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You searched for: Journal Analytical chemistry Remove constraint Journal: Analytical chemistry Publication Year 2018 Remove constraint Publication Year: 2018 Source 2018 v.91 no.4 Remove constraint Source: 2018 v.91 no.4
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1. Microfluidic Adapter Converting a 96-Well Cartridge into an Autonomous Microfluidic Device

Author:
Uddin, M. Jalal; Shim, Joon S.
Source:
Analytical chemistry 2018 v.91 no.4 pp. 2686-2694
ISSN:
1520-6882
Subject:
chemical species; cross contamination; enzyme-linked immunosorbent assay; lab-on-a-chip technology; polydimethylsiloxane; thermoplastics; troponin I
Abstract:
... In this study, an immunosensing platform by integrating a single array of conventional 96-well cartridges with low-cost polydimethylsiloxane (PDMS) pillars and thermoplastic chip was designed and developed to execute enzyme-linked immunosorbent assay (ELISA). The platform provides multiple (eight) reaction chambers for sequentially detecting multiple analytes under similar assay environments. For ...
DOI:
10.1021/acs.analchem.8b04043

2. Colocalization Coefficients of a Target-Switchable Fluorescent Probe Can Serve As an Indicator of Mitochondrial Membrane Potential

Author:
Li, Xuechen; Zhang, Ruoyao; Guo, Lifang; Zhang, Huamiao; Meng, Fangfang; Yang, Rui; Li, Chuanya; Liu, Zhiqiang; Yu, Xiaoqiang
Source:
Analytical chemistry 2018 v.91 no.4 pp. 2672-2677
ISSN:
1520-6882
Subject:
fluorescence; fluorescent dyes; lysosomes; membrane potential; mitochondria; mitochondrial membrane; rhodamines; wavelengths
Abstract:
... The mitochondrial membrane potential (MMP) definitely reflects mitochondrial function. Thus, it is very essential to found a physical parameter as MMP indicator. At present, available parameters are either fluorescent intensity of monochromatic probes such as rhodamine 123 or a ratio of fluorescent intensity at different wavelengths of dual-color dyes such as JC-1, but the inconvenience in practic ...
DOI:
10.1021/acs.analchem.8b03986