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1. Analysis of natural and synthetic folates in pharmaceuticals and foods: a review

Author:
Yin, Shuo; Yang, Yi; Li, Yongxin; Sun, Chengjun
Source:
Analytical methods 2017 v.10 no.1 pp. 9-21
ISSN:
1759-9679
Subject:
amino acid metabolism; analytical methods; cell division; children; developing countries; drugs; folic acid; food fortification; foods; pregnant women; quality control; vitamin B deficiency
Abstract:
... Folate (vitamin B₉) plays an important role in cell division and tissue growth by participating in the amino acid metabolism and nucleotide metabolism. Folate deficiency among pregnant women and children is common around the world, particularly in developing countries. Accurate folate analysis is critical for quality control in pharmaceutical and food products. This review briefly introduces the p ...
DOI:
10.1039/c7ay02501g

2. An ultrasensitive electrochemiluminescent d-alanine biosensor based on the synergetic catalysis of a hemin-functionalized composite and gold–platinum nanowires

Author:
Lin, Xia; Zhu, Shu; Xia, Qiao; Ma, Jiao; Fu, Yingzi
Source:
Analytical methods 2017 v.10 no.1 pp. 84-90
ISSN:
1759-9679
Subject:
D-amino-acid oxidase; amino acids; analytical methods; biosensors; catalytic activity; electron transfer; graphene; hydrogen peroxide; nanocarriers; nanowires
Abstract:
... Herein, an ultrasensitive and stereo-selective electrochemiluminescent (ECL) biosensor based on ECL signal amplification of luminol by the synergetic catalysis of a hemin-functionalized composite and gold–platinum nanowires (Au-PtNWs) has been designed for the detection of d-alanine (d-Ala). In the sensor design, d-amino acid oxidase (DAAO) was used to generate the ECL co-reactant (H₂O₂) for lumin ...
DOI:
10.1039/c7ay02483e

3. Determination of methylmercury in sediment and cyanobacteria samples: method validation and application to methylation investigation

Author:
Mendes, Louise Aparecida; Franco, Maione Wittig; Rodrigues Barbosa, Francisco Antônio; Aires de Carvalho, Paula Iannarelli; Carvalho de Lena, Jorge; Windmöller, Cláudia Carvalhinho
Source:
Analytical methods 2017 v.10 no.1 pp. 91-100
ISSN:
1759-9679
Subject:
Cyanobacteria; Stichococcus; analytical methods; biogeochemical cycles; biotransformation; derivatization; desorption; gold; mercury; methylation; methylmercury compounds; microalgae; mining; plankton; pyrolysis; reference standards; sediments; Brazil
Abstract:
... The aim of this work was to validate two methods for methylmercury (CH₃Hg⁺) determination in sediments and cyanobacteria and their application to the Hg methylation study of planktonic organisms in water from a contaminated site in Brazil. Analytical methods for the determination of CH₃Hg⁺ include many steps, and the necessity of adaptation to different matrices is very common and not always easy. ...
DOI:
10.1039/c7ay02415k

4. Plasmonic nanograting enhanced fluorescence for protein microarray analysis of carcinoembryonic antigen (CEA)

Author:
Liu, Chang; Meng, Fanling; Wang, Baogang; Zhang, Lei; Cui, Xiaoqiang
Source:
Analytical methods 2017 v.10 no.1 pp. 145-150
ISSN:
1759-9679
Subject:
analytical methods; antigens; biomarkers; detection limit; diagnostic techniques; fluorescence; glass; gold; nanogold; neoplasms; protein microarrays; proteomics
Abstract:
... The low sensitivity of protein microarrays has limited the wide application in diagnostics and high-throughput proteomic analysis. We present, for the first time, the exploration of protein microarray analysis on nanostructured plasmonic gold nanograting that showed a 10-fold fluorescence enhancement. The as-fabricated plasmonic protein microarray showed a limit of detection (LOD) of 0.36 ng mL⁻¹ ...
DOI:
10.1039/c7ay02232h

5. Validation of a lateral flow immunoassay for the rapid determination of aflatoxins in maize by solvent free extraction

Author:
Lattanzio, Veronica M. T.; Guarducci, Natascia; Powers, Stephen; Ciasca, Biancamaria; Pascale, Michelangelo; von Holst, Christoph
Source:
Analytical methods 2017 v.10 no.1 pp. 123-130
ISSN:
1759-9679
Subject:
aflatoxin B1; analytical methods; business enterprises; case studies; corn; food contamination; immunoassays; microbial contamination; normal values; regression analysis; screening; solvents; standard deviation
Abstract:
... The analytical performances of a lateral flow immunoassay (AFLA-V AQUA™, Vicam a Waters Business) for the determination of aflatoxins in maize were evaluated according to Commission Regulation (EU) No. 519/2014. This case study showed how a critical evaluation of validation results can provide a quite informative picture of kit performances for its use for different purposes. The validation study, ...
DOI:
10.1039/c7ay02249b

6. Ag@SiO₂ nanocube loaded miniaturized filter paper as a hybrid flexible plasmonic SERS substrate for trace melamine detection

Author:
Mekonnen, Menbere Leul; Su, Wei-Nien; Chen, Ching-Hsiang; Hwang, Bing-Joe
Source:
Analytical methods 2017 v.9 no.48 pp. 6823-6829
ISSN:
1759-9679
Subject:
analytical methods; anisotropy; detection limit; liquids; melamine; milk; nanosilver; paper; silica; silver
Abstract:
... A robust flexible paper-plasmonic hybrid SERS substrate is reported by exploiting the intrinsic properties of filter paper and anisotropic Ag@SiO₂ nanocubes. The fibrous structure of paper promotes the assemblage of sharp-edged nanostructures which significantly improved the SERS activity. An inexpensive sensing platform with reasonable distribution and interparticle spacing of nanocubes was obtai ...
DOI:
10.1039/c7ay02192e

7. A self-supported electrochemical sensor for simultaneous sensitive detection of trace heavy metal ions based on PtAu alloy/carbon nanofibers

Author:
Zhang, SongGe; Zhu, Han; Ma, PiMing; Duan, Fang; Dong, WeiFu; Du, MingLiang
Source:
Analytical methods 2017 v.9 no.48 pp. 6801-6807
ISSN:
1759-9679
Subject:
alloy nanoparticles; alloys; analytical methods; cadmium; carbon nanofibers; copper; electrochemistry; electrodes; heavy metals; lead; metal ions; sensors (equipment); surface area
Abstract:
... The key issue in efficient electrochemical detection of trace heavy metal ions (HMIs) is to design hierarchical nanostructure electrodes with high sensitivity and low detection limit. In this study, bimetallic PtAu alloy nanoparticles (PtAuNPs) with uniform size and distribution were constructed in electrospun carbon nanofibers (CNFs) by combining an electrospinning procedure and an in situ therma ...
DOI:
10.1039/c7ay02223a

8. Biosensor applications of graphene-nanocomposites bound oxidoreductive and hydrolytic enzymes

Author:
Husain, Qayyum
Source:
Analytical methods 2017 v.9 no.48 pp. 6734-6746
ISSN:
1759-9679
Subject:
acetylcholine; adsorption; analytical methods; biocatalysts; biosensors; caffeic acid; catechol; chlorpyrifos; clenbuterol; concanavalin A; electrodes; estradiol; ethanol; fuels; glucose; graphene; histamine; hydrogen peroxide; hydrogen sulfide; hydrolases; immobilized enzymes; nanocomposites; oxidoreductases; urea
Abstract:
... Graphene based nanocomposites have successfully been employed for high yield and stable immobilization of oxidoreductive and hydrolytic enzymes. Enzymes immobilized both via adsorption and covalent attachment on graphene nanocomposites were found highly stable against various types of denaturants and were noticed less sensitive to inhibition mediated by their specific inhibitors. The oxidoreductas ...
DOI:
10.1039/c7ay02606d

9. MicroRNA detection by an amplification-free biosensor based on controllable solid-state electrochemiluminescence quenched by charge transfer

Author:
Liu, Chang; Wang, Lin; Lu, Liping; Kang, Tianfang
Source:
Analytical methods 2017 v.9 no.48 pp. 6760-6768
ISSN:
1759-9679
Subject:
DNA; active sites; adsorption; analytical methods; biosensors; chemical bonding; detection limit; electrochemiluminescence; glassy carbon electrode; gold; microRNA; nanogold; neoplasms; thiols
Abstract:
... Effective and sensitive microRNA detection is a great challenge. Most microRNA assays use an amplification strategy to obtain high sensitivity, which makes them complicated. Herein, we present a simple and amplification-free solid-state electrochemiluminescence (ECL) biosensor for the detection of miRNA based on high effective quenching by ferrocene and using N-butyldiethanolamine (BDEA) as a more ...
DOI:
10.1039/c7ay01724c

10. Selective and low potential electrocatalytic oxidation and sensing of l-cysteine using metal impurity containing carbon black modified electrode

Author:
Sornambikai, Sundaram; Abdul Kadir, Mohammed Rafiq; Kumar, Annamalai Senthil; Ponpandian, Nagamony; Viswanathan, Chinnuswamy
Source:
Analytical methods 2017 v.9 no.48 pp. 6791-6800
ISSN:
1759-9679
Subject:
analytical methods; ascorbic acid; blood serum; carbon nanotubes; cysteine; dopamine; electrochemistry; glassy carbon electrode; graphene; hypoxanthine; iron; nanogold; nickel; oxidation; pH; phosphates; silver; silver chloride; soot; surface area; uric acid; xanthine
Abstract:
... The detection of thiol-containing amino acids, particularly l-cysteine (l-CySH), without any interference from other biochemicals is a challenging research interest in electroanalytical chemistry. Amongst various electrodes, the nanogold modified electrode has been reported to be effective for low potential electrochemical oxidation (∼0 V vs. Ag/AgCl) and sensing of l-CySH. Herein, we report a con ...
DOI:
10.1039/c7ay02251d

11. TiO₂/CdS nanorod array-based photoelectrochemical sensing of Cu²⁺ in human serum samples

Author:
Feng, Kejun; Yang, Minghui; Xie, Fang; Diao, Guiqiang; Ou, Mingming; Huang, Huanfeng
Source:
Analytical methods 2017 v.9 no.48 pp. 6754-6759
ISSN:
1759-9679
Subject:
analytical methods; blood serum; copper; energy efficiency; glass; nanoparticles; nanorods; tin dioxide; titanium dioxide
Abstract:
... In this study, we report a sensitive and selective photoelectrochemical sensor for the detection of Cu²⁺ in human serum samples based on a TiO₂/CdS nanorod array. To prepare the sensor, a TiO₂ nanorod array was initially deposited onto a fluorine-doped tin oxide (FTO) conductive glass, and then, CdS nanoparticles were deposited onto the TiO₂ nanorod array surface. The well-matched energy level bet ...
DOI:
10.1039/c7ay02625k

