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- Spittaels, Karl-Jan; Coenye, Tom
- Anaerobe 2018 v.49 pp. 21-29
- sebum, etc ; Propionibacterium acnes; acne; biochemical pathways; biofilm; carboxylic ester hydrolases; fluorescence microscopy; models; pathogenesis; pellets; proteinases; silicone; staining; virulence; Show all 14 Subjects
- ... The aim of the present study was to develop a new model system to study Propionibacterium acnes biofilms. This model should be representative for the conditions encountered in the pilosebaceous unit.The new model, consists of an artificial sebum pellet supported by a silicone disc. Sebum pellets were inoculated with various P. acnes strains isolated from both normal and acneic skin. Growth and bio ...