Journal name: Analytical chemistry / Subject term: aerosols

1. A Wide Spectral Range Photoacoustic Aerosol Absorption Spectrometer

Author:: Haisch C.; Menzenbach P.; Bladt H.; Niessner R.
Source:: Analytical chemistry 2012 v.84 no.21 pp. 8941-8945
ISSN:: 1520-6882
Subject:: absorption; aerosols; new combination; soot; spectrometers
Abstract:: ... A photoacoustic spectrometer for the measurement of aerosol absorption spectra, based on the excitation of a pulsed nanosecond optical parametrical oscillator (OPO), will be introduced. This spectrometer is working at ambient pressure and can be used to detect and characterize different classes of aerosols. The spectrometer features a spectral range of 410 to 2500 nm and a sensitivity of 2.5 × 10– ...
DOI:: 10.1021/ac302194u
: https://doi.org/10.1021/ac302194u

2. Application of Time-of-Flight Aerosol Mass Spectrometry for the Online Measurement of Gaseous Molecular Iodine

Author:: Kundel Michael; Huang Ru-Jin; Thorenz Ute R.; Bosle Janine; Mann Moritz J. D.; Ries Marco; Hoffmann Thorsten
Source:: Analytical chemistry 2012 v.84 no.3 pp. 1439-1445
ISSN:: 1520-6882
Subject:: Saccharina latissima; aerosols; alpha-cyclodextrin; detection limit; gas chromatography-mass spectrometry; gases; iodine; ozone; spectrometers
Abstract:: ... Here we present a new application of a time-of-flight aerosol mass spectrometer (TOF-AMS) for the measurement of atmospheric trace gases in real-time. Usually, TOF-AMS instruments are not sensitive to gas-phase species due to the aerodynamic particle focusing inlet system which reduces the gas phase species by a factor of about 10⁷ relative to the particle phase. This efficient removal of the gas ...
DOI:: 10.1021/ac202527a
: https://doi.org/10.1021/ac202527a

3. Chemical Analysis of Complex Organic Mixtures Using Reactive Nanospray Desorption Electrospray Ionization Mass Spectrometry

Author:: Laskin Julia; Eckert Peter A.; Roach Patrick J.; Heath Brandi S.; Nizkorodov Sergey A.; Laskin Alexander
Source:: Analytical chemistry 2012 v.84 no.16 pp. 7179-7187
ISSN:: 1520-6882
Subject:: aerosols; aldehydes; carbonyl compounds; chemical analysis; desorption; electrospray ionization mass spectrometry; ionization; limonene; oxygen; ozonolysis; solvents
Abstract:: ... Reactive nanospray desorption electrospray ionization (nano-DESI) combined with high-resolution mass spectrometry was utilized for the analysis of secondary organic aerosol produced through ozonolysis of limonene (LSOA). Previous studies have shown that LSOA constituents are multifunctional compounds containing at least one aldehyde or ketone groups. In this study, we used the selectivity of the G ...
DOI:: 10.1021/ac301533z
: https://doi.org/10.1021/ac301533z

4. Chemical Composition of Ambient Nanoparticles on a Particle-by-Particle Basis

Author:: Klems Joseph P.; Zordan Christopher A.; Pennington M. Ross; Johnston Murray V.
Source:: Analytical chemistry 2012 v.84 no.5 pp. 2253-2259
ISSN:: 1520-6882
Subject:: aerosols; algorithms; carbon; data collection; elemental composition; factor analysis; mixing; nanoparticles; nitrogen; oxidation; oxygen; spectrometers; sulfur
Abstract:: ... The nano aerosol mass spectrometer provides a quantitative measure of the elemental composition of individual, ambient nanoparticles in the 10–30 nm size range. In this work, carbon mole fraction plots are introduced as an efficient means of visualizing the full range of particle compositions in an ambient data set. These plots are constructed by plotting the composition of each particle in the da ...
DOI:: 10.1021/ac202868h
: https://doi.org/10.1021/ac202868h

5. Diode Laser Thermal Vaporization Inductively Coupled Plasma Mass Spectrometry

Author:: Foltynová Pavla; Kanický Viktor; Preisler Jan
Source:: Analytical chemistry 2012 v.84 no.5 pp. 2268-2274
ISSN:: 1520-6882
Subject:: aerosols; atomic absorption spectrometry; atomizers; blood; cadmium; cobalt; detection limit; drugs; lead; mass spectrometry; molybdenum; nickel; paper; pyrolysis; quantitative analysis; tin; volatilization; zinc
Abstract:: ... An approach of sample introduction for inductively coupled mass spectrometry (ICPMS), diode laser thermal vaporization (DLTV) is described. The method allows quantitative determination of metals in submicroliter volumes of liquid samples. Laser power is sufficient to induce pyrolysis of a suitable substrate with the deposited sample leading to aerosol generation. Unlike existing sample introductio ...
DOI:: 10.1021/ac202884m
: https://doi.org/10.1021/ac202884m

6. Direct Surface Analysis of Time-Resolved Aerosol Impactor Samples with Ultrahigh-Resolution Mass Spectrometry

Author:: Fuller Stephen J.; Zhao Yongjing; Cliff Steven S.; Wexler Anthony S.; Kalberer Markus
Source:: Analytical chemistry 2012 v.84 no.22 pp. 9858-9864
ISSN:: 1520-6882
Subject:: aerosols; atmospheric chemistry; chemical analysis; climate; drums (equipment); human health; mass spectrometry; new combination; uncertainty
Abstract:: ... Aerosol particles in the atmosphere strongly influence the Earth’s climate and human health, but the quantification of their effects is highly uncertain. The complex and variable composition of atmospheric particles is a main reason for this uncertainty. About half of the particle mass is organic material, which is very poorly characterized on a molecular level, and therefore it is challenging to ...
DOI:: 10.1021/ac3020615
: https://doi.org/10.1021/ac3020615

7. Identification of Weak and Strong Organic Acids in Atmospheric Aerosols by Capillary Electrophoresis/Mass Spectrometry and Ultra-High-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Author:: Yassine Mahmoud M.; Dabek-Zlotorzynska Ewa; Harir Mourad; Schmitt-Kopplin Philippe
Source:: Analytical chemistry 2012 v.84 no.15 pp. 6586-6594
ISSN:: 1520-6882
Subject:: aerosols; capillary electrophoresis; carboxylic acids; electrolytes; elemental composition; ionization; mass spectrometry; models; pH; particulates
Abstract:: ... A novel approach using a combination of capillary electrophoresis/mass spectrometry (CE/MS) and off-line Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS) revealed the structural details of acidic constituents of atmospheric organic aerosol. Both techniques utilized electrospray ionization (ESI), a soft ionization method, to facilitate the analysis of complex mixtures of organ ...
DOI:: 10.1021/ac300798g
: https://doi.org/10.1021/ac300798g

8. Investigation of the Chemical Mixing State of Individual Asian Dust Particles by the Combined Use of Electron Probe X-ray Microanalysis and Raman Microspectrometry

Author:: Sobanska Sophie; Hwang HeeJin; Choël Marie; Jung Hae-Jin; Eom Hyo-Jin; Kim HyeKyeong; Barbillat Jacques; Ro Chul-Un
Source:: Analytical chemistry 2012 v.84 no.7 pp. 3145-3154
ISSN:: 1520-6882
Subject:: X-radiation; aerosols; chemical composition; chemical compounds; chemical speciation; dust; dust storms; mixing; physicochemical properties; Korean Peninsula
Abstract:: ... In this work, quantitative electron probe X-ray microanalysis (EPMA) and Raman microspectrometry (RMS) were applied in combination for the first time to characterize the complex internal structure and physicochemical properties of the same ensemble of Asian dust particles. The analytical methodology to obtain the chemical composition, mixing state, and spatial distribution of chemical species with ...
DOI:: 10.1021/ac2029584
: https://doi.org/10.1021/ac2029584

9. Investigation of the Utility of Laser-Secondary Neutral Mass Spectrometry for the Detection of Polyaromatic Hydrocarbons in Individual Atmospheric Aerosol Particles

Author:: Tyler Bonnie J.; Dambach Steffen; Galla Sebastian; Peterson Richard E.; Arlinghaus Heinrich F.
Source:: Analytical chemistry 2012 v.84 no.1 pp. 76-82
ISSN:: 1520-6882
Subject:: aerosols; anthracenes; human health; ionization; mass spectrometry; naphthalene; radiative forcing; sublimation
Abstract:: ... The distribution of polyaromatic hydrocarbons (PAHs) in ambient aerosol particles is of importance to both human health and climate forcing. Although time-of-flight secondary ion mass spectrometry (ToF-SIMS) has proven useful for studying the distribution of organic compounds in individual aerosol particles, it is difficult to detect PAHs at relevant concentrations in individual aerosol particles ...
DOI:: 10.1021/ac2008338
: https://doi.org/10.1021/ac2008338

10. Microfluidic Paper-Based Analytical Device for Particulate Metals

Author:: Mentele MalloryM.; Cunningham Josephine; Koehler Kirsten; Volckens John; Henry Charles S.
Source:: Analytical chemistry 2012 v.84 no.10 pp. 4474-4480
ISSN:: 1520-6882
Subject:: aerosols; air; color; colorimetry; computer software; copper; detection limit; filters; image analysis; iron; nickel; occupational exposure; pH; rapid methods
Abstract:: ... A microfluidic paper-based analytical device (μPAD) fabricated by wax printing was designed to assess occupational exposure to metal-containing aerosols. This method employs rapid digestion of particulate metals using microliters of acid added directly to a punch taken from an air sampling filter. Punches were then placed on a μPAD, and digested metals were transported to detection reservoirs upon ...
DOI:: 10.1021/ac300309c
: https://doi.org/10.1021/ac300309c

11. Online Characterization of Particles and Gases with an Ambient Electrospray Ionization Source

Author:: Horan Andrew J.; Gao Yuqian; Hall Wiley A.; Johnston Murray V.
Source:: Analytical chemistry 2012 v.84 no.21 pp. 9253-9258
ISSN:: 1520-6882
Subject:: aerosols; alpha-pinene; atomization; cesium; dimethylamine; droplets; gases; iodides; ionization; ions; ozonolysis; reaction mechanisms; solubility; solvents; spectrometers
Abstract:: ... Methods for online characterization and quantification of gas- and particle-phase species greatly facilitate the study of aerosol particle formation and reaction mechanisms. An online method for aerosol analysis has been developed by altering a conventional electrospray ionization mass spectrometer to direct the aerosol flow through the nebulizing gas inlet. Interaction between the aerosol and ele ...
DOI:: 10.1021/ac302024y
: https://doi.org/10.1021/ac302024y

12. Optical Properties of Dispersed Aerosols in the Near Ultraviolet (355 nm): Measurement Approach and Initial Data

Author:: Ma Lulu; Thompson Jonathan E.
Source:: Analytical chemistry 2012 v.84 no.13 pp. 5611-5617
ISSN:: 1520-6882
Subject:: absorption; aerosols; alpha-pinene; ammonium sulfate; biomass; burning; dust; extinction; light scattering; ozonolysis; particle size; particulates; photometers; photooxidation; soil; spectroscopy; toluene
Abstract:: ... An aerosol albedometer combining cavity ring-down spectroscopy (CRDS) with integrating sphere nephelometry was developed for use at λ = 355 nm. The instrument measures extinction and scattering coefficients of dispersed particulate matter in the near ultraviolet (UV) spectral region. Several samples have been analyzed, including: ammonium sulfate, secondary organic aerosols (SOA) resulting from th ...
DOI:: 10.1021/ac3005814
: https://doi.org/10.1021/ac3005814

13. Quantitative Analysis of Liquids from Aerosols and Microdrops Using Laser Induced Breakdown Spectroscopy

Author:: Cahoon Erica M.; Almirall Jose R.
Source:: Analytical chemistry 2012 v.84 no.5 pp. 2239-2244
ISSN:: 1520-6882
Subject:: aerosols; aluminum; barium; calcium; correlation; detection limit; emissions; magnesium; quantitative analysis; spectrometers; spectroscopy; strontium
Abstract:: ... Laser induced breakdown spectroscopy (LIBS) is shown to be capable of low volume (90 pL) quantitative elemental analysis of picogram amounts of dissolved metals in solutions. Single-pulse and collinear double-pulse LIBS were investigated using a 532 nm dual head laser coupled to a spectrometer with an intensified charge coupled device (CCD) detector. Aerosols were produced using a micronebulizer, ...
DOI:: 10.1021/ac202834j
: https://doi.org/10.1021/ac202834j

14. Real-Time Shape-Based Particle Separation and Detailed in Situ Particle Shape Characterization

Author:: Beranek Josef; Imre Dan; Zelenyuk Alla
Source:: Analytical chemistry 2012 v.84 no.3 pp. 1459-1465
ISSN:: 1520-6882
Subject:: aerosols; ammonium sulfate; physical properties; sodium chloride; spectrometers
Abstract:: ... Particle shape is an important attribute in determining particle properties and behavior, but it is difficult to control and characterize. We present a new portable system that offers, for the first time, the ability to separate particles with different shapes and characterize their chemical and physical properties, including their dynamic shape factors (DSFs) in the transition and free-molecular ...
DOI:: 10.1021/ac202235z
: https://doi.org/10.1021/ac202235z

15. The Necessity of Microscopy to Characterize the Optical Properties of Size-Selected, Nonspherical Aerosol Particles

Author:: Veghte Daniel P.; Freedman Miriam A.
Source:: Analytical chemistry 2012 v.84 no.21 pp. 9101-9108
ISSN:: 1520-6882
Subject:: aerosols; ammonium sulfate; calcium carbonate; climate; cooling; dust; mineral content; optical properties; particle size; spectrometers; spectroscopy; transmission electron microscopy; uncertainty
Abstract:: ... It is currently unknown whether mineral dust causes a net warming or cooling effect on the climate system. This uncertainty stems from the varied and evolving shape and composition of mineral dust, which leads to diverse interactions of dust with solar and terrestrial radiation. To investigate these interactions, we have used a cavity ring-down spectrometer to study the optical properties of size- ...
DOI:: 10.1021/ac3017373
: https://doi.org/10.1021/ac3017373