12. Application of a glassy carbon electrode modified with carbon black nanoparticles for highly sensitive voltammetric determination of quetiapine

Author:
Ławrywianiec, M.; Smajdor, J.; Paczosa-Bator, B.; Piech, R.
Source:
Analytical methods 2017 v.9 no.47 pp. 6662-6668
ISSN:
1759-9679
Subject:
analytical methods; calibration; drugs; electrochemistry; fumarates; glassy carbon electrode; nanoparticles; soot; standard deviation; urine
Abstract:
... A novel highly sensitive voltammetric quetiapine fumarate (QF) sensor based on a glassy carbon electrode (GCE) modified with carbon black nanoparticles (CB) was successfully developed. The electrochemical behaviour of the modified electrode and electrooxidation of quetiapine were investigated using cyclic voltammetry. The influence of the instrumental conditions and possible interfering substances ...
DOI:
10.1039/c7ay02140b

13. CaCO₃ nanoparticles as the tags for potentiometric detection of a cardiac biomarker using a calcium ion-selective electrode

Author:
Fu, Xiaohong; Xu, Kun; Feng, Xueyu; Chang, Bo; Yang, Fan; Huang, Rong
Source:
Analytical methods 2017 v.9 no.47 pp. 6609-6612
ISSN:
1759-9679
Subject:
analytical methods; biomarkers; bovine serum albumin; calcium; calcium carbonate; myocardial infarction; myoglobin; nanoparticles; specific ion electrodes
Abstract:
... A novel potentiometric immunosensing protocol was developed for the detection of myoglobin (a cardiac biomarker for acute myocardial infarction), using bovine serum albumin (BSA)-functionalized calcium carbonate (CaCO₃) nanoparticles as the signal-generation tags and using a calcium ion-selective electrode. ...
DOI:
10.1039/c7ay01949a

14. CVD graphene incorporating polymerized l-cysteine as an electrochemical sensing platform for simultaneous determination of dopamine and ascorbic acid

Author:
He, Danyu; Li, Shehong; Zhang, Pu; Luo, Hongxia
Source:
Analytical methods 2017 v.9 no.47 pp. 6689-6697
ISSN:
1759-9679
Subject:
analytical methods; ascorbic acid; copper; cysteine; detection limit; dopamine; electrochemistry; electrodes; graphene; oxidation; polyethylene terephthalates; sensors (equipment); vapors
Abstract:
... A graphene platform electrode (GPE) was prepared directly by transferring chemical vapor deposited (CVD) graphene films from Cu foils to polyethylene terephthalate substrates with the aid of polymethyl-methacrylate, a distinct advantage over previously developed methods. l-Cysteine (l-Cys) was polymerized on the GPE by using a one-step electrodeposition technique to form a poly-l-Cys/GPE. As a neg ...
DOI:
10.1039/c7ay02489d

15. Highly dispersed palladium nanoparticles generated in situ on layered double hydroxide nanowalls for ultrasensitive electrochemical detection of hydrazine

Author:
Xu, Liang; Qu, Zongkai; Chen, Jun; Chen, Xu; Li, Feng; Yang, Wensheng
Source:
Analytical methods 2017 v.9 no.47 pp. 6629-6635
ISSN:
1759-9679
Subject:
active sites; analytical methods; cobalt; electrochemistry; electrodes; hot water treatment; hydrazine; indium tin oxide; nanoparticles; nanosheets; oxidation; palladium; sensors (equipment)
Abstract:
... Rational design and fabrication of electrocatalytic nanomaterials is an effective approach for improving the sensitivity and stability of electrochemical sensors. Here, we report a novel CoAl-layered double hydroxide nanowall-supported Pd nanoparticle (PdNP/CoAl-LDHNW) composite as an electrochemical sensing platform for highly sensitive and durable detection of hydrazine. CoAl-LDHNWs, composed of ...
DOI:
10.1039/c7ay02324c

16. Lysozyme-stabilized bimetallic gold/silver nanoclusters as a turn-on fluorescent probe for determination of ascorbic acid and acid phosphatase

Author:
Pang, Shu; Liu, Siyu
Source:
Analytical methods 2017 v.9 no.47 pp. 6713-6718
ISSN:
1759-9679
Subject:
acid phosphatase; analytical methods; aqueous solutions; ascorbic acid; fluorescence; fluorescent dyes; gold; hydrolysis; lysozyme; nanosilver; pH; reducing agents
Abstract:
... Bimetallic gold/silver nanoclusters were synthesized in aqueous solution with lysozyme as a stabilizing and reducing agent. The prepared lysozyme-stabilized gold/silver nanoclusters (Lys-Au/Ag NCs) displayed highly near-infrared fluorescence and excellent stability under various pH values and ionic environments. We found that ascorbic acid (AA) significantly enhanced the fluorescence of Lys-Au/Ag ...
DOI:
10.1039/c7ay02372c

17. Method to study particle flow bias at a channel bifurcation in a microfluidic device

Author:
Lake, Melinda A.; Berry, Seth A.; Hoelzle, David J.
Source:
Analytical methods 2017 v.9 no.47 pp. 6719-6724
ISSN:
1759-9679
Subject:
algorithms; analytical methods; empirical research; polystyrenes; processing chemistry; statistical analysis; statistical models
Abstract:
... Cell and particle sorting mechanisms are integral components in many microfluidic devices for cell and chemical processing. The objective of a microfluidic particle sorter is to separate a target particle sub-population with a 100% true positive and true negative rate. Sorter performance is not perfect in practice; however, negative outcomes in a good sorter design are relatively rare and thus sta ...
DOI:
10.1039/c7ay02224g

18. pH-controlled fluorescence changes in a novel semiconducting polymer dot/pyrogallic acid system and a multifunctional sensing strategy for urea, urease, and pesticides

Author:
Huang, Hui; Li, Jiao; Liu, Mengxian; Wang, Zizhun; Wang, Bingdi; Li, Meini; Li, Yongxin
Source:
Analytical methods 2017 v.9 no.47 pp. 6669-6674
ISSN:
1759-9679
Subject:
analytical methods; detection limit; dimethoate; enzyme activity; enzyme inhibition; fluorescence; fruits; moieties; pH; polymers; quinones; urea; urease; vegetables
Abstract:
... A novel multifunctional semiconducting polymer dot (Pdots)/pyrogallic acid (PA) system was successfully established for fluorescence sensing of urea, urease, and pesticides. The Pdots/PA system was pH controllable, emitting strong fluorescence at pH 6.0. However, in an alkaline environment, PA transformed into its quinone structure, which is an efficient fluorescence quencher, resulting in fluores ...
DOI:
10.1039/c7ay02284k

19. Sensitive and reliable paper-based glucose sensing mechanisms with smartphone readout using the L*a*b* color space

Author:
Baş, Deniz
Source:
Analytical methods 2017 v.9 no.47 pp. 6698-6704
ISSN:
1759-9679
Subject:
Prunus cerasus; analytical methods; color; computer software; computers; detection limit; glucose; honey; image processors; iodine; mobile telephones; nectar; quantitative analysis; quinones
Abstract:
... Paper-based assay platforms play an important role among rapid test methods. It is essential to combine these promising platforms with smartphones which make on-site analysis possible without using external image processors. In this study, the performance of paper-based glucose assay methods was investigated by using the L*a*b* color space as the quantitative measurement. For this purpose, two glu ...
DOI:
10.1039/c7ay02124k

20. The adsorption behavior and mechanism of perfluorochemicals on oxidized fluorinated graphene sheets supported on silica

Author:
Li, Fan; Wei, Weili; Gao, Die; Xia, Zhining
Source:
Analytical methods 2017 v.9 no.47 pp. 6645-6652
ISSN:
1759-9679
Subject:
acidity; adsorbents; adsorption; analytical methods; anion exchange; chemical species; fatty acids; graphene; hydrophobicity; oxidation; pH; perfluorocarbons; silica; solid phase extraction
Abstract:
... This is the first report on the fabrication of oxidized fluorinated graphene sheets supported on silica (OFG@silica) for the selective adsorption of perfluorochemicals (PFCs). To increase the affinity towards PFCs, oxidized fluorinated graphene (OFG) was grafted onto amino-terminated alkyl chain modified silica (NH₂-silica), thus producing a mixed-mode material combining fluorophilicity and hydrop ...
DOI:
10.1039/c7ay02070h

21. Determination of alizarin red S based on layered double hydroxides-improved chemiluminescence from hydrogen peroxide and luminol

Author:
Pan, Feng; Zhang, Yilin; Yuan, Zhiqin; Lu, Chao
Source:
Analytical methods 2017 v.9 no.46 pp. 6468-6473
ISSN:
1759-9679
Subject:
adsorption; alizarin; analytical methods; anions; carbonates; chemiluminescence; detection limit; dyes; free radicals; hydrogen peroxide; hydroxides; metal ions; wastewater
Abstract:
... In this report, a simple chemiluminescence (CL) approach for detecting an anionic dye, alizarin red S (ARS), based on layered double hydroxides (LDHs)-improved CL from hydrogen peroxide (H₂O₂) and luminol system is proposed. The LDHs-improved H₂O₂–luminol CL is due to the adsorption of luminol dianion and peroxide anion onto the positively charged brucite-like layers and the facilitated formation ...
DOI:
10.1039/c7ay02405c

22. Dual signal amplification strategy for electrochemical detection of platelet-derived growth factor BB

Author:
Xie, Bin; Zhou, Ning; Ding, Rong; Zhao, Yuanchao; Zhang, Bohan; Li, Ting; Yang, Minghui
Source:
Analytical methods 2017 v.9 no.46 pp. 6569-6573
ISSN:
1759-9679
Subject:
alkaline phosphatase; analytical methods; antibodies; antigens; biomarkers; blood serum; carbon nanotubes; detection limit; electric potential difference; electrochemistry; glassy carbon electrode; immunosensors; ions; models; molybdates; neoplasms; oligonucleotides; phosphates; platelet-derived growth factor; silver; silver chloride
Abstract:
... The authors report a dual signal amplification strategy for improving the sensitivity of an electrochemical immunosensor. Single-walled carbon nanotubes (SCNTs) served as supports for aptamers and alkaline phosphatase (ALP), and then the modified SCNTs were utilized as electrochemical probes. The aptamer contains phosphate groups, while ALP can hydrolyse one molecular pyrophosphate into two molecu ...
DOI:
10.1039/c7ay02513k

