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Journal of ethnopharmacology
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- Author:
- Jean Paul Dzoyem; Victor Kuete; Lyndy J. McGaw; Jacobus N. Eloff
- Source:
- Journal of ethnopharmacology 2014 v.156 pp. 1-8
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Adansonia digitata; Aframomum; Mycobacterium aurum; Mycobacterium fortuitum; Mycobacterium smegmatis; Tamarindus indica; antibacterial properties; antioxidant activity; antioxidants; bromides; cytotoxicity; enzyme inhibition; flavonoids; fruits; herbs; infectious diseases; inflammation; inhibitory concentration 50; kidneys; lethal concentration 50; medicinal properties; minimum inhibitory concentration; monkeys; pain; spices; tetrazolium; traditional medicine; Africa
- Abstract:
- ... Culinary herbs and spices are widely used ethnomedically across Africa. They are traditionally employed in the treatment of several ailments including inflammation disorders, pain alleviation and infectious diseases. Pharmacological studies are necessary to provide a scientific basis to substantiate their traditional use and safety. In this study, the 15-lipoxygenase inhibitory, antioxidant, antim ...
- DOI:
- 10.1016/j.jep.2014.08.007
- https://doi.org/10.1016/j.jep.2014.08.007
- Author:
- Qinxiao Guan; Shengwang Liang; Zhanhong Wang; Yongxia Yang; Shumei Wang
- Source:
- Journal of ethnopharmacology 2014 v.154 no.1 pp. 65-75
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; amino acids; apoptosis; biochemical pathways; brain; cerebrovascular disorders; death; emodin; energy; histopathology; infarction; ingredients; ischemia; metabolomics; models; neurons; nuclear magnetic resonance spectroscopy; pharmacodynamics; principal component analysis; protective effect; rats; rhubarb; society; urine
- Abstract:
- ... The ischemia cerebrovascular disease is one of leading causes of death and long-term disability in modern society. Rhubarb is one of the common traditional Chinese medicine with many effects, and the main pharmacodynamic ingredients are aloe-emodin, rhein, emodin, chrysophanol and physcion. The five components are also known as rhubarb aglycone. Rhubarb aglycone has been confirmed to play a remark ...
- DOI:
- 10.1016/j.jep.2014.03.002
- https://doi.org/10.1016/j.jep.2014.03.002
- Author:
- Jong Rhan Kim; Jinhwan Choi; Jiyoung Kim; Heejeung Kim; Heerim Kang; Eun Hye Kim; Jeong-Hwa Chang; Yeong-Eun Kim; Young Jin Choi; Ki Won Lee; Hyong Joo Lee
- Source:
- Journal of ethnopharmacology 2014 v.151 no.1 pp. 365-371
- ISSN:
- 0378-8741
- Subject:
- ginsenosides; immunomodulators; plant extracts; oral administration; metabolites; Dermatophagoides farinae; chemokine CCL22; skin lesions; ears; monoclonal antibodies; splenocytes; traditional medicine; blood serum; histology; anti-allergic agents; mice; Panax; eosinophils; atopic dermatitis; mast cells
- Abstract:
- ... Ginseng and ginsenosides are frequently used in the treatment of chronic inflammatory diseases. Recently, 20-O-β-d-glucopyranosyl-20(S)-protopanaxadiol (GPD), the main metabolite of ginsenosides, was reported to have both anti-allergic and anti-pruritic effects. The immunomodulatory effects of GPD-fortified ginseng extract (GFGE) on atopic dermatitis (AD)-like symptoms in mice were investigated. T ...
- DOI:
- 10.1016/j.jep.2013.10.058
- https://doi.org/10.1016/j.jep.2013.10.058
- Author:
- Yanyan Yang; Woo Seok Yang; Tao Yu; Gi-Ho Sung; Kye Won Park; Keejung Yoon; Young-Jin Son; Hyunsik Hwang; Yi-Seong Kwak; Chang-Muk Lee; Man Hee Rhee; Jong-Hoon Kim; Jae Youl Cho
- Source:
- Journal of ethnopharmacology 2014 v.154 no.1 pp. 218-228
- ISSN:
- 0378-8741
- Subject:
- Panax ginseng; anti-inflammatory activity; apoptosis; cyclic AMP; gastritis; herbal medicines; inducible nitric oxide synthase; inflammation; interferon regulatory factor-3; interferons; lipopolysaccharides; luciferase; messenger RNA; mice; mitogen-activated protein kinase; models; nitric oxide; peritonitis; prostaglandin synthase; traditional medicine; Korean Peninsula
- Abstract:
- ... Korean Red Ginseng (KRG) is one of the representative traditional herbal medicines prepared from Panax ginseng Meyer (Araliaceae) in Korea. It has been reported that KRG exhibits a lot of different biological actions such as anti-aging, anti-fatigue, anti-stress, anti-atherosclerosis, anti-diabetic, anti-cancer, and anti-inflammatory activities. Although systematic studies have investigated how KR ...
- DOI:
- 10.1016/j.jep.2014.04.008
- https://doi.org/10.1016/j.jep.2014.04.008
- Author:
- Lian-Wu Xie; Atanas G. Atanasov; De-An Guo; Clemens Malainer; Jing-Xian Zhang; Martin Zehl; Shu-Hong Guan; Elke H. Heiss; Ernst Urban; Verena M. Dirsch; Brigitte Kopp
- Source:
- Journal of ethnopharmacology 2014 v.152 no.3 pp. 470-477
- ISSN:
- 0378-8741
- Subject:
- Lycium chinense; Oriental traditional medicine; active ingredients; agonists; amides; antagonists; bark; cortex; diabetes mellitus; ethyl acetate; fractionation; genes; inflammation; inhibitory concentration 50; mechanism of action; methanol; methylene chloride; moieties; nuclear magnetic resonance spectroscopy; palmitic acid; peroxisome proliferator-activated receptors; structure-activity relationships; transcription (genetics); transcription factor NF-kappa B; tumor necrosis factor-alpha; tyramine
- Abstract:
- ... The root bark of Lycium chinense Miller, Lycii Radicis Cortex, has been used in traditional Chinese medicine (TCM) to treat different inflammation-related symptoms, such as diabetes mellitus. The pro-inflammatory transcription factor nuclear factor kappa B (NF-κB) is a key regulator of inflammation, while the transcription factor peroxisome proliferator-activated receptor gamma (PPARγ) is a key mo ...
- DOI:
- 10.1016/j.jep.2014.01.029
- https://doi.org/10.1016/j.jep.2014.01.029
- Author:
- Lili Wang; Zhiqiang Li; Lin Li; Yanlin Li; Meng Yu; Yunfeng Zhou; Xinyong Lv; Hiderori Arai; Yang Xu
- Source:
- Journal of ethnopharmacology 2014 v.158 pp. 207-215
- ISSN:
- 0378-8741
- Subject:
- acute toxicity; adults; adverse effects; alanine transaminase; albumins; alkaline phosphatase; body weight; cholesterol; cortex; cough; glucose; hematopoiesis; histology; jaundice; kidneys; liver; liver function; lymphocytes; mice; mortality; oral administration; rats; rheumatoid arthritis; skin diseases; toxicity testing; traditional medicine; urea nitrogen
- Abstract:
- ... Cortex Dictamni is used in Chinese folk medicine for the treatment of jaundice, cough, rheumatism and some skin diseases; however, its possible toxicity has not been rigorously studied. The present investigation was carried out to evaluate the safety of Cortex Dictamni aqueous extract (CDAE) by acute and sub-chronic toxicity studies.In acute toxicity tests, seven groups of mice (n=5/group/sex) wer ...