16. Analytical Methodology for Determination of Organic Aerosol Functional Group Distributions

Author:: Kalafut-Pettibone Alicia J.; McGivern W. Sean
Source:: Analytical chemistry 2013 v.85 no.7 pp. 3553-3560
ISSN:: 1520-6882
Subject:: absorption; aerosols; alcohols; aldehydes; carboxylic acids; derivatization; dissociation; high performance liquid chromatography; ketones; models; oxygen; photolysis; tandem mass spectrometry; volatile organic compounds
Abstract:: ... Secondary organic aerosol (SOA) particles result from the condensation of oxidized volatile organic compounds (VOC) and consist of a complex mixture that is not conducive to complete compositional analysis. We present a simple methodology for determining the quantities of aldehydes and ketones, alcohols, and carboxylic acids in such samples via derivatization and high-performance liquid chromatogr ...
DOI:: 10.1021/ac3028728
: https://doi.org/10.1021/ac3028728

17. Calculating the Net Activity Uncertainty if the Background Includes a Nonstationary Component

Author:: Ulianov Alex; Honisch Maria; Muntener Othmar
Source:: Analytical chemistry 2013 v.85 no.5 pp. 2589-2594
ISSN:: 1520-6882
Subject:: aerosols; uncertainty; variance
Abstract:: ... Knowing the uncertainty of the net signal activity is essential in order to calculate the concentration uncertainty of an analyte in a sample or to decide whether the analyte activity is sufficient for detection. The net signal activity is usually calculated as a difference between the gross signal activity and the blank activity obtained from a material that is added to the sample during the anal ...
DOI:: 10.1021/ac302605h
: https://doi.org/10.1021/ac302605h

18. Direct Measurements of Mass-Specific Optical Cross Sections of Single-Component Aerosol Mixtures

Author:: Radney James G.; Ma Xiaofei; Gillis Keith A.; Zachariah Michael R.; Hodges Joseph T.; Zangmeister Christopher D.
Source:: Analytical chemistry 2013 v.85 no.17 pp. 8319-8325
ISSN:: 1520-6882
Subject:: absorption; aerosols; case studies; extinction; mixing; new combination; optical properties; particle size; spectrometers
Abstract:: ... The optical properties of atmospheric aerosols vary widely, being dependent upon particle composition, morphology, and mixing state. This diversity and complexity of aerosols motivates measurement techniques that can discriminate and quantify a variety of single- and multicomponent aerosols that are both internally and externally mixed. Here, we present a new combination of techniques to directly ...
DOI:: 10.1021/ac401645y
: https://doi.org/10.1021/ac401645y

19. Fast Chemical Imaging at High Spatial Resolution by Laser Ablation Inductively Coupled Plasma Mass Spectrometry

Author:: Wang Hao A. O.; Grolimund Daniel; Giesen Charlotte; Borca Camelia N.; Shaw-Stewart James R. H.; Bodenmiller Bernd; Günther Detlef
Source:: Analytical chemistry 2013 v.85 no.21 pp. 10107-10116
ISSN:: 1520-6882
Subject:: aerosols; atomic absorption spectrometry; biomarkers; breast neoplasms; diagnostic techniques; fluorescence; image analysis; laminar flow
Abstract:: ... In recent years, chemical imaging was prognosticated to become one of the key analytical applications for laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). However, moderate spatial resolution and the associated measurement time required for a larger sampling area, have restricted this versatile, high sensitivity technique from being routinely used in two-dimensional chemica ...
DOI:: 10.1021/ac400996x
: https://doi.org/10.1021/ac400996x

20. Formation of a Stable Mimic of Ambient Particulate Matter Containing Viable Infectious Respiratory Syncytial Virus and Its Dry-Deposition Directly onto Cell Cultures

Author:: Cruz-Sanchez Teresita M.; Haddrell Allen E.; Hackett Tillie L.; Singhera Gurpreet K.; Marchant David; Lekivetz Ryan; Meredith Anna; Horne Derrick; Knight Darryl A.; van Eeden Stephen F.; Bai Tony R.; Hegele Richard G.; Dorscheid Delbert R.; Agnes George R.
Source:: Analytical chemistry 2013 v.85 no.2 pp. 898-906
ISSN:: 1520-6882
Subject:: aerosols; breathing; carbon; cell culture; cell death; dry deposition; dynamins; environmental exposure; epithelial cells; epithelium; interleukin-6; interleukin-8; particulates; pathogenesis; regression analysis; respiratory tract diseases; secretion; viruses
Abstract:: ... Epidemiological associations of worse respiratory outcomes from combined exposure to ambient particulate matter (PM) and respiratory viral infection suggest possible interactions between PM and viruses. To characterize outcomes of such exposures, we developed an in vitro mimic of the in vivo event of exposure to PM contaminated with respiratory syncytial virus (RSV). Concentration of infectious RS ...
DOI:: 10.1021/ac302174y
: https://doi.org/10.1021/ac302174y

21. Halo-Shaped Flowing Atmospheric Pressure Afterglow: A Heavenly Design for Simplified Sample Introduction and Improved Ionization in Ambient Mass Spectrometry

Author:: Pfeuffer Kevin P.; Schaper J. Niklas; Shelley Jacob T.; Ray Steven J.; Chan George C. Y.; Bings Nicolas H.; Hieftje Gary M.
Source:: Analytical chemistry 2013 v.85 no.15 pp. 7512-7518
ISSN:: 1520-6882
Subject:: aerosols; atmospheric pressure; desorption; electrodes; geometry; helium; ionization; ions; mass spectrometry; protons; spectrometers; temperature; water vapor
Abstract:: ... The flowing atmospheric-pressure afterglow (FAPA) is a promising new source for atmospheric-pressure, ambient desorption/ionization mass spectrometry. However, problems exist with reproducible sample introduction into the FAPA source. To overcome this limitation, a new FAPA geometry has been developed in which concentric tubular electrodes are utilized to form a halo-shaped discharge; this geometr ...
DOI:: 10.1021/ac401524x
PubMed:: 23808829
PubMed Central:: PMC3769108
: https://doi.org/10.1021/ac401524x

22. Hydrogen Peroxide Detection in Wet Air with a Prussian Blue Based Solid Salt Bridged Three Electrode System

Author:: Komkova Maria A.; Karyakina Elena E.; Marken Frank; Karyakin Arkady A.
Source:: Analytical chemistry 2013 v.85 no.5 pp. 2574-2577
ISSN:: 1520-6882
Subject:: aerosols; air; cotton fabric; droplets; electrodes; humans; humidity; hydrogen peroxide; patients; washing
Abstract:: ... We report on a novel electroanalytical system for hydrogen peroxide (H₂O₂) detection in humidity or droplets of aerosol, formed by air bubbling through a washing chamber; the resulting flow mimics the exhaled human breath. The system is based on a planar three-electrode structure (with a Prussian Blue based H₂O₂ transducer modified working electrode) bridged by a solid salt-saturated filament mate ...
DOI:: 10.1021/ac303761h
: https://doi.org/10.1021/ac303761h

23. Ion Mobility-Mass Spectrometry with a Radial Opposed Migration Ion and Aerosol Classifier (ROMIAC)

Author:: Mui Wilton; Thomas Daniel A.; Downard Andrew J.; Beauchamp Jesse L.; Seinfeld John H.; Flagan Richard C.
Source:: Analytical chemistry 2013 v.85 no.13 pp. 6319-6326
ISSN:: 1520-6882
Subject:: aerosols; ammonium compounds; angiotensin I; angiotensin II; atmospheric pressure; bradykinin; cattle; dissociation; electric field; electrodes; ions; isomers; mass spectrometry; monitoring; spectrometers; ubiquitin
Abstract:: ... The first application of a novel differential mobility analyzer, the radial opposed migration ion and aerosol classifier (ROMIAC), is demonstrated. The ROMIAC uses antiparallel forces from an electric field and a cross-flow gas to both scan ion mobilities and continuously transmit target mobility ions with 100% duty cycle. In the ROMIAC, diffusive losses are minimized, and resolution of ions, with ...
DOI:: 10.1021/ac400580u
: https://doi.org/10.1021/ac400580u

24. Iron Isotope Composition of Particles Produced by UV-Femtosecond Laser Ablation of Natural Oxides, Sulfides, and Carbonates

Author:: d’Abzac Francois-Xavier; Beard Brian L.; Czaja Andrew D.; Konishi Hiromi; Schauer James J.; Johnson Clark M.
Source:: Analytical chemistry 2013 v.85 no.24 pp. 11885-11892
ISSN:: 1520-6882
Subject:: carbonates; gases; image analysis; isotope fractionation; electron microscopy; iron; mineral content; aerosols; models; particle size; spectroscopy; pyrite; siderite; magnetite; stable isotopes; atomization; X-radiation
Abstract:: ... The need for femtosecond laser ablation (fs-LA) systems coupled to MC-ICP-MS to accurately perform in situ stable isotope analyses remains an open question, because of the lack of knowledge concerning ablation-related isotopic fractionation in this regime. We report the first iron isotope analysis of size-resolved, laser-induced particles of natural magnetite, siderite, pyrrhotite, and pyrite, col ...
DOI:: 10.1021/ac402722t
: https://doi.org/10.1021/ac402722t

25. Light Scattering and Extinction Measurements Combined with Laser-Induced Incandescence for the Real-Time Determination of Soot Mass Absorption Cross Section

Author:: Wei Yiyi; Ma Lulu; Cao Tingting; Zhang Qing; Wu Jun; Buseck Peter R.; Thompson J. E.
Source:: Analytical chemistry 2013 v.85 no.19 pp. 9181-9188
ISSN:: 1520-6882
Subject:: absorption; aerosols; ammonium nitrate; ammonium sulfate; coatings; extinction; glycerol; kerosene; light scattering; mixing; nanospheres; relative humidity; soot; spectroscopy; statistical analysis
Abstract:: ... An aerosol albedometer was combined with laser-induced incandescence (LII) to achieve simultaneous measurements of aerosol scattering, extinction coefficient, and soot mass concentration. Frequency doubling of a Nd:YAG laser line resulted in a colinear beam of both λ = 532 and 1064 nm. The green beam was used to perform cavity ring-down spectroscopy (CRDS), with simultaneous measurements of scatte ...
DOI:: 10.1021/ac401901b
: https://doi.org/10.1021/ac401901b

26. Low-Temperature Microchip Nonaqueous Capillary Electrophoresis of Aliphatic Primary Amines: Applications to Titan Chemistry

Author:: Cable Morgan L.; Stockton Amanda M.; Mora Maria F.; Willis Peter A.
Source:: Analytical chemistry 2013 v.85 no.2 pp. 1124-1131
ISSN:: 1520-6882
Subject:: aerosols; capillary electrophoresis; chemical analysis; detection limit; ethanol; oxygen; primary amines
Abstract:: ... We demonstrate microchip nonaqueous capillary electrophoresis (μNACE) analysis of primary aliphatic amines (C1–C18) in ethanol down to −20 °C as a first step in adapting microfluidic protocols for in situ analysis on Titan. To our knowledge, this is the first report of a nonaqueous separation at −20 °C on-chip. Limits of detection (LODs) ranged from 1.0 nM to 2.6 nM, and we identified several prim ...
DOI:: 10.1021/ac3030202
: https://doi.org/10.1021/ac3030202

27. Rapid Quantification of Yeast Lipid using Microwave-Assisted Total Lipid Extraction and HPLC-CAD

Author:: Khoomrung Sakda; Chumnanpuen Pramote; Jansa-Ard Suwanee; Ståhlman Marcus; Nookaew Intawat; Borén Jan; Nielsen Jens
Source:: Analytical chemistry 2013 v.85 no.10 pp. 4912-4919
ISSN:: 1520-6882
Subject:: Saccharomyces cerevisiae; aerosols; cholesterol; chromatography; free fatty acids; hydrophilicity; microwave treatment; rapid methods; screening; solvents; triacylglycerols; yeasts
Abstract:: ... We here present simple and rapid methods for fast screening of yeast lipids in Saccharomyces cerevisiae. First we introduced a microwave-assisted technique for fast lipid extraction that allows the extraction of lipids within 10 min. The new method enhances extraction rate by 27 times, while maintaining product yields comparable to conventional methods (n = 14, P > 0.05). The recovery (n = 3) from ...
DOI:: 10.1021/ac3032405
: https://doi.org/10.1021/ac3032405

28. Real Time in Situ Chemical Characterization of Submicrometer Organic Particles Using Direct Analysis in Real Time-Mass Spectrometry

Author:: Nah Theodora; Chan ManNin; Leone Stephen R.; Wilson Kevin R.
Source:: Analytical chemistry 2013 v.85 no.4 pp. 2087-2095
ISSN:: 1520-6882
Subject:: aerosols; alcohols; aldehydes; alkanes; alkenes; amino acids; atmospheric pressure; chemical composition; desorption; esters; helium; ionization; mass spectrometry; nitrogen; oleic acid; ozone; particle size; spectrometers; surface area; temperature
Abstract:: ... Direct analysis in real time mass spectrometry (DART-MS) is used to analyze the surface chemical composition of nanometer-sized organic aerosol particles in real time at atmospheric pressure. By introducing a stream of particles in between the DART ionization source and the atmospheric pressure inlet of the mass spectrometer, the aerosol is exposed to a thermal flow of helium or nitrogen gas conta ...
DOI:: 10.1021/ac302560c
: https://doi.org/10.1021/ac302560c