23. Facile and sensitive detection of clenbuterol in pork using a personal glucose meter

Author:
Li, Fang; Zhang, Ruihua; Kang, Huaibin; Hu, Yonggang; Liu, Yunhong; Zhu, Junya
Source:
Analytical methods 2017 v.9 no.46 pp. 6507-6512
ISSN:
1759-9679
Subject:
analytical methods; antibodies; beta-fructofuranosidase; catalytic activity; clenbuterol; drugs; glucose; gold; hydrolysis; liver; livestock; magnetism; nanogold; pork; serum albumin; sucrose
Abstract:
... Clenbuterol (CLB) is a β-agonist drug that is illegally added as a growth-promoting agent in livestock. In this study, a facile and sensitive method for the detection of CLB using a personal glucose meter (PGM) was reported. Clenbuterol–bovine serum albumin functionalized magnetic beads were used to compete with CLB for binding to its corresponding antibody and gold nanoparticle–invertase–secondar ...
DOI:
10.1039/c7ay01826f

24. A new analytical technique for the extraction and quantification of microplastics in marine sediments focused on easy implementation and repeatability

Author:
Sánchez-Nieva, Julio; Perales, José Antonio; González-Leal, Juan Maria; Rojo-Nieto, Elisa
Source:
Analytical methods 2017 v.9 no.45 pp. 6371-6378
ISSN:
1759-9679
Subject:
air; analytical methods; confocal microscopy; laboratory equipment; marine sediments; microparticles; microplastics; mixing; polyethylene; sodium chloride; zinc chloride
Abstract:
... A new analytical approach has been developed to extract and quantify HDPE microparticles from marine sediments. This is the first method that has been proposed using routine laboratory equipment that incorporates slow mixing and air flux for floatation in order to collect the supernatant by overflow, using NaCl saturated solutions. The technique developed in this study comprised the preparation of ...
DOI:
10.1039/c7ay01800b

25. A one-step rapid screening test of Listeria monocytogenes in food samples using a real-time loop-mediated isothermal amplification turbidity assay

Author:
Wachiralurpan, Sirirat; Sriyapai, Thayat; Areekit, Supatra; Sriyapai, Pichapak; Thongphueak, Dueantem; Santiwatanakul, Somchai; Chansiri, Kosum
Source:
Analytical methods 2017 v.9 no.45 pp. 6403-6410
ISSN:
1759-9679
Subject:
DNA; Listeria monocytogenes; analytical methods; detection limit; loop-mediated isothermal amplification; magnesium; rapid methods; raw chicken meat; screening; turbidity
Abstract:
... A rapid and specific, hly-based, loop-mediated isothermal amplification (LAMP) was applied for the detection of Listeria monocytogenes in food and food products, using a real-time turbidimeter platform (LAMP-turbidity). The principle behind this method relies on an increase in a DNA yield, which correlates with the production of magnesium pyrophosphate, and the results can be determined via an amp ...
DOI:
10.1039/c7ay01750b

26. A simple technique to design microfluidic devices for system integration

Author:
Yang, Mimi X.; Wang, Benjamin; Hu, Xiaolin; Wong, H.-S. Philip
Source:
Analytical methods 2017 v.9 no.45 pp. 6349-6356
ISSN:
1759-9679
Subject:
analytical methods; electronic circuits; polydimethylsiloxane
Abstract:
... We present a robust method to fabricate a polydimethylsiloxane (PDMS) microfluidic device with critical channel features located near the periphery. The fabricated device has a window cutout, allowing close placement and integration of the channel with solid state circuits and devices. The flow characteristics of the fabricated device are shown to closely follow that of theoretical behavior, makin ...
DOI:
10.1039/c7ay02177a

27. Selective analysis of epinephrine in the presence of uric acid by using an amplified electrochemical sensor employing a gold nanoparticle decorated cysteic acid film

Author:
Karim-Nezhad, G.; Khorablou, Z.
Source:
Analytical methods 2017 v.9 no.45 pp. 6394-6402
ISSN:
1759-9679
Subject:
analytical methods; chemical species; cysteic acid; detection limit; electrochemistry; electron transfer; electrons; epinephrine; glassy carbon electrode; nanogold; oxidation; scanning electron microscopy; sensors (equipment); surface area; uric acid
Abstract:
... In the present work, an effective electrochemical sensor for the rapid and selective determination of epinephrine (EP) in the presence of uric acid (UA) based on a glassy carbon electrode (GCE) modified with gold nanoparticles (AuNPs) and cysteic acid was applied. This modified electrode exhibited a potent and persistent electron mediating behavior followed by well separated oxidation peaks of EP ...
DOI:
10.1039/c7ay02312j

28. A highly selective Schiff base fluorescent chemosensor for Lu³⁺

Author:
Wang, Lina; Tang, Juanjuan; Sui, Ning; Yang, Xing; Zhang, Luyao; Yao, Xiaojun; Zhou, Qinfei; Xiao, Hailian; Kuang, Shaoping; Yu, William W.
Source:
Analytical methods 2017 v.9 no.44 pp. 6254-6260
ISSN:
1759-9679
Subject:
analytical methods; chelation; fluorescence; schiff bases
Abstract:
... A Schiff base derivative, N-(3-methoxy-4-hydroxybenzylidene)salicyloylhydrazone (L), shows high selectivity to Lu³⁺ not only in abiotic systems but also in living cells with fluorescence. The presence of PVP can increase the fluorescence intensity. The fluorescence enhancement is presumably due to a combinational effect of intramolecular charge transfer (ICT) and excited-state intra/intermolecular ...
DOI:
10.1039/c7ay01808h

29. An ultrasensitive sandwich immunoassay with a glucometer readout for portable and quantitative detection of Cronobacter sakazakii

Author:
Ye, Lingxian; Zhao, Guangying; Dou, Wenchao
Source:
Analytical methods 2017 v.9 no.44 pp. 6286-6292
ISSN:
1759-9679
Subject:
Cronobacter sakazakii; analytical methods; antibodies; electrochemistry; glucose; glucose oxidase; immunoassays; infant formulas; magnetism; nanoparticles; point-of-care testing; silica
Abstract:
... Developing portable and low-cost methods for quantitative detection of Cronobacter sakazakii (C. sakazakii) from powdered infant formula plays a significant role in controlling and preventing a range of serious neonatal infections. Here, we reported a novel methodology for C. sakazakii detection using a low-cost, simple, and widely accessible personal glucose meter (PGM) as the readout. The electr ...
DOI:
10.1039/c7ay02222k

30. A selective nanosensor for ultrafast detection of Cu²⁺ ions based on C5 DNA-templated gold nanoclusters and Fenton-like reaction

Author:
Qing, Taiping; Bu, Hongchang; He, Xiaoxiao; He, Dinggeng; Zhou, Bing; Sun, Huanhuan; Jia, Ruichen; Ma, Wenjie; Wang, Kemin
Source:
Analytical methods 2017 v.9 no.44 pp. 6222-6227
ISSN:
1759-9679
Subject:
acid mine drainage; aerobic conditions; analytical methods; ascorbic acid; biosensors; blood sampling; copper; copper deficiency; fluorescence; hydrogen peroxide; hydroxyl radicals; ions; liver; monitoring; nanogold; oxidative stress; oxygen; pollution
Abstract:
... Copper pollution has become a very serious problem in modern society with the increasing industrial emission and the acid mine drainage. Copper deficiency or excess copper accumulation in human and animal livers can bring both oxidative stress and severe disorders. Thus, the development of a simple and efficient strategy for Cu²⁺ ion detection in water and blood samples is very necessary and meani ...
DOI:
10.1039/c7ay02247f

31. Development of an enzyme cycling method by a purine nucleoside phosphorylase for assaying inorganic phosphate

Author:
Ueda, Shigeru; Sakasegawa, Shin-ichi
Source:
Analytical methods 2017 v.9 no.44 pp. 6235-6239
ISSN:
1759-9679
Subject:
Bacillus (bacteria); analytical methods; creatine kinase; guanine; inosine; phosphates; phosphorylase; xanthine dehydrogenase
Abstract:
... We have developed a novel enzymatic cycling method that uses purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) from Bacillus sp. to measure inorganic phosphate. The method utilizes the reversibility of the PNP reaction, in which the forward and reverse reactions are catalyzed in the presence of an excess amount of inosine and guanine, respectively, a principle similar to that previously demonstra ...
DOI:
10.1039/c7ay02016c

32. Electrochemical nanostructure platform for the analysis of glutathione in the presence of uric acid and tryptophan

Author:
Karimi-Maleh, Hassan; Bananezhad, Asma; Ganjali, Mohammad R.; Norouzi, Parviz
Source:
Analytical methods 2017 v.9 no.44 pp. 6228-6234
ISSN:
1759-9679
Subject:
analytical methods; carbon electrodes; electrochemistry; glutathione; nanocomposites; nanomaterials; tryptophan; uric acid
Abstract:
... In this work, a NiO–CNT nanocomposite and 2-(3,4-dihydroxyphenethyl)isoindoline-1,3-dione (DPID) were used as modifiers for the modification of a carbon paste electrode (DPID/NiO–CNT/CPE) for the electro-catalytic analysis of glutathione (GSH). The electro-catalytic interaction between DPID and GSH on the surface of the DPID/NiO–CNT/CPE was used as a new way for the analysis of GSH. GSH can be det ...
DOI:
10.1039/c7ay02057k

33. An effective signal enhancement strategy for sensing cysteine based on aluminium-initiated emission

Author:
Zou, Wu; Chen, Xuejiao; Huan, Cheng; Gu, Tingting; Xia, Jiaoyun; Chen, Can; Gong, Fuchun
Source:
Analytical methods 2017 v.9 no.43 pp. 6155-6160
ISSN:
1759-9679
Subject:
aluminum; analytical methods; blood serum; chelation; cysteine; detection limit; fluorescence; image analysis; ions; moieties
Abstract:
... An efficient signal enhancement strategy for the detection of cysteine (Cys) was developed, which is based on the combination of a Cys-reduced reaction and the chelation of Al³⁺ with the Cys-promoted product. The Cys probe S-DPM was prepared by adding a 2,4-dinitrobenzenesulfonyl group onto a 2′-hydroxyldihydropyrimidobenzimidazole derivative (DPM). Upon treatment with Cys, S-DPM was reduced and t ...
DOI:
10.1039/c7ay02026k

