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You searched for: Subject "glucagon-like peptides" Remove constraint Subject: "glucagon-like peptides" Journal Analytical biochemistry Remove constraint Journal: Analytical biochemistry Publication Year 2012 Remove constraint Publication Year: 2012 Subject noninsulin-dependent diabetes mellitus Remove constraint Subject: noninsulin-dependent diabetes mellitus Subject bioassays Remove constraint Subject: bioassays Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Dynamic monitoring of β-cell injury with impedance and rescue by glucagon-like peptide-1

Author:
Guan, Ni; Gao, Weiwei; He, Min; Zheng, Min; Xu, Xiao; Wang, Xiaobo; Wang, Ming-Wei
Source:
Analytical biochemistry 2012 v.423 no.1 pp. 61-69
ISSN:
0003-2697
Subject:
glucagon-like peptide 1,   etc   ; diagnostic techniques; islets of Langerhans; monitoring; cytotoxicity; free fatty acids; hydrogen peroxide; physiology; cytokines; toxic substances; bioassays; streptozotocin; noninsulin-dependent diabetes mellitus;     Show all 13 Subjects
Abstract:
... β-Cell injury plays an important role in the development of type 1 and type 2 diabetes. Most of the β-cell bioassays depend on labeling or endpoint assessments that might not capture the true physiology or pathology of the injury process. In the current study, we dynamically detected a broad range of pathological and pharmacological responses to four toxicants (cytokine mixture, free fatty acid mi ...
DOI:
10.1016/j.ab.2012.01.014