29. Sampler for Collection and Analysis of Low Vapor Pressure Chemical (LVPC) Particulates/Aerosols

Author:: Ewing K. J.; Gibson D.; Sanghera J.; Miklos F.
Source:: Analytical chemistry 2013 v.85 no.20 pp. 9508-9513
ISSN:: 1520-6882
Subject:: aerosols; coatings; detectors; mass spectrometry; particulates; pesticides; silica gel; stainless steel; toxicity; vapor pressure; vapors
Abstract:: ... Detection of low vapor pressure chemicals (LVPCs) such as pesticides and other toxic/hazardous materials on various environmental surfaces as well as LVPC aerosols is a significant challenge for current vapor phase detectors. We describe a novel sampling device which utilizes stainless steel screens coated with a sticky polydimethylsiloxane coating for collecting LVPCs aerosolized off of a surface ...
DOI:: 10.1021/ac401100r
: https://doi.org/10.1021/ac401100r

30. Simultaneous Analysis of the Equilibrium Hygroscopicity and Water Transport Kinetics of Liquid Aerosol

Author:: Davies James F.; Haddrell Allen E.; Rickards Andrew M. J.; Reid Jonathan P.
Source:: Analytical chemistry 2013 v.85 no.12 pp. 5819-5826
ISSN:: 1520-6882
Subject:: aerosols; ammonium sulfate; condensation (phase transition); droplets; evaporation; galactose; gases; hygroscopicity; mass transfer; optical traps; physiological transport; prediction; relative humidity; sodium chloride; sorbitol; thermodynamics; uncertainty
Abstract:: ... We demonstrate that the equilibrium hygroscopic response of an aerosol droplet and the kinetics of water condensation and evaporation can be retrieved with high accuracy, even close to saturation, through comparative measurements of probe and sample aerosol droplets. The experimental methodology is described and is based on an electrodynamic balance with a newly designed trapping chamber. Through ...
DOI:: 10.1021/ac4005502
: https://doi.org/10.1021/ac4005502

31. Standard Addition Method for Laser Ablation ICPMS Using a Spinning Platform

Author:: Claverie Fanny; Malherbe Julien; Bier Naomi; Molloy John L.; Long Stephen E.
Source:: Analytical chemistry 2013 v.85 no.7 pp. 3584-3591
ISSN:: 1520-6882
Subject:: aerosols; atomic absorption spectrometry; barium; borates; copper; glass; isotope dilution technique; lead; lithium; mixing; nickel; sediments; soil; spinning; strontium; zinc
Abstract:: ... A method has been developed for the fast and easy determination of Pb, Sr, Ba, Ni, Cu, and Zn, which are of geological and environmental interest, in solid samples by laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS) using a spinning sample platform. The platform, containing a sample and a standard, is spun during the ablation, allowing the quasi-simultaneous ablation of both ...
DOI:: 10.1021/ac303307u
: https://doi.org/10.1021/ac303307u

32. Sub 2-μm Macroporous Silica Particles Derivatized for Enhanced Lectin Affinity Enrichment of Glycoproteins

Author:: Mann Benjamin F.; Mann Amanda K. P.; Skrabalak Sara E.; Novotny Milos V.
Source:: Analytical chemistry 2013 v.85 no.3 pp. 1905-1912
ISSN:: 1520-6882
Subject:: Aleuria; aerosols; binding capacity; blood serum; concanavalin A; glycoproteins; macropores; mass spectrometry; porous media; pyrolysis; silica; surface area; transmission electron microscopy; ultra-performance liquid chromatography; ultrasonics
Abstract:: ... A new, mechanically stable silica microparticle with macrosized internal pores (1.6 μm particles with 100 nm pores) has been developed for chromatography. The particles are characterized by an extensive network of interconnected macropores with a high intraparticle void volume, as observed by transmission electron microscopy (TEM). They are synthesized by an aerosol assembly technique called ultra ...
DOI:: 10.1021/ac303274w
PubMed:: 23278114
PubMed Central:: PMC3586544
: https://doi.org/10.1021/ac303274w

33. Wavelength-Resolved Optical Extinction Measurements of Aerosols Using Broad-Band Cavity-Enhanced Absorption Spectroscopy over the Spectral Range of 445–480 nm

Author:: Zhao Weixiong; Dong Meili; Chen Weidong; Gu Xuejun; Hu Changjin; Gao Xiaoming; Huang Wei; Zhang Weijun
Source:: Analytical chemistry 2013 v.85 no.4 pp. 2260-2268
ISSN:: 1520-6882
Subject:: absorption; aerosols; air; ammonium sulfate; latex; models; nitrogen dioxide; photoacoustic spectroscopy; polystyrenes; refractive index; wavelengths
Abstract:: ... Despite the significant progress in the measurements of aerosol extinction and absorption using spectroscopy approaches such as cavity ring-down spectroscopy (CRDS) and photoacoustic spectroscopy (PAS), the widely used single-wavelength instruments may suffer from the interferences of gases absorption present in the real environment. A second instrument for simultaneous measurement of absorbing ga ...
DOI:: 10.1021/ac303174n
: https://doi.org/10.1021/ac303174n

34. A UV–Vis Photoacoustic Spectrophotometer

Author:: Wiegand Joseph R.; Mathews L. Dalila; Smith Geoffrey D.
Source:: Analytical chemistry 2014 v.86 no.12 pp. 6049-6056
ISSN:: 1520-6882
Subject:: absorption; acetone; aerosols; detection limit; filters; gases; mercury; spectrophotometers; wavelengths
Abstract:: ... A novel photoacoustic spectrophotometer (PAS) for the measurement of gas-phase and aerosol absorption over the UV–visible region of the spectrum is described. Light from a broadband Hg arc lamp is filtered in eight separate bands from 300 to 700 nm using bandpass interference filters (centered at 301 nm, 314 nm, 364 nm, 405 nm, 436 nm, 546 nm, 578 and 687 nm) and modulated with an optical chopper ...
DOI:: 10.1021/ac501196u
: https://doi.org/10.1021/ac501196u

35. Characterization and Stability Study of Polysorbate 20 in Therapeutic Monoclonal Antibody Formulation by Multidimensional Ultrahigh-Performance Liquid Chromatography–Charged Aerosol Detection–Mass Spectrometry

Author:: Li Yi; Hewitt Daniel; Lentz Yvonne K.; Ji Junyan A.; Zhang Taylor Y.; Zhang Kelly
Source:: Analytical chemistry 2014 v.86 no.10 pp. 5150-5157
ISSN:: 1520-6882
Subject:: aerosols; anion exchange; aqueous solutions; cation exchange; drugs; esters; mass spectrometry; monoclonal antibodies; nonionic surfactants; placebos; polysorbates; protein denaturation; proteins; ultra-performance liquid chromatography
Abstract:: ... Polysorbate 20 is a nonionic surfactant commonly used in the formulation of therapeutic monoclonal antibodies (mAb) to prevent protein denaturation and aggregation. It is critical to understand the molecular heterogeneity and stability of polysorbate 20 in mAb formulations as polysorbate can gradually degrade in aqueous solution over time by multiple pathways losing surfactant functions and leadin ...
DOI:: 10.1021/ac5009628
: https://doi.org/10.1021/ac5009628

36. Cryo-Transmission Electron Microscopy Imaging of the Morphology of Submicrometer Aerosol Containing Organic Acids and Ammonium Sulfate

Author:: Veghte Daniel P.; Bittner Danielle Rae; Freedman Miriam Arak
Source:: Analytical chemistry 2014 v.86 no.5 pp. 2436-2442
ISSN:: 1520-6882
Subject:: aerosols; ammonium sulfate; atmospheric chemistry; climate; electron microscopy; ice nucleation; image analysis; optical properties; separation; solubility; succinic acid
Abstract:: ... The effects of aerosol particles on heterogeneous atmospheric chemistry and climate are determined in part by the internal arrangement of compounds within the particles. To characterize the morphology of internally mixed aerosol particles in the accumulation mode size regime, we have used cryo-transmission electron microscopy to investigate the phase separation behavior of dry, submicrometer parti ...
DOI:: 10.1021/ac403279f
: https://doi.org/10.1021/ac403279f

37. Detection of Uranium and Chemical State Analysis of Individual Radioactive Microparticles Emitted from the Fukushima Nuclear Accident Using Multiple Synchrotron Radiation X-ray Analyses

Author:: Abe Yoshinari; Iizawa Yushin; Terada Yasuko; Adachi Kouji; Igarashi Yasuhito; Nakai Izumi
Source:: Analytical chemistry 2014 v.86 no.17 pp. 8521-8525
ISSN:: 1520-6882
Subject:: X-radiation; absorption; aerosols; antimony; barium; cesium; fluorescence; fuels; glass; iron; molybdenum; nuclear power; oxidation; power plants; rubidium; tellurium; tin; uranium; zinc; zirconium
Abstract:: ... Synchrotron radiation (SR) X-ray microbeam analyses revealed the detailed chemical nature of radioactive aerosol microparticles emitted during the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, resulting in better understanding of what occurred in the plant during the early stages of the accident. Three spherical microparticles (∼2 μm, diameter) containing radioactive Cs were found in aer ...
DOI:: 10.1021/ac501998d
: https://doi.org/10.1021/ac501998d

38. Development of an Organic Lateral Resolution Test Device for Imaging Mass Spectrometry

Author:: Passarelli Melissa K.; Wang Jun; Mohammadi Amir Saeid; Trouillon Raphaël; Gilmore Ian; Ewing Andrew G.
Source:: Analytical chemistry 2014 v.86 no.19 pp. 9473-9480
ISSN:: 1520-6882
Subject:: aerosols; application methods; crystals; desorption; image analysis; ionization; lipids; mass spectrometry; polyethylene glycol; scanning electron microscopy; sublimation
Abstract:: ... An organic lateral resolution test device has been developed to measure the performance of imaging mass spectrometry (IMS) systems. The device contains periodic gratings of polyethylene glycol (PEG) and lipid bars covering a wide range of spatial frequencies. Microfabrication technologies were employed to produce well-defined chemical interfaces, which allow lateral resolution to be assessed using ...
DOI:: 10.1021/ac501228x
PubMed:: 25137365
PubMed Central:: PMC4188270
: https://doi.org/10.1021/ac501228x

39. Evaluation of Different Synchrotron Beamline Configurations for X-ray Fluorescence Analysis of Environmental Samples

Author:: Barberie Sean R.; Iceman Christopher R.; Cahill Catherine F.; Cahill Thomas M.
Source:: Analytical chemistry 2014 v.86 no.16 pp. 8253-8260
ISSN:: 1520-6882
Subject:: X-radiation; aerosols; energy; environmental assessment; filters; fluorescence
Abstract:: ... Synchrotron radiation X-ray fluorescence (SR-XRF) is a powerful elemental analysis tool, yet synchrotrons are large, multiuser facilities that are generally not amenable to modification. However, the X-ray beamlines from synchrotrons can be modified by simply including X-ray filters or removing monochromators to improve the SR-XRF analysis. In this study, we evaluated four easily applied beamline ...
DOI:: 10.1021/ac5016535
: https://doi.org/10.1021/ac5016535

40. Improving the Quantification of Secondary Organic Aerosol Using a Microflow Reactor Coupled to HPLC-MS and NMR to Manufacture Ad Hoc Calibration Standards

Author:: Finessi Emanuela; Lidster Richard T.; Whiting Fiona; Elliott Thomas; Alfarra M. Rami; McFiggans Gordon B.; Hamilton Jacqueline F.
Source:: Analytical chemistry 2014 v.86 no.22 pp. 11238-11245
ISSN:: 1520-6882
Subject:: aerosols; alpha-pinene; high performance liquid chromatography; mass spectrometry; nuclear magnetic resonance spectroscopy; oxidation; quantitative analysis
Abstract:: ... Secondary organic aerosol (SOA) is a key uncertainty in quantifying the impact of humans on Earth’s climate. SOA is a complex mixture of oxidized organic species, and a fundamental hurdle in determining its composition is the lack of authentic standards for comparison and quantification. Organic synthesis can be used to produce pure standards, but is limited to compounds for which there is a degre ...
DOI:: 10.1021/ac5028512
: https://doi.org/10.1021/ac5028512

41. Influence of Collecting Substrates on the Characterization of Hygroscopic Properties of Inorganic Aerosol Particles

Author:: Eom Hyo-Jin; Gupta Dhrubajyoti; Li Xue; Jung Hae-Jin; Kim HyeKyeong; Ro Chul-Un
Source:: Analytical chemistry 2014 v.86 no.5 pp. 2648-2656
ISSN:: 1520-6882
Subject:: Gibbs free energy; X-radiation; aerosols; aluminum foil; ammonium sulfate; contact angle; crystals; droplets; energy-dispersive X-ray analysis; glass; hydrophilicity; hydrophobicity; hygroscopicity; ions; physical properties; potassium chloride; relative humidity; silicon; silver; silver chloride; sodium chloride; spectroscopy; transmission electron microscopy
Abstract:: ... The influence of six collecting substrates with different physical properties on the hygroscopicity measurement of inorganic aerosol particle surrogates and the potential applications of these substrates were examined experimentally. Laboratory-generated single salt particles, such as NaCl, KCl, and (NH₄)₂SO₄, 1–5 μm in size, were deposited on transmission electron microscopy grids (TEM grids), pa ...
DOI:: 10.1021/ac4042075
: https://doi.org/10.1021/ac4042075

42. Measurement of Sub-2 nm Clusters of Pristine and Composite Metal Oxides during Nanomaterial Synthesis in Flame Aerosol Reactors

