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You searched for: Journal Journal of medicinal food Remove constraint Journal: Journal of medicinal food Subject antineoplastic agents Remove constraint Subject: antineoplastic agents Subject term antineoplastic activity Remove constraint Subject term: antineoplastic activity
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1. Assessing Anticancer Potential of Blueberry Flavonoids, Quercetin, Kaempferol, and Gentisic Acid, Through Oxidative Stress and Apoptosis Parameters on HCT-116 Cells

Author:
Ebru Demirel Sezer; Latife Merve Oktay; Elif Karadadaş; Hikmet Memmedov; Nur Selvi Gunel; Eser Sözmen
Source:
Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
ISSN:
1557-7600
Subject:
2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
Abstract:
... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
DOI:
10.1089/jmf.2019.0098

2. Sulforaphane Decrease of SERTAD1 Expression Triggers G1/S Arrest in Breast Cancer Cells

Author:
An-Chin Cheng; Ching-Ju Shen; Chao-Ming Hung; Yi-Chiang Hsu
Source:
Journal of medicinal food 2019 v.22 no.5 pp. 444-450
ISSN:
1557-7600
Subject:
DNA; antineoplastic activity; antineoplastic agents; breast neoplasms; carcinoma; cell cycle checkpoints; cell proliferation; chemoprevention; cyclins; flow cytometry; histone deacetylase; interphase; neoplasm cells; sulforaphane
Abstract:
... Studies have identified the potential of chemopreventive effects of sulforaphane (SFN); however, the underlying mechanisms of its effect on breast cancer require further elucidation. This study investigated the anticancer effects of SFN that specifically induces G1/S arrest in breast ductal carcinoma (ZR-75-1) cells. The proliferation of the cancer cells after treatment with SFN was detected by 3- ...
DOI:
10.1089/jmf.2018.4195
PubMed:
31084542
PubMed Central:
PMC6534085

3. Antiproliferative Activity of Extracts of Campomanesia adamantium (Cambess.) O. Berg and Isolated Compound Dimethylchalcone Against B16-F10 Murine Melanoma

Author:
Magalli C.B. Lima e Silva; Danielle Bogo; Caroline A.F. Alexandrino; Renata T. Perdomo; Patrícia de O. Figueiredo; Pamela R. do Prado; Fernanda R. Garcez; Monica C.T. Kadri; Thalita V.N. Ximenes; Rita de Cassia A. Guimarães; Ulana C. Sarmento; Maria Lígia R. Macedo
Source:
Journal of medicinal food 2018 v.21 no.10 pp. 1024-1034
ISSN:
1557-7600
Subject:
Campomanesia; antineoplastic activity; antineoplastic agents; apoptosis; bioactive compounds; caspase-3; cerrado; coculture; diodes; fruit pulp; fruits; high performance liquid chromatography; indigenous species; ionization; macrophages; melanoma; methylene chloride; mice; nitric oxide; phenolic compounds; spectrometers
Abstract:
... Campomanesia adamantium, a native species of the Brazilian Cerrado, is characterized as a natural source of phenolic compounds and has known potential anticancer activities. This study aimed to evaluate the chemical profile of dichloromethane extracts of pulp (DEGPU) and peel (DEGPE) from the fruits of C. adamantium and to identify compounds with antiproliferative effects in vitro against melanoma ...
DOI:
10.1089/jmf.2018.0001

4. Fermented Extraction of Citrus unshiu Peel Inhibits Viability and Migration of Human Pancreatic Cancers

Author:
Jungwhoi Lee; Jungsul Lee; Myungseung Kim; Jae Hoon Kim
Source:
Journal of medicinal food 2018 v.21 no.1 pp. 5-12
ISSN:
1557-7600
Subject:
Citrus unshiu; adverse effects; antineoplastic activity; antineoplastic agents; byproducts; caspase-3; computer simulation; hesperetin; hesperidin; human diseases; human umbilical vein endothelial cells; juices; models; mortality; naringenin; neoplasm cells; pancreatic neoplasms; prognosis; signal transduction; viability
Abstract:
... Pancreatic cancer is one of the most dangerous cancers with high mortality rates. Despite continuous efforts, there has been limited improvement in its prognosis. In this study, we prepared fermented extract of Citrus unshiu peel (fCUP) from the by-product after juice processing and then examined the anticancer effects of fCUP on human pancreatic cancer cells. Treatment with fCUP inhibited the gro ...
DOI:
10.1089/jmf.2017.3984

5. Chlorogenic Acid-Enriched Extract of Ilex kudingcha C.J. Tseng Inhibits Angiogenesis in Zebrafish

Author:
Zhong Tao; Piao Linghua; Kim Hyun Jung; Liu Xiande; Jiang Shengnan; Liu Guomin
Source:
Journal of medicinal food 2017 v.20 no.12 pp. 1160-1167
ISSN:
1557-7600
Subject:
Danio rerio; Ilex kaushue; angiogenesis; antineoplastic activity; antineoplastic agents; apoptosis; blood; chlorogenic acid; dose response; endothelial cells; eyes; fever; high performance liquid chromatography; ingredients; magnetism; nuclear magnetic resonance spectroscopy; pruritus; tea; toxins; China
Abstract:
... Kudingcha is a particularly bitter tasting tea that has been widely used in China to eliminate fever and itching eyes, and to clear blood toxins. Kudingcha is considered of value for its potential anticancer effects that are attributed to the presence of characteristic bioactive ingredients. The chlorogenic acid (CGA) derivatives 3-0-caffeoylquinic acid, 5-0-caffeoylquinic acid, 3,5-0-dicaffeoylqu ...
DOI:
10.1089/jmf.2017.3987

6. Production of Bioactive Compounds with Antitumor Activity Against Sarcoma 180 by Pleurotus sajor-caju

Author:
Assis Ivaneliza Simionato; Chaves Mariane Bonatti; Silveira Marcia Luciane Lange; Gern Regina Maria Miranda; Wisbeck Elisabeth; Júnior Agenor Furigo; Furlan Sandra Aparecida
Source:
Journal of medicinal food 2013 v.16 no.11 pp. 1004-1012
ISSN:
1557-7600
Subject:
Pleurotus sajor-caju; ammonium sulfate; antineoplastic activity; antineoplastic agents; biomass; bioreactors; calcium carbonate; containers; culture media; exopolysaccharides; glucose; growth retardation; mice; mycelium; pH; peptones; sarcoma; yeast extract
Abstract:
... This work studied the influence of culture medium composition and pH on exopolysaccharide (EPS) production by Pleurotus sajor-caju and validates the antitumor activity of the produced EPSs and of the mycelial biomass (intracellular polysaccharides [IPSs]) against Sarcoma 180 (S180) cells. The effect of the initial concentrations of (NH₄)₂SO₄, yeast extract and soy peptone on EPS production by P. s ...
DOI:
10.1089/jmf.2012.0267