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- Ring, Johannes, et al. Show all 9 Authors
- Analytical biochemistry 2011 v.412 no.2 pp. 134-140
- antibodies; asthma; birds; blood serum; chimerism; enzyme-linked immunosorbent assay; humans; immunoblotting; immunoglobulin E; immunoglobulin Y; monitoring; patients; therapeutics
- ... Anti-IgE therapeutics represent an efficient approach in the management of IgE-mediated allergic asthma. However, monitoring the reduction of IgE levels into a therapeutically efficient range requires the determination of residual serum IgE. We established an analytical approach to distinguish free and anti-IgE complexed serum IgE based on soluble derivatives of the human high-affinity IgE recepto ...