Author:: Fang Jiaxi; Wang Yang; Attoui Michel; Chadha Tandeep S.; Ray Jessica R.; Wang Wei-Ning; Jun Young-Shin; Biswas Pratim
Source:: Analytical chemistry 2014 v.86 no.15 pp. 7523-7529
ISSN:: 1520-6882
Subject:: aerosols; atomic force microscopy; combustion; gases; nanocomposites; nanoparticles; titanium dioxide
Abstract:: ... Measuring stable clusters to understand particle inception will aid the synthesis of well-controlled nanoparticles via gas-phase aerosol routes. Using a Half Mini differential mobility analyzer, the presence of monomers, dimers, trimers, and tetramers was detected for the first time in a flame aerosol reactor during the synthesis of pristine TiO₂ and TiO₂/SiO₂ nanocomposites. Atomic force microsco ...
DOI:: 10.1021/ac5012816
: https://doi.org/10.1021/ac5012816

43. Mechanism and Sensitivity of Anion Detection Using Rationally Designed Unsymmetrical Dications in Paired Ion Electrospray Ionization Mass Spectrometry

Author:: Xu Chengdong; Guo Hongyue; Breitbach Zachary S.; Armstrong Daniel W.
Source:: Analytical chemistry 2014 v.86 no.5 pp. 2665-2672
ISSN:: 1520-6882
Subject:: aerosols; anions; detection limit; electrospray ionization mass spectrometry; ionization; models; monitoring
Abstract:: ... Paired ion electrospray ionization (PIESI) mass spectrometry was developed as a useful technique that provides sensitive detection for anions in the positive ion mode. The ion-pairing reagent (IPR) utilized plays an essential role affecting the detection limits. This work describes the design and synthesis of two novel dications with unsymmetrical structures and their utilization for anion detecti ...
DOI:: 10.1021/ac404005v
: https://doi.org/10.1021/ac404005v

44. Method for Characterization of Low Molecular Weight Organic Acids in Atmospheric Aerosols Using Ion Chromatography Mass Spectrometry

Author:: Brent Lacey C.; Reiner Jessica L.; Dickerson Russell R.; Sander Lane C.
Source:: Analytical chemistry 2014 v.86 no.15 pp. 7328-7336
ISSN:: 1520-6882
Subject:: aerosols; aromatic acids; carbon; chemical composition; dust; inorganic salts; ion exchange chromatography; mass spectrometry; molecular weight; monitoring; particulates
Abstract:: ... The structural composition of PM2.5 monitored in the atmosphere is usually divided by the analysis of organic carbon, black (also called elemental) carbon, and inorganic salts. The characterization of the chemical composition of aerosols represents a significant challenge to analysts, and studies are frequently limited to determination of aerosol bulk properties. To better understand the potential ...
DOI:: 10.1021/ac403937e
: https://doi.org/10.1021/ac403937e

45. Total Reflection X-ray Fluorescence Analysis of Airborne Silver Nanoparticles from Fabrics

Author:: Menzel Magnus; Fittschen Ursula Elisabeth Adriane
Source:: Analytical chemistry 2014 v.86 no.6 pp. 3053-3059
ISSN:: 1520-6882
Subject:: aerosols; anti-infective properties; cleaning; detection limit; electrons; energy-dispersive X-ray analysis; fabrics; human health; lungs; nanosilver; nitric acid; nitrogen; scanning electron microscopy; silver; surface area; viruses
Abstract:: ... Ag nanoparticles (NPs) are usually applied to consumer products because of their antimicrobial properties, which are desired in fabrics for sportswear as well as cloth used for cleaning. Hazards to human health from airborne Ag NPs may occur when the NPs are inhaled. NPs are comparable in size to macromolecules and viruses and able to penetrate deep into the lungs, e.g., the alveoli, where they ma ...
DOI:: 10.1021/ac404017u
: https://doi.org/10.1021/ac404017u

46. Aerosol Analysis via Electrostatic Precipitation-Electrospray Ionization Mass Spectrometry

Author:: He Siqin; Li Lin; Duan Hongxu; Naqwi Amir; Hogan Christopher J.
Source:: Analytical chemistry 2015 v.87 no.13 pp. 6752-6760
ISSN:: 1520-6882
Subject:: aerosols; air; carbon nanoparticles; cesium; iodides; ionization; mass spectrometry; particle size; spectrometers; tungsten; volatilization
Abstract:: ... Electrospray ionization (ESI) is the preferred mode of ion generation for mass analysis of many organic species, as alternative ionization techniques can lead to appreciable analyte fragmentation. For this reason, ESI is an ideal method for the analysis of species within aerosol particles. However, because of their low concentrations (∼10 μg/m³) in most environments, ESI has been applied sparingly ...
DOI:: 10.1021/acs.analchem.5b01183
: https://doi.org/10.1021/acs.analchem.5b01183

47. Determination of the Sulfur Isotope Ratio in Carbonyl Sulfide Using Gas Chromatography/Isotope Ratio Mass Spectrometry on Fragment Ions 32S+, 33S+, and 34S+

Author:: Hattori Shohei; Toyoda Akari; Toyoda Sakae; Ishino Sakiko; Ueno Yuichiro; Yoshida Naohiro
Source:: Analytical chemistry 2015 v.87 no.1 pp. 477-484
ISSN:: 1520-6882
Subject:: aerosols; air; carbonyl sulfide; gas chromatography; ions; isotope fractionation; mass spectrometry; stable isotopes; stratosphere; sulfates; sulfur; sulfur hexafluoride; Japan
Abstract:: ... Little is known about the sulfur isotopic composition of carbonyl sulfide (OCS), the most abundant atmospheric sulfur species. We present a promising new analytical method for measuring the stable sulfur isotopic compositions (δ³³S, δ³⁴S, and Δ³³S) of OCS using nanomole level samples. The direct isotopic analytical technique consists of two parts: a concentration line and online gas chromatography ...
DOI:: 10.1021/ac502704d
: https://doi.org/10.1021/ac502704d

48. Elemental Analysis of Complex Organic Aerosol Using Isotopic Labeling and Unit-Resolution Mass Spectrometry

Author:: Hicks Raea K.; Day Douglas A.; Jimenez Jose L.; Tolbert Margaret A.
Source:: Analytical chemistry 2015 v.87 no.5 pp. 2741-2747
ISSN:: 1520-6882
Subject:: aerosols; carbon; elemental composition; isotope labeling; mass spectrometry; methane; nitrogen; photochemistry; stable isotopes
Abstract:: ... Elemental analysis of unit-mass resolution (UMR) mass spectra is limited by the amount of information available to definitively elucidate the molecular formula of a molecule ionized by electron impact. The problem is compounded when a mixture of organic molecules (such as those found in organic aerosols) is analyzed without the benefit of prior separation. For this reason, quadrupole mass spectrom ...
DOI:: 10.1021/ac504014g
: https://doi.org/10.1021/ac504014g

49. Fluorescent Sulfur-Tagged Europium(III) Coordination Polymers for Monitoring Reactive Oxygen Species

Author:: Wang Huai-Song; Bao Wen-Jing; Ren Shi-Bin; Chen Ming; Wang Kang; Xia Xing-Hua
Source:: Analytical chemistry 2015 v.87 no.13 pp. 6828-6833
ISSN:: 1520-6882
Subject:: aerosols; coordination polymers; ethanol; europium; fluorescence; fluorescent dyes; image analysis; mixing; monitoring; nanoparticles; oxidative stress; reactive oxygen species; temperature
Abstract:: ... Oxidative stress caused by reactive oxygen species (ROS) is harmful to biological systems and implicated in various diseases. A variety of selective fluorescent probes have been developed for detecting ROS to uncover their biological functions. Generally, the preparation of the fluorescent probes usually undergoes multiple synthetic steps, and the successful fluorescent sensing usually relies on t ...
DOI:: 10.1021/acs.analchem.5b01104
: https://doi.org/10.1021/acs.analchem.5b01104

50. High-Speed, High-Resolution, Multielemental Laser Ablation-Inductively Coupled Plasma-Time-of-Flight Mass Spectrometry Imaging: Part I. Instrumentation and Two-Dimensional Imaging of Geological Samples

Author:: Gundlach-Graham Alexander; Burger Marcel; Allner Steffen; Schwarz Gunnar; Wang Hao A. O.; Gyr Luzia; Grolimund Daniel; Hattendorf Bodo; Günther Detlef
Source:: Analytical chemistry 2015 v.87 no.16 pp. 8250-8258
ISSN:: 1520-6882
Subject:: aerosols; detection limit; image analysis; instrumentation; ions; isotopes; mass spectrometry; mixing
Abstract:: ... Low-dispersion laser ablation (LA) has been combined with inductively coupled plasma-time-of-flight mass spectrometry (ICP-TOFMS) to provide full-spectrum elemental imaging at high lateral resolution and fast image-acquisition speeds. The low-dispersion LA cell reported here is capable of delivering 99% of the total LA signal within 9 ms, and the prototype TOFMS instrument enables simultaneous and ...
DOI:: 10.1021/acs.analchem.5b01196
: https://doi.org/10.1021/acs.analchem.5b01196

51. High-Speed, Integrated Ablation Cell and Dual Concentric Injector Plasma Torch for Laser Ablation-Inductively Coupled Plasma Mass Spectrometry

Author:: Douglas David N.; Managh Amy J.; Reid Helen J.; Sharp Barry L.
Source:: Analytical chemistry 2015 v.87 no.22 pp. 11285-11294
ISSN:: 1520-6882
Subject:: aerosols; argon (noble gases); glass; image analysis; mass spectrometry; silica
Abstract:: ... In recent years, laser ablation-inductively coupled plasma mass spectrometry (LA-ICPMS) has gained increasing importance for biological analysis, where ultratrace imaging at micrometer resolution is required. However, while undoubtedly a valuable research tool, the washout times and sensitivity of current technology have restricted its routine and clinical application. Long periods between samplin ...
DOI:: 10.1021/acs.analchem.5b02466
: https://doi.org/10.1021/acs.analchem.5b02466

52. Investigation of a Combined Microdroplet Generator and Pneumatic Nebulization System for Quantitative Determination of Metal-Containing Nanoparticles Using ICPMS

Author:: Ramkorun-Schmidt Benita; Pergantis Spiros A.; Esteban-Fernández Diego; Jakubowski Norbert; Günther Detlef
Source:: Analytical chemistry 2015 v.87 no.17 pp. 8687-8694
ISSN:: 1520-6882
Subject:: aerosols; atomization; droplets; gold; nanoparticles; nanosilver; quantitative analysis; silver
Abstract:: ... In this work, a routinely applicable approach is presented to characterize metal NPs. Individual droplets generated from a microdroplet generator (MDG) were merged into an aerosol generated by a pneumatic nebulizer (PN) and introduced into an ICPMS. The MDG offers high transport efficiency of individual and discrete droplets and was therefore used to establish a calibration function for mass quant ...
DOI:: 10.1021/acs.analchem.5b01604
: https://doi.org/10.1021/acs.analchem.5b01604

53. Low-Temperature Plasma Ionization-Mass Spectrometry for the Analysis of Compounds in Organic Aerosol Particles

Author:: Spencer Sandra E.; Tyler Chelsea A.; Tolocka Michael P.; Glish Gary L.
Source:: Analytical chemistry 2015 v.87 no.4 pp. 2249-2254
ISSN:: 1520-6882
Subject:: aerosols; ionization; ions; mass spectrometry; polymers
Abstract:: ... Low-temperature plasma ionization, a technique that causes minimal fragmentation during ionization, is investigated as an ionization technique for mass spectrometric detection of the compounds in ambient organic aerosols in real time. The experiments presented in this paper demonstrate that ions are generated from compounds in the aerosol particles. The utility of this technique for detection of b ...
DOI:: 10.1021/ac5038889
: https://doi.org/10.1021/ac5038889

54. Mass Spectrometric Sampling of a Liquid Surface by Nanoliter Droplet Generation from Bursting Bubbles and Focused Acoustic Pulses: Application to Studies of Interfacial Chemistry

Author:: Thomas Daniel A.; Wang Lingtao; Goh Byoungsook; Kim Eun Sok; Beauchamp J. L.
Source:: Analytical chemistry 2015 v.87 no.6 pp. 3336-3344
ISSN:: 1520-6882
Subject:: aerosols; air; bubbles; droplets; humans; ionization; ions; mass spectrometry; oleic acid; oxidation; ozone; sounds; spectrometers; surface waves; surfactants; vapors
Abstract:: ... The complex chemistry occurring at the interface between liquid and vapor phases contributes significantly to the dynamics and evolution of numerous chemical systems of interest, ranging from damage to the human lung surfactant layer to the aging of atmospheric aerosols. This work presents two methodologies to eject droplets from a liquid water surface and analyze them via mass spectrometry. In bu ...
DOI:: 10.1021/ac504494t
: https://doi.org/10.1021/ac504494t

55. Measurement of Gas and Aerosol Phase Absorption Spectra across the Visible and Near-IR Using Supercontinuum Photoacoustic Spectroscopy

Author:: Radney James G.; Zangmeister Christopher D.
Source:: Analytical chemistry 2015 v.87 no.14 pp. 7356-7363
ISSN:: 1520-6882
Subject:: absorption; aerosols; databases; gases; photoacoustic spectroscopy; relative humidity; soot; spectrometers
Abstract:: ... We demonstrate a method to measure the absorption spectra of gas and aerosol species across the visible and near-IR (500 to 840 nm) using a photoacoustic (PA) spectrometer and a pulsed supercontinuum laser source. Measurements of gas phase absorption spectra were demonstrated using H₂O₍g₎ as a function of relative humidity (RH). The measured absorption intensities and peak shapes were able to be q ...
DOI:: 10.1021/acs.analchem.5b01541
: https://doi.org/10.1021/acs.analchem.5b01541