- DOI:
- 10.1016/j.jep.2014.10.027
- https://doi.org/10.1016/j.jep.2014.10.027
- Author:
- Maxwell I. Ezeja; Aruh O. Anaga; Isaac U. Asuzu
- Source:
- Journal of ethnopharmacology 2014 v.151 pp. 1155-1164
- ISSN:
- 0378-8741
- Subject:
- Gouania; acute toxicity; antioxidant activity; blood sampling; blood serum; cholesterol; death; diabetes mellitus; dose response; edema; eyes; heart; heart diseases; hematologic tests; high density lipoprotein; histopathology; kidneys; leaf extracts; leaves; lipid peroxidation; liver; lungs; malaria; methanol; morbidity; oral administration; rats; superoxide dismutase; toxicity testing; traditional medicine; triacylglycerols; urea; very low density lipoprotein; Africa
- Abstract:
- ... Gouania longipetala leaves are commonly used in folkloric medicine in Africa and other parts of the world for treatment of edema, febrifuges, veneral diseases, lumbago, heart diseases, diabetes mellitus malaria, etc. This study therefore evaluated safety profile of the methanol leaf extract of the plant using acute and sub-chronic studies in rat model.Acute toxicity test of the plant lasted for 48 ...
- DOI:
- 10.1016/j.jep.2013.12.034
- https://doi.org/10.1016/j.jep.2013.12.034
- Author:
- Hwayong Park; Youn-Hwan Hwang; Hye Jin Yang; Hyun-Kyu Kim; Kyung Seuk Song; Jin Yeul Ma
- Source:
- Journal of ethnopharmacology 2014 v.156 pp. 182-189
- ISSN:
- 0378-8741
- Subject:
- Chinese hamsters; Escherichia; Salmonella; acute toxicity; animal ovaries; bacteria; body weight changes; chromosome aberrations; dietary exposure; freeze drying; genotoxicity; glycyrrhizin; health services; herbs; ingredients; laboratory animals; liquid chromatography; mice; micronucleus tests; mutation; rats; signs and symptoms (animals and humans); therapeutics; traditional medicine; East Asia
- Abstract:
- ... Guibi-tang (Guipi-tang in Chinese and Kihi-to in Japanese) is a multi-herb traditional medicine commonly prescribed to treat psychoneurosis in East Asia. Although this medicine has been widely used, there is little available information on the safety and toxicity of Guibi-tang, especially on the fermented one.Guibi-tang, composed of 12 herbs, was fermented with bacteria and lyophilized. Single dos ...
- DOI:
- 10.1016/j.jep.2014.09.004
- https://doi.org/10.1016/j.jep.2014.09.004
- Author:
- J. Luka; S.J. Badau; A.W. Mbaya; J.J. Gadzama; H.A. Kumshe
- Source:
- Journal of ethnopharmacology 2014 v.153 no.1 pp. 268-273
- ISSN:
- 0378-8741
- Subject:
- Diospyros mespiliformis; acute toxicity; antimalarials; blood serum; body weight changes; death; enzymes; erythrocytes; hematocrit; hematology; hemoglobin; lethal dose 50; leukocytes; local government; rats; roots; toxicity testing; traditional medicine; Nigeria
- Abstract:
- ... Different parts of the plant Diospyros mespiliformis have been used traditionally for the treatment of ailments in Nigeria particularly among the Kamwe people of Michika local government area of Adamawa State where the root has been used as an anti-malarial for ages. Most of the uses have been without any scientific evidence and toxicological assessment. The present study aimed to determine acute ...
- DOI:
- 10.1016/j.jep.2014.02.033
- https://doi.org/10.1016/j.jep.2014.02.033
- Author:
- Jing Li; Guoyong Yu; Junfeng Fan
- Source:
- Journal of ethnopharmacology 2014 v.155 no.1 pp. 285-292
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Sorghum (Poaceae); active sites; adenosine diphosphate; arachidonic acid; aspirin; blood; cardiovascular diseases; collagen; glucosides; mandelic acid; metabolism; monosaccharides; platelet aggregation; prostaglandin synthase; sorbitol; thrombin; vinegars; xylitol
- Abstract:
- ... Vinegar has been used as both a common seasoning and a traditional Chinese medicine. Sorghum vinegar is an excellent source of physiological substances with multiple health benefits.To evaluate the antiplatelet aggregation activity of alditols and monosaccharides extracted from sorghum vinegar and analysis its mechanism.Alditol and monosaccharide extract (AME) from sorghum vinegar was first evalua ...
- DOI:
- 10.1016/j.jep.2014.05.018
- https://doi.org/10.1016/j.jep.2014.05.018
- Author:
- Mahendra S. Khyade; Deepak M. Kasote; Nityanand P. Vaikos
- Source:
- Journal of ethnopharmacology 2014 v.153 no.1 pp. 1-18
- ISSN:
- 0378-8741
- Subject:
- Alstonia macrophylla; Alstonia scholaris; adulterated products; alkaloids; antineoplastic activity; aphrodisiacs; gastrointestinal system; jaundice; malaria; medicinal plants; metabolic studies; neoplasms; plant biochemistry; therapeutics; toxicity; traditional medicine; India; Malaysia; Philippines; Thailand
- Abstract:
- ... Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don are two vital medicinal plant species (family: Apocynaceae). In India, the therapeutic use of Alstonia scholaris has been described in both codified and non-codified drug systems for the treatment of malaria, jaundice, gastrointestinal troubles, cancer and in many other ailments. Other species, Alstonia macrophylla has been us ...
- DOI:
- 10.1016/j.jep.2014.01.025
- https://doi.org/10.1016/j.jep.2014.01.025
- Author:
- Edwin Ogechukwu Omeje; Mohd Parvez Khan; Patience Ogoamaka Osadebe; Deepshikha Tewari; Mohammad Faheem Khan; Kapil Dev; Rakesh Maurya; Naibedya Chattopadhyay
- Source:
- Journal of ethnopharmacology 2014 v.151 no.1 pp. 643-651
- ISSN:
- 0378-8741
- Subject:
- Bombax; Citrus; Cola nitida; Garcinia kola; Loranthus; adults; alkaline phosphatase; antineoplastic activity; bark; bone formation; bone morphogenetic proteins; cytotoxicity; diabetes; disease control; females; gene expression; genes; hosts; hypoglycemic agents; leaves; lupeol; mineralization; models; neonates; osteoblasts; osteoporosis; pain; palmitates; postmenopause; quercetin; rats; skull; therapeutics; traditional medicine; transcription (genetics); transcription factors; viability; Nigeria
- Abstract:
- ... Mistletoe extracts (decoctions) are used traditionally in eastern Nigeria for the management of bone pain, post menopausal syndrome and diabetes amongst several other ailments. While scientific evidence supporting its folkloric use as an antidiabetic agent has been documented, the age-long practice of its use in treatment of post menopausal syndrome has not been scientifically validated. Postmenop ...
