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You searched for: Journal Veterinary immunology and immunopathology Remove constraint Journal: Veterinary immunology and immunopathology Journal name Veterinary immunology and immunopathology Remove constraint Journal name: Veterinary immunology and immunopathology Publication Year 2016 Remove constraint Publication Year: 2016
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1. IL- 23/IL-17/G-CSF pathway is associated with granulocyte recruitment to the lung during African swine fever

Author:
Z. Karalyan; H. Voskanyan; Z. Ter-Pogossyan; D. Saroyan; E. Karalova
Source:
Veterinary immunology and immunopathology 2016 v.179 pp. 58-62
ISSN:
0165-2427
Subject:
African swine fever; blood serum; enzyme-linked immunosorbent assay; granulocyte colony-stimulating factor; inflammation; interleukin-17; interleukin-23; neutropenia; neutrophils; swine; tissues; viruses
Abstract:
... The interleukin (IL)-23/IL-17 pathway plays a crucial role in various forms of inflammation but its function in acute African swine fever (ASF) is not well understood. Thus, in this study, we aimed to find out whether IL-23/IL-17/G-CSF is released in acute ASF and what function it may have.The present study revealed that the production of IL-17 and IL-23 were significantly increased in the sera of ...
DOI:
10.1016/j.vetimm.2016.08.005

2. Activation of bovine neutrophils by Brucella spp

Author:
Lauren L. Keleher; Jerod A. Skyberg
Source:
Veterinary immunology and immunopathology 2016 v.177 pp. 1-6
ISSN:
0165-2427
Subject:
Brucella melitensis biovar Abortus; Brucella melitensis biovar Canis; Brucella melitensis biovar Suis; Gram-negative bacteria; brucellosis; cattle; death; humans; neutrophils; pathogens; virulence; virulent strains
Abstract:
... Brucellosis is a globally important zoonotic infectious disease caused by gram negative bacteria of the genus Brucella. While many species of Brucella exist, Brucella melitensis, Brucella abortus, and Brucella suis are the most common pathogens of humans and livestock. The virulence of Brucella is largely influenced by its ability to evade host factors, including phagocytic killing mechanisms, whi ...
DOI:
10.1016/j.vetimm.2016.05.011

3. Acute phase protein haptoglobin as inflammatory marker in serum and synovial fluid in an equine model of arthritis

Author:
Laura Barrachina; Ana Rosa Remacha; Lourdes Soler; Natalia García; Antonio Romero; Francisco José Vázquez; Arantza Vitoria; María Ángeles Álava; Fermín Lamprave; Clementina Rodellar
Source:
Veterinary immunology and immunopathology 2016 v.182 pp. 74-78
ISSN:
0165-2427
Subject:
acute phase proteins; arthritis; blood serum; haptoglobins; horses; inflammation; models; synovial fluid
Abstract:
... Acute phase proteins are useful inflammatory markers in horses. Haptoglobin (Hp) serum level is increased in horses undergoing different inflammatory processes, including arthritis. However, Hp concentration has not been assessed in inflammatory synovial fluid (SF). The aim of the present study was to investigate the Hp response in serum and SF in horses undergoing experimentally induced arthritis ...
DOI:
10.1016/j.vetimm.2016.10.005

4. Adjuvant materials that enhance bovine γδ T cell responses

Author:
Jodi F. Hedges; Jeff Holderness; Mark A. Jutila
Source:
Veterinary immunology and immunopathology 2016 v.181 pp. 30-38
ISSN:
0165-2427
Subject:
T-lymphocytes; adjuvants; antibiotics; calves; innate immunity; livestock and meat industry; predation; respiratory tract diseases; vaccines
Abstract:
... Despite the availability of vaccines and antibiotics, viral, bacterial and parasite-induced intestinal and pulmonary diseases still cause significant losses to the livestock industry. Excepting improvements in calf survival due to predation, there have been only modest improvements in bovine calf survival since 1991. Strikingly, digestive and respiratory diseases still account for almost half of t ...
DOI:
10.1016/j.vetimm.2016.03.010
CHORUS:
10.1016/j.vetimm.2016.03.010
Chorus Open Access:
10.1016/j.vetimm.2016.03.010