34. pH-Sensing fluorescence oligonucleotide probes based on an i-motif scaffold: a review

Author:
Dembska, Anna; Bielecka, Patrycja; Juskowiak, Bernard
Source:
Analytical methods 2017 v.9 no.43 pp. 6092-6106
ISSN:
1759-9679
Subject:
analytical methods; cell membranes; cytosine; fluorescence; monitoring; oligonucleotide probes; pH; protons
Abstract:
... Fluorescence-based approaches have found widespread applications in cell biology. pH-Sensing using fluorescent i-motifs is a potentially useful strategy for real-time, in vivo monitoring of important cellular processes. i-Motif scaffolds can serve as the recognition element for H⁺ and are highly programmable, which leads to probes that exhibit different dynamic pH ranges and possess slightly diffe ...
DOI:
10.1039/c7ay01942d

35. SmartIHC-Analyzer: smartphone assisted microscopic image analytics for automated Ki-67 quantification in breast cancer evaluation

Author:
Tewary, Suman; Arun, Indu; Ahmed, Rosina; Chatterjee, Sanjoy; Chakraborty, Chandan
Source:
Analytical methods 2017 v.9 no.43 pp. 6161-6170
ISSN:
1759-9679
Subject:
analytical methods; automation; breast neoplasms; cell proliferation; color; computer software; diagnostic techniques; human cell lines; image analysis; immunohistochemistry; lighting; microscopy; mobile telephones; neoplasm cells; point-of-care systems; protein synthesis
Abstract:
... As with other cancers, cell proliferation is one of the indicative hallmarks of breast cancer evaluation. The expression of human Ki-67, being a nuclear protein, has strong association with the proliferation of cancer cells. The proliferation index from Ki-67 is evaluated by immunohistochemical (IHC) study by discriminating positively (brown color) and negatively (blue color) stained nuclei of cel ...
DOI:
10.1039/c7ay02302b

36. CNT-anchored cellulose fluorescent nanofiber membranes as a fluorescence sensor for Cu²⁺ and Cr³⁺

Author:
Gu, Yao; Wang, Meiling; Li, Guizhen
Source:
Analytical methods 2017 v.9 no.42 pp. 6044-6048
ISSN:
1759-9679
Subject:
analytical methods; aqueous solutions; byproducts; carbon; cellulose; chromium; copper; detection limit; environmental monitoring; fluorescence; fluorescent dyes; lakes; nanofibers; porous media; quinones; sorption; surface area
Abstract:
... 1,4-Dihydroxyanthraquinone (1,4-DHAQ, a fluorophore) doped carbon nanotubes@cellulose (1,4-DHAQ-doped CNTs@CL) nanofibrous membranes have been prepared via electrospinning and subsequent deacetylation in this work. They have been successfully applied for highly sensitive detection of Cu²⁺ in aqueous solution. The surface area per unit mass (S/M) ratio of the nanofibrous membranes was enhanced by i ...
DOI:
10.1039/c7ay01994g

37. Is measurement uncertainty from sampling related to analyte concentration?

Author:
Ellison, Stephen L. R.; Ramsey, Michael H.; Lawrance, Paul; Stuart, Brian; Minguez, Jesus; Walker, Michael J.
Source:
Analytical methods 2017 v.9 no.42 pp. 5989-5996
ISSN:
1759-9679
Subject:
analytical methods; data collection; food industry; foods; standard deviation; uncertainty; variance
Abstract:
... The contribution of sampling to the combined uncertainty of measurement is assessed using a combination of literature review and experimental determination of sampling variability in a range of foodstuffs in order to determine whether there is a consistent relationship between analyte level and proportion of variation attributable to sampling. Experimental determinations used the duplicate method, ...
DOI:
10.1039/c7ay00752c

38. Microprofiling real time nitric oxide flux for field studies using a stratified nanohybrid carbon–metal electrode

Author:
Chaturvedi, P.; Vanegas, D. C.; Hauser, B. A.; Foster, J. S.; Sepúlveda, M. S.; McLamore, E. S.
Source:
Analytical methods 2017 v.9 no.42 pp. 6061-6072
ISSN:
1759-9679
Subject:
alginates; analytical methods; bacteria; catalysts; chitosan; data collection; deterministic models; diffusivity; electrodes; field experimentation; graphene oxide; homeostasis; hydrophobicity; invertebrates; nanohybrids; nitric oxide; polymers; stress response; tissues
Abstract:
... Nitric oxide (NO) is an important signaling molecule that is involved in stress response, homeostasis, host defense, and cell development. In most cells, NO levels are in the femtomolar to micromolar range, with extracellular concentrations being much lower. Thus, real time measurement of spatiotemporal NO dynamics near the surface of living cells/tissues is a major challenge. Here, we report the ...
DOI:
10.1039/c7ay01964e
CHORUS:
10.1039/c7ay01964e

39. Storage and controlled release of fragrances maintaining a constant ratio of volatile compounds

Author:
Silina, Y. E.; Tillotson, J. R.; Manz, A.
Source:
Analytical methods 2017 v.9 no.42 pp. 6073-6082
ISSN:
1759-9679
Subject:
analytical methods; biochemistry; models; odors; oils; psychophysiology; temperature; volatile organic compounds
Abstract:
... Controlled fragrance release at the right time, in the right place, depending on the context remains a technological challenge in the areas of psychophysiology, biochemistry and the entertainment industry. In this study, we demonstrate how bulk poly(dimethylsiloxane) (PDMS) templates may effectively take up and retain volatile organic compounds of essential orange oil in the original form without ...
DOI:
10.1039/c7ay01799e

40. Correction: Target-induced duplex–triplex transition for ratiometric detection of adenosine triphosphate

Author:
Yao, Shujuan; Gao, Yanhua; Wang, Wen; Ni, Donghua; Zhang, Kaixian; Li, Ling; Du, Jianqiang; Cui, Xiujuan
Source:
Analytical methods 2017 v.9 no.41 pp. 5980
ISSN:
1759-9679
Subject:
adenosine triphosphate; analytical methods; biosensors
Abstract:
... Correction for ‘Target-induced duplex–triplex transition for ratiometric detection of adenosine triphosphate’ by Shujuan Yao et al., Anal. Methods, 2017, 9, 3244–3248. ...
DOI:
10.1039/c7ay90139a

41. Visual determination of ferric ions in aqueous solution based on a high selectivity and sensitivity ratiometric fluorescent nanosensor

Author:
Wu, Haolan; Yang, Lian; Chen, Linfeng; Xiang, Fang; Gao, Hongyu
Source:
Analytical methods 2017 v.9 no.41 pp. 5935-5942
ISSN:
1759-9679
Subject:
United States Environmental Protection Agency; analytical methods; aqueous solutions; biosensors; color; detection limit; drinking water; fluorescence; ions; iron; nanohybrids; nanospheres; rhodamines; silica; wavelengths
Abstract:
... A novel ratiometric fluorescent nanosensor for visual sensing of Fe³⁺ has been developed by integrating yellow-emissive rhodamine derivatives (RhB) onto the surface of silica nanospheres embedded with red CdTe QDs. Such a nanohybrid fluorescent sensor, RhB–CdTe@SiO₂ QDs, displays two distinct emission peaks 556 nm and 651 nm under a single excitation wavelength in the presence of Fe³⁺. The yellow ...
DOI:
10.1039/c7ay01917c

42. Are my data normal?

Author:
Analytical Methods Committee AMCTB No. 82,
Source:
Analytical methods 2017 v.9 no.40 pp. 5847-5850
ISSN:
1759-9679
Subject:
analytical methods; bias; data collection; normal distribution
Abstract:
... Many inferences from statistical methods use the assumption that experimental data form a random sample (using that word in the statistical, not the chemical or physical, sense) from a population with a normal (Gaussian) distribution of measurement errors or other variations. In most cases this assumption is not actually tested, so if it is not valid false deductions may be made from the data. Thi ...
DOI:
10.1039/c7ay90126g

43. Box–Behnken design applied to optimize the ultrasound-assisted extraction of petroleum biomarkers in river sediment samples using green analytical chemistry

Author:
Araujo, Fausto M.; Santos, Mellina D. R.; de Oliveira, Marcone A. L.; Matos, Renato C.; Matos, Maria. A. C.
Source:
Analytical methods 2017 v.9 no.40 pp. 5859-5867
ISSN:
1759-9679
Subject:
acetone; analytical chemistry; analytical methods; biomarkers; detection limit; experimental design; hexane; isoprenoids; petroleum; rivers; sediments; solvents; sonication; spectrometers; ultrasonic treatment
Abstract:
... In the present paper, the 3³ Box–Behnken design with a triplicate central point was used to optimize the conditions for the ultrasound-assisted extraction of n-alkanes (C10–C40) and isoprenoids (phytane and pristane), which are petroleum biomarkers and their derivatives, in river sediment samples. The determination was carried out using a Gas Chromatographer/Mass Spectrometer (GC/MS). The factors ...
DOI:
10.1039/c7ay01470h

44. Electrochemical sensing of estradiol benzoate using hydroxyapatite with three-dimensional channel frameworks

Author:
Wen, Yu; Cui, Jing; Shao, Bei; Cheng, Zouting; Wang, Liuzheng; Banks, Craig E.; Zhang, Ying
Source:
Analytical methods 2017 v.9 no.40 pp. 5868-5872
ISSN:
1759-9679
Subject:
analytical methods; electrochemistry; electron transfer; estradiol; hydroxyapatite; metastasis; neoplasms; pollutants
Abstract:
... Ubiquitous estradiol benzoate (17β-estradiol-3-benzoate) in the environment and daily life has become a hot issue in society since it has been proven to be closely associated with metastatic tumour formation. In the current work, hydroxyapatite with three-dimensional channel frameworks has been successfully demonstrated to be highly sensitive for the electroanalytical sensing of this pollutant, wi ...
DOI:
10.1039/c7ay01790a