56. Miniature Flow-Through Low-Temperature Plasma Ionization Source for Ambient Ionization of Gases and Aerosols

Author:: Spencer Sandra E.; Santiago Brandon G.; Glish Gary L.
Source:: Analytical chemistry 2015 v.87 no.23 pp. 11887-11892
ISSN:: 1520-6882
Subject:: aerosols; caffeine; cellulose; gases; ionization; ions; pyrolysis
Abstract:: ... The design and operation of an inexpensive, miniature low-temperature plasma ion source is detailed. The miniature low-temperature plasma ion source is operated in a “flow-through” configuration, wherein the gaseous or aerosolized analyte, caffeine or pyrolyzed ethyl cellulose, in a carrier gas is used as the plasma gas. In this flow-through configuration, the sensitivity for the caffeine standard ...
DOI:: 10.1021/acs.analchem.5b03447
: https://doi.org/10.1021/acs.analchem.5b03447

57. Online Analysis of Single Cyanobacteria and Algae Cells under Nitrogen-Limited Conditions Using Aerosol Time-of-Flight Mass Spectrometry

Author:: Cahill John F.; Darlington Thomas K.; Fitzgerald Christine; Schoepp Nathan G.; Beld Joris; Burkart MichaelD.; Prather Kimberly A.
Source:: Analytical chemistry 2015 v.87 no.16 pp. 8039-8046
ISSN:: 1520-6882
Subject:: Chlamydomonas reinhardtii; Cyanobacteria; aerosols; algae; atomization; cell membranes; chemistry; chloroplasts; image analysis; lipids; mass spectrometry; metabolomics; nitrogen; rapid methods; spectrometers
Abstract:: ... Metabolomics studies typically perform measurements on populations of whole cells which provide the average representation of a collection of many cells. However, key mechanistic information can be lost using this approach. Investigating chemistry at the single cell level yields a more accurate representation of the diversity of populations within a cell sample; however, this approach has many ana ...
DOI:: 10.1021/acs.analchem.5b02326
: https://doi.org/10.1021/acs.analchem.5b02326

58. Radial Diffusion and Penetration of Gas Molecules and Aerosol Particles through Laminar Flow Reactors, Denuders, and Sampling Tubes

Author:: Knopf Daniel A.; Pöschl Ulrich; Shiraiwa Manabu
Source:: Analytical chemistry 2015 v.87 no.7 pp. 3746-3754
ISSN:: 1520-6882
Subject:: aerosols; chemical analysis; engineering; equations; gases; laminar flow; ozone; physical chemistry; prediction; reaction kinetics
Abstract:: ... Flow reactors, denuders, and sampling tubes are essential tools for many applications in analytical and physical chemistry and engineering. We derive a new method for determining radial diffusion effects and the penetration or transmission of gas molecules and aerosol particles through cylindrical tubes under laminar flow conditions using explicit analytical equations. In contrast to the tradition ...
DOI:: 10.1021/ac5042395
: https://doi.org/10.1021/ac5042395

59. Single-Particle Time-of-Flight Mass Spectrometry Utilizing a Femtosecond Desorption and Ionization Laser

Author:: Zawadowicz Maria A.; Abdelmonem Ahmed; Mohr Claudia; Saathoff Harald; Froyd Karl D.; Murphy Daniel M.; Leisner Thomas; Cziczo Daniel J.
Source:: Analytical chemistry 2015 v.87 no.24 pp. 12221-12229
ISSN:: 1520-6882
Subject:: aerosols; air; ammonium nitrate; desorption; heavy metals; ionization; ions; lasers; lead; mass spectrometry; mixing; sodium chloride; spectrometers; wavelengths
Abstract:: ... Single-particle time-of-flight mass spectrometry has now been used since the 1990s to determine particle-to-particle variability and internal mixing state. Instruments commonly use 193 nm excimer or 266 nm frequency-quadrupled Nd:YAG lasers to ablate and ionize particles in a single step. We describe the use of a femtosecond laser system (800 nm wavelength, 100 fs pulse duration) in combination wi ...
DOI:: 10.1021/acs.analchem.5b03158
: https://doi.org/10.1021/acs.analchem.5b03158

60. Speciation Analysis of 129I and 127I in Aerosols Using Sequential Extraction and Mass Spectrometry Detection

Author:: Zhang Luyuan; Hou Xiaolin; Xu Sheng
Source:: Analytical chemistry 2015 v.87 no.13 pp. 6937-6944
ISSN:: 1520-6882
Subject:: aerosols; chromatography; filters; heat; iodates; iodides; iodine; isotopes; leaching; mass spectrometry; oxidation; polypropylenes; radionuclides; sodium hydroxide; temperature; Denmark
Abstract:: ... A new analytical method has been developed for speciation analysis of ¹²⁷I and ¹²⁹I in aerosols collected on polypropylene (PP) filter paper. Iodide, iodate, NaOH soluble iodine, and insoluble iodine were separated from aerosols using sequential extraction, chromatography separation, and alkaline ashing and measured using inductive coupled plasma mass spectrometry (ICP-MS) for ¹²⁷I and accelerator ...
DOI:: 10.1021/acs.analchem.5b01555
: https://doi.org/10.1021/acs.analchem.5b01555

61. Surface Enhanced Raman Spectroscopy Enables Observations of Previously Undetectable Secondary Organic Aerosol Components at the Individual Particle Level

Author:: Craig Rebecca L.; Bondy Amy L.; Ault Andrew P.
Source:: Analytical chemistry 2015 v.87 no.15 pp. 7510-7514
ISSN:: 1520-6882
Subject:: Raman spectroscopy; aerosols; oxidation; silver; volatile organic compounds
Abstract:: ... The first use of surface enhanced Raman spectroscopy (SERS) to detect trace organic and/or inorganic species in ambient atmospheric aerosol particles is presented. This new analytical method provides direct, spectroscopic detection of species present at attogram to femtogram levels in individual submicrometer atmospheric particles. An array of spectral features resulting from organic functional gr ...
DOI:: 10.1021/acs.analchem.5b01507
: https://doi.org/10.1021/acs.analchem.5b01507

62. “Wave” Signal-Smoothing and Mercury-Removing Device for Laser Ablation Quadrupole and Multiple Collector ICPMS Analysis: Application to Lead Isotope Analysis

Author:: Hu Zhaochu; Zhang Wen; Liu Yongsheng; Gao Shan; Li Ming; Zong Keqing; Chen Haihong; Hu Shenghong
Source:: Analytical chemistry 2015 v.87 no.2 pp. 1152-1157
ISSN:: 1520-6882
Subject:: aerosols; fractionation; isotopes; lead; mercury; sulfides
Abstract:: ... A novel “wave” signal-smoothing and mercury-removing device has been developed for laser ablation quadrupole and multiple collector ICPMS analysis. With the wave stabilizer that has been developed, the signal stability was improved by a factor of 6.6–10 and no oscillation of the signal intensity was observed at a repetition rate of 1 Hz. Another advantage of the wave stabilizer is that the signal ...
DOI:: 10.1021/ac503749k
: https://doi.org/10.1021/ac503749k

63. Abundance and Impact of Doubly Charged Polyatomic Argon Interferences in ICPMS Spectra

Author:: Hattendorf Bodo; Gusmini Bianca; Dorta Ladina; Houk Robert S.; Günther Detlef
Source:: Analytical chemistry 2016 v.88 no.14 pp. 7281-7288
ISSN:: 1520-6882
Subject:: aerosols; argon (noble gases); calcium; copper; dissociation; ions; isotopes; spectrometers; strontium; temperature; zinc
Abstract:: ... Doubly charged molecular ions of alkaline earth metals and argon could be identified as spectral interferences in an inductively coupled plasma mass spectrometer. These molecular ions were found to occur at abundances reaching about 10–⁴ relative to the alkaline earth atomic ion abundances. They can thus substantially affect ultratrace analyses and, when present at similar concentration as the ana ...
DOI:: 10.1021/acs.analchem.6b01614
: https://doi.org/10.1021/acs.analchem.6b01614

64. Characterization of Highly Oxidized Molecules in Fresh and Aged Biogenic Secondary Organic Aerosol

Author:: Tu Peijun; Hall Wiley A.; Johnston Murray V.
Source:: Analytical chemistry 2016 v.88 no.8 pp. 4495-4501
ISSN:: 1520-6882
Subject:: aerosols; alpha-pinene; beta-pinene; carbon; elemental composition; gases; hydroxyl radicals; limonene; mass spectrometry; mixing; oxidation; ozone
Abstract:: ... In this work, highly oxidized multifunctional molecules (HOMs) in fresh and aged secondary organic aerosol (SOA) derived from biogenic precursors are characterized with high-resolution mass spectrometry. Fresh SOA was generated by mixing ozone with a biogenic precursor (β-pinene, limonene, α-pinene) in a flow tube reactor. Aging was performed by passing the fresh SOA through a photochemical reacto ...
DOI:: 10.1021/acs.analchem.6b00378
PubMed:: 27000653
PubMed Central:: PMC4924475
: https://doi.org/10.1021/acs.analchem.6b00378

65. Compositional Analysis of Aerosols Using Calibration-Free Laser-Induced Breakdown Spectroscopy

Author:: Boudhib Mohamed; Hermann Jörg; Dutouquet Christophe
Source:: Analytical chemistry 2016 v.88 no.7 pp. 4029-4035
ISSN:: 1520-6882
Subject:: aerosols; aluminum oxide; elemental composition; glass; helium; ions; spectrometers; spectroscopy; thermodynamics; vapors
Abstract:: ... We demonstrate that the elemental composition of aerosols can be measured using laser-induced breakdown spectroscopy (LIBS) without any preliminary calibration with standard samples. Therefore, a nanosecond Nd:YAG laser beam was focused into a flux of helium charged with alumina aerosols of a few micrometers diameter. The emission spectrum of the laser-generated breakdown plasma was recorded with ...
DOI:: 10.1021/acs.analchem.6b00329
: https://doi.org/10.1021/acs.analchem.6b00329

66. Liquid Nebulization–Ion Mobility Spectrometry Based Quantification of Nanoparticle–Protein Conjugate Formation

Author:: Jeon Seongho; Oberreit Derek R.; Van Schooneveld Gary; Hogan Christopher J.
Source:: Analytical chemistry 2016 v.88 no.15 pp. 7667-7674
ISSN:: 1520-6882
Subject:: aerosols; atomization; bovine serum albumin; gases; gold; light scattering; nanogold; nanoparticles; quartz; spectroscopy; statistical analysis
Abstract:: ... Despite the importance of examining the formation of nanoparticle–protein conjugates, there is a dearth of routine techniques for nanoparticle–protein conjugate characterization. The most prominent change to a nanoparticle population upon conjugate formation is a shift in the nanoparticle size distribution function. However, commonly employed dynamic light scattering based approaches for size dist ...
DOI:: 10.1021/acs.analchem.6b01555
: https://doi.org/10.1021/acs.analchem.6b01555

67. Novel Image Metrics for Retrieval of the Lateral Resolution in Line Scan-Based 2D LA-ICPMS Imaging via an Experimental-Modeling Approach

Author:: van Elteren Johannes Teun; Izmer Andrei; Šelih Vid Simon; Vanhaecke Frank
Source:: Analytical chemistry 2016 v.88 no.14 pp. 7413-7420
ISSN:: 1520-6882
Subject:: aerosols; databases; image analysis; systems engineering
Abstract:: ... The quality of elemental image maps obtained via line scan-based LA-ICPMS is a function of the temporal response of the entire system, governed by the design of the system and mapping and acquisition conditions used, next to the characteristics of the sample. To quantify image degradation, ablation targets with periodic gratings are required for the construction of a modulation transfer function ( ...
DOI:: 10.1021/acs.analchem.6b02052
: https://doi.org/10.1021/acs.analchem.6b02052

68. Preconcentration and Atomization of Arsane in a Dielectric Barrier Discharge with Detection by Atomic Absorption Spectrometry

Author:: Novák Petr; Dědina Jiří; Kratzer Jan
Source:: Analytical chemistry 2016 v.88 no.11 pp. 6064-6070
ISSN:: 1520-6882
Subject:: aerosols; air; antimony; arsenic; atomic absorption spectrometry; atomization; atomizers; detection limit; helium; hydrogen; nitrogen; oxygen; quartz; selenium; sodium hydroxide
Abstract:: ... Atomization of arsane in a 17 W planar quartz dielectric barrier discharge (DBD) atomizer was optimized, and its performance was compared to that of a multiple microflame quartz tube atomizer (MMQTA) for atomic absorption spectrometry (AAS). Argon, at a flow rate of 60 mL min–¹, was the best DBD discharge gas. Free As atoms were also observed in the DBD with nitrogen, hydrogen, and helium discharg ...
DOI:: 10.1021/acs.analchem.6b01365
: https://doi.org/10.1021/acs.analchem.6b01365

69. Quantifying the Hygroscopic Growth of Individual Submicrometer Particles with Atomic Force Microscopy

Author:: Morris Holly S.; Estillore Armando D.; Laskina Olga; Grassian Vicki H.; Tivanski Alexei V.
Source:: Analytical chemistry 2016 v.88 no.7 pp. 3647-3654
ISSN:: 1520-6882
Subject:: aerosols; atomic force microscopy; climate; growth factors; malonic acid; pelargonic acid; relative humidity; sodium chloride
Abstract:: ... The water uptake behavior of atmospheric aerosol dictates their climate effects. In many studies, aerosol particles are deposited onto solid substrates to measure water uptake; however, the effects of the substrate are not well understood. Furthermore, in some cases, methods used to analyze and quantify water uptake of substrate deposited particles use a two-dimensional (2D) analysis to monitor gr ...
DOI:: 10.1021/acs.analchem.5b04349
: https://doi.org/10.1021/acs.analchem.5b04349

70. Raman Spectroscopy of Isotopic Water Diffusion in Ultraviscous, Glassy, and Gel States in Aerosol by Use of Optical Tweezers

