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- Tipton, Jeremiah D.; Tran, John C.; Catherman, Adam D.; Ahlf, Dorothy R.; Durbin, Kenneth R.; Lee, Ji Eun; Kellie, John F.; Kelleher, Neil L.; Hendrickson, Christopher L.; Marshall, Alan G.
- Analytical chemistry 2012 v.84 no.5 pp. 2111-2117
- chromatography; humans; ionization; ions; nucleotide sequences; proteins; proteome; proteomics; sequence analysis; tandem mass spectrometry; transcription (genetics)
- ... Current high-throughput top-down proteomic platforms provide routine identification of proteins less than 25 kDa with 4-D separations. This short communication reports the application of technological developments over the past few years that improve protein identification and characterization for masses greater than 25 kDa. Advances in separation science have allowed increased numbers of proteins ...
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