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You searched for: Journal Zeitschrift für Naturforschung Remove constraint Journal: Zeitschrift für Naturforschung Journal name Zeitschrift für Naturforschung Remove constraint Journal name: Zeitschrift für Naturforschung Subject Leucojum aestivum Remove constraint Subject: Leucojum aestivum
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1. Alkaloid Variability in Leucojum aestivum from Wild Populations

Author:
Liliya Georgievaa; Strahil Berkov; Violeta Kondakova; Jaume Bastida; Francesc Viladomat; Atanas Atanassov; Carles Codina
Source:
Zeitschrift für Naturforschung 2014 v.62 no.9-10 pp. 627-635
ISSN:
1865-7125
Subject:
Alzheimer disease; Leucojum aestivum; acetylcholinesterase; bulbs; gas chromatography-mass spectrometry; lycorine; summer; Bulgaria
Abstract:
... Leucojum aestivum (summer snowflake) is a plant species used for the extraction of galanthamine, an acetylcholinesterase inhibitor for the treatment of Alzheimer’s disease. Extracts from bulbs collected from 18 Bulgarian populations and from shoot-clumps obtained in vitro from 8 different populations showed variations in their alkaloid composition. Nineteen alkaloids were detected in the studied s ...
DOI:
10.1515/znc-2007-9-1002

2. Optimized Nutrient Medium for Galanthamine Production in Leucojum aestivum L. in vitro Shoot System

Author:
Vasil Georgiev; Strahil Berkov; Milen Georgiev; Monique Burrus; Carles Codina; Jaume Bastida; Mladenka Ilieva; Atanas Pavlov
Source:
Zeitschrift für Naturforschung 2014 v.64 no.3-4 pp. 219-224
ISSN:
1865-7125
Subject:
Leucojum aestivum; alkaloids; ammonium nitrate; ammonium sulfate; biosynthesis; potassium dihydrogen phosphate; potassium nitrate; regression analysis; sucrose
Abstract:
... The common effect of NH₄⁺, NO₃⁻, KH₂PO₄ and sucrose on the biosynthesis of galanthamine by a Leucojum aestivum shoot culture was studied. Polynominal regression models were elaborated for the description of the galanthamine biosynthesis as a consequence of variation of the investigated variables (NH₄⁺ between 0.20 and 0.54 g/L; NO₃⁻ between 1.44 and 3.44 g/L; KH₂PO₄ between 0.10 and 0.24 g/L, and ...
DOI:
10.1515/znc-2009-3-412