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- Scrivens, James H., et al. Show all 6 Authors
- Analytical chemistry 2014 v.86 no.21 pp. 10789-10795
- proteins; ions; glycosylation; data collection; high performance liquid chromatography; spectroscopy; dextran; databases; stereoisomers
- ... Glycosylation is one of the most common post-translational modifications occurring in proteins. A detailed structural characterization of the involved carbohydrates, however, is still one of the greatest challenges in modern glycoproteomics, since multiple regio- and stereoisomers with an identical monosaccharide composition may exist. Recently, ion mobility-mass spectrometry (IM-MS), a technique ...
- Scrivens, James H., et al. Show all 3 Authors
- Analytical chemistry 2012 v.84 no.15 pp. 6521-6529
- atmospheric pressure; carbon; chemical structure; esters; ethylene oxide; ingredients; mass spectrometry; molecular weight; polysorbates; screening
- ... Complex synthetic formulations based on polysorbates can be challenging to characterize. They may be composed of many similar products including those of the same molecular weight, which cannot be readily separated by separation science approaches. Carbon number variation and ethylene oxide distribution add to the complexity. The properties of these formulations will be dependent on the chemical s ...