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- Zhang, Yuwei, et al. Show all 7 Authors
- Analytical chemistry 2019 v.91 no.3 pp. 1936-1943
- biosensors; blood serum; cAMP-dependent protein kinase; cyclic AMP; disease diagnosis; drugs; electrochemistry; electrodes; enzyme activity; gold; models; peptides; phosphorylation; polymerization; polymers; proteins; screening
- ... Phosphorylation of proteins catalyzed by protein kinases (PKs) is essential to many biological processes; the sensitive detection of PK activity and the screening of PK inhibitors are thus integral to disease diagnosis and drug discovery. Herein, a highly sensitive biosensor has been fabricated for the electrochemical detection of PK activity by exploiting the electrochemically controlled reversib ...