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- Zhen, Eugene Y.; Higgs, Richard E.; Gutierrez, Jesus A.
- Analytical biochemistry 2013 v.442 no.1 pp. 1-9
- biomarkers; cation exchange; detection limit; heart failure; humans; immunoassays; mass spectrometry; pH; peptides; volunteers
- ... Apelin is emerging as an important hormone regulator of cardiovascular homoeostasis and an important biomarker for heart failure. Apelin concentrations have historically been measured by immunoassays; however, reported apelin concentrations measured in healthy volunteers show a large disparity from a few picograms per milliliter (pg/ml) to several nanograms per milliliter (ng/ml). Apelin exists in ...