45. Hierarchical Co(OH)₂ nanotube arrays grown on carbon cloth for use in non-enzymatic glucose sensing

Author:
Huang, M.; Luo, X.; He, D.; Jiang, P.
Source:
Analytical methods 2017 v.9 no.40 pp. 5903-5909
ISSN:
1759-9679
Subject:
analytical methods; anion exchange; blood serum; carbon; carbonates; cobalt; glucose; nanotubes; nanowires
Abstract:
... Hierarchical Co(OH)₂ nanotube arrays grown on carbon cloth (Co(OH)₂ NTAs/CC) were prepared by a simple two-step approach. Firstly, the layered cobalt carbonate hydroxide nanowire arrays grown on carbon cloth (LCCH NWAs/CC) were prepared by chemical bath deposition. Then, the obtained LCCH NWAs/CC was converted to Co(OH)₂ nanotube arrays supported on CC (Co(OH)₂ NTAs/CC) through an anion-exchange r ...
DOI:
10.1039/c7ay01991b

46. Should analytical chemists (and their customers) trust the normal distribution?

Author:
Thompson, Michael
Source:
Analytical methods 2017 v.9 no.40 pp. 5843-5846
ISSN:
1759-9679
Subject:
analytical methods; bias; data quality; normal distribution; socioeconomics
Abstract:
... The normal distribution, under its popular name ‘the bell curve’, has attracted adverse criticism in recent years, owing mainly to being prominently featured in some well-publicised books on socio-economic topics. A number of conclusions in these fields, ranging from questionable to spectacularly incorrect, have been drawn from an ill-considered use of the bell curve as a statistical tool. Those a ...
DOI:
10.1039/c7ay90138k

47. A 3-step chemiluminescence method for chemical oxygen demand measurement with dichromate oxidizing reagent

Author:
Hue, Do Thi Kim; Shiba, Takumi; Maeda, Yasuaki; Takenaka, Norimichi
Source:
Analytical methods 2017 v.9 no.39 pp. 5797-5805
ISSN:
1759-9679
Subject:
analytical methods; ascorbic acid; chemical oxygen demand; chemiluminescence; chromium; copper; detection limit; gallic acid; heat; hydrogen; iron; magnesium; manganese; metal ions; phenol; phthalates; potassium; pyrocatechol; pyrogallol; river water; silver
Abstract:
... In this study, the use of potassium dichromate as an oxidizing reagent in the 3-step chemiluminescence (CL) chemical oxygen demand (COD) method, based on the principle of the permanganate COD (CODMₙ) method (JIS K0102), was developed (3-step CL CODCᵣ method). The sample reacted with an excess of dichromate under heating, and the remaining dichromate was neutralized by a reducing organic compound. ...
DOI:
10.1039/c7ay01652b

48. Effects of organic solvents on immunosensing assays for small molecules based on an optofluidic immunosensing platform

Author:
Lou, Xuening; Zhu, Anna; Luo, Qiang; Zhang, Yan; Long, Feng
Source:
Analytical methods 2017 v.9 no.39 pp. 5731-5740
ISSN:
1759-9679
Subject:
acetone; acetonitrile; aflatoxin M1; analytical methods; antibodies; hexane; immunoassays; immunosensors; methanol; solubility; solvents
Abstract:
... Highly sensitive and selective immunosensors are widely applied to detect small molecules. Organic solvent extraction of small molecules in samples is generally required when the small molecules have poor solubility in water. Immunosensing assays should tolerate at least some organic solvents to rapidly detect small molecules on-site. Herein, the effects of four organic solvents (methanol, acetone ...
DOI:
10.1039/c6ay03373c

49. Inverse opals of photonic crystal hydrogels for selective sensing of lead ions

Author:
Liu, Shirong; Qin, Liyan; Ni, Zhongbin; Chen, Mingqing
Source:
Analytical methods 2017 v.9 no.39 pp. 5791-5796
ISSN:
1759-9679
Subject:
acrylamides; analytical methods; cadmium; color; composite polymers; copper; hydrogels; ionic strength; ions; lead; monitoring; nickel; pH; photons; porous media; zinc
Abstract:
... Acrylamide (AM) and hydroxyethyl methacrylate (HEMA) copolymer based inverse opals of photonic crystal hydrogels (PCHs) were fabricated by using the colloidal crystal template method. The effects of pH, ionic strength and compositions on the response properties of PCHs were investigated. The resultant PCHs with a highly ordered three-dimensional interconnected macroporous structure exhibited high ...
DOI:
10.1039/c7ay01887h

50. Magnetic tweezers for the mechanical research of DNA at the single molecule level

Author:
Xin, Qi; Li, Peng; He, Yuning; Shi, Cuiping; Qiao, Yiqun; Bian, Xiaojun; Su, Jing; Qiao, Ruirui; Zhou, Xinbo; Zhong, Jian
Source:
Analytical methods 2017 v.9 no.39 pp. 5720-5730
ISSN:
1759-9679
Subject:
DNA; analytical methods; biomechanics; cations; drugs; enzymes; magnetism; mechanical properties; organic compounds; structural proteins
Abstract:
... Biomechanical forces are involved in the physiological function of molecules. Single molecule magnetic tweezers have been developed and used to investigate the mechanical properties of individual biomolecules and their interactions. In this review, we will mainly review the application of magnetic tweezers for the mechanical research of DNA at the single molecule level. Firstly, we will briefly in ...
DOI:
10.1039/c7ay01495c

51. Analysis of deferiprone in exhaled breath condensate using silver nanoparticle-enhanced terbium fluorescence

Author:
Mohamadian, Esmail; Shayanfar, Ali; Khoubnasabjafari, Maryam; Jouyban-Gharamaleki, Vahid; Ghaffary, Saba; Jouyban, Abolghasem
Source:
Analytical methods 2017 v.9 no.38 pp. 5640-5645
ISSN:
1759-9679
Subject:
analytical methods; condensates; drugs; fluorescence; monitoring; nanosilver; pH; patients; silver; terbium; therapeutics
Abstract:
... Exhaled breath condensate (EBC) has been proposed as an alternative non-invasive biological sample for therapeutic drug monitoring. In this study, a sensitive method for the quantification of deferiprone (DEF) in EBC samples was developed using a silver nanoparticle (AgNP)-enhanced terbium (Tb³⁺) fluorescence method. Fluorescence properties of the Tb³⁺–DEF complex were studied in the presence of A ...
DOI:
10.1039/c7ay01715d

52. A rapid and sensitive turn-on fluorescent probe for ascorbic acid detection based on carbon dots–MnO₂ nanocomposites

Author:
Hu, Yalei; Zhang, Lin; Geng, Xin; Ge, Jia; Liu, Haifang; Li, Zhaohui
Source:
Analytical methods 2017 v.9 no.38 pp. 5653-5658
ISSN:
1759-9679
Subject:
analytical methods; ascorbic acid; biochemical pathways; biocompatibility; carbon; detection limit; energy transfer; fluorescence; fluorescent dyes; manganese; manganese dioxide; nanocomposites; nanosheets
Abstract:
... Ascorbic acid (AA) is a significant small biomolecule and plays a key role in many biochemical processes. In this work, a rapid turn-on fluorescent probe was developed for sensitive and selective sensing of AA based on carbon dots–MnO₂ nanocomposites. The nanocomposites were constructed by in situ synthesis of MnO₂ nanosheets in carbon dot (C-dot) solution, and the fluorescence of C-dots was quenc ...
DOI:
10.1039/c7ay01710c

53. A supercharged fluorescent protein based FRET sensing platform for detection of heparin contamination

Author:
Ding, Yubin; Zhou, Min; Wei, Hui
Source:
Analytical methods 2017 v.9 no.38 pp. 5593-5597
ISSN:
1759-9679
Subject:
analytical methods; biosensors; chondroitin sulfate; green fluorescent protein; heparin; heparin lyase
Abstract:
... Development of biosensors for the detection of oversulfated chondroitin sulfate (OSCS), the key contaminant in heparin (Hep), is a greatly demanding but challenging task. In this work, a FRET system for the detection of OSCS was successfully constructed by using supercharged green fluorescent protein (ScGFP) as the energy donor and dye labelled Hep (Hep-RF1) as the energy acceptor. With heparinase ...
DOI:
10.1039/c7ay01907f

54. Fluorescent sensors for sodium ions

Author:
Gao, Ge; Cao, Yingli; Liu, Wei; Li, Dai; Zhou, Wenhu; Liu, Juewen
Source:
Analytical methods 2017 v.9 no.38 pp. 5570-5579
ISSN:
1759-9679
Subject:
analytical methods; blood; chelating agents; disease diagnosis; fluorescence; fluorescent dyes; hypertension; ions; lithium; nucleic acids; oligonucleotides; potassium; proteins; sodium
Abstract:
... Sodium is a highly important metal in biological systems and its concentration in vivo is tightly regulated. However, the fluctuation of sodium levels is still common and problematic and is responsible for several physiological disorders and illnesses, including hypertension and cardiovascular disease. Analytical methods for measuring sodium in biological samples are of great importance for diseas ...
DOI:
10.1039/c7ay01708a

55. Metal–organic framework enhanced electromembrane extraction – a conceptual study using basic drugs as model substances

Author:
Fakhari, Ali Reza; Asadi, Sajad; Kosalar, Hasan Mohammadi; Sahragard, Ali; Hashemzadeh, Alireza; Amini, Mostafa M.
Source:
Analytical methods 2017 v.9 no.38 pp. 5646-5652
ISSN:
1759-9679
Subject:
analytical methods; coordination compounds; detection limit; methadone; methamphetamines; mixing; models; pH; supported liquid membranes; urine
Abstract:
... This work aims to use an appealing metal–organic framework (MOF), MIL-101(Cr), for the enhancement of electromembrane extraction efficiency. The use of MIL-101(Cr) in the supported liquid membrane (SLM) enhanced the analyte partition coefficient within the membrane, resulting in the enhancement of analyte transport. The optimization of the different variables affecting the proposed method was carr ...
DOI:
10.1039/c7ay01093a

56. Paper test card for detection of adulterated milk

Author:
Luther, Jamie L.; Henry de Frahan, Valentine; Lieberman, Marya
Source:
Analytical methods 2017 v.9 no.38 pp. 5674-5683
ISSN:
1759-9679
Subject:
adulterants; analytical methods; buffers; chemical species; color; developing countries; enzymes; glucose; laboratory experimentation; milk; mobile telephones; nitrogen content; paper; starch; sucrose; urea
Abstract:
... In developing countries, milk is adulterated to meet demand and increase profit. Often the milk is diluted with water, and sugar, urea, and starch are added to mimic the color, consistency, and nitrogen content of the real thing. Since laboratory tests for detecting these adulterants are difficult to perform in a field setting, we developed an inexpensive, paper analytical device (MilkPAD) to dete ...
DOI:
10.1039/c7ay01321c

