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Journal of ethnopharmacology
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Democratic Republic of the Congo
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- Author:
- Bagalwa, M.; Chifundera, K.
- Source:
- Journal of ethnopharmacology 2007 v.114 no.3 pp. 281-284
- ISSN:
- 0378-8741
- Subject:
- pesticidal plants; Maesa; stems; ecotoxicology; mollusc control; indigenous knowledge; medicinal plants; plant extracts; snails; pesticidal properties; aquatic invertebrates; saponins; environmental impact; insect control; bark; imagos; herbal medicines; Democratic Republic of the Congo
- DOI:
- 10.1016/j.jep.2005.11.036
- PubMed:
- 17928180
- https://doi.org/10.1016/j.jep.2005.11.036
- Author:
- Mesia, G.K.; Tona, G.L.; Nanga, T.H.; Cimanga, R.K.; Apers, S.; Cos, P.; Maes, L.; Pieters, L.; Vlietinck, A.J.
- Source:
- Journal of ethnopharmacology 2008 v.115 no.3 pp. 409-415
- ISSN:
- 0378-8741
- Subject:
- inhibitory concentration 50; Plasmodium falciparum; viability; interspecific variation; antiprotozoal agents; dose response; Trypanosoma brucei brucei; cytotoxicity; medicinal plants; plant extracts; Trypanosoma cruzi; dosage; in vitro studies; medicinal properties; cell lines; cell proliferation; culture media; Democratic Republic of the Congo
- Abstract:
- ... Aim of the study: : To evaluate in vitro the antiprotozoal and cytotoxic activies of 80% methanol extract from 45 medicinal plants collected in Sankuru (Democratic Republic of Congo) against Trypanosoma brucei brucei, Trypanosoma cruzi and the chloroquine-sensitive Ghanaian strain of Plasmodium falciparum, and MRC-5 cell lines respectively. Material and methods: : Differents extracts were obtained ...
- DOI:
- 10.1016/j.jep.2007.10.028
- https://doi.org/10.1016/j.jep.2007.10.028
- Author:
- Mpiana, P.T.; Mudogo, V.; Tshibangu, D.S.T.; Kitwa, E.K.; Kanangila, A.B.; Lumbu, J.B.S.; Ngbolua, K.N.; Atibu, E.K.; Kakule, M.K.
- Source:
- Journal of ethnopharmacology 2008 v.120 no.3 pp. 413-418
- ISSN:
- 0378-8741
- Subject:
- medicinal properties; medicinal plants; anthocyanins; traditional medicine; chemical constituents of plants; sickle cell anemia; Bombax; Ficus; Ziziphus; photolysis; surveys; in vitro studies; plant extracts; ultraviolet radiation; solar radiation; Democratic Republic of the Congo
- Abstract:
- ... Aim of the study: A survey was conducted in Lubumbashi city (Democratic Republic of Congo) in order to: (a) identify medicinal plants used by traditional healers in the management of sickle cell anaemia, (b) verify their antisickling activity in vitro, (c) determine the most active plants, and (d) verify if anthocyanins are responsible of the bioactivity and study their photodegradation effect. Ma ...
- DOI:
- 10.1016/j.jep.2008.09.012
- PubMed:
- 18930798
- https://doi.org/10.1016/j.jep.2008.09.012
- Author:
- Mesia, Kahunu; Cimanga, Richard K.; Dhooghe, Liene; Cos, Paul; Apers, Sandra; Totté, Jozef; Tona, Gaston L.; Pieters, Luc; Vlietinck, Arnold J.; Maes, Louis
- Source:
- Journal of ethnopharmacology 2010 v.131 no.1 pp. 10-16
- ISSN:
- 0378-8741
- Subject:
- Nauclea; medicinal plants; plant extracts; antimicrobial properties; Plasmodium falciparum; in vitro studies; antimalarials; bark; solvents; mice; animal models; Plasmodium berghei; malaria; in vivo studies; inhibitory concentration 50; dosage; cultured cells; cytotoxicity; oral administration; mortality; intestinal absorption; acute toxicity; Democratic Republic of the Congo
- Abstract:
- ... Aim of the study: To evaluate the in vitro and in vivo antiplasmodial activity and toxicity of the aqueous and 80% EtOH extract of the stem bark of Nauclea pobeguinii (Pob. Ex. Pell.) Petit (Rubiaceae), a plant used in traditional medicine in DR Congo against malaria. Materials and methods: The aqueous and 80% EtOH extract from N. pobeguinii stem bark, and its constituents (5S)-5-carboxystrictosid ...
