Jump to Main Content
- Fernandes, João B., et al. Show all 7 Authors
- Analytica chimica acta 2015 v.862 pp. 86-93
- analytical chemistry; biosensors; cathepsin D; drug therapy; enzymatic reactions; erythrocytes; hemoglobin; humans; hydrolysis; monitoring; parasites; quartz; screening; spectrophotometers
- ... The hemoglobin (Hb) released from erythrocytes is a primary nutritive component for many blood-feeding parasites. The aspartic protease cathepsin D is a hemoglobinase that is involved in the Hb degradation process and is considered an interesting target for chemotherapy intervention. However, traditional enzymatic assays for studying Hb degradation utilize spectrophotometric techniques, which do n ...