Jump to Main Content
- Wang Mengke; Deng Yi; Zhou Ping; Luo Zuyuan; Li Qiuhong; Xie Bingwu; Zhang Xiaohong; Chen Tong; Pei Duanqing; Tang Zhihui; Wei Shicheng
- ACS Applied Materials & Interfaces 2015 v.7 no.8 pp. 4560-4572
- biocompatible materials; bone formation; bones; calcium; cell differentiation; chemistry; chitosan; coatings; embryonic stem cells; gene expression; humans; induced pluripotent stem cells; medicine; phosphates; somatic cells; tissue engineering; translation (genetics)
- ... Human pluripotent stem cells (hPSCs) are a promising cell source with pluripotency and capacity to differentiate into all human somatic cell types. Designing simple and safe biomaterials with an innate ability to induce osteoblastic lineage from hPSCs is desirable to realize their clinical adoption in bone regenerative medicine. To address the issue, here we developed a fully defined synthetic pep ...
- Deng Wenwen; Cao Xia; Chen Jingjing; Zhang Zhijian; Yu Qingtong; Wang Yan; Shao Genbao; Zhou Jie; Gao Xiangdong; Yu Jiangnan; Xu Ximing
- ACS Applied Materials & Interfaces 2015 v.7 no.34 pp. 18957-18966
- Pleurotus eryngii; genetic engineering; humans; induced pluripotent stem cells; medicine; microRNA; nanoparticles; particle size; physicochemical properties; plasmids; polysaccharides; transcription factors; umbilical cord
- ... Induced pluripotent stem cells (iPSCs), resulting from the forced expression of cocktails out of transcription factors, such as Oct4, Sox2, Klf4, and c-Myc (OSKM), has shown tremendous potential in regenerative medicine. Although rapid progress has been made recently in the generation of iPSCs, the safety and efficiency remain key issues for further application. In this work, microRNA 302-367 was ...