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- Zhao, Yonghui, et al. Show all 15 Authors
- Analytical chemistry 2019 v.92 no.1 pp. 1346-1354
- DNA; DNA methylation; bisulfites; genes; hydrophobicity; proteins; proteomics; ribosomal RNA; sequence analysis
- ... 5-Methylcytosine is found in both DNA and RNA; although its functions in DNA are well established, the exact role of 5-methylcytidine (m⁵C) in RNA remains poorly defined. Here we identified, by employing a quantitative proteomics method, multiple candidate recognition proteins of m⁵C in RNA, including several YTH domain-containing family (YTHDF) proteins. We showed that YTHDF2 could bind directly ...
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