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- Lamani, Xolelwa; Horst, Simeon; Zimmermann, Thomas; Schmidt, Torsten C.
- Analytical and bioanalytical chemistry 2015 v.407 no.1 pp. 241-252
- acid hydrolysis; aromatic amines; biomarkers; cigarettes; derivatization; detection limit; gas chromatography-mass spectrometry; headspace analysis; humans; iodine; liquid-liquid extraction; smoke; solid phase microextraction; urine
- ... Aromatic amines are an important class of harmful components of cigarette smoke. Nevertheless, only few of them have been reported to occur in urine, which raises questions on the fate of these compounds in the human body. Here we report on the results of a new analytical method, in situ derivatization solid phase microextraction (SPME) multi-dimensional gas chromatography mass spectrometry (GCxGC ...
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