Jump to Main Content
- Xu, Liang; Tang, Cheng; Li, Xin; Li, Xiaofan; Yang, Huiping; Mao, Ruizhi; He, Jiahui; Li, Wanqing; Liu, Jiyang; Li, Yalong; Shi, Shuobo; Xiao, Xuefeng; Wang, Xianhua
- Analytical and bioanalytical chemistry 2019 v.411 no.10 pp. 1989-2000
- Angelica dahurica; Oriental traditional medicine; active ingredients; bergapten; cell membranes; cellulose; chromatography; computer simulation; confocal microscopy; databases; gamma-aminobutyric acid; gamma-aminobutyric acid receptors; image analysis; ligands; magnetism; pharmacology; screening
- ... Ligand fishing is a widely used approach for screening active compounds from natural products. Recently, cell membrane (CM) as affinity ligand has been applied in ligand fishing, including cell membrane chromatography (CMC) and CM-coated magnetic bead. However, these methods possess many weaknesses, including complicated preparation processes and time-consuming operation. In this study, cheap and ...