- DOI:
- 10.1016/j.jep.2013.11.029
- https://doi.org/10.1016/j.jep.2013.11.029
- Author:
- Xiao-fen Zheng; Jun-sheng Tian; Peng Liu; Jie Xing; Xue-mei Qin
- Source:
- Journal of ethnopharmacology 2014 v.151 no.2 pp. 912-920
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; animal models; biochemical pathways; biomarkers; body weight; diarrhea; drugs; energy; feces; glycolysis; lactic acid; leucine; liver; males; metabolites; metabolomics; nuclear magnetic resonance spectroscopy; oral administration; rats; spleen; starvation; swimming; uterine prolapse; valine
- Abstract:
- ... Bu-zhong-yi-qi-tang (BT) is a classical formula for the treatment of spleen-qi descending, visceroptosis with hyposplenic qi, uterine prolapse, and rectal prolapse due to chronic diarrhea in traditional Chinese medicine (TCM) and has been identified as an effective drug for the treatment of TCM spleen-qi deficiency in clinical practice. The present study aimed to investigate the restorative effect ...
- DOI:
- 10.1016/j.jep.2013.12.001
- https://doi.org/10.1016/j.jep.2013.12.001
- Author:
- Hyun Kim; Mi-Jang Song
- Source:
- Journal of ethnopharmacology 2014 v.153 no.1 pp. 85-89
- ISSN:
- 0378-8741
- Subject:
- Araliaceae; Asteraceae; Fabaceae; Pinaceae; Poaceae; Rosaceae; diabetes; indigenous knowledge; interviews; medicinal plants; national parks; nervous system diseases; pain; questionnaires; respiratory tract diseases; social networks; traditional medicine; Korean Peninsula
- Abstract:
- ... The purpose of this study is to analyze and record traditional knowledge of medicinal plants utilized in communities of Jirisan National Park.Data was collected through participant observations and in-depth interviews with semi-structured questionnaires. Quantitative comparative analyses were accomplished through informant consensus factor (ICF), fidelity level (FL), and social network analysis (S ...
- DOI:
- 10.1016/j.jep.2013.10.047
- https://doi.org/10.1016/j.jep.2013.10.047
- Author:
- Hyun Kim; Mi-Jang Song
- Source:
- Journal of ethnopharmacology 2014 v.153 no.1 pp. 90-97
- ISSN:
- 0378-8741
- Subject:
- Hymenochaetaceae; Pleurotaceae; Polyporaceae; Tricholomataceae; cardiovascular diseases; diabetes; indigenous knowledge; interviews; medicinal fungi; national parks; questionnaires; soups; traditional medicine; wild edible mushrooms; Korean Peninsula
- Abstract:
- ... This study aims to record and analyze the traditional knowledge of wild edible mushrooms utilized by residents living in Jirisan National Park (Korea).Data was collected through participant observations and in-depth interviews with semi-structured questionnaires. Quantitative comparative analyses were accomplished through informant consensus factor (ICF), fidelity level (FL), and inter-network ana ...
- DOI:
- 10.1016/j.jep.2013.12.041
- https://doi.org/10.1016/j.jep.2013.12.041
- Author:
- A.B. Seres; E. Ducza; M. Báthori; A. Hunyadi; Z. Béni; M. Dékány; J. Hajagos-Tóth; J. Verli; Róbert Gáspár
- Source:
- Journal of ethnopharmacology 2014 v.153 no.2 pp. 446-453
- ISSN:
- 0378-8741
- Subject:
- Apis mellifera; Western blotting; active ingredients; fractionation; gas chromatography-mass spectrometry; honey bees; male fertility; males; men; messenger RNA; milk; nuclear magnetic resonance spectroscopy; oleic acid; palmitates; protein content; protein synthesis; quantitative polymerase chain reaction; rats; spectral analysis; testosterone; therapeutics; tissues; traditional medicine; women
- Abstract:
- ... Numerous honeybee (Apis mellifera) products have been used in traditional medicine to treat infertility and to increase vitality in both men and women. Drone milk (DM) is a relatively little-known honeybee product with a putative sexual hormone effect. The oestrogenic effect of a fraction of DM has recently been reported in rats. However, no information is available on the androgenic effects of DM ...
- DOI:
- 10.1016/j.jep.2014.02.050
- https://doi.org/10.1016/j.jep.2014.02.050
- Author:
- Hyun-Soo Shin; Jong-Min Han; Hyeong-Geug Kim; Min-Kyung Choi; Chang-Gue Son; Ho-Ryong Yoo; Hyun-Kyung Jo; In-Chan Seol
- Source:
- Journal of ethnopharmacology 2014 v.153 no.1 pp. 142-150
- ISSN:
- 0378-8741
- Subject:
- Artemisia; Curcuma longa; Western diets; aorta; atherosclerosis; blood lipids; blood serum; cholesterol; curcumin; fatty liver; gene expression; glucose; high density lipoprotein; hyperlipidemia; interleukin-1beta; interleukin-6; lipid composition; low density lipoprotein; mice; reactive oxygen species; tissues; traditional medicine; triacylglycerols; tumor necrosis factor-alpha
- Abstract:
- ... Artemisiaiwayomogi Kitamura and Curcuma longa Linne. (ACE) has been popularly used to treat atherosclerosis as well as hyperlipidemia in the Asian countries.Antiatherosclerotic and anti-hyperlipidemic effects of ACE were evaluated at protein and gene expression level by using apoE⁻/⁻ mice.Apoprotein E deficient (apoE⁻/⁻) mice were randomly divided into five groups and fed freely Western diet (WD) ...
- DOI:
- 10.1016/j.jep.2014.01.039
- https://doi.org/10.1016/j.jep.2014.01.039
- Author:
- Ratul Sarkar; Sushil K. Chaudhary; Amrita Sharma; Kirendra K. Yadav; Neelesh K. Nema; Mamello Sekhoacha; Sanmoy Karmakar; Fernão C. Braga; Motlalepula Gilbert Matsabisa; Pulok K. Mukherjee; Tuhinadri Sen
- Source:
- Journal of ethnopharmacology 2014 v.154 no.1 pp. 170-175
- ISSN:
- 0378-8741
- Subject:
- Pseudomonas aeruginosa; Sclerocarya birrea subsp. caffra; alcoholic beverages; antibiotic resistance; antimicrobial properties; bacterial motility; bark; biofilm; dysentery; ethnobotany; fruits; gentian violet; methanol; microbial growth; proteinases; pyoverdines; quorum sensing; secretion; socioeconomics; swarming; traditional medicine; virulence; Africa
- Abstract:
- ... Marula (Sclerocarya birrea; family – Anacardiaceae) is an African plant, which enjoys wide socio-economic importance particularly in southern part of Africa. The fruits are consumed as food and also as alcoholic beverage (cream liquor). In different parts of Africa, the decoction of the bark is traditionally used for the treatment of dysentery, diarrhoea, and various other infectious conditions. T ...
- DOI:
- 10.1016/j.jep.2014.03.067
- https://doi.org/10.1016/j.jep.2014.03.067
- Author:
- Muhammad Munawar Hayat; Sadia Sarwar; Shazia Anjum; Muhammad Uzair; Hafiz Muhammad Farhan Rasheed; Qaiser Jabeen; Bashir Ahmad Choudhary; Muhammad Ashraf
- Source:
- Journal of ethnopharmacology 2014 v.156 pp. 347-352
- ISSN:
- 0378-8741
- Subject:
- rabbits; alloxan; Brassicaceae; median effective concentration; acetylcholinesterase; diarrhea; glibenclamide; jejunum; enzyme inhibition; tissues; animal disease models; traditional medicine; linoleate 13S-lipoxygenase; blood glucose; glycemic effect; potassium; phosphodiesterase I; diabetes; antioxidant activity; enzyme activity; rats; parasympatholytics; methanol; therapeutics; fever
- Abstract:
- ... Folk herbal practitioners of the Cholistan desert claim Farsetia hamiltonii Royle (Brassicaceae) to treat diabetes, oxidative damages, diarrhea, fever, and abdominal cramps. The aim of this study was to scientifically find the potential of Farsetia hamiltonii in treating diabetes and gastrointestinal diseases.In vivo anti-diabetic activity of Farsetia hamiltonii was studied on alloxan induced diab ...
