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You searched for: Journal name Amino acids Remove constraint Journal name: Amino acids Source 2004 v.26 no.1 Remove constraint Source: 2004 v.26 no.1 Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
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1. Evidence for the existence of hypothetical proteins in human bronchial epithelial, fibroblast, amnion, lymphocyte, mesothelial and kidney cell lines

Author:
J. E. Oh; K. Krapfenbauer; M. Fountoulakis; Th. Frischer; G. Lubec
Source:
Amino acids 2004 v.26 no.1 pp. 9-18
ISSN:
0939-4451
Subject:
amnion; antibodies; databases; digestion; fibroblasts; gel electrophoresis; genes; human cell lines; humans; kidneys; mass spectrometry; nucleotide sequences; proteins; proteome; transcription (genetics); translation (genetics)
Abstract:
... The human genome maybe limited to about 30 000 genes whereas the human proteome may be represented by a rough estimate of one million proteins. A legion of proteins have been described and information about these structures are readily available in data banks. There remains, however, a large series of unknown or hypothetical proteins (HPs). Many of them have been predicted from nucleic acid sequen ...
DOI:
10.1007/s00726-003-0060-6

2. Gender-related differences in carnosine, anserine and lysine content of murine skeletal muscle

Author:
R. Peñafiel; C. Ruzafa; F. Monserrat; A. Cremades
Source:
Amino acids 2004 v.26 no.1 pp. 53-58
ISSN:
0939-4451
Subject:
adults; anserine; carnosine; females; legs; lysine; males; mice; muscles; sexual dimorphism; skeletal muscle; testosterone
Abstract:
... The aminoacyl-imidazole dipeptides carnosine (β-alanyl-L-histidine) and anserine (β-alanyl-1-methyl-histidine) are present in relatively high concentrations in excitable tissues, such as muscle and nervous tissue. In the present study we describe the existence of a marked sexual dimorphism of carnosine and anserine in skeletal muscles of CD1 mice. In adult animals the concentrations of anserine we ...
DOI:
10.1007/s00726-003-0034-8

3. L- Histidine is a beneficial adjuvant for antiepileptic drugs against maximal electroshock-induced seizures in mice

Author:
R. M. Kamiński; D. Żółkowska; M. Kozicka; Z. Kleinrok; S. J. Czuczwar
Source:
Amino acids 2004 v.26 no.1 pp. 85-89
ISSN:
0939-4451
Subject:
histamine; histidine; isomers; laboratory animals; memory; mice; pharmacokinetics; phenytoin; protective effect; seizures
Abstract:
... Endogenous histamine has been reported to be involved in regulation of seizure susceptibility. Enhancement of histamine neurotransmission engendered by L-histidine treatment produces anticonvulsant effects in experimental animals. The present study investigated the influence of L-histidine on the protective effects of carbamazepine and phenytoin against maximal electroshock-induced seizures in mic ...
DOI:
10.1007/s00726-003-0005-0

4. Plasma amino acids and sports injuries

Author:
M. T. M. van den Baar; D. Fekkes; C. R. van den Hoogenband; H. J. Duivenvoorden; L. Pepplinkhuizen
Source:
Amino acids 2004 v.26 no.1 pp. 71-76
ISSN:
0939-4451
Subject:
glycine (amino acid); lysine; ornithine; sports; taurine; tryptophan; tyrosine
Abstract:
... The aim of this study was to explore the relationship between changes in plasma amino acids and the incidence of sports injuries during a soccer season. Fourteen plasma amino acids were assayed at monthly intervals in 12 young soccer players during a whole soccer season. Based on the number and severity of injuries the soccer players were divided into an injury-prone and a non-injury-prone group. ...
DOI:
10.1007/s00726-003-0008-x

