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- Youn, Yeoan, et al. Show all 9 Authors
- Analytical chemistry 2017 v.89 no.4 pp. 2390-2397
- DNA; RNA-binding proteins; antigens; binding capacity; calorimetry; dissociation; glass; neoplasm cells; small nuclear RNA; spliceosomes; titration
- ... We employed modified glass nanocapillaries to investigate interactions between the RNA-binding protein, known as cell carcinoma antigen recognized by T cells-3 (SART3), and the noncoding spliceosome component, U6 small nuclear RNA (snRNA), at the single-molecule level. We functionalized the nanocapillaries with U6 snRNA fragments, which were hybridized to DNA molecules and then covalently attached ...