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- Diaz-San Segundo, Fayna, et al. Show all 4 Authors
- ARS USDA Submissions 2014 pp. 1
- Foot-and-mouth disease virus; Human adenovirus C; animals; cell-mediated immunity; disease prevention; foot-and-mouth disease; gene induction; genetic vectors; immune response; in vivo studies; interferons; vaccination; viral antigens; viruses
- ... Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals and causes a highly contagious disease that rapidly spreads among many susceptible species. Vaccination with an inactivated whole virus antigen in formulation with adjuvant, or with a replication-defective human adenovirus 5 (Ad5) able to deliver FMDV empty capsids have proven to be effective strategies to control disease in 7 days. ...