5. Analysis of 6-hydroxy-2-aminocaproic acid (HACA) as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry

Author:
J. Pietzsch; R. Bergmann
Source:
Amino acids 2004 v.26 no.1 pp. 45-51
ISSN:
0939-4451
Subject:
amino acids; atherogenesis; copper; esters; gas chromatography; iron; low density lipoprotein; mass spectrometry; oxidation; pyridines
Abstract:
... An alteration of low density lipoprotein (LDL) apolipoprotein (apo) B-100 structure by direct oxidative modification is an important mechanism involved in atherogenesis. There is difficulty in quantifying this type of modification because a lack of specific assays. The use of N(O,S)-ethoxycarbonyl trifluoroethyl amino acid esters for a rapid and sensitive determination of 6-hydroxy-2-aminocaproic ...
DOI:
10.1007/s00726-003-0036-6

6. Effects of taurine supplementation on VDT work induced visual stress

Author:
M. Zhang; L. F. Bi; Y. D. Ai; L. P. Yang; H. B. Wang; Z. Y. Liu; M. Sekine; S. Kagamimori
Source:
Amino acids 2004 v.26 no.1 pp. 59-63
ISSN:
0939-4451
Subject:
college students; evoked potentials; males; placebos; taurine; volunteers
Abstract:
... In order to evaluate the effects of dietary taurine supplementation on visual fatigue induced by visual display terminals (VDT) work, 25 male college students aged from 20 to 24 years who were not engaged in VDT work were selected to participate in the study. Volunteers were randomly assigned to either the taurine supplementation (n=13) or the placebo supplementation control group (n=12). Before a ...
DOI:
10.1007/s00726-003-0032-x

7. Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine

Author:
M. A. Grillo; S. Colombatto
Source:
Amino acids 2004 v.26 no.1 pp. 3-8
ISSN:
0939-4451
Subject:
agmatine; animal tissues; arginine; decarboxylation; metabolism; nitric oxide; polyamines
Abstract:
... Recently agmatine, decarboxylated arginine, has been shown to be an important biological compound in several animal tissues. This paper summarizes the known information regarding the transport of arginine, its decarboxylation and the effects of the agmatine formed mainly on NO and polyamine synthesis. ...
DOI:
10.1007/s00726-003-0030-z

8. Characteristics of taurine release induced by free radicals in mouse hippocampal slices

Author:
P. Saransaari; S. S. Oja
Source:
Amino acids 2004 v.26 no.1 pp. 91-98
ISSN:
0939-4451
Subject:
adenosine; adults; agonists; antagonists; cell membranes; glutamic acid; hippocampus; hydrogen peroxide; hydroxylamine; ischemia; mice; neuroprotective effect; nitric oxide; receptors; taurine; transporters; tritium
Abstract:
... The release of the inhibitory neuromodulator taurine in the hippocampus is markedly enhanced under various neural cell-damaging conditions, including ischemia and exposure to free radicals. The properties and regulation of the release evoked by a medium containing free radicals was investigated in hippocampal slices from adult (3-month-old) and developing (7-day-old) mice, using a superfusion syst ...
DOI:
10.1007/s00726-003-0004-1

9. Evidence for expression of a single distinct form of mammalian cysteine dioxygenase

Author:
M. H. Stipanuk; M. Londono; L. L. Hirschberger; C. Hickey; D. J. Thiel; L. Wang
Source:
Amino acids 2004 v.26 no.1 pp. 99-106
ISSN:
0939-4451
Subject:
anion exchange; antibodies; brain; cysteine; dimerization; genes; kidneys; liver; mass spectrometry; molecular weight; polyacrylamide; polyacrylamide gel electrophoresis; post-translational modification; rabbits; rats
Abstract:
... Cysteine dioxygenase (CDO) plays a critical role in the regulation of cellular cysteine concentration. Because multiple forms of CDO (∼23 kDa, ∼25 kDa, and ∼68 kDa) have been claimed based upon separation and detection using SDS-PAGE/western blotting (with antibodies demonstrated to immunoprecipitate CDO), we further investigated the possibility of more than one CDO isoform. Using either rabbit an ...
DOI:
10.1007/s00726-003-0001-4