5. Assessment of reference genes for reliable analysis of gene transcription by RT-qPCR in ovine leukocytes

Author:
T.A.N. Mahakapuge; J.-P.Y. Scheerlinck; C.A. Alvarez Rojas; A.L. Every; J. Hagen
Source:
Veterinary immunology and immunopathology 2016 v.171 pp. 1-6
ISSN:
0165-2427
Subject:
algorithms; genes; lymph; mononuclear leukocytes; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; sheep; transcription (genetics)
Abstract:
... With the availability of genetic sequencing data, quantitative reverse transcription PCR (RT-qPCR) is increasingly being used for the quantification of gene transcription across species. Too often there is little regard to the selection of reference genes and the impact that a poor choice has on data interpretation. Indeed, RT-qPCR provides a snapshot of relative gene transcription at a given time ...
DOI:
10.1016/j.vetimm.2015.10.010

6. Bovine WC1+ γδ T lymphocytes modify monocyte-derived macrophage responses during early Mycobacterium avium subspecies paratuberculosis infection

Author:
Monica M. Baquero; Brandon L. Plattner
Source:
Veterinary immunology and immunopathology 2016 v.170 pp. 65-72
ISSN:
0165-2427
Subject:
Mycobacterium avium subsp. paratuberculosis; T-lymphocytes; calves; coculture; direct contact; immune response; innate immunity; interferon-gamma; interleukin-10; interleukin-17; interleukin-4; macrophages; nitrites; pathogens; synergism; viability
Abstract:
... Following Mycobacterium avium subspecies paratuberculosis (Map) infection, some calves are apparently able to successfully clear the pathogen whereas others become persistently infected; however the reasons for this remain unknown. The importance of innate immunity, and in particular the role of γδ T lymphocytes, during early anti-mycobacterial immune response is recognized but specific mechanisms ...
DOI:
10.1016/j.vetimm.2015.12.002

7. Bovine natural antibodies in antibody-dependent bactericidal activity against Escherichia coli and Salmonella Typhimurium and risk of mastitis

Author:
S.E.C. van Altena; M.A. Peen; F.H. van der Linden; H.K. Parmentier; H.F.J. Savelkoul; E.J. Tijhaar
Source:
Veterinary immunology and immunopathology 2016 v.171 pp. 21-27
ISSN:
0165-2427
Subject:
Escherichia coli; Salmonella Typhimurium; antibacterial properties; antibodies; bacteria; complement; cows; immune system; immunoglobulin G; immunoglobulin M; keyhole limpet hemocyanin; lipopolysaccharides; lipoteichoic acids; mastitis; peptidoglycans; risk
Abstract:
... Natural antibodies (NAbs) are mostly IgM antibodies produced without antigenic stimulation and serve as a first line of defence of the immune system. As both natural and specific antibodies are present in animals, NAbs are studied by determining the IgM response to naïve antigens like keyhole limpet hemocyanin (KLH). In this study, we selected cows based on high and low anti-KLH IgM titers, reflec ...
DOI:
10.1016/j.vetimm.2016.01.009

8. Brucellosis vaccines for livestock

Author:
Zakia I. Goodwin; David W. Pascual
Source:
Veterinary immunology and immunopathology 2016 v.181 pp. 51-58
ISSN:
0165-2427
Subject:
Brucella; adjuvants; brucellosis; dairy products; disease reservoirs; epitopes; fetal death; genetic engineering; heterologous gene expression; hosts; immune response; livestock; livestock diseases; meat; social impact; sterilizing immunity; subunit vaccines; vaccination; vaccine development; wildlife
Abstract:
... Brucellosis is a livestock disease responsible for fetal loss due to abortions. Worldwide, this disease has profound economic and social impact by reducing the ability of livestock producers to provide an adequate supply of disease-free meat and dairy products. In addition to its presence in domesticated animals, brucellosis is harbored in a number of wildlife species creating new disease reservoi ...
DOI:
10.1016/j.vetimm.2016.03.011
CHORUS:
10.1016/j.vetimm.2016.03.011
Chorus Open Access:
10.1016/j.vetimm.2016.03.011

