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You searched for: Journal name ACS Applied Materials & Interfaces Remove constraint Journal name: ACS Applied Materials & Interfaces Publication Year 2015 Remove constraint Publication Year: 2015 Subject nanoparticles Remove constraint Subject: nanoparticles Subject term genetic engineering Remove constraint Subject term: genetic engineering
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1. Genetically Programmed Clusters of Gold Nanoparticles for Cancer Cell-Targeted Photothermal Therapy

Author:
Oh Mi Hwa; Yu Jeong Heon; Kim Insu; Nam Yoon Sung
Source:
ACS Applied Materials & Interfaces 2015 v.7 no.40 pp. 22578-22586
ISSN:
1944-8252
Subject:
bacteriophages; blood serum; cell death; chemistry; coat proteins; genetic engineering; heat; irradiation; nanocarriers; nanogold; nanoparticles; neoplasm cells; prostatic neoplasms
Abstract:
... Interpretations of the interactions of nanocarriers with biological cells are often complicated by complex synthesis of materials, broad size distribution, and heterogeneous surface chemistry. Herein, the major capsid proteins of an icosahedral T7 phage (55 nm in diameter) are genetically engineered to display a gold-binding peptide and a prostate cancer cell-binding peptide in a tandem sequence. ...
DOI:
10.1021/acsami.5b07029

2. MicroRNA Replacing Oncogenic Klf4 and c-Myc for Generating iPS Cells via Cationized Pleurotus eryngii Polysaccharide-based Nanotransfection

Author:
Deng Wenwen; Cao Xia; Chen Jingjing; Zhang Zhijian; Yu Qingtong; Wang Yan; Shao Genbao; Zhou Jie; Gao Xiangdong; Yu Jiangnan; Xu Ximing
Source:
ACS Applied Materials & Interfaces 2015 v.7 no.34 pp. 18957-18966
ISSN:
1944-8252
Subject:
Pleurotus eryngii; genetic engineering; humans; induced pluripotent stem cells; medicine; microRNA; nanoparticles; particle size; physicochemical properties; plasmids; polysaccharides; transcription factors; umbilical cord
Abstract:
... Induced pluripotent stem cells (iPSCs), resulting from the forced expression of cocktails out of transcription factors, such as Oct4, Sox2, Klf4, and c-Myc (OSKM), has shown tremendous potential in regenerative medicine. Although rapid progress has been made recently in the generation of iPSCs, the safety and efficiency remain key issues for further application. In this work, microRNA 302-367 was ...
DOI:
10.1021/acsami.5b06768