- DOI:
- 10.1016/j.jep.2014.08.038
- https://doi.org/10.1016/j.jep.2014.08.038
- Author:
- Mohammed Auwal Ibrahim; M. Shahidul Islam
- Source:
- Journal of ethnopharmacology 2014 v.153 no.2 pp. 392-399
- ISSN:
- 0378-8741
- Subject:
- acetone; alanine transaminase; alkaline phosphatase; alpha-amylase; alpha-glucosidase; animal disease models; bark; blood glucose; blood lipids; blood serum; body weight; enzyme inhibition; ethyl acetate; glucose tolerance; glycemic effect; glycogen; in vivo studies; insulin; insulin resistance; islets of Langerhans; liver; males; noninsulin-dependent diabetes mellitus; oral administration; rats; solvents; traditional medicine; urea; Nigeria
- Abstract:
- ... Senna singueana is currently used in the traditional treatment of diabetes mellitus in Nigeria. The present study examined the anti-diabetic activity of the Senna singueana acetone fraction (SSAF) of stem bark in a type 2 diabetes (T2D) rat model.Crude ethyl acetate extract of the Senna singueana stem bark was fractionated with various solvents and the acetone fraction was selected for in vivo stu ...
- DOI:
- 10.1016/j.jep.2014.02.042
- https://doi.org/10.1016/j.jep.2014.02.042
- Author:
- Shuli Man; Wei Fan; Wenyuan Gao; Yuanyuan Li; Yan Wang; Zhen Liu; Hongfa Li
- Source:
- Journal of ethnopharmacology 2014 v.151 no.1 pp. 407-412
- ISSN:
- 0378-8741
- Subject:
- DNA fragmentation; Oriental traditional medicine; antioxidants; blood serum; diethylnitrosamine; lipid peroxidation; liver; liver diseases; metabolomics; nuclear magnetic resonance spectroscopy; oxidative stress; rats; saponins; tricarboxylic acid cycle; urine
- Abstract:
- ... Paris polyphylla var. yunnanensis as a traditional Chinese medicine has been used in the treatment of liver disease for thousands of years. Rhizoma paridis saponins (RPS), as the main active components of Paris polyphylla, have been used to treat liver injury. Anti-cirrhosis effect of Rhizoma paridis saponins (RPS) has not been known.We analyzed diethylnitrosamine (DEN)-induced metabonomic changes ...
- DOI:
- 10.1016/j.jep.2013.10.051
- https://doi.org/10.1016/j.jep.2013.10.051
- Author:
- Fabio R.M. Borges; Morgana D. Silva; Marina M. Córdova; Tiago R. Schambach; Moacir G. Pizzolatti; Adair R.S. Santos
- Source:
- Journal of ethnopharmacology 2014 v.151 no.1 pp. 144-150
- ISSN:
- 0378-8741
- Subject:
- Polygala; aerial parts; anesthetics; anti-inflammatory activity; dexamethasone; inflammation; interleukin-10; interleukin-1beta; interleukin-6; intraperitoneal injection; kidneys; lipopolysaccharides; methylene chloride; mice; models; neutrophils; peritonitis; therapeutics; traditional medicine; tumor necrosis factor-alpha; Brazil
- Abstract:
- ... Polygala sabulosa A. W. Bennett is a small herb popularly known as “timutu-pinheirinho” that is widely distributed in southern Brazil and that is used to treat disorders of the bowel and kidney and as a topical anesthetic and expectorant in folk medicine. This study was designed to investigate the anti-inflammatory properties of the hydroalcoholic extract (HEPs), CH2Cl2 fraction and the steroid α- ...
- DOI:
- 10.1016/j.jep.2013.10.009
- https://doi.org/10.1016/j.jep.2013.10.009
- Author:
- Guillermo Schmeda-Hirschmann; Carla Delporte; Gabriela Valenzuela-Barra; Ximena Silva; Gabriel Vargas-Arana; Beatriz Lima; Gabriela E. Feresin
- Source:
- Journal of ethnopharmacology 2014 v.156 pp. 9-15
- ISSN:
- 0378-8741
- Subject:
- Boa constrictor; Chelonoidis; Electrophorus electricus; Escherichia coli; Geochelone; Inia geoffrensis; Melanosuchus niger; Salmonella Enteritidis; Staphylococcus aureus; animal fats and oils; anti-inflammatory activity; anti-inflammatory agents; antimicrobial properties; arachidonic acid; conservation status; dolphins; ears; edema; esters; fish; gas chromatography-mass spectrometry; linoleic acid; markets; mice; minimum inhibitory concentration; oleic acid; palmitic acid; reptiles; traditional medicine; Amazonia; Peru
- Abstract:
- ... Animal oils and fats from the fishes Electrophorus electricus and Potamotrygon motoro, the reptiles Boa constrictor, Chelonoidis denticulata (Geochelone denticulata) and Melanosuchus niger and the riverine dolphin Inia geoffrensis are used as anti-inflammatory agents in the Peruvian Amazon. The aim of the study was to assess the topic anti-inflammatory effect of the oils/fats as well as to evaluat ...
- DOI:
- 10.1016/j.jep.2014.08.010
- https://doi.org/10.1016/j.jep.2014.08.010
- Author:
- K.D.K.P. Kumari; T.C.S. Weerakoon; S.M. Handunnetti; K. Samarasinghe; T.S. Suresh
- Source:
- Journal of ethnopharmacology 2014 v.151 pp. 1202-1208
- ISSN:
- 0378-8741
- Subject:
- Aegle marmelos; anti-inflammatory activity; antioxidant activity; antioxidants; beverages; carrageenan; dose response; edema; erythrocytes; flowers; histamine; lipid peroxidation; nitric oxide; rats; rural areas; traditional medicine; trees; Asia
- Abstract:
- ... Almost all part of the plant Aegle marmelos (Bael tree) has been used in the traditional medicine systems of Asian countries to treat various diseases over many centuries. The water extract of the dried flowers of Aegle marmelos is a commonly used beverage among Sri Lankan population in rural areas. Although extensive investigations done on many parts of the plant there are no experimental data av ...
- DOI:
- 10.1016/j.jep.2013.12.043
- https://doi.org/10.1016/j.jep.2013.12.043
- Author:
- Ling Tong; Tu Chen; Zhenzhong Chen; Peng Zhang; Huifang Pi; Hanli Ruan; Jizhou Wu
- Source:
- Journal of ethnopharmacology 2014 v.155 no.3 pp. 1553-1560
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Western blotting; anti-inflammatory activity; dose response; ears; edema; enzyme activity; ethanol; ethyl acetate; inducible nitric oxide synthase; inflammation; interleukin-6; lipopolysaccharides; macrophages; nitric oxide; prostaglandin synthase; rheumatoid arthritis; secretion; transcription (genetics); transcription factor NF-kappa B; tumor necrosis factor-alpha; xylene
- Abstract:
- ... Radix Toddaliae Asiaticae has long been used as a traditional ethnic Chinese medicine for the treatment of inflammation and rheumatism. In our earlier communication we have reported the anti-arthritic activity of the ethyl alcohol extract and ethyl acetate fraction from Radix Toddaliae Asiaticae. This study was to examine the anti-inflammatory activity of prenylcoumarin omphalocarpin isolated from ...
