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You searched for: Subject "microfluidic technology" Remove constraint Subject: "microfluidic technology" Journal Analytical methods Remove constraint Journal: Analytical methods Publication Year 2018 Remove constraint Publication Year: 2018
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1. Microfluidics in coagulation monitoring devices: a mini review

Author:
Harris, Leanne F.; Killard, Anthony J.
Source:
Analytical methods 2018 v.10 no.30 pp. 3714-3719
ISSN:
1759-9679
Subject:
microfluidic technology,   etc   ; analytical methods; coagulation; decision making; hemorrhage; hemostasis; monitoring; mortality; patient care;     Show all 9 Subjects
Abstract:
... Diagnosis and monitoring of disorders of coagulation and disturbances in haemostasis has been around for many years. Thrombotic and bleeding disorders are amongst the leading causes of mortality in the developed world, thus driving research in this area. The simplicity with which miniaturised devices operate and their application to the study of coagulation and haemostasis offer potential advantag ...
DOI:
10.1039/c8ay01230j

2. A review of centrifugal microfluidics in environmental monitoring

Author:
Maguire, I.; O'Kennedy, R.; Ducrée, J.; Regan, F.
Source:
Analytical methods 2018 v.10 no.13 pp. 1497-1515
ISSN:
1759-9679
Subject:
microfluidic technology,   etc   ; analytical methods; automation; cost effectiveness; electrochemistry; environmental monitoring; manufacturing; mixing;     Show all 8 Subjects
Abstract:
... There is currently a gap in the use of centrifugal microfluidics in the field of environmental sensing. This review provides theoretical perspectives that have been demonstrated for applications in other domains and recommends adaptations for environmental sensing. Current approaches of centrifugal systems reported are primarily in the area of biosensing and electrochemical detection. In the case ...
DOI:
10.1039/c8ay00361k

3. Use of 3D printing and modular microfluidics to integrate cell culture, injections and electrochemical analysis

Author:
Munshi, Akash S.; Chen, Chengpeng; Townsend, Alexandra D.; Martin, R. Scott
Source:
Analytical methods 2018 v.10 no.27 pp. 3364-3374
ISSN:
1759-9679
Subject:
microfluidic technology,   etc   ; adenosine triphosphate; analytical methods; cell culture; electrochemistry; electrodes; endothelial cells; gold; half life; nitric oxide; polystyrenes; vasodilation;     Show all 12 Subjects
Abstract:
... Fabrication of microchip-based devices using 3D printing technology offers a unique platform to create separate modules that can be put together when desired for analysis. A 3D printed module approach offers various advantages such as file sharing and the ability to easily replace, customize, and modify the individual modules. Here, we describe the use of a modular approach to electrochemically de ...
DOI:
10.1039/c8ay00829a

4. Label-free mesenchymal stem cell enrichment from bone marrow samples by inertial microfluidics

Author:
Lee, Lap Man; Rosano, Jenna M.; Wang, Yi; Klarmann, George J.; Garson, Charles J.; Prabhakarpandian, Balabhaskar; Pant, Kapil; Alvarez, Luis M.; Lai, Eva
Source:
Analytical methods 2018 v.10 no.7 pp. 713-721
ISSN:
1759-9679
Subject:
microfluidic technology,   etc   ; analytical methods; bone marrow; bone marrow cells; cartilage; mesenchymal stromal cells; mice; orthopedics; stem cells; therapeutics; viability;     Show all 11 Subjects
Abstract:
... Isolation of pure populations of mesenchymal stem cells from bone marrow aspirate is a critical need in regenerative medicine such as orthopedic and cartilage reconstruction with important clinical and therapeutic implications. Currently available stem cell isolation systems mainly rely on intrusive immuno-labeling techniques. Mesenchymal stem cells in bone marrow samples are typically larger than ...
DOI:
10.1039/c7ay02500a

5. Droplet microfluidics in thermoplastics: device fabrication, droplet generation, and content manipulation using integrated electric and magnetic fields

Author:
Sahore, Vishal; Doonan, Steven R.; Bailey, Ryan C.
Source:
Analytical methods 2018 v.10 no.35 pp. 4264-4274
ISSN:
1759-9679
Subject:
microfluidic technology,   etc   ; beta-galactosidase; chemical analysis; droplets; enzyme substrates; geometry; hydrophobicity; magnetic fields; olefin; polymethylmethacrylate; potassium channels; silicon; thermoplastics; washing; wastes;     Show all 15 Subjects
Abstract:
... We have developed droplet microfluidic devices in thermoplastics and demonstrated the integration of key functional components that not only facilitate droplet generation, but also include electric field-assisted reagent injection, droplet splitting, and magnetic field-assisted bead extraction. We manufactured devices in poly(methyl methacrylate) and cyclic olefin polymer using a hot-embossing pro ...
DOI:
10.1039/c8ay01474d

6. Automated 4-sample protein immunoassays using 3D-printed microfluidics

Author:
Kadimisetty, Karteek; Spak, Andrew P.; Bhalerao, Ketki S.; Sharafeldin, Mohamed; Mosa, Islam M.; Lee, Norman H.; Rusling, James F.
Source:
Analytical methods 2018 v.10 no.32 pp. 4000-4006
ISSN:
1759-9679
Subject:
microfluidic technology,   etc   ; Internet; analytical methods; automation; blood serum; carbon nanotubes; detection limit; diagnostic techniques; enzyme-linked immunosorbent assay; graphene; liquids; nanoparticles; prostate-specific antigen; proteins; rapid methods;     Show all 15 Subjects
Abstract:
... Low cost, miniaturized assay platforms that work with small sample volumes, high sensitivity and rapid detection will have high value in future biomolecular diagnostics. Herein we report an automated, 3D printed electrochemiluminescent (ECL) immunoarray integrated with a nanostructured pyrolytic graphite sheet (PGS) microwell chip configured to detect 2 proteins simultaneously from complex liquid ...
DOI:
10.1039/c8ay01271g

7. Development of immunomagnetic droplet-based digital immuno-PCR for the quantification of prostate specific antigen

Author:
Zhou, Wenhan
Source:
Analytical methods 2018 v.10 no.29 pp. 3690-3695
ISSN:
1759-9679
Subject:
microfluidic technology,   etc   ; DNA; analytical methods; antigen-antibody reactions; antigens; blood serum; droplets; humans; immunoassays; magnetic fields; models; polymerase chain reaction; prostate-specific antigen; proteins; washing;     Show all 15 Subjects
Abstract:
... Immuno-PCR (IPCR) is an immunoassay that employs DNA as the signal generator and utilizes both the versatility of antigen–antibody interactions and the exponential amplification power of PCR. Droplet-based digital PCR (ddPCR) is the third and latest generation of PCR technology, and the integration of ddPCR into IPCR will hopefully enable the absolute quantification and highly sensitive detection ...
DOI:
10.1039/c8ay00921j