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- Deng, Wenwen; Cao, Xia; Chen, Jingjing; Zhang, Zhijian; Yu, Qingtong; Wang, Yan; Shao, Genbao; Zhou, Jie; Gao, Xiangdong; Yu, Jiangnan; Xu, Ximing
- ACS Applied Materials & Interfaces 2015 v.7 no.34 pp. 18957-18966
- umbilical cord, etc ; Pleurotus eryngii; genetic engineering; humans; induced pluripotent stem cells; medicine; microRNA; nanoparticles; particle size; physicochemical properties; plasmids; polysaccharides; transcription factors; Show all 13 Subjects
- ... Induced pluripotent stem cells (iPSCs), resulting from the forced expression of cocktails out of transcription factors, such as Oct4, Sox2, Klf4, and c-Myc (OSKM), has shown tremendous potential in regenerative medicine. Although rapid progress has been made recently in the generation of iPSCs, the safety and efficiency remain key issues for further application. In this work, microRNA 302-367 was ...
- Silva, Lucília P. da; Pirraco, Rogério
P.; Santos, Tírcia C.; Novoa-Carballal, Ramon; Cerqueira, Mariana T.; Reis, Rui L.; Correlo, Vitor M.; Marques, Alexandra P.
- ACS Applied Materials & Interfaces 2016 v.8 no.49 pp. 33464-33474
- umbilical cord, etc ; angiogenesis; biodegradation; disaccharides; endothelial cells; gellan gum; hindlimbs; humans; hyaluronic acid; hydrogels; medicine; receptors; tissue engineering; tissue repair; Show all 14 Subjects
- ... Neovascularization has been a major challenge in many tissue regeneration strategies. Hyaluronic acid (HA) of 3–25 disaccharides is known to be angiogenic due to its interaction with endothelial cell receptors. This effect has been explored with HA-based structures but a transitory response is observed due to HA burst biodegradation. Herein we developed gellan gum (GG)-HA spongy-like hydrogels fro ...