Author:: Davies James F.; Wilson Kevin R.
Source:: Analytical chemistry 2016 v.88 no.4 pp. 2361-2366
ISSN:: 1520-6882
Subject:: Raman spectroscopy; aerosols; citric acid; diffusivity; droplets; equations; gels; magnesium sulfate; mass transfer; mathematical theory; mixing; optical traps; prediction; relative humidity; shikimic acid; sucrose; water activity
Abstract:: ... The formation of ultraviscous, glassy, and amorphous gel states in aqueous aerosol following the loss of water results in nonequilibrium dynamics due to the extended time scales for diffusive mixing. Existing techniques for measuring water diffusion by isotopic exchange are limited by contact of samples with the substrate, and methods applied to infer diffusion coefficients from mass transport in ...
DOI:: 10.1021/acs.analchem.5b04315
: https://doi.org/10.1021/acs.analchem.5b04315

71. Real-Time, Online Automated System for Measurement of Water-Soluble Reactive Phosphate Ions in Atmospheric Particles

Author:: Violaki Kalliopi; Fang Ting; Mihalopoulos Nikos; Weber Rodney; Nenes Athanasios
Source:: Analytical chemistry 2016 v.88 no.14 pp. 7163-7170
ISSN:: 1520-6882
Subject:: aerosols; atmospheric chemistry; chemistry; detection limit; fiber optics; instrumentation; ions; molybdenum; phosphates; spectrometers; tin; wavelengths
Abstract:: ... We present a novel automated system for real-time measurements of water-soluble reactive phosphate (SRP) ions in atmospheric particles. Detection of SRP is based on molybdenum blue chemistry with Sn(II) chloride dihydrate reduction. The instrumentation consists of one particle-into-liquid sampler (PILS) coupled with a 250 cm path length liquid waveguide capillary cell (LWCC) and miniature fiber op ...
DOI:: 10.1021/acs.analchem.6b01264
: https://doi.org/10.1021/acs.analchem.6b01264

72. Simultaneous Preconcentration and Desalting of Organic Solutes in Aqueous Solutions by Bubble Bursting

Author:: Chingin Konstantin; Cai Yunfeng; Liang Juchao; Chen Huanwen
Source:: Analytical chemistry 2016 v.88 no.10 pp. 5033-5036
ISSN:: 1520-6882
Subject:: aerosols; aqueous solutions; bubbles; chromatography; mass spectrometry; organic compounds; solutes
Abstract:: ... Significant efforts are being made to develop more practical and versatile approaches for the preconcentration and purification of complex chemical samples. Inspired by the naturally occurring enrichment of organic compounds in sea aerosols, in this study we demonstrate the potential of induced bubble bursting as an approach for the preconcentration of organic solutes in various aqueous solutions. ...
DOI:: 10.1021/acs.analchem.6b00582
: https://doi.org/10.1021/acs.analchem.6b00582

73. Speciation of Nitrogen-Bearing Species Using Negative and Positive Secondary Ion Spectra with Nano Secondary Ion Mass Spectrometry

Author:: Li Kexue; Sinha Baerbel; Hoppe Peter
Source:: Analytical chemistry 2016 v.88 no.6 pp. 3281-3288
ISSN:: 1520-6882
Subject:: aerosols; amino acids; ammonium salts; carbon; ions; mass spectrometry; nitrates; nitrites; nitrogen; nitrogen dioxide; organic acids and salts; oxygen; quantitative analysis; stable isotopes; sugars; triazines; urea
Abstract:: ... In this study, we demonstrate that Nano Secondary Ion Mass Spectrometry (NanoSIMS) can be used to differentiate different nitrogen-containing species commonly observed in atmospheric aerosol particles with micrometer or submicrometer spatial resolution, on the basis of the relative intensity of secondary ion signals, both in negative and positive secondary ion mode, without the need to chemically ...
DOI:: 10.1021/acs.analchem.5b04740
: https://doi.org/10.1021/acs.analchem.5b04740

74. Tip-Enhanced Raman Spectroscopy of Atmospherically Relevant Aerosol Nanoparticles

Author:: Ofner Johannes; Deckert-Gaudig Tanja; Kamilli Katharina A.; Held Andreas; Lohninger Hans; Deckert Volker; Lendl Bernhard
Source:: Analytical chemistry 2016 v.88 no.19 pp. 9766-9772
ISSN:: 1520-6882
Subject:: Raman spectroscopy; aerosols; climate; nanoparticles
Abstract:: ... Atmospheric aerosol nanoparticles play a major role in many atmospheric processes and in particular in the global climate system. Understanding their formation by homogeneous or heterogeneous nucleation as well as their photochemical aging and atmospheric transformation is of utmost importance to evaluate their impact on atmospheric phenomena. Single particle analysis like tip-enhanced Raman spect ...
DOI:: 10.1021/acs.analchem.6b02760
: https://doi.org/10.1021/acs.analchem.6b02760

75. Aerosol Mass Spectrometer for Simultaneous Detection of Polyaromatic Hydrocarbons and Inorganic Components from Individual Particles

Author:: Passig Johannes; Schade Julian; Oster Markus; Fuchs Matthias; Ehlert Sven; Jäger Cornelia; Sklorz Martin; Zimmermann Ralf
Source:: Analytical chemistry 2017 v.89 no.12 pp. 6341-6345
ISSN:: 1520-6882
Subject:: aerosols; air pollution; climate; combustion; desorption; ionization; ions; mixing; polycyclic aromatic hydrocarbons; risk; spectrometers
Abstract:: ... Online studies of single airborne particles represent a demanding challenge in aerosol chemistry. New technologies that help to unravel the role of ambient aerosols in earth climate and to assess local and specific health risks from air pollution are highly desired. Of particular relevance are polycyclic aromatic hydrocarbons (PAHs) from combustion processes that are associated with both acute and ...
DOI:: 10.1021/acs.analchem.7b01207
: https://doi.org/10.1021/acs.analchem.7b01207

76. Aerosol-Phase Extraction Method for Determination of Ca, K, Mg, and Na in Biodiesel through Inductively Coupled Plasma Optical Emission Spectrometry

Author:: Raquel Sánchez; Salvador Maestre; Soledad Prats; José-Luis Todolí
Source:: Analytical chemistry 2017 v.89 no.24 pp. 13618-13625
ISSN:: 1520-6882
Subject:: aerosols; aqueous solutions; atomic absorption spectrometry; atomization; biodiesel; calcium; detection limit; digestion; droplets; emulsions; liquid-liquid extraction; liquids; magnesium; nitric acid; potassium; sodium; surface area; uncertainty
Abstract:: ... A novel extraction method was developed, optimized, and validated for the elemental analysis of organic samples. The method, called aerosol-phase extraction (APE), is based on nebulization of the extracting aqueous solution (0.1 mol·L–¹ nitric acid) on the sample. Extraction was performed at the interface of generated extractant droplets as they entered into contact with the samples. Afterward, th ...
DOI:: 10.1021/acs.analchem.7b04205
: https://doi.org/10.1021/acs.analchem.7b04205

77. Atomic Force Microscopy-Infrared Spectroscopy of Individual Atmospheric Aerosol Particles: Subdiffraction Limit Vibrational Spectroscopy and Morphological Analysis

Author:: Bondy Amy L.; Kirpes Rachel M.; Merzel Rachel L.; Pratt Kerri A.; Banaszak Holl Mark M.; Ault Andrew P.
Source:: Analytical chemistry 2017 v.89 no.17 pp. 8594-8598
ISSN:: 1520-6882
Subject:: absorption; aerosols; ammonium sulfate; atomic force microscopy; biochemical polymorphism; chemical analysis; climate; image analysis; infrared spectroscopy; models; photons; sodium nitrate; succinic acid; sucrose; viscosity; water uptake
Abstract:: ... Chemical analysis of atmospheric aerosols is an analytical challenge, as aerosol particles are complex chemical mixtures that can contain hundreds to thousands of species in attoliter volumes at the most abundant sizes in the atmosphere (∼100 nm). These particles have global impacts on climate and health, but there are few methods available that combine imaging and the detailed molecular informati ...
DOI:: 10.1021/acs.analchem.7b02381
: https://doi.org/10.1021/acs.analchem.7b02381

78. Characterization of the Aerosol-Based Synthesis of Uranium Particles as a Potential Reference Material for Microanalytical Methods

Author:: Middendorp R.; Dürr M.; Knott A.; Pointurier F.; Ferreira Sanchez D.; Samson V.; Grolimund D.
Source:: Analytical chemistry 2017 v.89 no.8 pp. 4721-4728
ISSN:: 1520-6882
Subject:: aerosols; chemical composition; droplets; forensic sciences; heat treatment; mass spectrometry; pyrolysis; uranium
Abstract:: ... A process for production of micrometer-sized particles composed of uranium oxide using aerosol spray pyrolysis is characterized with respect to the various production parameters. The aerosol is generated using a vibrating orifice aerosol generator providing monodisperse droplets, which are oxidized in a subsequent heat treatment. The final particles are characterized with microanalytical methods t ...
DOI:: 10.1021/acs.analchem.7b00631
: https://doi.org/10.1021/acs.analchem.7b00631

79. Coalescence Sampling and Analysis of Aerosols using Aerosol Optical Tweezers

Author:: Haddrell Allen E.; Miles Rachael E. H.; Bzdek Bryan R.; Reid Jonathan P.; Hopkins Rebecca J.; Walker Jim S.
Source:: Analytical chemistry 2017 v.89 no.4 pp. 2345-2352
ISSN:: 1520-6882
Subject:: Raman spectroscopy; aerosols; optical traps; refractive index; statistical analysis
Abstract:: ... We present a first exploratory study to assess the use of aerosol optical tweezers as an instrument for sampling and detecting accumulation- and coarse-mode aerosol. A subpicoliter aqueous aerosol droplet is captured in the optical trap and used as a sampling volume, accreting mass from a free-flowing aerosol generated by a medical nebulizer or atomizer. Real-time measurements of the initial stabi ...
DOI:: 10.1021/acs.analchem.6b03979
: https://doi.org/10.1021/acs.analchem.6b03979

80. Direct Analysis of Aerosolized Chemical Warfare Simulants Captured on a Modified Glass-Based Substrate by “Paper-Spray” Ionization

Author:: Dhummakupt Elizabeth S.; Mach Phillip M.; Carmany Daniel; Demond Paul S.; Moran Theodore S.; Connell Theresa; Wylie Harold S.; Manicke Nicholas E.; Nilles J. Michael; Glaros Trevor
Source:: Analytical chemistry 2017 v.89 no.20 pp. 10866-10872
ISSN:: 1520-6882
Subject:: aerosols; air; air flow; ammonium sulfate; detection limit; filters; glass fibers; ionization; mass spectrometry; paper; phosphates
Abstract:: ... Paper spray ionization mass spectrometry offers a rapid alternative platform requiring no sample preparation. Aerosolized chemical warfare agent (CWA) simulants trimethyl phosphate, dimethyl methylphosphonate, and diisopropyl methylphosphonate were captured by passing air through a glass fiber filter disk within a disposable paper spray cartridge. CWA simulants were aerosolized at varying concentr ...
DOI:: 10.1021/acs.analchem.7b02530
: https://doi.org/10.1021/acs.analchem.7b02530

81. Direct Online Determination of Laser-Induced Particle Size Distribution by ICPMS

Author:: Donard Ariane; Claverie Fanny; Pointurier Fabien; Blitz Frayret Céline; Svatosova Barbora; Pécheyran Christophe
Source:: Analytical chemistry 2017 v.89 no.17 pp. 8791-8799
ISSN:: 1520-6882
Subject:: detection limit; copper; foil; aerosols; particle size; particle size distribution; computer software; atomic absorption spectrometry; information processing; nanoparticles
Abstract:: ... The characterization of the aerosol (size, composition, and concentration) generated by Laser Ablation is of great interest due to its impact on the analytical performances when coupled to Inductively Coupled Plasma Mass Spectrometry (ICPMS). The capabilities of High Resolution ICPMS as a direct tool to characterize nanoparticles produced by femtosecond Laser Ablation of pure copper are presented. ...
DOI:: 10.1021/acs.analchem.7b01041
: https://doi.org/10.1021/acs.analchem.7b01041

82. Direct Sampling and Analysis of Atmospheric Particulate Organic Matter by Proton-Transfer-Reaction Mass Spectrometry

Author:: Müller Markus; Eichler Philipp; D’Anna Barbara; Tan Wen; Wisthaler Armin
Source:: Analytical chemistry 2017 v.89 no.20 pp. 10889-10897
ISSN:: 1520-6882
Subject:: qualitative analysis; traffic; autumn; polycyclic aromatic hydrocarbons; ionization; nicotine; spectrometers; volatilization; chemical analysis; aerosols; particulate organic carbon; resin acids; burning; oxidation; cities; mass spectrometry; biomass; oleic acid
Abstract:: ... We report on a new method for analyzing atmospheric submicrometer particulate organic matter which combines direct particle sampling and volatilization with online chemical ionization mass spectrometric analysis. Technically, the method relies on the combined use of a CHARON (“Chemical Analysis of Aerosol Online”) particle inlet and a proton-transfer-reaction time-of-flight mass spectrometer (PTR- ...
DOI:: 10.1021/acs.analchem.7b02582
: https://doi.org/10.1021/acs.analchem.7b02582