- DOI:
- 10.1016/j.jep.2014.07.055
- https://doi.org/10.1016/j.jep.2014.07.055
- Author:
- Qianqian Xu; Yubo Wang; Shijin Guo; Zhiqiang Shen; Yanping Wang; Limei Yang
- Source:
- Journal of ethnopharmacology 2014 v.152 no.3 pp. 540-545
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Populus canadensis; Populus tomentosa; analgesic effect; analgesics; anti-inflammatory activity; arachidonic acid; carrageenan; cotton; diarrhea; dose response; ears; edema; formalin; granuloma; hot plate test; males; pain; writhing test; East Asia
- Abstract:
- ... Flos populi is an important traditional Chinese medicine prepared from the male inflorescence of Populus tomentosa Carr. or Populus canadensis Moench (Salicaceae family). Flos populi is mainly used for the treatment of various inflammatory diseases and anti diarrhea in East Asian countries. The objective of this study was to investigate the anti-inflammatory and analgesic properties of the aqueous ...
- DOI:
- 10.1016/j.jep.2014.01.037
- https://doi.org/10.1016/j.jep.2014.01.037
- Author:
- Nicole Anzanelo Meira; Luiz Carlos Klein Jr; Lilian W. Rocha; Zhelmy Martin Quintal; Franco Delle Monache; Valdir Cechinel Filho; Nara Lins Meira Quintão
- Source:
- Journal of ethnopharmacology 2014 v.151 no.2 pp. 975-983
- ISSN:
- 0378-8741
- Subject:
- Chrysophyllum cainito; acetates; adverse effects; anti-inflammatory activity; chemical constituents of plants; chloroform; diabetes mellitus; edema; hypersensitivity; interleukin-1beta; leaves; locomotion; mice; myeloperoxidase; neutrophils; pain; thin layer chromatography; traditional medicine; trees; triterpenoids; tumor necrosis factor-alpha
- Abstract:
- ... Chrysophyllum cainito, popularly known as “star apple”, caimito, “abiu-roxo” or “abiu-do-Pará”, is a tree of about 25m in height. Besides its culinary use, it is also used in folk medicine for the treatment of diabetes mellitus and several inflammatory diseases.The crude methanolic extract (CME) was submitted to phytochemical studies for obtaining fractions and isolated compounds. They were monito ...
- DOI:
- 10.1016/j.jep.2013.12.014
- https://doi.org/10.1016/j.jep.2013.12.014
- Author:
- Minjung Song; Hye-Jin Park
- Source:
- Journal of ethnopharmacology 2014 v.154 no.2 pp. 311-318
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Phellinus linteus; Western blotting; animal models; anti-inflammatory activity; antineoplastic activity; brown rice; colitis; colon; dextran; filtration; gamma-aminobutyric acid; inducible nitric oxide synthase; inflammation; lipopolysaccharides; macrophages; mice; mitogen-activated protein kinase; neoplasms; nitric oxide; prostaglandin synthase; prostaglandins; sodium; sulfasalazine; transcription factor NF-kappa B; tumor necrosis factor-alpha
- Abstract:
- ... Phellinus linteus is a herb used in traditional Asian medicine to treat stomachache, inflammation, and tumors. Recent studies show that the extract of Phellinus linteus has anti-inflammatory and antitumor activities. However, Phellinus linteus extract has limitation of high cost and limited availability because of supply shortage. Here, we grew Phellinus linteus on germinated brown rice to address ...
- DOI:
- 10.1016/j.jep.2013.12.059
- https://doi.org/10.1016/j.jep.2013.12.059
- Author:
- Ji-Sun Shin; Eu-Jin Cho; Hye-Eun Choi; Ji-Hyung Seo; Hyo-Jin An; Hee-Juhn Park; Young-Wuk Cho; Kyung-Tae Lee
- Source:
- Journal of ethnopharmacology 2014 v.158 pp. 291-300
- ISSN:
- 0378-8741
- Subject:
- Rubus coreanus; Rubus occidentalis; animal models; anti-inflammatory activity; asthma; body weight; colitis; colon; cytokines; dextran; diarrhea; epithelium; feces; hemorrhage; immunoassays; immunohistochemistry; lipopolysaccharides; luciferase; macrophage activation; macrophages; mechanism of action; mice; mitogen-activated protein kinase; neoplasms; nitric oxide; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signal transduction; sodium; stomach; therapeutics; traditional medicine; transcription factor NF-kappa B; triterpenoids
- Abstract:
- ... Rubus coreanus Miquel (Rosaceae), the Korean black raspberry, has traditionally been used to treat inflammatory diseases including diarrhea, asthma, stomach ailment, and cancer. Although previous studies showed that the 19α-hydroxyursane-type triterpenoids isolated from Rubus coreanus exerted anti-inflammatory activities, their effects on ulcerative colitis and mode of action have not been explore ...
- DOI:
- 10.1016/j.jep.2014.10.044
- https://doi.org/10.1016/j.jep.2014.10.044
- Author:
- Kai Wang; Jianglin Zhang; Shun Ping; Quanxin Ma; Xuan Chen; Hongzhuan Xuan; Jinhu Shi; Cuiping Zhang; Fuliang Hu
- Source:
- Journal of ethnopharmacology 2014 v.155 no.1 pp. 300-311
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Populus canadensis; anti-inflammatory activity; antioxidant activity; buds; endotoxemia; ethanol; flavonoids; high performance liquid chromatography; histopathology; interleukin-10; interleukin-12; interleukin-1beta; interleukin-6; lungs; messenger RNA; propolis; protective effect; reporter genes; secretion; therapeutics; traditional medicine; tumor necrosis factor-alpha
- Abstract:
- ... Propolis is used widely in a number of cultures as a folk medicine and is gaining wider recognition for its potential therapeutic use, due to its wide range of biological properties and pharmacological activities, especially its anti-inflammatory effects. Despite an increasing number of studies focused on the biological activities of propolis together with its botanical sources, studies on Chinese ...
- DOI:
- 10.1016/j.jep.2014.05.037
- https://doi.org/10.1016/j.jep.2014.05.037
- Author:
- Hyun-A. Oh; Hyuck Jai Choi; Nam Jae Kim; Dong-Hyun Kim
- Source:
- Journal of ethnopharmacology 2014 v.153 no.3 pp. 928-932
- ISSN:
- 0378-8741
- Subject:
- Astragalus membranaceus; antagonists; anti-inflammatory activity; anxiety; astragalosides; blood serum; corticosterone; enzyme-linked immunosorbent assay; ethanol; immunomodulation; inflammation; interleukin-6; mice; oral administration; roots; traditional medicine; tranquilizers; tumor necrosis factor-alpha
- Abstract:
- ... Astragaloside IV, a major component extracted from the roots of Astragalus membranaceus (AM), possesses anti-inflammatory, anti-oxidative, anti-fibrotic, anti-infarction and immunoregulatory effects. To clarify anti-stress effect of AM, anxiolytic and anti-inflammatory effects of 80% ethanol extract of AM and astragaloside IV were investigated in immobilization stress model.The mice were orally ad ...
