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- Marianne Molander; Line Nielsen; Søren Søgaard; Dan Staerk; Nina Rønsted; Drissa Diallo; Kusamba Zacharie Chifundera; Johannes van Staden; Anna K. Jäger
- Journal of ethnopharmacology 2014 v.157 pp. 171-180
- Bauhinia thonningii; Bitis arietans; Combretum; Grewia mollis; Lannea; Naja; Strychnos; active ingredients; antiserum; bioassays; enzyme inhibition; enzyme inhibitors; ethanol; hyaluronoglucosaminidase; inhibitory concentration 50; mortality; necrosis; patients; phospholipase A2; plant anatomy; polyphenols; proteinases; snake bites; snakes; traditional medicine; Democratic Republic of the Congo; Mali; South Africa
- ... Snakebite envenomation, every year, causes estimated 5–10,000 mortalities and results in more than 5–15,000 amputations in sub-Saharan Africa alone. Antiserum is not easily accessible in these regions or doctors are simply not available, thus more than 80% of all patients seek traditional practitioners as first-choice. Therefore it is important to investigate whether the plants used in traditional ...
- Francine Nsuadi Manga; Charaf El Khattabi; Jeanine Fontaine; Guy Berkenboom; Pierre Duez; José Lami Nzunzu; Stéphanie Pochet
- Journal of ethnopharmacology 2012 v.142 no.1 pp. 194-200
- Combretum; antihypertensive effect; antioxidant activity; aorta; bark; endothelium; esters; flavonoids; free radicals; guanylate cyclase; hypertension; indomethacin; leaves; nitric oxide synthase; phenylephrine; plant extracts; prostaglandin synthase; rats; roots; systolic blood pressure; traditional medicine; vasodilation; Democratic Republic of the Congo
- ... ETHNOPHARMACOLOGICAL RELEVANCE: Combretum racemosum P. Beauv (Combretaceae) leaves (CrLv) and root bark (CrRB) and Combretum celastroides subsp. laxiflorum Welw (Combretaceae) leaves (ClLv) are used in Congolese traditional medicine for several therapeutic purposes, notably for the treatment of conditions consistent with hypertension. The present study aims to investigate the vasorelaxant and in v ...