Jump to Main Content
- Silva, Lucília P. da; Pirraco, Rogério
P.; Santos, Tírcia C.; Novoa-Carballal, Ramon; Cerqueira, Mariana T.; Reis, Rui L.; Correlo, Vitor M.; Marques, Alexandra P.
- ACS Applied Materials & Interfaces 2016 v.8 no.49 pp. 33464-33474
- umbilical cord, etc ; angiogenesis; biodegradation; disaccharides; endothelial cells; gellan gum; hindlimbs; humans; hyaluronic acid; hydrogels; medicine; receptors; tissue engineering; tissue repair; Show all 14 Subjects
- ... Neovascularization has been a major challenge in many tissue regeneration strategies. Hyaluronic acid (HA) of 3–25 disaccharides is known to be angiogenic due to its interaction with endothelial cell receptors. This effect has been explored with HA-based structures but a transitory response is observed due to HA burst biodegradation. Herein we developed gellan gum (GG)-HA spongy-like hydrogels fro ...
- Wei, Dan; Sun, Jing; Bolderson, Jason; Zhong, Meiling; Dalby, Matthew John; Cusack, Maggie; Yin, Huabing; Fan, Hongsong; Zhang, Xingdong
- ACS Applied Materials & Interfaces 2017 v.9 no.17 pp. 14606-14617
- umbilical cord, etc ; alginates; bioactive properties; biomedical research; biomimetics; encapsulation; endothelial cells; humans; hydrogels; mechanical properties; models; tissue engineering; tissue repair; Show all 13 Subjects
- ... Engineering three-dimensional (3D) scaffolds with in vivo like architecture and function has shown great potential for tissue regeneration. Here we developed a facile microfluidic-based strategy for the continuous fabrication of cell-laden microfibers with hierarchically organized architecture. We show that photolithographically fabricated microfluidic devices offer a simple and reliable way to cr ...