- DOI:
- 10.1016/j.jep.2014.03.068
- https://doi.org/10.1016/j.jep.2014.03.068
- Author:
- Mohammed Auwal Ibrahim; Aminu Mohammed; Murtala Bindawa Isah; Abubakar Babando Aliyu
- Source:
- Journal of ethnopharmacology 2014 v.154 no.1 pp. 26-54
- ISSN:
- 0378-8741
- Subject:
- African trypanosomiasis; antitrypanosomal properties; clinical trials; in vivo studies; livestock; medicinal plants; traditional medicine; tropical diseases
- Abstract:
- ... African trypanosomiasis is one of the neglected tropical diseases caused by different species of trypanosomes that affect both human and livestock with devastating consequences in the continent. Most of the affected populations commonly use traditional medicinal plants for the treatment of the disease. Consequently, this prompted ethnopharmacological research activities on the anti-trypanosomal ac ...
- DOI:
- 10.1016/j.jep.2014.04.012
- https://doi.org/10.1016/j.jep.2014.04.012
- Author:
- Bengui Ye; Jun Li; Zu Li; Jinrong Yang; Ting Niu; Shu Wang
- Source:
- Journal of ethnopharmacology 2014 v.153 no.1 pp. 258-267
- ISSN:
- 0378-8741
- Subject:
- Marsdenia tenacissima; Western blotting; antineoplastic activity; apoptosis; asthma; caspase-3; caspase-9; cell cycle; cough; cyclins; cytotoxicity; esophageal neoplasms; genes; hepatoma; immunohistochemistry; lung neoplasms; medicinal plants; models; mononuclear leukocytes; neoplasm cells; staining; stomach neoplasms; traditional medicine; China
- Abstract:
- ... Marsdenia tenacissima, a traditional Chinese medicinal herb, endemic to Yunnan Province is widely used to treat cough, asthma, expectorant, esophageal cancer, gastric cancer, lung cancer, and hepatocellular carcinoma. The aim of this study was to evaluate in vitro and in vivo anti-hematologic neoplasm potential of the ethanolic extract of this herb (crude ethanolic extract of Marsdenia tenacissima ...
- DOI:
- 10.1016/j.jep.2014.02.035
- https://doi.org/10.1016/j.jep.2014.02.035
- Author:
- Hong-Xiang Sun; Li-Qing Chen; Juan Zhang; Feng-Yang Chen
- Source:
- Journal of ethnopharmacology 2014 v.153 no.3 pp. 831-839
- ISSN:
- 0378-8741
- Subject:
- GATA transcription factors; Musca domestica; Oriental traditional medicine; antibodies; antineoplastic activity; antineoplastic agents; blood serum; cell-mediated immunity; coma; cytotoxic T-lymphocytes; gene expression; immunoglobulin G; immunomodulators; insects; interferon-gamma; interleukin-10; larvae; mechanism of action; messenger RNA; mice; natural killer cells; necrosis; oral administration; osteomyelitis; protein content; sarcoma; splenocytes; stomach neoplasms; transcription (genetics)
- Abstract:
- ... The larvae of Musca domestica (Diptera: Muscidae) have been used traditionally for malnutritional stagnation, decubital necrosis, osteomyelitis, ecthyma and lip scald and also to treat coma and gastric cancer in the traditional Chinese medicine. Its in vitro antitumor activity and immunomodulatory effect in naïve mice in relation to the traditional uses were also reported. However, the in vivo ant ...
- DOI:
- 10.1016/j.jep.2014.03.052
- https://doi.org/10.1016/j.jep.2014.03.052
- Author:
- Erdem Yesilada; İlhan Gürbüz; Gülnur Toker
- Source:
- Journal of ethnopharmacology 2014 v.153 no.2 pp. 478-483
- ISSN:
- 0378-8741
- Subject:
- Sambucus ebulus; abscess; anti-ulcer activity; bioassays; butanol; chromatography; flavonols; fractionation; glycosides; in vivo studies; ion exchange; leaves; methanol; models; nuclear magnetic resonance spectroscopy; pain; peptic ulcers; rats; separation; silica gel; solvents; tissue repair; traditional medicine
- Abstract:
- ... Sambucus ebulus L. has a very prominent place in Turkish folk medicine. Leaves of the plant are practiced externally to relieve rheumatic pain, to treat abscess, for wound healing and internally against hemorrhoids and stomachache. In a previous work, aqueous extract of the leaves was shown to possess potent antiulcerogenic activity on water immersion and immobilization-induced stress ulcer model ...
- DOI:
- 10.1016/j.jep.2014.03.004
- https://doi.org/10.1016/j.jep.2014.03.004
- Author:
- X. Siwe Noundou; R.W.M. Krause; S.F. van Vuuren; D. Tantoh Ndinteh; D.K. Olivier
- Source:
- Journal of ethnopharmacology 2014 v.151 no.2 pp. 1023-1027
- ISSN:
- 0378-8741
- Subject:
- Alchornea; Bacillus cereus; Enterococcus faecalis; Escherichia coli; Gram-negative bacteria; Klebsiella pneumoniae; Moraxella catarrhalis; Proteus mirabilis; Staphylococcus aureus; Staphylococcus saprophyticus; antibacterial properties; chloroform; ethanol; ethyl acetate; fungi; gastrointestinal system; leaf extracts; leaves; methanol; pathogens; phytopharmaceuticals; roots; solvents; stems; traditional medicine; Africa
- Abstract:
- ... Alchornea floribunda Müll. Arg. is used in traditional medicine across Africa for the treatment of bacterial, fungal, parasitic and inflammatory disorders.To evaluate the antibacterial activity of the crude extracts of different plant parts in order to provide a scientific rationale for the proposed broad efficacy of Alchornea floribunda in the treatment of bacterial infections.Extracts of roots, ...
- DOI:
- 10.1016/j.jep.2013.12.002
- https://doi.org/10.1016/j.jep.2013.12.002
- Author:
- Dandan Cheng; Yingying Zhang; Demin Gao; Hongmeng Zhang
- Source:
- Journal of ethnopharmacology 2014 v.155 no.2 pp. 1300-1305
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Pseudomonas aeruginosa; Pyrrosia; aerial parts; agar; anthraquinones; anti-inflammatory activity; anti-inflammatory agents; antibacterial properties; asthma; bronchitis; butanol; cell lines; cytotoxicity; ears; ethanol; ethyl acetate; flavonoids; lung neoplasms; mice; microorganisms; minimum inhibitory concentration; neoplasm cells; petroleum; phenols; pyelonephritis; reducing sugars; saponins; screening; solvents; splenocytes; steroids; terpenoids; xylene
- Abstract:
- ... Pyrrosia petiolosa is commonly used as a traditional Chinese medicine for treatment of acute pyelonephritis, chronic bronchitis and bronchial asthma. This study aims to evaluate the antibacterial activity of the ethanol extract and its derived fractions of Pyrrosia petiolosa obtained with solvents of different polarities and to perform the anti-inflammatory screening.The powdered aerial parts of P ...
- DOI:
- 10.1016/j.jep.2014.07.029
- https://doi.org/10.1016/j.jep.2014.07.029
- Author:
- Daishu Mizuki; Kinzo Matsumoto; Ken Tanaka; Xoan Thi Le; Hironori Fujiwara; Tsutomu Ishikawa; Yoshihiro Higuchi
- Source:
- Journal of ethnopharmacology 2014 v.156 pp. 16-25
- ISSN:
- 0378-8741
- Subject:
- Butea superba; animal models; binding proteins; blood serum; cognitive disorders; corticosterone; dementia; dried herbs; drugs; elderly; hippocampus; immunohistochemistry; males; mechanism of action; medicinal plants; messenger RNA; mice; neurogenesis; plant extracts; sucrose; tail suspension test; tissues; traditional medicine
- Abstract:
- ... Butea superba (BS) is a Thai medicinal plant that has been used as a folk medicine to improve physical and mental conditions and to prevent impaired sexual performance in middle-aged or elderly males. We have previously reported that this plant extract could improve cognitive deficits and depression-like behavior in olfactory bulbectomized mice, an animal model of dementia and depression.In this s ...