83. Droplet Assisted Inlet Ionization for Online Analysis of Airborne Nanoparticles

Author:: Horan Andrew J.; Apsokardu Michael J.; Johnston Murray V.
Source:: Analytical chemistry 2017 v.89 no.2 pp. 1059-1062
ISSN:: 1520-6882
Subject:: aerosols; angiotensin II; bovine serum albumin; breathing; chemical composition; climate; droplets; drugs; human health; ionization; ions; nanoparticles; polypropylenes; spectrometers; temperature; thermometers; volatilization; working conditions
Abstract:: ... Airborne nanoparticles play a key role in climate effects as well as impacting human health. Their small mass and complex chemical composition represent significant challenges for analysis. This work introduces a new ionization method, droplet assisted inlet ionization (DAII), where aqueous droplets are produced from airborne nanoparticles. When these droplets enter the mass spectrometer through a ...
DOI:: 10.1021/acs.analchem.6b04718
: https://doi.org/10.1021/acs.analchem.6b04718

84. Enhanced Quality Factor Label-free Biosensing with Micro-Cantilevers Integrated into Microfluidic Systems

Author:: Kartanas Tadas; Ostanin Victor; Challa Pavan Kumar; Daly Ronan; Charmet Jerome; Knowles Tuomas P.J.
Source:: Analytical chemistry 2017 v.89 no.22 pp. 11929-11936
ISSN:: 1520-6882
Subject:: acoustics; aerosols; detection limit; droplets; inorganic salts; liquids; nozzles; proteins; solutes
Abstract:: ... Microelectromechanical systems (MEMS) have enabled the development of a new generation of sensor platforms. Acoustic sensor operation in liquid, the native environment of biomolecules, causes, however, significant degradation of sensing performance due to viscous drag and relies on the availability of capture molecules to bind analytes of interest to the sensor surface. Here, we describe a strateg ...
DOI:: 10.1021/acs.analchem.7b01174
: https://doi.org/10.1021/acs.analchem.7b01174

85. Expanding Single Particle Mass Spectrometer Analyses for the Identification of Microbe Signatures in Sea Spray Aerosol

Author:: Sultana Camille M.; Al-Mashat Hashim; Prather Kimberly A.
Source:: Analytical chemistry 2017 v.89 no.19 pp. 10162-10170
ISSN:: 1520-6882
Subject:: aerosols; climate; coatings; environmental factors; ice nucleation; microorganisms; seawater; sodium chloride; spectrometers; tracer techniques; weather
Abstract:: ... Ocean-derived microbes in sea spray aersosol (SSA) have the potential to influence climate and weather by acting as ice nucleating particles in clouds. Single particle mass spectrometers (SPMSs), which generate in situ single particle composition data, are excellent tools for characterizing aerosols under changing environmental conditions as they can provide high temporal resolution and require no ...
DOI:: 10.1021/acs.analchem.7b00933
: https://doi.org/10.1021/acs.analchem.7b00933

86. First Identification of Palytoxin-Like Molecules in the Atlantic Coral Species Palythoa canariensis

Author:: María Fraga; Natalia Vilariño; M. Carmen Louzao; Lucía Molina; Yanira López; Mark Poli; Luis M. Botana
Source:: Analytical chemistry 2017 v.89 no.14 pp. 7438-7446
ISSN:: 1520-6882
Subject:: Miozoa; Trichodesmium; adverse effects; aerosols; corals; freeze drying; immunoassays; liquid chromatography; seafoods; spectrometers; toxins; Atlantic Ocean
Abstract:: ... Palytoxin (PLTX) is a complex marine toxin produced by Zoanthids (Palyhtoa), dinoflagellates (Ostreopsis), and cyanobacteria (Trichodesmium). Contact with PLTX-like compounds present in aerosols or marine organisms has been associated with adverse effects on humans. The worldwide distribution of producer species and seafood contaminated with PLTX-like molecules illustrates the global threat to hum ...
DOI:: 10.1021/acs.analchem.7b01003
: https://doi.org/10.1021/acs.analchem.7b01003

87. High Time-Resolution Optical Sensor for Monitoring Atmospheric Nitrogen Dioxide

Author:: Yong Tian; Xiaomin Zhang; Huiyan Shen; Aifeng Liu; Zongshan Zhao; Ming-Li Chen; Xu-Wei Chen
Source:: Analytical chemistry 2017 v.89 no.24 pp. 13064-13068
ISSN:: 1520-6882
Subject:: aerosols; air; air quality; detection limit; light emitting diodes; monitoring; nitrogen dioxide; polypropylenes; pumps; statistical analysis; China
Abstract:: ... High time-resolution monitoring of nitrogen dioxide (NO₂) is of great importance for studying the formation mechanism of aerosols and improving air quality. Based on the Griess–Saltzman (GS) reaction, a portable NO₂ optical sensor was developed by employing a porous polypropylene membrane tube (PPMT) integrated gas permeation collector and detector. The PPMT was filled with GS reagents and covered ...
DOI:: 10.1021/acs.analchem.7b03578
: https://doi.org/10.1021/acs.analchem.7b03578

88. Liquid Spray Dielectric Barrier Discharge Induced Plasma–Chemical Vapor Generation for the Determination of Lead by ICPMS

Author:: Liu Xing; Zhu Zhenli; Li Huilai; He Dong; Li Yatai; Zheng Hongtao; Gan Yiqun; Li Yanxiang; Belshaw Nicholas Stanley; Hu Shenghong
Source:: Analytical chemistry 2017 v.89 no.12 pp. 6827-6833
ISSN:: 1520-6882
Subject:: basalt; lead; aerosols; soil; streams; formic acid; hydrochloric acid; statistical analysis; atomic absorption spectrometry; metal ions; vapors
Abstract:: ... In the present study, a novel and sensitive liquid spray dielectric barrier discharge induced plasma–chemical vapor generation technique (LSDBD–CVG) is developed for the determination of lead concentration by inductively coupled plasma mass spectrometry (ICPMS). The dissolved Pb²⁺ is readily converted to volatile species by LSDBD plasma induced chemical processes in the presence of 5% (v/v) formic ...
DOI:: 10.1021/acs.analchem.7b01255
: https://doi.org/10.1021/acs.analchem.7b01255

89. Mass Spectrometry Characterization of Peroxycarboxylic Acids as Proxies for Reactive Oxygen Species and Highly Oxygenated Molecules in Atmospheric Aerosols

Author:: Steimer Sarah S.; Kourtchev Ivan; Kalberer Markus
Source:: Analytical chemistry 2017 v.89 no.5 pp. 2873-2879
ISSN:: 1520-6882
Subject:: aerosols; carbon; carboxylic acids; ionization; liquid chromatography; mass spectrometry; reactive oxygen species; spectrometers; toxicity
Abstract:: ... A significant fraction of atmospheric aerosol particles is composed of organic material with a highly complex but poorly characterized composition. For a better understanding of aerosol effects and processes in the atmosphere, a more detailed knowledge of aerosol components at a molecular level is needed. Peroxy acids might play a significant role in particle toxicity, due to their oxidizing prope ...
DOI:: 10.1021/acs.analchem.6b04127
: https://doi.org/10.1021/acs.analchem.6b04127

90. Quantifying Surface Area of Nanosheet Graphene Oxide Colloid Using a Gas-Phase Electrostatic Approach

Author:: Chang Wei-Chang; Cheng Shiuh-Cherng; Chiang Wei-Hung; Liao Jia-Liang; Ho Rong-Ming; Hsiao Ta-Chih; Tsai De-Hao
Source:: Analytical chemistry 2017 v.89 no.22 pp. 12217-12222
ISSN:: 1520-6882
Subject:: aerosols; colloids; drying; gases; graphene oxide; image analysis; nanosheets; surface area
Abstract:: ... We demonstrate a new, facile gas-phase electrostatic approach to successfully quantify equivalent surface area of graphene oxide (GO) colloid on a number basis. Mobility diameter (dₚ,ₘ)-based distribution and the corresponding equivalent surface area (SA) of GO colloids (i.e., with different lateral aspect ratios) were able to be identified by electrospray-differential mobility analysis (ES-DMA) c ...
DOI:: 10.1021/acs.analchem.7b02969
: https://doi.org/10.1021/acs.analchem.7b02969

91. Raman Spectroscopy of Single Light-Absorbing Carbonaceous Particles Levitated in Air Using an Annular Laser Beam

Author:: Uraoka Masaru; Maegawa Keisuke; Ishizaka Shoji
Source:: Analytical chemistry 2017 v.89 no.23 pp. 12866-12871
ISSN:: 1520-6882
Subject:: Raman spectroscopy; acetylene; aerosols; air; chemical composition; glass; heat; hydroxyl radicals; oils; oxidation; ozone; physicochemical properties; soot
Abstract:: ... A laser trapping technique is a powerful means to investigate the physical and chemical properties of single aerosol particles in a noncontact manner. However, optical trapping of strongly light-absorbing particles such as black carbon or soot is quite difficult because the repulsive force caused by heat is orders of magnitude larger than the attractive force of radiation pressure. In this study, ...
DOI:: 10.1021/acs.analchem.7b03455
: https://doi.org/10.1021/acs.analchem.7b03455

92. Rapid Elemental Analysis of Aerosols Using Atmospheric Glow Discharge Optical Emission Spectroscopy

Author:: Zheng Lina; Kulkarni Pramod
Source:: Analytical chemistry 2017 v.89 no.12 pp. 6551-6558
ISSN:: 1520-6882
Subject:: aerosols; atomization; cadmium; cathodes; detection limit; emissions; manganese; particulates; radio waves; sodium; spectrometers; spectroscopy; sucrose; temperature
Abstract:: ... A new, low-cost approach based on the application of atmospheric radio frequency glow discharge (rf-GD) optical emission spectroscopy (OES) has been developed for near real-time measurement of multielemental concentration in airborne particulate phase. This method involves deposition of aerosol particles on the tip of a cathode in a coaxial microelectrode system, followed by ablation, atomization, ...
DOI:: 10.1021/acs.analchem.7b00691
PubMed:: 28513144
PubMed Central:: PMC5555147
: https://doi.org/10.1021/acs.analchem.7b00691

93. Signal Transductions of BEAS-2B Cells in Response to Carcinogenic PM2.5 Exposure Based on a Microfluidic System

Author:: Zheng Lulu; Liu Sixiu; Zhuang Guoshun; Xu Jian; Liu Qi; Zhang Xinlian; Deng Congrui; Guo Zhigang; Zhao Wang; Liu Tingna; Wang Yiqi; Zhang Yuxiao; Lin Jing; Wang Qiongzhen; Sui Guodong
Source:: Analytical chemistry 2017 v.89 no.10 pp. 5413-5421
ISSN:: 1520-6882
Subject:: aerosols; air; angiogenesis; apoptosis; arsenic; calcium; carcinogens; cell proliferation; chemical composition; disease course; endocytosis; gene expression; mitochondria; mitochondrial membrane; mitogen-activated protein kinase; neoplasms; particulates; polycyclic aromatic hydrocarbons; reactive oxygen species; risk reduction; sequence analysis; signal transduction; traffic; transcriptomics; transmission electron microscopy; vascular endothelial growth factors; zinc; China
Abstract:: ... PM₂.₅ (particulate matter less than 2.5 μm in diameter) is considered as a harmful carcinogen. Determining the precise relationship between the chemical constituents of PM₂.₅ in the air and cancer progression could aid the treatment of environment related disease and establishing risk reduction strategies. Herein, we used transcriptomics (RNA-seq) and an integrated microfluidic system to identify ...
DOI:: 10.1021/acs.analchem.7b00218
: https://doi.org/10.1021/acs.analchem.7b00218

94. Solid, Semisolid, and Liquid Phase States of Individual Submicrometer Particles Directly Probed Using Atomic Force Microscopy

Author:: Lee Hansol D.; Ray Kamal K.; Tivanski Alexei V.
Source:: Analytical chemistry 2017 v.89 no.23 pp. 12720-12726
ISSN:: 1520-6882
Subject:: aerosols; ambient temperature; atomic force microscopy; climate; liquids; modulus of elasticity; relative humidity; sucrose; surface tension; viscoelasticity; viscosity
Abstract:: ... Currently, the impact of various phase states of aerosols on the climate is not well understood, especially for submicrometer sized aerosol particles that typically have extended lifetime in the atmosphere. This is largely due to the inherent size limitations present in current experimental techniques that aim to directly assess the phase states of fine aerosol particles. Herein we present a techn ...
DOI:: 10.1021/acs.analchem.7b02755
: https://doi.org/10.1021/acs.analchem.7b02755

95. Use of Calculated Physicochemical Properties to Enhance Quantitative Response When Using Charged Aerosol Detection

Author:: Robinson Max W.; Hill Alan P.; Readshaw Simon A.; Hollerton John C.; Upton Richard J.; Lynn Sean M.; Besley Steve C.; Boughtflower Bob J.
Source:: Analytical chemistry 2017 v.89 no.3 pp. 1772-1777
ISSN:: 1520-6882
Subject:: aerosols; high performance liquid chromatography; nuclear magnetic resonance spectroscopy; physicochemical properties; reference standards; surface area
Abstract:: ... Universal quantitative detection without the need for analyte reference standards would offer substantial benefits in many areas of analytical science. The quantitative capability of high-performance liquid chromatography (HPLC) with charged aerosol detection (CAD) was investigated for 50 compounds with a wide range of physical and chemical properties. It is widely believed that CAD is a mass dete ...
DOI:: 10.1021/acs.analchem.6b04060
: https://doi.org/10.1021/acs.analchem.6b04060

96. 1064 nm Dispersive Raman Microspectroscopy and Optical Trapping of Pharmaceutical Aerosols

Author:: Peter J. Gallimore; Nick M. Davidson; Markus Kalberer; Francis D. Pope; Andrew D. Ward
Source:: Analytical chemistry 2018 v.90 no.15 pp. 8838-8844
ISSN:: 1520-6882
Subject:: Raman spectroscopy; aerosols; asthma; chemical analysis; chemical composition; fluorescence; irradiation; lasers; latex; light microscopy; microparticles; polystyrenes; sulfates; thermodynamics; wavelengths
Abstract:: ... Raman spectroscopy is a powerful tool for investigating chemical composition. Coupling Raman spectroscopy with optical microscopy (Raman microspectroscopy) and optical trapping (Raman tweezers) allows microscopic length scales and, hence, femtolitre volumes to be probed. Raman microspectroscopy typically uses UV/visible excitation lasers, but many samples, including organic molecules and complex t ...
DOI:: 10.1021/acs.analchem.8b00817
: https://doi.org/10.1021/acs.analchem.8b00817

