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You searched for: Journal Analytical and Bioanalytical Chemistry Remove constraint Journal: Analytical and Bioanalytical Chemistry Publication Year 2011 Remove constraint Publication Year: 2011 Source 2011 v.401 no.7 Remove constraint Source: 2011 v.401 no.7 Subject dimethyl sulfoxide Remove constraint Subject: dimethyl sulfoxide
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1. Development of a monoclonal antibody-based, congener-specific and solvent-tolerable direct enzyme-linked immunosorbent assay for the detection of 2,2′,4,4′-tetrabromodiphenyl ether in environmental samples.

Author:
Wang, Jia; Li, Hao; Shelver, Weilin L.; Wang, Zhanhui; Li, Qing X.; Li, Ji; Xu, Ting
Source:
Analytical and Bioanalytical Chemistry 2011 v.401 no.7 pp. 2249
ISSN:
1618-2642
Subject:
butyric acid; cross reaction; detection limit; dimethyl sulfoxide; dust; enzyme-linked immunosorbent assay; gas chromatography; haptens; mass spectrometry; metabolites; monoclonal antibodies; pollutants; polybrominated diphenyl ethers; sediment contamination; sediments; soil; soil pollution
Abstract:
... A sensitive direct enzyme-linked immunosorbent assay (ELISA) for the specific detection of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) in environmental samples was developed. A hapten mimicking BDE-47 was synthesized by introducing a butyric acid spacer into 5-hydroxy-BDE-47 and coupled to keyhole limpet hemocyanin to form an immunogen for the production of monoclonal antibodies (Mabs) against BDE ...
Handle:
10113/57635
DOI:
10.1007/s00216-011-5283-x
PubMed:
21822776