9. Butyric acid stimulates bovine neutrophil functions and potentiates the effect of platelet activating factor

Author:
M.D. Carretta; A.I. Hidalgo; J. Burgos; L. Opazo; L. Castro; M.A. Hidalgo; C.D. Figueroa; A. Taubert; C. Hermosilla; R.A. Burgos
Source:
Veterinary immunology and immunopathology 2016 v.176 pp. 18-27
ISSN:
0165-2427
Subject:
agonists; butyric acid; calcium; cattle; chemotaxis; digestive system; free fatty acids; gelatinase B; humans; inflammation; innate immunity; lactoferrin; mitogen-activated protein kinase; neutrophils; phospholipase C; phosphorylation; platelet-activating factor; reactive oxygen species; rodents; ruminal acidosis; second messengers; viability
Abstract:
... Increased short-chain fatty acid (SCFA) production is associated with subacute ruminal acidosis (SARA) and activation of inflammatory processes. In humans and rodents, SCFAs modulate inflammatory responses in the gut via free fatty acid receptor 2 (FFA2). In bovines, butyric acid is one of the most potent FFA2 agonists. Its expression in bovine neutrophils has recently been demonstrated, suggestin ...
DOI:
10.1016/j.vetimm.2016.05.002

10. CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis

Author:
Kohei Murakami; Shingo Maeda; Tomohiro Yonezawa; Naoaki Matsuki
Source:
Veterinary immunology and immunopathology 2016 v.182 pp. 52-58
ISSN:
0165-2427
Subject:
CCR2 receptor; antagonists; arthritis; chemoattractants; chemokine CCL2; chemokine CXCL2; chemotaxis; dogs; enzyme-linked immunosorbent assay; gene expression; humans; immunocytochemistry; interleukin-8; messenger RNA; monocytes; neutrophils; polymerase chain reaction; porosity; synovial fluid
Abstract:
... Canine idiopathic polyarthritis (IPA) is characterized by increased numbers of polymorphonuclear leukocytes (PMNs) in the synovial fluid (SF). In humans, CC chemokine ligand 2 (CCL2) and CXC chemokine ligand 8 (CXCL8) recruit monocytes and neutrophils, respectively, and are involved in various inflammatory disorders. The aim of this study was to assess the roles of these chemokines in driving PMNs ...
DOI:
10.1016/j.vetimm.2016.09.009

11. Cancer immunology and canine malignant melanoma: A comparative review

Author:
Matthew J. Atherton; Joanna S. Morris; Mark R. McDermott; Brian D. Lichty
Source:
Veterinary immunology and immunopathology 2016 v.169 pp. 15-26
ISSN:
0165-2427
Subject:
disease models; dogs; humans; immune response; immune system; medical treatment; melanoma; oral administration; plasmids; recombinant vaccines; vaccination
Abstract:
... Oral canine malignant melanoma (CMM) is a spontaneously occurring aggressive tumour with relatively few medical treatment options, which provides a suitable model for the disease in humans. Historically, multiple immunotherapeutic strategies aimed at provoking both innate and adaptive anti-tumour immune responses have been published with varying levels of activity against CMM. Recently, a plasmid ...
DOI:
10.1016/j.vetimm.2015.11.003

12. Canine placenta: A promising potential source of highly proliferative and immunomodulatory mesenchymal stromal cells?

Author:
Nathalie Saulnier; Julia Loriau; Marine Febre; Clément Robert; Rodolphe Rakic; Tancrède Bonte; Samuel Buff; Stéphane Maddens
Source:
Veterinary immunology and immunopathology 2016 v.171 pp. 47-55
ISSN:
0165-2427
Subject:
adipocytes; adipose tissue; adults; amnion; bone marrow; dogs; enzyme activity; immunomodulators; immunosuppression; indoleamine 2,3-dioxygenase; medicine; messenger RNA; phenotype; placenta; quantitative polymerase chain reaction; stromal cells; umbilical cord; veterinary medicine
Abstract:
... In veterinary medicine, therapeutic mesenchymal stromal cells (MSC) have been traditionally isolated from adult bone marrow or adipose tissue. Neonatal tissues, normally discarded at birth from all species have become an alternative source of cells for regenerative medicine in the human clinic. These cells have been described as being more primitive, proliferative and immunosuppressive than their ...
DOI:
10.1016/j.vetimm.2016.02.005

13. Capsular polysaccharide from Mycoplasma mycoides subsp. mycoides shows potential for protection against contagious bovine pleuropneumonia