97. Accurate Quantification of Radiosulfur in Chemically Complex Atmospheric Samples

Author:: Mang Lin; Mark H. Thiemens
Source:: Analytical chemistry 2018 v.90 no.4 pp. 2884-2890
ISSN:: 1520-6882
Subject:: aerosols; chemical composition; color; half life; hydrology; laboratory experimentation; models; radionuclides; sulfur
Abstract:: ... An ultralow-level liquid scintillation counting (LSC) technique has been used in measuring radiosulfur (cosmogenic ³⁵S) in natural samples. The ideal half-life of ³⁵S (∼87 days) renders it a new way to examine various biogeochemical problems. A major limitation of the technique is that complex chemical compositions in atmospheric samples may lead to color quenching of LSC cocktails, a serious prob ...
DOI:: 10.1021/acs.analchem.7b05079
: https://doi.org/10.1021/acs.analchem.7b05079

98. Analysis of Crystalline Silica Aerosol Using Portable Raman Spectrometry: Feasibility of Near Real-Time Measurement

Author:: Lina Zheng; Pramod Kulkarni; M. Eileen Birch; Kevin Ashley; Shijun Wei
Source:: Analytical chemistry 2018 v.90 no.10 pp. 6229-6239
ISSN:: 1520-6882
Subject:: Raman spectroscopy; X-ray diffraction; aerosols; air; ashing; calibration; filters; infrared spectroscopy; silica; working conditions
Abstract:: ... A Raman spectroscopy based method has been developed for measurement of trace airborne concentrations of respirable crystalline silica (RCS) using various aerosol sampling and analysis techniques. Three aerosol microconcentration techniques were investigated for effective coupling of collected particulate samples with micro-Raman spectroscopy: (i) direct analysis on a particulate filter after focu ...
DOI:: 10.1021/acs.analchem.8b00830
: https://doi.org/10.1021/acs.analchem.8b00830

99. Comprehensive Molecular Characterization of Atmospheric Brown Carbon by High Resolution Mass Spectrometry with Electrospray and Atmospheric Pressure Photoionization

Author:: Peng Lin; Lauren T. Fleming; Sergey A. Nizkorodov; Julia Laskin; Alexander Laskin
Source:: Analytical chemistry 2018 v.90 no.21 pp. 12493-12502
ISSN:: 1520-6882
Subject:: absorption; aerosols; aromatic acids; atmospheric pressure; biofuels; biomass; burning; carbon; chemical composition; environmental impact; high performance liquid chromatography; human health; ionization; mass spectrometry; nitroaromatic compounds; phenols; polar compounds; polycyclic aromatic hydrocarbons; sage; solar radiation; toxins; water solubility
Abstract:: ... Light-absorbing components of atmospheric organic aerosols, which are collectively termed “brown carbon” (BrC), are ubiquitous in the atmosphere. They affect absorption of solar radiation by aerosols in the atmosphere and human health as some of them have been identified as potential toxins. Understanding the sources, formation, atmospheric evolution, and environmental effects of BrC requires mole ...
DOI:: 10.1021/acs.analchem.8b02177
: https://doi.org/10.1021/acs.analchem.8b02177

100. Development and Characterization of a Laser-Induced Acoustic Desorption Source

Author:: Zhipeng Huang; Tim Ossenbrüggen; Igor Rubinsky; Matthias Schust; Daniel A. Horke; Jochen Küpper
Source:: Analytical chemistry 2018 v.90 no.6 pp. 3920-3927
ISSN:: 1520-6882
Subject:: acoustics; aerosols; desorption; ionization; lasers; spraying; temperature
Abstract:: ... A laser-induced acoustic desorption source, developed for use at central facilities, such as free-electron lasers, is presented. It features prolonged measurement times and a fixed interaction point. A novel sample deposition method using aerosol spraying provides a uniform sample coverage and hence stable signal intensity. Utilizing strong-field ionization as a universal detection scheme, the pro ...
DOI:: 10.1021/acs.analchem.7b04797
: https://doi.org/10.1021/acs.analchem.7b04797

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1. A Wide Spectral Range Photoacoustic Aerosol Absorption Spectrometer

2. Application of Time-of-Flight Aerosol Mass Spectrometry for the Online Measurement of Gaseous Molecular Iodine

3. Chemical Analysis of Complex Organic Mixtures Using Reactive Nanospray Desorption Electrospray Ionization Mass Spectrometry

4. Chemical Composition of Ambient Nanoparticles on a Particle-by-Particle Basis

5. Diode Laser Thermal Vaporization Inductively Coupled Plasma Mass Spectrometry

6. Direct Surface Analysis of Time-Resolved Aerosol Impactor Samples with Ultrahigh-Resolution Mass Spectrometry

7. Identification of Weak and Strong Organic Acids in Atmospheric Aerosols by Capillary Electrophoresis/Mass Spectrometry and Ultra-High-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

8. Investigation of the Chemical Mixing State of Individual Asian Dust Particles by the Combined Use of Electron Probe X-ray Microanalysis and Raman Microspectrometry

9. Investigation of the Utility of Laser-Secondary Neutral Mass Spectrometry for the Detection of Polyaromatic Hydrocarbons in Individual Atmospheric Aerosol Particles

10. Microfluidic Paper-Based Analytical Device for Particulate Metals

11. Online Characterization of Particles and Gases with an Ambient Electrospray Ionization Source

12. Optical Properties of Dispersed Aerosols in the Near Ultraviolet (355 nm): Measurement Approach and Initial Data

13. Quantitative Analysis of Liquids from Aerosols and Microdrops Using Laser Induced Breakdown Spectroscopy

14. Real-Time Shape-Based Particle Separation and Detailed in Situ Particle Shape Characterization

15. The Necessity of Microscopy to Characterize the Optical Properties of Size-Selected, Nonspherical Aerosol Particles

16. Analytical Methodology for Determination of Organic Aerosol Functional Group Distributions

17. Calculating the Net Activity Uncertainty if the Background Includes a Nonstationary Component

18. Direct Measurements of Mass-Specific Optical Cross Sections of Single-Component Aerosol Mixtures

19. Fast Chemical Imaging at High Spatial Resolution by Laser Ablation Inductively Coupled Plasma Mass Spectrometry

20. Formation of a Stable Mimic of Ambient Particulate Matter Containing Viable Infectious Respiratory Syncytial Virus and Its Dry-Deposition Directly onto Cell Cultures

21. Halo-Shaped Flowing Atmospheric Pressure Afterglow: A Heavenly Design for Simplified Sample Introduction and Improved Ionization in Ambient Mass Spectrometry

22. Hydrogen Peroxide Detection in Wet Air with a Prussian Blue Based Solid Salt Bridged Three Electrode System

23. Ion Mobility-Mass Spectrometry with a Radial Opposed Migration Ion and Aerosol Classifier (ROMIAC)

24. Iron Isotope Composition of Particles Produced by UV-Femtosecond Laser Ablation of Natural Oxides, Sulfides, and Carbonates

25. Light Scattering and Extinction Measurements Combined with Laser-Induced Incandescence for the Real-Time Determination of Soot Mass Absorption Cross Section

26. Low-Temperature Microchip Nonaqueous Capillary Electrophoresis of Aliphatic Primary Amines: Applications to Titan Chemistry

27. Rapid Quantification of Yeast Lipid using Microwave-Assisted Total Lipid Extraction and HPLC-CAD

28. Real Time in Situ Chemical Characterization of Submicrometer Organic Particles Using Direct Analysis in Real Time-Mass Spectrometry

29. Sampler for Collection and Analysis of Low Vapor Pressure Chemical (LVPC) Particulates/Aerosols

30. Simultaneous Analysis of the Equilibrium Hygroscopicity and Water Transport Kinetics of Liquid Aerosol

31. Standard Addition Method for Laser Ablation ICPMS Using a Spinning Platform

32. Sub 2-μm Macroporous Silica Particles Derivatized for Enhanced Lectin Affinity Enrichment of Glycoproteins

33. Wavelength-Resolved Optical Extinction Measurements of Aerosols Using Broad-Band Cavity-Enhanced Absorption Spectroscopy over the Spectral Range of 445–480 nm

34. A UV–Vis Photoacoustic Spectrophotometer

35. Characterization and Stability Study of Polysorbate 20 in Therapeutic Monoclonal Antibody Formulation by Multidimensional Ultrahigh-Performance Liquid Chromatography–Charged Aerosol Detection–Mass Spectrometry

36. Cryo-Transmission Electron Microscopy Imaging of the Morphology of Submicrometer Aerosol Containing Organic Acids and Ammonium Sulfate

37. Detection of Uranium and Chemical State Analysis of Individual Radioactive Microparticles Emitted from the Fukushima Nuclear Accident Using Multiple Synchrotron Radiation X-ray Analyses

38. Development of an Organic Lateral Resolution Test Device for Imaging Mass Spectrometry

39. Evaluation of Different Synchrotron Beamline Configurations for X-ray Fluorescence Analysis of Environmental Samples

40. Improving the Quantification of Secondary Organic Aerosol Using a Microflow Reactor Coupled to HPLC-MS and NMR to Manufacture Ad Hoc Calibration Standards

41. Influence of Collecting Substrates on the Characterization of Hygroscopic Properties of Inorganic Aerosol Particles

42. Measurement of Sub-2 nm Clusters of Pristine and Composite Metal Oxides during Nanomaterial Synthesis in Flame Aerosol Reactors

43. Mechanism and Sensitivity of Anion Detection Using Rationally Designed Unsymmetrical Dications in Paired Ion Electrospray Ionization Mass Spectrometry

44. Method for Characterization of Low Molecular Weight Organic Acids in Atmospheric Aerosols Using Ion Chromatography Mass Spectrometry

45. Total Reflection X-ray Fluorescence Analysis of Airborne Silver Nanoparticles from Fabrics

46. Aerosol Analysis via Electrostatic Precipitation-Electrospray Ionization Mass Spectrometry

47. Determination of the Sulfur Isotope Ratio in Carbonyl Sulfide Using Gas Chromatography/Isotope Ratio Mass Spectrometry on Fragment Ions 32S+, 33S+, and 34S+

48. Elemental Analysis of Complex Organic Aerosol Using Isotopic Labeling and Unit-Resolution Mass Spectrometry

49. Fluorescent Sulfur-Tagged Europium(III) Coordination Polymers for Monitoring Reactive Oxygen Species

50. High-Speed, High-Resolution, Multielemental Laser Ablation-Inductively Coupled Plasma-Time-of-Flight Mass Spectrometry Imaging: Part I. Instrumentation and Two-Dimensional Imaging of Geological Samples

51. High-Speed, Integrated Ablation Cell and Dual Concentric Injector Plasma Torch for Laser Ablation-Inductively Coupled Plasma Mass Spectrometry

52. Investigation of a Combined Microdroplet Generator and Pneumatic Nebulization System for Quantitative Determination of Metal-Containing Nanoparticles Using ICPMS

53. Low-Temperature Plasma Ionization-Mass Spectrometry for the Analysis of Compounds in Organic Aerosol Particles

54. Mass Spectrometric Sampling of a Liquid Surface by Nanoliter Droplet Generation from Bursting Bubbles and Focused Acoustic Pulses: Application to Studies of Interfacial Chemistry

55. Measurement of Gas and Aerosol Phase Absorption Spectra across the Visible and Near-IR Using Supercontinuum Photoacoustic Spectroscopy

56. Miniature Flow-Through Low-Temperature Plasma Ionization Source for Ambient Ionization of Gases and Aerosols

57. Online Analysis of Single Cyanobacteria and Algae Cells under Nitrogen-Limited Conditions Using Aerosol Time-of-Flight Mass Spectrometry

58. Radial Diffusion and Penetration of Gas Molecules and Aerosol Particles through Laminar Flow Reactors, Denuders, and Sampling Tubes

59. Single-Particle Time-of-Flight Mass Spectrometry Utilizing a Femtosecond Desorption and Ionization Laser

60. Speciation Analysis of 129I and 127I in Aerosols Using Sequential Extraction and Mass Spectrometry Detection

61. Surface Enhanced Raman Spectroscopy Enables Observations of Previously Undetectable Secondary Organic Aerosol Components at the Individual Particle Level

62. “Wave” Signal-Smoothing and Mercury-Removing Device for Laser Ablation Quadrupole and Multiple Collector ICPMS Analysis: Application to Lead Isotope Analysis

63. Abundance and Impact of Doubly Charged Polyatomic Argon Interferences in ICPMS Spectra

64. Characterization of Highly Oxidized Molecules in Fresh and Aged Biogenic Secondary Organic Aerosol

65. Compositional Analysis of Aerosols Using Calibration-Free Laser-Induced Breakdown Spectroscopy

66. Liquid Nebulization–Ion Mobility Spectrometry Based Quantification of Nanoparticle–Protein Conjugate Formation

67. Novel Image Metrics for Retrieval of the Lateral Resolution in Line Scan-Based 2D LA-ICPMS Imaging via an Experimental-Modeling Approach

68. Preconcentration and Atomization of Arsane in a Dielectric Barrier Discharge with Detection by Atomic Absorption Spectrometry

69. Quantifying the Hygroscopic Growth of Individual Submicrometer Particles with Atomic Force Microscopy

70. Raman Spectroscopy of Isotopic Water Diffusion in Ultraviscous, Glassy, and Gel States in Aerosol by Use of Optical Tweezers