57. Purification of nitrogen-doped graphene quantum dots via the liquid–liquid extraction system of tetrahydrofuran–(NH₄)₂SO₄–water and its application to sensitive iron(iii) ions determination

Author:
Zhang, Wenjun; Tang, Shaokang; Zhang, Shaopei; Chen, Yi
Source:
Analytical methods 2017 v.9 no.38 pp. 5691-5696
ISSN:
1759-9679
Subject:
ammonium; analytical methods; cutting; fluorescence; graphene; graphene oxide; iron; liquid-liquid extraction; quantitative analysis; quantum dots; rapid methods; wavelengths
Abstract:
... A facile, rapid method based on a liquid–liquid extraction system for the purification of graphene quantum dots is reported in this study. Nitrogen-doped graphene quantum dots (N-GQDs) were synthesized by a simple hydrothermal route for cutting graphene oxide sheets. Then, through the liquid–liquid extraction system of tetrahydrofuran–(NH₄)₂SO₄–water, N-GQDs have been successfully purified. The as ...
DOI:
10.1039/c7ay01841j

58. Quantitative analysis of salvianolic acids, ginsenosides and borneols using ¹H qNMR for quality control of compound Danshen dripping pills

Author:
Chen, Xialin; Qi, Jin; Yu, Boyang
Source:
Analytical methods 2017 v.9 no.38 pp. 5580-5585
ISSN:
1759-9679
Subject:
Oriental traditional medicine; Panax; aldehydes; analytical methods; borneol; danshensu; ginsenosides; quality control; quantitative analysis; rosmarinic acid; salvianolic acid
Abstract:
... Compound Danshen Dripping Pills (CDDPs) are a Chinese herbal medicinal preparation composed of Salviae miltiorrhizae Radix and two other Chinese medicines, Notoginseng Radix and Borneolum. The main components of CDDPs are protocatechuic aldehyde, danshensu, salvianolic acid A, rosmarinic acid, ginsenoside Rg₁, ginsenoside Rb₁, l-(−)-borneol and isoborneol. The complex composition of CDDPs, which c ...
DOI:
10.1039/c7ay00938k

59. Sensitive and selective detection of nitrite ions with highly fluorescent glutathione-stabilized copper nanoclusters

Author:
Zhou, Dan-Ling; Huang, Hong; Wang, Yan
Source:
Analytical methods 2017 v.9 no.38 pp. 5668-5673
ISSN:
1759-9679
Subject:
analytical methods; ascorbic acid; copper; copper nanoparticles; fluorescence; glutathione; ions; nitrites; reducing agents; stabilizers; water solubility
Abstract:
... In this work, we demonstrated a facile green method for the preparation of fluorescent copper nanoclusters (Cu NCs) with a high quantum yield of 8.6%, using glutathione as the stabilizing agent and ascorbic acid as the reductant. The as-prepared Cu NCs had good water solubility and ultrafine sizes. Further investigation revealed that the fluorescence of Cu NCs was linearly quenched by nitrite ions ...
DOI:
10.1039/c7ay02035j

60. A fluorescence-enhanced probe for rapid detection of formaldehyde and its application for cell imaging

Author:
Wu, Feng; Zhang, Yue; Huang, Lei; Xu, Dan; Wang, Hongying
Source:
Analytical methods 2017 v.9 no.37 pp. 5472-5477
ISSN:
1759-9679
Subject:
aldimines; analytical methods; anthracenes; cell membranes; condensation reactions; fluorescence; fluorescent dyes; formaldehyde; image analysis; quantitative analysis; rapid methods; staining; toxicity
Abstract:
... A simple anthracene carboxyimide-based fluorescent probe has been readily developed for the detection of toxic formaldehyde (FA). The probe displays a remarkable fluorescence turn-on response towards FA based on the aldimine condensation reaction, which was confirmed by the HR-MS spectrum. The probe can quantitatively determine the level of FA with high selectivity and fast response (within 3 min) ...
DOI:
10.1039/c7ay01786c

61. A signal-off aptasensor for the determination of Ochratoxin A by differential pulse voltammetry at a modified Au electrode using methylene blue as an electrochemical probe

Author:
Wei, Min; Feng, Shuo
Source:
Analytical methods 2017 v.9 no.37 pp. 5449-5454
ISSN:
1759-9679
Subject:
analytical methods; aptasensors; carbon; complementary DNA; electrochemistry; electrodes; electron transfer; gold; guanine; methylene blue; nanogold; ochratoxin A; oligonucleotides
Abstract:
... In this work, a novel signal-off aptasensor was constructed for the determination of Ochratoxin A (OTA) using differential pulse voltammetry. Methylene blue (MB) was used as an electrochemical indicator by intercalating into a single-stranded aptamer through guanine bases and double-stranded DNA and produced a strong current signal. The prepared carboxylic porous carbon (cPC) and Au nanoparticles ...
DOI:
10.1039/c7ay01735a

62. CoOOH-induced synthesis of fluorescent polydopamine nanoparticles for the detection of ascorbic acid

Author:
Zhao, Yan-Yan; Li, Li; Yu, Ru-Qin; Chen, Ting-Ting; Chu, Xia
Source:
Analytical methods 2017 v.9 no.37 pp. 5518-5524
ISSN:
1759-9679
Subject:
analytical methods; ascorbic acid; cobalt; dopamine; fluorescence; nanoparticles; nanosheets; oxidants; oxidation; quinones
Abstract:
... As an important biological small molecule, ascorbic acid (AA) plays a key role in many bioprocesses. Here, we developed a novel method to evaluate AA based on the redox reaction between CoOOH and AA. In our work, a nanosystem was constructed with fluorescent polydopamine (PDA) nanoparticles and CoOOH nanosheets, which were used as signal indicators and an oxidant respectively. This is the first ti ...
DOI:
10.1039/c7ay01566f

63. Frequency characterization of flow magnitude and phase in resonant microfluidic circuits

Author:
Jain, Rahil; Darling, Robert B.; Lutz, Barry
Source:
Analytical methods 2017 v.9 no.37 pp. 5425-5432
ISSN:
1759-9679
Subject:
analytical methods; electronic circuits; lab-on-a-chip technology; vibration
Abstract:
... The classic electric-hydraulic analogy has been utilized to create microfluidic equivalents of electrical circuits that find applications in lab-on-a-chip and microTAS devices. Despite the continued use of the analogy in pedagogy and for scientific discovery, a thorough experimental validation of this classic analogy using standard electrical characterization techniques has not been performed. In ...
DOI:
10.1039/c7ay01699a

64. GO/Fe₃O₄@SiO₂ core–shell nanocomposite-modified graphite screen-printed electrode for sensitive and selective electrochemical sensing of dopamine and uric acid

Author:
Beitollahi, Hadi; Nejad, Fariba Garkani; Shakeri, Shahryar
Source:
Analytical methods 2017 v.9 no.37 pp. 5541-5549
ISSN:
1759-9679
Subject:
analytical methods; catalytic activity; detection limit; diagnostic techniques; dopamine; electrical conductivity; electrochemistry; electrodes; graphene; silica; surface area; uric acid
Abstract:
... Herein, we report the construction of GO/Fe₃O₄@SiO₂ core–shell nanocomposite-modified graphite screen-printed electrode that shows advantageous characteristics in terms of electrical conductivity, catalytic activity and surface area compared to bare screen-printed electrode. The designed sensor was used for the determination of dopamine and uric acid. Cyclic voltammetry, differential pulse voltamm ...
DOI:
10.1039/c7ay01226h

65. Highly sensitive electrochemical detection of mercuric ions based on sequential nucleic acid amplification and guanine nanowire formation

Author:
Xie, Shunbi; Tang, Ying; Tang, Dianyong
Source:
Analytical methods 2017 v.9 no.37 pp. 5478-5483
ISSN:
1759-9679
Subject:
analytical methods; catalytic activity; disease prevention; electrochemistry; electrodes; environmental protection; gene amplification; guanine; magnesium; mercury; nanowires
Abstract:
... The selective and sensitive detection of mercuric ions (Hg²⁺) is of great significance in environmental protection and disease prevention. By integrating target induced strand displacement amplification (SDA) and metal ion-dependent DNAzyme cyclic amplification to grow guanine nanowires (G-nanowires) as the signal output component, we demonstrate here a label-free and sensitive strategy for Hg²⁺ d ...
DOI:
10.1039/c7ay01916e

66. Analysis of the surface functional groups of organic nanoparticles formed in furfural vapour photonucleation using a rupture event scanning technique

Author:
Dultseva, G. G.; Dubtsov, S. N.; Dultsev, F. N.; Kobzeva, T. V.; Nekrasov, D. V.
Source:
Analytical methods 2017 v.9 no.36 pp. 5348-5355
ISSN:
1759-9679
Subject:
aerosols; analytical methods; free radicals; furfural; moieties; nanoparticles; photochemistry; spectrometers; vapors
Abstract:
... The surface functional groups of organic nanoparticles formed in furfural photonucleation were identified with the help of rupture event scanning. The presence of carboxylic groups on the surface of the particles was discovered. The photonucleation kinetics was studied in a laboratory photochemical reactor using a diffusion-based aerosol spectrometer. It was demonstrated that photonucleation invol ...
DOI:
10.1039/c7ay01437f

67. Biosensing methods for the detection of highly pathogenic avian influenza H5N1 and H7N9 viruses

Author:
Li, Zhanming; Fu, Yingchun; Liao, Ming; Li, Yanbin
Source:
Analytical methods 2017 v.9 no.36 pp. 5238-5248
ISSN:
1759-9679
Subject:
analytical methods; avian influenza; biosensors; host range; immunoassays; molecular biology; monitoring; mutation; pandemic; pathogenicity; point-of-care systems; viruses
Abstract:
... The highly pathogenic avian influenza (HPAI) H5N1 and H7N9 viruses may lead to the next pandemic if human-to-human transmissibility is established because the host range restriction can be changed via virus mutations or reassortments. Therefore, effective and efficient detection methods are crucial for the early stage identification and surveillance of an outbreak of HPAI viruses. In this review, ...
DOI:
10.1039/c7ay01585b

