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- Uchida, K.
- Amino acids 2003 v.25 no.3-4 pp. 249-257
- histidine, etc ; aldehydes; lipid peroxidation; lysine; oxidation; proteins; Show all 6 Subjects
- ... Histidine and lysine are two representative targets of oxidative modifications. Histidine is extremely sensitive to a metal-catalyzed oxidation, generating 2-oxo-histidine and its ring-ruptured products, whereas the oxidation of lysine generates carbonyl products, such as aminoadipic semialdehyde. On the other hand, both histidine and lysine are nucleophilic amino acids and therefore vulnerable to ...