethnopharmacology 2012 v.142 no.1 pp. 194-200
ISSN:
0378-8741
Subject:
Combretum; antihypertensive effect; antioxidant activity; aorta; bark; endothelium; esters; flavonoids; free radicals; guanylate cyclase; hypertension; indomethacin; leaves; nitric oxide synthase; phenylephrine; plant extracts; prostaglandin synthase; rats; roots; systolic blood pressure; traditional medicine; vasodilation; Democratic Republic of the Congo
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Combretum racemosum P. Beauv (Combretaceae) leaves (CrLv) and root bark (CrRB) and Combretum celastroides subsp. laxiflorum Welw (Combretaceae) leaves (ClLv) are used in Congolese traditional medicine for several therapeutic purposes, notably for the treatment of conditions consistent with hypertension. The present study aims to investigate the vasorelaxant and in v ...
DOI:
10.1016/j.jep.2012.04.039
PubMed:
22564815