10. Fractionation of liver proteins by preparative electrophoresis

Author:
M. Fountoulakis; J.-F. Juranville; G. Tsangaris; L. Suter
Source:
Amino acids 2004 v.26 no.1 pp. 27-36
ISSN:
0939-4451
Subject:
desorption; drugs; fractionation; gels; hydrophilicity; ionization; isoelectric focusing; lithium; liver; proteins; proteomics; rats; sulfates; toxicity; toxicity testing; two-dimensional gel electrophoresis
Abstract:
... Proteomics offers unique possibilities to investigate changes in the levels and modifications of proteins involved in the pathomechanisms of diseases and toxic events. However, search for potential drug targets and disease or toxicity markers is limited by the fact that mainly the high-abundance, hydrophilic proteins are visualized in two-dimensional gels. Here we studied the enrichment of rat liv ...
DOI:
10.1007/s00726-003-0041-9

11. Immunocytochemical study by two photon fluorescence microscopy of the distribution of GABAA receptor subunits in rat cerebellar granule cells in culture

Author:
F. Merlo; R. Balduzzi; A. Cupello; M. Robello
Source:
Amino acids 2004 v.26 no.1 pp. 77-84
ISSN:
0939-4451
Subject:
cerebellum; cytoplasm; fluorescence microscopy; neurites; plasma membrane; rats
Abstract:
... An immunocytochemical investigation of the expression of α₁, α₆, β₂/₃, γ₂and δ subunits was performed on rat cerebellum granule cells in culture by the two photon microscopy technique.The first four subunits appear to be expressed abundantly in these cells, whereas the δ one seems to be expressed at a lower level. Another major difference in the distribution of these subunits is that whereas α₆, β ...
DOI:
10.1007/s00726-003-0006-z

12. Inhibition of the L-dopa transport system in human epidermal Langerhans cells by omeprazole and its analogues

Author:
N. Bendsoe; G. Ronquist
Source:
Amino acids 2004 v.26 no.1 pp. 19-26
ISSN:
0939-4451
Subject:
L-dopa; Langerhans cells; biopsy; energy; humans; plasma membrane; protons; stomach; ultrastructure
Abstract:
... L-3,4-dihydroxyphenylalanine (L-dopa) transport into human Langerhans cells (LC) occurs by a saturable mediation. This plasma membrane agency is, due to its characteristics, distinguishable from systems transporting other neutral, cationic and anionic amino acids into other cells and serves to catalyze the flow of L-dopa, only, into LC. The uphill operation of this L-dopa transport system is belie ...
DOI:
10.1007/s00726-003-0053-5

13. Myocardial taurine, development and vulnerability to ischemia

Author:
P. Modi; M.-S. Suleiman
Source:
Amino acids 2004 v.26 no.1 pp. 65-70
ISSN:
0939-4451
Subject:
children; infants; ischemia; myocardium; patients; rats; taurine
Abstract:
... Depleting intracellular taurine in heart cells improves their resistance to ischemia and reperfusion injury. The aim of this work was to see whether physiologically low levels of endogenous taurine also reflect a reduced vulnerability of the myocardium to cardiac insults. The myocardial concentration of taurine was measured during different stages of development and compared with vulnerability to ...
DOI:
10.1007/s00726-003-0031-y

14. Nitric oxide is not involved in the control of vasopressin release during acute forced swimming in rats

Author:
Mario Engelmann; G. Wolf; J Putzke; F. E. Bloom; J. Raber; R. Landgraf; M. G. Spina; T. F. W. Horn
Source:
Amino acids 2004 v.26 no.1 pp. 37-43
ISSN:
0939-4451
Subject:
blood; blood flow; citrulline; hypothalamus; in situ hybridization; messenger RNA; microdialysis; neuronal nitric oxide synthase; neurons; nitric oxide; nitrites; oxytocin; rats; secretion; swimming; vasopressin
Abstract:
... Neurons of the hypothalamo-neurohypophyseal system (HNS) are known to contain high amounts of neuronal nitric oxide (NO) synthase (nNOS). NO produced by those neurons is commonly supposed to be involved as modulator in the release of the two nonapeptides vasopressin (AVP) and oxytocin into the blood stream. Previous studies showed that forced swimming fails to increase the release of AVP into the ...
DOI:
10.1007/s00726-003-0040-x