68. Control of pH for separated quantitation of nitrite and cyanide ions using photoluminescent copper nanoclusters

Author:
Cang, Jinshun; Wang, Chia-Wei; Chen, Po-Cheng; Lin, Yi-Jyun; Li, Yu-Chi; Chang, Huan-Tsung
Source:
Analytical methods 2017 v.9 no.36 pp. 5254-5259
ISSN:
1759-9679
Subject:
analytical methods; copper; copper nanoparticles; cyanides; detection limit; ions; lakes; nitrites; pH; photoluminescence; redox reactions; signal-to-noise ratio
Abstract:
... A dual sensing probe has been developed for the detection of nitrite (NO₂⁻) and cyanide (CN⁻) ions based on the analyte-induced photoluminescence (PL) quenching of thiosalicylic acid (TA) capped-copper (Cu) nanocluster (NC) aggregates. The TA–Cu NC aggregates prepared from Cu²⁺ and TA emit at 420 nm when excited at 338 nm, with a quantum yield of 13.2%. The PL quenching of the TA–Cu NC aggregates ...
DOI:
10.1039/c7ay01300k

69. Estimation of relative oxygen metabolic activity microdistribution in biofilms based on the catastrophe point phenomenon during oxygen-infusion processes

Author:
Wang, Jian-Hui; Li, Hai-Yan; Guo, Jin-Song; Yan, Peng; Shen, Yu; Chen, You-Peng
Source:
Analytical methods 2017 v.9 no.36 pp. 5293-5300
ISSN:
1759-9679
Subject:
activated sludge; analytical methods; biochemical pathways; biofilm; dissolved oxygen; erythrocytes; microbial activity; models; oxygen; wastewater treatment
Abstract:
... Biofilm reactors are an alternative technology to the conventional activated sludge process for treating wastewater. Understanding the microbial activity microdistribution in heterogeneous biofilms will enable exploration of microbial microdistribution, substrate transfer, and reaction processes inside biofilms. However, the microbial activity obtained from models and the reported measurement tech ...
DOI:
10.1039/c7ay01773a

70. Fast detection of Escherichia coli in food using nanoprobe and ATP bioluminescence technology

Author:
Zhang, Zhijie; Wang, Chunxing; Zhang, Liren; Meng, Qingtian; Zhang, Yuemin; Sun, Fang; Xu, Yuanda
Source:
Analytical methods 2017 v.9 no.36 pp. 5378-5387
ISSN:
1759-9679
Subject:
Escherichia coli; adenosine triphosphate; analytical methods; antibodies; antigens; bacteria; bioluminescence; detection limit; food safety; magnetism; microbeads; multipliers; nanoparticles; prototypes; signal-to-noise ratio
Abstract:
... In recent years, high demands on food safety technology have made precision and accurate detection technology an urgent research topic. This paper presents a novel biochemical system prototype for colony counting of Escherichia coli using a nano-probe associated with adenosine triphosphate (ATP). The novelty of this system is that the magnetic nanoparticle microbeads are modified with specific ant ...
DOI:
10.1039/c7ay01607g

71. A non-enzymatic ethanol sensor based on a nanostructured catalytic disposable electrode

Author:
Pereira Silva Neves, Marta M.; González-García, M. Begoña; Bobes-Limenes, Pablo; Pérez-Junquera, Alejandro; Hernández-Santos, David; Vidal-Iglesias, Francisco José; Solla-Gullón, José; Fanjul-Bolado, Pablo
Source:
Analytical methods 2017 v.9 no.35 pp. 5108-5114
ISSN:
1759-9679
Subject:
alcoholic beverages; analytical methods; carbon electrodes; catalytic activity; citrates; cost effectiveness; electrochemistry; electron transfer; ethanol; instrumentation; nanoparticles; platinum; scanning electron microscopy; transmission electron microscopy
Abstract:
... Herein, a simple and fast method for the electrocatalytic detection of ethanol using disposable nanostructured screen-printed carbon electrodes (SPCEs) is presented for the first time. Platinum nanoparticles (PtNPs), prepared in the presence of citrate and later purified and dispersed in ultrapure water, were employed in the modification of the SPCEs (SPCE-PtNPs). The synthetized nanoparticles and ...
DOI:
10.1039/c7ay01078h

72. A novel three-dimensional DNA nanostructure used for thrombin detection

Author:
Shu, Huawei; Mei, He; Gu, Jinxin; Yang, Yongbin; Chen, Baoguang; Huang, Ling; Wang, Qun; Chen, Xiaodong; Li, Dong; Gao, Jimin
Source:
Analytical methods 2017 v.9 no.35 pp. 5115-5120
ISSN:
1759-9679
Subject:
analytical methods; aptasensors; blood serum; detection limit; electrochemistry; electrodes; gold; hydrolysis; metal ions; nanosilver; oligonucleotides; single-stranded DNA; thrombin
Abstract:
... In this paper, a label-free electrochemical aptasensor for the detection of thrombin with high sensitivity is proposed. A thrombin-binding capture probe (CP) was designed to form a thrombin/aptamer complex that could reduce the activity of ssDNA DNAzymes, to avoid the hydrolysis of the aptamer monolayers in the presence of thrombin. Furthermore, the presence of the CP enabled auxiliary DNA 1 (AD-1 ...
DOI:
10.1039/c7ay01488k

73. Development of a novel method for the enrichment of unsubstituted naphthalene and phenanthrene from crude oils for compound-specific stable isotope analysis

Author:
Chen, Yongxin; Zhang, Xilong; Chang, Jiang; Ma, Suping; Wu, Yingqin; Xia, Yanqing
Source:
Analytical methods 2017 v.9 no.35 pp. 5135-5139
ISSN:
1759-9679
Subject:
analytical methods; carbon; fractionation; naphthalene; petroleum; phenanthrenes; pyrolysis; stable isotopes
Abstract:
... A novel, effective and easy-to-operate method to enrich unsubstituted naphthalene and phenanthrene directly from crude oils was developed based on closed-system pyrolysis. The pyrolysis at 500 °C for 12 h was found to be sufficient for the enrichment of unsubstituted aromatics that were free of unresolved complex mixture (UCM) and poly-substituted aromatics. This allowed further accurate compound ...
DOI:
10.1039/c7ay01257h

74. Electrochemical enantiorecognition of tryptophan enantiomers based on a multi-walled carbon nanotube–hydroxyethyl chitosan composite film

Author:
Li, Zhenliang; Mo, Zunli; Guo, Ruibin; Meng, Shujuan; Wang, Ruijuan; Gao, Huhu; Niu, Xiaohui
Source:
Analytical methods 2017 v.9 no.35 pp. 5149-5155
ISSN:
1759-9679
Subject:
analytical methods; carbon; carbon nanotubes; chitosan; composite films; composite materials; electrochemistry; enantiomers; enantioselectivity; hydrogen bonding; moieties; sensors (equipment); tryptophan
Abstract:
... A novel chiral electrochemical sensor based on hydroxyethyl chitosan (HECS) covalently binding with the carboxylic multi-walled carbon nanotubes (MWCNT–COOH) was fabricated for discrimination of tryptophan (Trp) enantiomers. HECS preferably combined with l-Trp than with d-Trp because of the favorability of host–guest interactions between HECS and Trp enantiomers. Thus, the recognition efficiency w ...
DOI:
10.1039/c7ay01775h

75. Rapid and sensitive detection of E. coli O157:H7 based on antimicrobial peptide functionalized magnetic nanoparticles and urease-catalyzed signal amplification

Author:
Qiao, Zhaohui; Lei, Chunyang; Fu, Yingchun; Li, Yanbin
Source:
Analytical methods 2017 v.9 no.35 pp. 5204-5210
ISSN:
1759-9679
Subject:
Escherichia coli O157; ammonium; analytical methods; antimicrobial peptides; apple juice; bacteria; binding sites; bioassays; color; detection limit; electrostatic interactions; food pathogens; foodborne illness; ground beef; hydrolysis; hydrophobic bonding; magnetic separation; magnetism; nanoparticles; pH; urea; urease
Abstract:
... The development of rapid and sensitive detection of foodborne pathogens could effectively prevent or reduce the outbreaks of foodborne diseases. Herein, a simple, rapid, and sensitive detection of E. coli O157:H7 was developed based on antimicrobial peptide functionalized magnetic nanoparticles (MNP–AMP) and urease-catalyzed signal amplification. In this study, MNP–AMP were fabricated to capture E ...
DOI:
10.1039/c7ay01643c

76. Spiegelmers as potential receptors for cTnI diagnostics

Author:
Szeitner, Zsuzsanna; Doleschall, Anna; Varga, Marina; Keltai, Katalin; Révész, Katalin; Gyurcsányi, Róbert E.; Mészáros, Tamás
Source:
Analytical methods 2017 v.9 no.35 pp. 5091-5093
ISSN:
1759-9679
Subject:
analytical methods; blood serum; diagnostic techniques; enzymes; luminescence; oligonucleotides; receptors; troponin I
Abstract:
... We demonstrate the first application of a nuclease resistant aptamer, the so-called Spiegelmer, in a sandwich-type affinity assay by quantitative assessment of cardiac Troponin I (cTnI) in blood serum samples. To this end, we used a bead-based homogenous proximity assay (AlphaLISA) in which luminescence is generated by the Spiegelmer and antibody-modified donor and acceptor beads brought into prox ...
DOI:
10.1039/c7ay01777d

77. A coaxial extractive electrospray ionization source

Author:
Swanson, Kenneth. D.; Worth, Anne. L.; Glish, Gary. L.
Source:
Analytical methods 2017 v.9 no.34 pp. 4997-5002
ISSN:
1759-9679
Subject:
analytical methods; atomization; ionization; solvents; standard deviation
Abstract:
... An extractive electrospray ionization (EESI) source design is presented to improve the reproducibility of the interactions occurring in EESI. This design uses three concentric capillaries to deliver the solvent, sample and nebulizing gas. Coaxial EESI was found to improve the inter-experiment variation by a factor of four and intra-run relative standard deviation by a factor of 2.4. Unlike most st ...
DOI:
10.1039/c7ay00835j

78. Forensic discrimination between authentic and counterfeit perfumes using paper spray mass spectrometry and multivariate supervised classification

Author:
Teodoro, J. A. R.; Pereira, H. V.; Correia, D. N.; Sena, M. M.; Piccin, E.; Augusti, R.
Source:
Analytical methods 2017 v.9 no.34 pp. 4979-4987
ISSN:
1759-9679
Subject:
allergenicity; analytical methods; cosmetics; discriminant analysis; forensic sciences; ionization; ions; least squares; models; perfumes; prediction; principal component analysis; rapid methods
Abstract:
... Perfumes are cosmetic products with high added value and worldwide consumption, which make them a potential target for counterfeiting. A novel, simple and rapid method was developed for the differentiation of samples of authentic and counterfeit perfumes by employing paper spray mass spectrometry (PS-MS) combined with multivariate supervised classification models: Partial Least Squares Discriminan ...
DOI:
10.1039/c7ay01295k