- DOI:
- 10.1016/j.jep.2010.05.008
- PubMed:
- 20470876
- https://doi.org/10.1016/j.jep.2010.05.008
- Author:
- Lusakibanza, M.; Mesia, G.; Tona, G.; Karemere, S.; Lukuka, A.; Tits, M.; Angenot, L.; Frédérich, M.
- Source:
- Journal of ethnopharmacology 2010 v.129 no.3 pp. 398-402
- ISSN:
- 0378-8741
- Subject:
- medicinal plants; traditional medicine; herbal medicines; antimicrobial properties; antimalarials; Plasmodium falciparum; animal pathogens; malaria; plant extracts; cytotoxicity; in vitro studies; ethnobotany; microbial growth; lactate dehydrogenase; solvents; strain differences; human cell lines; fibroblasts; dosage; inhibitory concentration 50; Democratic Republic of the Congo
- Abstract:
- ... Aim of the study: The in vitro antiplasmodial activity and cytotoxicity of methanolic and dichloromethane extracts from five Congolese plants were evaluated. The plants were selected following an ethnobotanical survey conducted in D.R. Congo and focusing on plants used traditionally to treat malaria. The in vivo antimalarial activity of aqueous and methanolic extracts active in vitro was also dete ...
- DOI:
- 10.1016/j.jep.2010.04.007
- PubMed:
- 20430094
- https://doi.org/10.1016/j.jep.2010.04.007
- Author:
- S. Nsaka Lumpu; G. Tona Lutete; O. Kambu Kabangu; R. Cimanga Kanyanga; S. Apers; L. Pieters; A.J. Vlietinck
- Source:
- Journal of ethnopharmacology 2012 v.142 no.3 pp. 620-626
- ISSN:
- 0378-8741
- Subject:
- Alstonia; Proteus; alkaloids; antibacterial properties; antidiarrheal effect; bacteria; body weight; castor oil; chloroform; defecation; diarrhea; leaves; magnesium; medicine; methanol; rats; tannins; Democratic Republic of the Congo
- Abstract:
- ... AIM OF THE STUDY: To evaluate the antidiarrhoeal properties of Alstonia congensis leaves claimed to be effective for the treatment of diarrhoea by traditional healers during our ethnopharmacological investigation conducted in Kinshasa, Democratic Republic of Congo. MATERIALS AND METHODS: The aqueous extract (decoction), and the 80% hot methanol extract (Soxhlet extraction) were obtained. This last ...
- DOI:
- 10.1016/j.jep.2012.04.038
- PubMed:
- 22609154
- https://doi.org/10.1016/j.jep.2012.04.038
- Author:
- M. Katemo; P.T. Mpiana; B.M. Mbala; S.O. Mihigo; K.N. Ngbolua; D.S.T. Tshibangu; P.R. Koyange
- Source:
- Journal of ethnopharmacology 2012 v.144 no.1 pp. 39-43
- ISSN:
- 0378-8741
- Subject:
- diabetes; inventories; leaves; nationalities and ethnic groups; patients; recipes; surveys; traditional medicine; Democratic Republic of the Congo
- Abstract:
- ... ETHNOPHARMACOLOGICAL RELEVANCE: An ethnopharmacological survey was conducted in Kisangani City (Democratic Republic of Congo) in order to make an inventory of plant species used in folk medicine for the management of diabetes and their different modes of preparation. MATERIALS AND METHODS: Fifty-five traditional practitioners from different ethnic groups were interviewed about the plants they use ...