Author:
Martin Mwirigi; Isabel Nkando; Moses Olum; Samuel Attah-Poku; Horace Ochanda; Emil Berberov; Andrew Potter; Volker Gerdts; Jose Perez-Casal; Hezron Wesonga; Reuben Soi; Jan Naessens
Source:
Veterinary immunology and immunopathology 2016 v.178 pp. 64-69
ISSN:
0165-2427
Subject:
Mycoplasma mycoides subsp. mycoides; adults; animal models; antibodies; cattle; contagious bovine pleuropneumonia; immunization; live vaccines; mice; ovalbumin; polysaccharides; virulence; Africa
Abstract:
... Contagious Bovine Pleuropneumonia (CBPP) is a severe respiratory disease caused by Mycoplasma mycoides subsp. mycoides (Mmm) which is widespread in Africa. The capsule polysaccharide (CPS) of Mmm is one of the few identified virulence determinants. In a previous study, immunization of mice against CPS generated antibodies, but they were not able to prevent multiplication of Mmm in this model anima ...
DOI:
10.1016/j.vetimm.2016.07.002

14. Cellular endocytic compartment localization of expressed canine CD1 molecules

Author:
Mette Schjaerff; Stefan M. Keller; Verena K. Affolter; Annemarie T. Kristensen; Peter F. Moore
Source:
Veterinary immunology and immunopathology 2016 v.182 pp. 11-21
ISSN:
0165-2427
Subject:
T-lymphocytes; antigens; confocal microscopy; dendritic cells; dogs; endosomes; genes; glycoproteins; humans; immunity; lipids; lysosomes; plasma membrane; protein synthesis; surveys
Abstract:
... CD1 molecules are glycoproteins present primarily on dendritic cells (DCs), which recognize and present a variety of foreign- and self-lipid antigens to T-cells. Humans have five different CD1 isoforms that survey distinct cellular compartments allowing for recognition of a large repertoire of lipids. The canine CD1 family consists of seven functional CD1 molecules (canine CD1a2, CD1a6, CD1a8, CD1 ...
DOI:
10.1016/j.vetimm.2016.08.012

15. Change in peripheral blood lymphocyte count in dogs following adoptive immunotherapy using lymphokine-activated T killer cells combined with palliative tumor resection

Author:
Keiichiro Mie; Terumasa Shimada; Hideo Akiyoshi; Akiyoshi Hayashi; Fumihito Ohashi
Source:
Veterinary immunology and immunopathology 2016 v.177 pp. 58-63
ISSN:
0165-2427
Subject:
T-lymphocytes; antibodies; dogs; humans; immunotherapy; interleukins; intravenous injection; lymphocyte count; neoplasms; phenotype; resection
Abstract:
... We evaluated changes in peripheral blood lymphocyte (PBL) count in dogs following adoptive immunotherapy using lymphokine-activated T killer cells (T-LAK) in combination with surgery. Fifteen tumor-bearing dogs treated with T-LAK therapy combined with palliative resection of tumors were enrolled in the present study. T-LAK were generated from autologous peripheral blood mononuclear cells (PBMC) by ...
DOI:
10.1016/j.vetimm.2016.06.007

16. Characterization and use of new monoclonal antibodies to CD11c, CD14, and CD163 to analyze the phenotypic complexity of ruminant monocyte subsets

Author:
Mahmoud M. Elnaggar; Gaber S. Abdellrazeq; Victoria Mack; Lindsay M. Fry; William C. Davis; Kun Taek Park
Source:
Veterinary immunology and immunopathology 2016 v.178 pp. 57-63
ISSN:
0165-2427
Subject:
cattle; epitopes; flow cytometry; gene expression regulation; genome; goats; granulocytes; mass spectrometry; monoclonal antibodies; monocytes; phenotype; sheep
Abstract:
... The sequencing of the bovine genome and development of mass spectrometry, in conjunction with flow cytometry (FC), have afforded an opportunity to complete the characterization of the specificity of monoclonal antibodies (mAbs), only partially characterized during previous international workshops focused on antibody development for livestock (1991, Leukocyte Antigens in Cattle, Sheep, and Goats; 1 ...
DOI:
10.1016/j.vetimm.2016.06.010