- DOI:
- 10.1016/j.jep.2014.08.014
- https://doi.org/10.1016/j.jep.2014.08.014
- Author:
- Ismail O. Ishola; Esther O. Agbaje; Moshood O. Akinleye; Chris O. Ibeh; Olufunmilayo O. Adeyemi
- Source:
- Journal of ethnopharmacology 2014 v.158 pp. 364-372
- ISSN:
- 0378-8741
- Subject:
- traditional medicine; dopamine; antidepressants; leaf extracts; locomotion; dose response; serotonin; antagonists; dopamine receptors; yohimbine; forced swimming test; behavior disorders; Alchornea cordifolia; mice; intraperitoneal injection; alpha-1 adrenergic receptors; oral administration; leaves; alpha-2 adrenergic receptors
- Abstract:
- ... The leaf of Alchornea cordifolia (Euphorbiaceae) is used in traditional African medicine in the treatment of various neurological and psychiatric disorders including depression. Previous studies have shown its potent antidepressant-like effect in the forced swimming test (FST). Hence, this study sought to investigate the involvement of monoaminergic systems in the antidepressant-like effect elicit ...
- DOI:
- 10.1016/j.jep.2014.10.008
- https://doi.org/10.1016/j.jep.2014.10.008
- Author:
- Dan Li; Cheng Peng; Xiaofang Xie; Yu Mao; Min Li; Zhixing Cao; Danqing Fan
- Source:
- Journal of ethnopharmacology 2014 v.153 no.3 pp. 561-567
- ISSN:
- 0378-8741
- Subject:
- Malus toringoides; alloxan; animal disease models; blood glucose; blood serum; body weight; c-peptide; diabetes; flavonoids; glycemic effect; glycogen; glycosylation; hemoglobin; hyperglycemia; hyperlipidemia; hypertension; indigestion; leaves; liver; malondialdehyde; mice; mountains; plant growth; rats; snow; streptozotocin; superoxide dismutase; traditional medicine; China
- Abstract:
- ... The leaf of Malus toringoides (Rehd.) Hughes is a traditional folk medicine in Tibet, China, which is called “E Se” in Tibetan language. This original plant grows on snow mountains at an attitude of 3000 to 3700m. It is primarily used to treat hypertension, hyperlipidemia, hyperglycemia, indigestion and other diseases. This study aimed to evaluate the antidiabetic effect of flavonoids extracted fr ...
- DOI:
- 10.1016/j.jep.2014.02.026
- https://doi.org/10.1016/j.jep.2014.02.026
- Author:
- Hichem Sebai; Mohamed-Amine Jabri; Abdelaziz Souli; Kais Rtibi; Slimen Selmi; Olfa Tebourbi; Jamel El-Benna; Mohsen Sakly
- Source:
- Journal of ethnopharmacology 2014 v.152 no.2 pp. 327-332
- ISSN:
- 0378-8741
- Subject:
- Matricaria chamomilla; antidiarrheal effect; antioxidant activity; castor oil; catalase; chamomile; diarrhea; dose response; glutathione peroxidase; hydrogen peroxide; intestinal mucosa; iron; malondialdehyde; oral administration; oxidative stress; protective effect; rats; superoxide dismutase; traditional medicine
- Abstract:
- ... Matricaria recutita L. (Chamomile) has been widely used in the Tunisian traditional medicine for the treatment of digestive system disorders. The present work aims to investigate the protective effects of chamomile decoction extract (CDE) against castor oil-induced diarrhea and oxidative stress in rats.The antidiarrheal activity was evaluated using castor oil-induced diarrhea method. In this respe ...
- DOI:
- 10.1016/j.jep.2014.01.015
- https://doi.org/10.1016/j.jep.2014.01.015
- Author:
- Delgerbat Boldbaatar; Hesham R. El-Seedi; Meriana Findakly; Safa Jabri; Batkhuu Javzan; Battsetseg Choidash; Ulf Göransson; Björn Hellman
- Source:
- Journal of ethnopharmacology 2014 v.155 no.1 pp. 599-606
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; DNA damage; antioxidant activity; antioxidants; butanol; catechol; comet assay; drugs; flavones; in vitro studies; medicinal plants; methanol; methylene chloride; mice; mutagens; neoplasm cells; traditional medicine; Mongolia
- Abstract:
- ... Leptopyrum fumarioides has been used in the traditional medicine of Mongolia for the treatment of various diseases, including drug intoxications. However, since there is only sparse information about its chemistry, active components, and pharmacological and toxicological effects, the major aim of the present study employing mouse lymphoma cells was to evaluate the genotoxic and antigenotoxic/antio ...
- DOI:
- 10.1016/j.jep.2014.06.005
- https://doi.org/10.1016/j.jep.2014.06.005
- Author:
- Nadir Abuzeid; Sadaf Kalsum; Richin John Koshy; Marie Larsson; Mikaela Glader; Henrik Andersson; Johanna Raffetseder; Elsje Pienaar; Daniel Eklund; Muddathir S. Alhassan; Haidar A. AlGadir; Waleed S. Koko; Thomas Schön; M. Ahmed Mesaik; Omer M. Abdalla; Asaad Khalid; Maria Lerm
- Source:
- Journal of ethnopharmacology 2014 v.157 pp. 134-139
- ISSN:
- 0378-8741
- Subject:
- Khaya senegalensis; Mycobacterium tuberculosis; Rosmarinus officinalis; active ingredients; antibacterial properties; antibiotics; avirulent strains; bark; butanol; chloroform; culture media; cytotoxicity; ethanol; ethyl acetate; fractionation; hexane; hydrophilicity; hydrophobicity; infectious diseases; inhibitory concentration 50; leaf extracts; macrophages; medicinal plants; multiple drug resistance; new drugs; screening; solvents; traditional medicine; Sudan
- Abstract:
- ... The emergence of multidrug-resistant strains of Mycobacterium tuberculosis underscores the need for continuous development of new and efficient methods to determine the susceptibility of isolates of Mycobacterium tuberculosis in the search for novel antimycobacterial agents. Natural products constitute an important source of new drugs, and design and implementation of antimycobacterial susceptibil ...
- DOI:
- 10.1016/j.jep.2014.09.020
- https://doi.org/10.1016/j.jep.2014.09.020
- Author:
- B. Madikizela; A.R. Ndhlala; J.F. Finnie; J. Van Staden
- Source:
- Journal of ethnopharmacology 2014 v.153 no.2 pp. 386-391
- ISSN:
- 0378-8741
- Subject:
- Abrus precatorius; Ficus; Mycobacterium tuberculosis; Phanerophlebia; Salmonella Typhimurium; Terminalia; anti-inflammatory activity; antibacterial properties; bioactive compounds; drug resistance; ethanol; genotoxicity; methylene chloride; minimum inhibitory concentration; petroleum; prostaglandin synthase; screening; solvents; traditional medicine; tuberculosis; South Africa
- Abstract:
- ... Emergence of drug-resistant tuberculosis strains and long duration of treatment has established an urgent need to search for new effective agents. The great floral diversity of South Africa has potential for producing new bioactive compounds, therefore pharmacological screening of plant extracts within this region offers much potential. To assess the in vitro antimycobacterial, anti-inflammatory a ...