- DOI:
- 10.1016/j.jep.2012.08.022
- PubMed:
- 22947387
- https://doi.org/10.1016/j.jep.2012.08.022
- Author:
- D. Musuyu Muganza; B.I. Fruth; J. Nzunzu Lami; G.K. Mesia; O.K. Kambu; G.L. Tona; R. Cimanga Kanyanga; P. Cos; L. Maes; S. Apers; L. Pieters
- Source:
- Journal of ethnopharmacology 2012 v.141 no.1 pp. 301-308
- ISSN:
- 0378-8741
- Subject:
- Annickia; Isolona; Leishmania infantum; Piptadeniastrum; Plasmodium falciparum; Quassia; Trypanosoma brucei; Trypanosoma cruzi; bark; cytotoxicity; inventories; medicinal plants; parasitoses; plant extracts; roots; stems; Democratic Republic of the Congo; Republic of the Congo
- Abstract:
- ... ETHNOPHARMACOLOGICAL RELEVANCE: The antiprotozoal and cytotoxic activity of the aqueous extracts from 33 medicinal plants, used by traditional healers for the treatment of various parasitic diseases and collected after an ethnopharmacological inventory conducted in the Bolongo area, Bandundu province in DR Congo, was evaluated. MATERIALS AND METHODS: Decoctions were prepared, lyophilized and evalu ...
- DOI:
- 10.1016/j.jep.2012.02.035
- PubMed:
- 22394563
- https://doi.org/10.1016/j.jep.2012.02.035
9. Vascular effects and antioxidant activity of two Combretum species from Democratic Republic of Congo
- Author:
- Francine Nsuadi Manga; Charaf El Khattabi; Jeanine Fontaine; Guy Berkenboom; Pierre Duez; José Lami Nzunzu; Stéphanie Pochet
- Source:
- Journal of ethnopharmacology 2012 v.142 no.1 pp. 194-200
- ISSN:
- 0378-8741
- Subject:
- Combretum; antihypertensive effect; antioxidant activity; aorta; bark; endothelium; esters; flavonoids; free radicals; guanylate cyclase; hypertension; indomethacin; leaves; nitric oxide synthase; phenylephrine; plant extracts; prostaglandin synthase; rats; roots; systolic blood pressure; traditional medicine; vasodilation; Democratic Republic of the Congo
- Abstract:
- ... ETHNOPHARMACOLOGICAL RELEVANCE: Combretum racemosum P. Beauv (Combretaceae) leaves (CrLv) and root bark (CrRB) and Combretum celastroides subsp. laxiflorum Welw (Combretaceae) leaves (ClLv) are used in Congolese traditional medicine for several therapeutic purposes, notably for the treatment of conditions consistent with hypertension. The present study aims to investigate the vasorelaxant and in v ...
- DOI:
- 10.1016/j.jep.2012.04.039
- PubMed:
- 22564815
- https://doi.org/10.1016/j.jep.2012.04.039
- Author:
- Marie Miezi Nsimba; José Nzunzu Lami; Yumiko Hayakawa; Chika Yamamoto; Toshiyuki Kaji
- Source:
- Journal of ethnopharmacology 2013 v.148 no.3 pp. 895-900
- ISSN:
- 0378-8741
- Subject:
- Ceiba pentandra; Quassia; blood coagulation; coagulation; medicine; pathogenesis; prothrombin; sickle cell anemia; thrombin; thromboplastin; Democratic Republic of the Congo
- Abstract:
- ... Ethnopharmacological relevance: Aqueous extracts from Ceiba pentandra (Malvaceae/Bombacoideae) and Quassia africana (Simaroubaceae) are used as crude medicines for the management of sickle cell anemia (SCA) in the Democratic Republic of Congo (DR Congo). Since it is postulated that the pathogenesis of SCA is associated with an increased blood coagulation activity, the present study is conducted to ...
- DOI:
- 10.1016/j.jep.2013.05.038
- PubMed:
- 23711829
- https://doi.org/10.1016/j.jep.2013.05.038
- Author:
- Marie Miezi Nsimba; Chika Yamamoto; José Nzunzu Lami; Yumiko Hayakawa; Toshiyuki Kaji
- Source:
- Journal of ethnopharmacology 2013 v.146 no.2 pp. 594-599
- ISSN:
- 0378-8741
- Subject:
- Ceiba pentandra; RNA; biosynthesis; digestion; endothelial cells; fibrin; fibrinolysis; heparin; humans; medicine; plasminogen; plasminogen activator; secretion; sickle cell anemia; Democratic Republic of the Congo
- Abstract:
- ... ETHNOPHARMACOLOGICAL RELEVANCE: Aqueous extract of Ceiba pentandra, which is used for the management of sickle cell anemia (SCA) in DR Congo, exhibits antithrombin response by activation of Heparin cofactor II in vitro. This study examines the effect of the plant on the fibrinolytic activity to understand whether it can influence the coagulation–fibrinolysis system, since fibrinolysis disorder is ...