17. Characterization of host responses induced by Toll-like receptor ligands in chicken cecal tonsil cells

Author:
Khaled Taha-abdelaziz; Tamiru Negash Alkie; Douglas C. Hodgins; Bahram Shojadoost; Shayan Sharif
Source:
Veterinary immunology and immunopathology 2016 v.174 pp. 19-25
ISSN:
0165-2427
Subject:
Toll-like receptor 2; Toll-like receptor 4; bursa of Fabricius; cathelicidins; chickens; interferon-gamma; interleukin-13; interleukin-1beta; interleukin-6; intestines; ligands; lipopolysaccharides; mammals; microorganisms; oligodeoxyribonucleotides; pathogens; spleen; tonsils; vaccine adjuvants
Abstract:
... The innate responses of cecal tonsils against invading microorganisms are mediated by conserved pattern recognition receptors (PRRs) such as the Toll-like receptors (TLRs). TLRs expressed by mammalian and avian immune system cells have the capability to recognize pathogen-associated molecular patterns (PAMPs). Although, the role of TLR ligands in innate and adaptive responses in chickens has been ...
DOI:
10.1016/j.vetimm.2016.04.002

18. Colonization pattern of C. jejuni isolates of human and avian origin and differences in the induction of immune responses in chicken

Author:
Colin Pielsticker; Gerhard Glünder; Ye’ Htut Aung; Silke Rautenschlein
Source:
Veterinary immunology and immunopathology 2016 v.169 pp. 1-9
ISSN:
0165-2427
Subject:
Campylobacter jejuni; T-lymphocytes; antibodies; campylobacteriosis; cecum; chickens; food pathogens; gene expression; gene expression regulation; genotype; host-pathogen relationships; humans; immune response; immunomodulation; interferon-gamma; interleukin-6; messenger RNA; specific pathogen-free animals
Abstract:
... Campylobacter jejuni (C. jejuni) is the most frequently reported bacterial food-borne pathogen. Poultry is regarded to be the main reservoir for human campylobacteriosis. By some authors C. jejuni is considered as a commensal of the chicken gut, but clinical signs may be observed indicating host–pathogen interaction. Little is known about C. jejuni strain dependent differences in stimulation of th ...
DOI:
10.1016/j.vetimm.2015.11.005

19. Comparative analysis of the immunologic response induced by the Sterne 34F2 live spore Bacillus anthracis vaccine in a ruminant model

Author:
Okechukwu C. Ndumnego; Susanne M. Köhler; Jannie Crafford; Henriette van Heerden; Wolfgang Beyer
Source:
Veterinary immunology and immunopathology 2016 v.178 pp. 14-21
ISSN:
0165-2427
Subject:
Bacillus anthracis; Boer (goat breed); anthrax; antibodies; antigens; formaldehyde; goats; humoral immunity; immune response; immunoglobulin G; models; neutralization; neutralization tests; qualitative analysis; secondary immunization; spores; vaccination; vaccines
Abstract:
... The Sterne 34F2 live spore vaccine (SLSV) developed in 1937 is the most widely used veterinary vaccine against anthrax. However, literature on the immunogenicity of this vaccine in a target ruminant host is scarce. In this study, we evaluated the humoral response to the Bacillus anthracis protective antigen (rPA), a recombinant bacillus collagen-like protein of anthracis (rBclA), formaldehyde inac ...
DOI:
10.1016/j.vetimm.2016.06.005

20. Comparison of cytokine responses between dogs with sepsis and dogs with immune-mediated hemolytic anemia

Author:
Valerie Johnson; Brandy Burgess; Paul Morley; Ryan Bragg; Anne Avery; Steven Dow
Source:
Veterinary immunology and immunopathology 2016 v.180 pp. 15-20
ISSN:
0165-2427
Subject:
blood serum; cytokines; dogs; etiology; hemolytic anemia; immunotherapy; sepsis (infection)
Abstract:
... Cytokine abnormalities have been described previously in dogs with varied immune mediated and inflammatory conditions such as IMHA and sepsis. The purpose of this study was to establish references ranges for cytokine levels in dogs and to compare cytokine levels in normal dogs and dogs with two common inflammatory diseases (sepsis and IMHA). We hypothesized that cytokine response profiles in dogs ...
DOI:
10.1016/j.vetimm.2016.08.010