- DOI:
- 10.1016/j.jep.2014.02.034
- https://doi.org/10.1016/j.jep.2014.02.034
- Author:
- Yu Wang; Ping Chen; Changyun Tang; Yao Wang; Yazhen Li; Hao Zhang
- Source:
- Journal of ethnopharmacology 2014 v.151 no.2 pp. 944-950
- ISSN:
- 0378-8741
- Subject:
- Carthamus tinctorius; acetic acid; analgesic effect; animal models; anti-inflammatory activity; anti-inflammatory agents; aspirin; dose response; ears; edema; formalin; formalin test; glycosides; high performance liquid chromatography; inflammation; kaempferol; mice; nociception; oral administration; pain; traditional medicine; writhing test; China
- Abstract:
- ... Safflower (Carthamus tinctorius L.) has been long used both in the traditional system and folk medicine as an analgesic anti-inflammatory agent in China. The aim of the study was to evaluate the antinociceptive and anti-inflammatory activities of hydroalcoholic extract (HE) and two isolated kaempferol glycosides of Carthamus tinctorius L. to provide experimental evidence for its traditional use.An ...
- DOI:
- 10.1016/j.jep.2013.12.003
- https://doi.org/10.1016/j.jep.2013.12.003
- Author:
- Olusegun Adebayo Adeoluwa; Adegbuyi Oladele Aderibigbe; Elizabeth Toyin Olonode
- Source:
- Journal of ethnopharmacology 2014 v.156 pp. 353-357
- ISSN:
- 0378-8741
- Subject:
- Erythropalaceae; acetic acid; analgesics; behavior disorders; dose response; formalin; hot plate test; latent period; leaves; mice; neoplasms; pain; shrubs; tail; traditional medicine; trees; Nigeria
- Abstract:
- ... Olax subscorpioidea is a shrub or tree found in Nigeria, and other parts of Africa. It is used in the management of inflammatory disorder, mental illness, convulsion, pain, and cancer. However, there is dearth of information on scientific basis for its folkloric use in the management of pain. Therefore, the study was designed to investigate the antinociceptive property of the extract of Olax subsc ...
- DOI:
- 10.1016/j.jep.2014.08.040
- https://doi.org/10.1016/j.jep.2014.08.040
- Author:
- Chun-Feng Zhang; Su-Li Zhang; Xin He; Xiao-Lin Yang; Hai-Tao Wu; Bao-Qin Lin; Cui-Ping Jiang; Jun Wang; Chun-Hao Yu; Zhong-Lin Yang; Chong-Zhi Wang; Ping Li; Chun-Su Yuan
- Source:
- Journal of ethnopharmacology 2014 v.153 no.3 pp. 793-800
- ISSN:
- 0378-8741
- Subject:
- Daphne genkwa; adjuvants; animal models; antioxidant activity; antioxidants; apigenin; blood viscosity; edema; herbal medicines; high performance liquid chromatography; histopathology; inflammation; luteolin; mass spectrometry; oxidative stress; pain; rats; rheumatoid arthritis; traditional medicine; weight loss; China
- Abstract:
- ... Genkwa flos (Daphne genkwa Sieb. et Zucc.), a Chinese herbal medicine, has been traditionally used for over two thousand years in China for inflammation related symptoms, including joint pain. To evaluate the antioxidative effects of flavonoid aglycones (FA) isolated from Genkwa flos on adjuvant arthritis in rats and to identify the relationship between antioxidant potential and whole blood viscos ...
- DOI:
- 10.1016/j.jep.2014.03.046
- https://doi.org/10.1016/j.jep.2014.03.046
- Author:
- Maria do Rosário Martins; Silvia Arantes; Fátima Candeias; Maria Teresa Tinoco; Júlio Cruz-Morais
- Source:
- Journal of ethnopharmacology 2014 v.151 no.1 pp. 485-492
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Artemia salina; Schinus molle; acute toxicity; agar; alpha-phellandrene; alpha-pinene; analgesics; antimicrobial properties; antioxidant activity; antioxidants; antiseptics; bacteria; beta-phellandrene; chemical composition; essential oils; food industry; free radicals; fruits; gas chromatography-mass spectrometry; leaves; limonene; mice; minimum inhibitory concentration; myrcene; parasympatholytics; pharmaceutical industry; screening; spoilage fungi; traditional medicine
- Abstract:
- ... Schinus molle L. has been used in folk medicine as antibacterial, antiviral, topical antiseptic, antifungal, antioxidant, anti-inflammatory, anti-tumoural as well as antispasmodic and analgesic; however, there are few studies of pharmacological and toxicological properties of Schinus molle essential oils. The aim of this study was to evaluate the antioxidant and antimicrobial activities of Schinus ...
- DOI:
- 10.1016/j.jep.2013.10.063
- https://doi.org/10.1016/j.jep.2013.10.063
- Author:
- Guillermo Schmeda-Hirschmann; Cristina Quispe; Cristina Theoduloz; Paulo Teixeira de Sousa; Carlos Parizotto
- Source:
- Journal of ethnopharmacology 2014 v.155 no.2 pp. 1076-1085
- ISSN:
- 0378-8741
- Subject:
- Bufo; pressing; leukemia; erysipelas; neoplasm cells; spectral analysis; lungs; epithelium; inhibitory concentration 50; bladder; etoposide; alkaloids; toad venoms; spectroscopy; traditional medicine; human cell lines; bufadienolides; lung neoplasms; adenocarcinoma; Rhinella; toads; wetlands; parotid gland; bioactive properties; fibroblasts; Pantanal
- Abstract:
- ... Toads known as “cururú” (Rhinella schneideri) have been used in the Brazilian Pantanal and Paraguayan Chaco wetlands to treat erysipelas and cancer. The aim of the study was to assess the antiproliferative effect of the venom obtained from Rhinella schneideri and to identify its constituents by spectroscopic and spectrometric methods.The venom was obtained by gentle pressing the parotid glands of ...
- DOI:
- 10.1016/j.jep.2014.06.025
- https://doi.org/10.1016/j.jep.2014.06.025
- Author:
- Jinlian Zhao; Dimitrios Evangelopoulos; Sanjib Bhakta; Alexander I. Gray; Véronique Seidel
- Source:
- Journal of ethnopharmacology 2014 v.155 no.1 pp. 796-800
- ISSN:
- 0378-8741
- Subject:
- 4-hydroxybenzoic acid; Arctium lappa; Mycobacterium tuberculosis; Tussilago farfara; ethyl acetate; growth retardation; hexane; kaempferol; methanol; methylene chloride; nuclear magnetic resonance spectroscopy; p-coumaric acid; quercetin; sitosterols; spectral analysis; stigmasterol; traditional medicine
- Abstract:
- ... Arctium lappa and Tussilago farfara (Asteraceae) are two plant species used traditionally as antitubercular remedies. The aim of this study was (i) to screen Arctium lappa and Tussilago farfara extracts for activity against Mycobacterium tuberculosis and (ii) to isolate and identify the compound(s) responsible for this reputed anti-TB effect.The activity of extracts and isolated compounds was dete ...
- DOI:
- 10.1016/j.jep.2014.06.034
- https://doi.org/10.1016/j.jep.2014.06.034