- DOI:
- 10.1016/j.jep.2013.01.031
- PubMed:
- 23376284
- https://doi.org/10.1016/j.jep.2013.01.031
- Author:
- K.N. Ngbolua; P.T. Mpiana; V. Mudogo; D.S.T. Tshibangu; N.K. Ngombe; E. Ekutsu; O.N. Kabena; B.Z. Gbolo; C.L. Muanyishay; K. Lassa
- Source:
- Journal of ethnopharmacology 2013 pp. -
- ISSN:
- 0378-8741
- Subject:
- Rubiaceae; bark; biological resources; cell culture; ex situ conservation; herbaria; infectious diseases; malaria; medicinal plants; nationalities and ethnic groups; patients; phanerophytes; recipes; surveys; traditional medicine; Democratic Republic of the Congo
- Abstract:
- ... : An ethno-botanical survey was conducted among traditional healers in Kinshasa, Democratic Republic of Congo in order to identify plant species used in folk medicine to treat parasitic and infectious diseases.: Forty traditional healers from different ethnic groups were interviewed about plants used in Congolese folk medicine to treat parasitic and infectious diseases in Kinshasa. Cited plants we ...
- DOI:
- 10.1016/j.jep.2013.04.015
- https://doi.org/10.1016/j.jep.2013.04.015
- Author:
- Marianne Molander; Line Nielsen; Søren Søgaard; Dan Staerk; Nina Rønsted; Drissa Diallo; Kusamba Zacharie Chifundera; Johannes van Staden; Anna K. Jäger
- Source:
- Journal of ethnopharmacology 2014 v.157 pp. 171-180
- ISSN:
- 0378-8741
- Subject:
- Bauhinia thonningii; Bitis arietans; Combretum; Grewia mollis; Lannea; Naja; Strychnos; active ingredients; antiserum; bioassays; enzyme inhibition; enzyme inhibitors; ethanol; hyaluronoglucosaminidase; inhibitory concentration 50; mortality; necrosis; patients; phospholipase A2; plant anatomy; polyphenols; proteinases; snake bites; snakes; traditional medicine; Democratic Republic of the Congo; Mali; South Africa
- Abstract:
- ... Snakebite envenomation, every year, causes estimated 5–10,000 mortalities and results in more than 5–15,000 amputations in sub-Saharan Africa alone. Antiserum is not easily accessible in these regions or doctors are simply not available, thus more than 80% of all patients seek traditional practitioners as first-choice. Therefore it is important to investigate whether the plants used in traditional ...
- DOI:
- 10.1016/j.jep.2014.09.027
- https://doi.org/10.1016/j.jep.2014.09.027
- Author:
- Victor Okombe Embeya; Jean-Baptiste Lumbu Simbi; Caroline Stévigny; Sandrina Vandenput; Célestin Pongombo Shongo; Pierre Duez
- Source:
- Journal of ethnopharmacology 2014 v.153 no.3 pp. 686-693
- ISSN:
- 0378-8741
- Subject:
- Verbenaceae; Vitex; affordability; agronomists; cattle; deworming; digestive system diseases; drugs; etiology; farmers; gastrointestinal system; goats; herbaria; indigenous knowledge; inventories; medicinal plants; parasitoses; questionnaires; surveys; traditional medicine; veterinarians; Democratic Republic of the Congo
- Abstract:
- ... Gastrointestinal parasitic diseases present one of the main constraints hindering the productivity of the livestock sector (goat and cattle). Due to the limited availability and affordability of deworming drugs, traditional herbal remedies are still frequently used. The study aims at collecting traditional knowledge on local plants and remedies used to treat gastrointestinal parasitoses in livesto ...