79. Pulsed probe electrospray and nano-electrospray: the temporal profiles of ion formation from the Taylor cone

Author:
Usmanov, Dilshadbek T.; Hiraoka, Kenzo; Ninomiya, Satoshi; Chen, Lee Chuin; Wada, Hiroshi; Matsumura, Masaya; Sanada-Morimura, Sachiyo; Nakata, Keisuke; Nonami, Hiroshi
Source:
Analytical methods 2017 v.9 no.34 pp. 4958-4963
ISSN:
1759-9679
Subject:
acetic acid; ammonium acetate; analytical methods; cytochrome c; eggs; electric potential difference; ionization; ketchup; mayonnaise; natto; salmon; silica; soybeans; tomatoes
Abstract:
... The temporal profiles of ion signals were measured for probe electrospray ionization (PESI) and nano-electrospray ionization (nESI) by changing the pulse width of the high voltage applied to the emitters (PESI: 0.12 mm o.d. and 700 nm tip diameter metal needle; nESI: metal-coated 15 μm i.d. silica capillary). The ion signals started to be detected at ∼400 μs and 5 ms, respectively, for PESI and nE ...
DOI:
10.1039/c7ay01275f

80. Secondary electrospray ionization proceeds via gas-phase chemical ionization

Author:
Rioseras, Alberto Tejero; Gaugg, Martin Thomas; Martinez-Lozano Sinues, Pablo
Source:
Analytical methods 2017 v.9 no.34 pp. 5052-5057
ISSN:
1759-9679
Subject:
analytical methods; droplets; ionization; solvents; vapors
Abstract:
... Our main goal was to gain further insights into the mechanism by which gas-phase analytes are ionized by interaction with plumes of electrospray solvents. We exposed target vapors to electrosprays of either water or deuterated water and mass analyzed them. Regardless of the solvent used, the analytes were detected in protonated form. In contrast, when the ionization chamber was humidified with deu ...
DOI:
10.1039/c7ay01121k

81. A fluorescent aptasensor with product-triggered amplification by exonuclease III digestion for highly sensitive ATP detection

Author:
He, Shengnan; Qu, Long; Tan, Ying; Liu, Feng; Wang, Yu; Zhang, Wei; Cai, Zhiming; Mou, Lisha; Jiang, Yuyang
Source:
Analytical methods 2017 v.9 no.33 pp. 4837-4842
ISSN:
1759-9679
Subject:
DNA probes; adenosine triphosphate; analytical methods; aptasensors; binding capacity; detection limit; enzymatic hydrolysis; fluorescence; graphene oxide; nucleases; oligonucleotides
Abstract:
... Here we proposed a conceptually new amplified ATP assay by combination of exonuclease III (Exo III) with an allosteric aptasensor triggered by ATP with graphene oxide (GO) assistance. The assay needs only one single fluorophore-labelled DNA probe, which was designed having the fluorescence labelled nucleotide and enzymatic substrate sequence away from the ATP recognition aptamer sequence to avoid ...
DOI:
10.1039/c7ay01473b

82. A novel storage and extraction method using solid-phase adsorption and ultrasonic-assisted nebulization extraction coupled to solid phase extraction

Author:
Zhang, Peixu; Li, Xuwen; Cui, Li; Chen, Jiafeng; Qu, Yan; Wang, Xiaozhong; Wu, Qian; Liu, Ying; Zhou, Chunkui; Jin, Yongri
Source:
Analytical methods 2017 v.9 no.33 pp. 4863-4872
ISSN:
1759-9679
Subject:
adsorbents; adsorption; ambient temperature; analytical methods; atomization; diatomaceous earth; ginsenosides; models; pH; solid phase extraction; storage quality; storage time; zinc sulfate
Abstract:
... A novel storage and extraction method was developed for biofluids. Plasma spiked with four types of minor ginsenosides (Rg₂, Rg₃, Rh₁ and Rh₂) was used as a model biofluid to evaluate this method. The method was based on solid-phase adsorption and ultrasonic-assisted nebulization coupled with solid phase extraction (SPA-UANE-SPE). Diatomaceous earth was used as an adsorbent to store the plasma for ...
DOI:
10.1039/c7ay01036b

83. New luminescent nanoparticles based on carbon dots/SiO₂ for the detection of latent fingermarks

Author:
Zhao, Ya-Bin; Ma, Yu-jie; Song, Dan; Liu, Yun; Luo, Yaping; Lin, Sheng; Liu, Chun-yan
Source:
Analytical methods 2017 v.9 no.33 pp. 4770-4775
ISSN:
1759-9679
Subject:
aluminum foil; analytical methods; carbon quantum dots; drugs; fluorescence; glass; leather; microparticles; plastic bags; porous media; powders; silica; wavelengths
Abstract:
... This article explores the application of a newly developed non-toxic mesoporous hybrid of carbon dot silica microspheres (CDs/SiO₂) in the detection of latent fingermarks. The CDs/SiO₂ was synthesized from silane-functionalised carbon dots (Si-CDs) and tetraethyl orthosilicate (TEOS) as precursors. The nanoparticles had a spherical morphology with an average diameter of 141 nm, which was advantage ...
DOI:
10.1039/c7ay01316g

84. Preparation of polyacrylic acid surface-crosslinked strong fluorescent polymer nanoparticles and their sensitive in vitro imaging of cancer cells and long-life in vivo imaging of in situ tumors

Author:
Cai, Xue-Ping; He, Huan-Huan; Ding, Hai-Yang; Chen, Xiao-Bo; Wei, Tong-Hong; Song, Tian-mei; You, Si-Jia; Xie, Hong-Ping; Min, Chun-Yan
Source:
Analytical methods 2017 v.9 no.33 pp. 4797-4807
ISSN:
1759-9679
Subject:
analytical methods; crosslinking; enzymatic hydrolysis; fluorescein; fluorescence; hydrophilicity; hydrophobic bonding; hydrophobicity; image analysis; ligands; nanoparticles; neoplasm cells; neoplasms; oligonucleotides; particle size; polyacrylic acid
Abstract:
... Fluorescent nanoparticles with a novel structure suitable for detecting cancer cells in vitro and in vivo have been prepared. Firstly, a strong, hydrophilic, branched amino polymer was synthesized, and then it was chemically conjugated as much as possible with fluorescein (FAM) to further synthesize a hydrophobic FAM-branched polymer with strong fluorescence. Fluorescein polymer nanoparticles (FPN ...
DOI:
10.1039/c7ay01392b

85. A new fluorescence chemosensor for Zn²⁺ with a remarkable red shift in emission spectra

Author:
Azadbakht, Reza; Koolivand, Mostafa; Khanabadi, Javad
Source:
Analytical methods 2017 v.9 no.32 pp. 4688-4694
ISSN:
1759-9679
Subject:
analytical methods; detection limit; fluorescence; ions; naphthalene; zinc
Abstract:
... A new fluorescent chemosensor with a remarkable red shift in emission spectra based on naphthalene groups for quantification of zinc ions was synthesized and investigated. It was found that sensor H₂L exhibited a remarkably large red shift in emission upon complexation with Zn²⁺ ions. The limit of detection (LOD) was calculated to be 4.98 × 10⁻⁹ M. The fluorescence behavior of the prepared compoun ...
DOI:
10.1039/c7ay01568b

86. Facile fabrication of an “off–on” photoelectrochemical aptasensor for kanamycin detection based on polypyrrole/CeO₂

Author:
Lv, Jiaxin; Lei, Qin; Xiao, Qiyou; Li, Xiaomin; Huang, Yujie; Li, He
Source:
Analytical methods 2017 v.9 no.32 pp. 4754-4759
ISSN:
1759-9679
Subject:
analytical methods; aptasensors; ceric oxide; kanamycin; milk; nanogold; oligonucleotides; pyrroles
Abstract:
... In this work, an “off–on” photoelectrochemical sensing strategy for the determination of trace kanamycin is proposed by using a kanamycin aptamer as the sensing unit, gold nanoparticles (AuNPs) and polypyrrole as the signal amplification unit and cerium dioxide as the photoelectric active material. The proposed method has a good linear range from 0.5–200 μg L⁻¹ with a detection limit of 0.2 μg L⁻¹ ...
DOI:
10.1039/c7ay01611e

87. Optimization of subcritical water extraction of phenolic antioxidants from pomegranate (Punica granatum L.) peel by response surface methodology

Author:
Yan, Linlin; Cao, Yungang; Zheng, Guangyao
Source:
Analytical methods 2017 v.9 no.32 pp. 4647-4656
ISSN:
1759-9679
Subject:
2,2-diphenyl-1-picrylhydrazyl; Punica granatum; analytical methods; antioxidant activity; antioxidants; ellagic acid; experimental design; flavonoids; pomegranates; response surface methodology; temperature
Abstract:
... Subcritical water extraction (SWE), a ‘green’ and efficient extraction technology, was applied to extract phenolic antioxidants from pomegranate peel in this study. In single-factor experiments, the effects of extraction temperature (100–220 °C), time (5–80 min) and the water/solid ratio (20–60 mL g⁻¹) on the extraction yields of total phenolics (TP), total flavonoids (TF), and major phenolic comp ...
DOI:
10.1039/c7ay01475a

88. Research on a beef tenderness detection method using a bionic mastication system based on a pressure sensor

Author:
Wang, Xiaodan; Wang, Hongmei; Cai, Yingming; Jin, Jiahui; Zhu, Lingtao; Xu, Liping
Source:
Analytical methods 2017 v.9 no.32 pp. 4695-4701
ISSN:
1759-9679
Subject:
analytical methods; beef; chicken meat; chickens; electric potential difference; longissimus muscle; mastication; pork; prices; sensory evaluation; shear stress; strain gauges
Abstract:
... Beef tenderness is a significant factor which influences consumer purchase opinion. Conventional assessment of tenderness requires lengthy procedures with tedious sample preparations. An objective and rapid bionic mastication system combined with a pressure sensor and strain gauge for assessing beef tenderness was developed in this study. Samples of the mid-region of each longissimus dorsi (LD) we ...
DOI:
10.1039/c7ay00802c

89. Square-wave adsorptive anodic stripping voltammetric determination of ramipril using an electrochemical sensor based on nanostructured carbon black

Author:
Silva, Tiago Almeida; