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- Chen, Yi-Ping, et al. Show all 7 Authors
- ACS Applied Materials & Interfaces 2016 v.8 no.28 pp. 17944-17954
- silica; cell cycle checkpoints; reactive oxygen species; superoxide dismutase; cytoskeleton; glutathione peroxidase; porous media; cell membranes; nanocarriers; nanoparticles; fluorescent dyes
- ... Reactive oxygen species (ROS) are important factors in many clinical diseases. However, direct delivery of antioxidant enzymes into cells is difficult due to poor cell uptake. A proper design of delivery of enzymes by nanoparticles is very desirable for therapeutic purposes. To overcome the cell barrier problem, a designed mesoporous silica nanoparticle (MSN) system with attached TAT-fusion denatu ...