- DOI:
- 10.1016/j.jep.2014.03.027
- https://doi.org/10.1016/j.jep.2014.03.027
- Author:
- D. Musuyu Muganza; B. Fruth; J. Lami Nzunzu; E. Tuenter; K. Foubert; P. Cos; L. Maes; R. Cimanga Kanyanga; V. Exarchou; S. Apers; L. Pieters
- Source:
- Journal of ethnopharmacology 2016 v.193 pp. 510-516
- ISSN:
- 0378-8741
- Subject:
- Leishmania infantum; Plasmodium falciparum; Polyalthia; Trypanosoma brucei brucei; alkaloids; bark; chloroquine; chromatography; cytotoxicity; ethanol; fruits; in vitro studies; indigenous peoples; inhibitory concentration 50; leaves; malaria; methanol; plant extracts; spectroscopy; traditional medicine; trees; triterpenoids; Democratic Republic of the Congo
- Abstract:
- ... The Nkundo people (Nkundo area of Bolongo, Mai-Ndombe district, Bandundu Province, DR Congo) use various plant parts of the tree Greenwayodendron suaveolens (Engl. & Diels) Verdc. (syn. Polyalthia suaveolens Engl. & Diels) (Annonaceae) against malaria, but its antiprotozoal constituents are not known.The crude 80% ethanol extract from the fruits, leaves, root bark and stem bark and 16 fractions we ...
- DOI:
- 10.1016/j.jep.2016.09.051
- https://doi.org/10.1016/j.jep.2016.09.051
- Author:
- P. Tshisekedi Tshibangu; P. Mutwale Kapepula; M.J. Kabongo Kapinga; A. Tujibikila Mukuta; Dibungi T. Kalenda; Alembert T. Tchinda; Ange A. Mouithys-Mickalad; O. Jansen; E. Cieckiewicz; M. Tits; L. Angenot; M. Frédérich
- Source:
- Journal of ethnopharmacology 2017 v.196 pp. 261-266
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Fourier transform infrared spectroscopy; Plasmodium berghei; Plasmodium falciparum; Rubiaceae; antimalarials; antioxidant activity; bark; colorimetry; cytotoxicity; ethanol; fibroblasts; fractionation; fruits; high performance liquid chromatography; humans; in vitro studies; inhibitory concentration 50; iridoids; leaf extracts; malaria; markets; methanol; methylene chloride; mice; nuclear magnetic resonance spectroscopy; parasites; traditional medicine; Democratic Republic of the Congo
- Abstract:
- ... Heinsia crinita is used in traditional medicine for the treatment of febrile illness and erectile dysfunction. Its stem bark powder is found in some peripheral markets in the Democratic Republic of the Congo (DRC) as a remedy against malaria. Investigations were conducted on crude extracts of leaves, fruits and stem barks in view to validate their use and to determine which plant part possesses th ...
- DOI:
- 10.1016/j.jep.2016.11.041
- https://doi.org/10.1016/j.jep.2016.11.041
- Author:
- Mboni Henry Manya; Flore Keymeulen; Jérémie Ngezahayo; Amuri Salvius Bakari; Mutombo Emery Kalonda; Byanga Joh Kahumba; Pierre Duez; Caroline Stévigny; Simbi Jean-Baptiste Lumbu
- Source:
- Journal of ethnopharmacology 2020 v.249 pp. 112422
- ISSN:
- 0378-8741
- Subject:
- Artemisia annua; Carica papaya; Fabaceae; Rubiaceae; active ingredients; antimalarials; common names; ethnobotany; herbal medicines; herbaria; interviews; leaves; malaria; surveys; traditional medicine; type collections; Democratic Republic of the Congo
- Abstract:
- ... The main objective of the present study was to collect and gather information on herbal remedies traditionally used for the treatment of malaria in Bukavu and Uvira, two towns of the South Kivu province in DRC.Direct interview with field enquiries allowed collecting ethnobotanical data; for each plant, a specimen was harvested in the presence of the interviewed traditional healers (THs). The recor ...
- DOI:
- 10.1016/j.jep.2019.112422
- https://doi.org/10.1016/j.jep.2019.112422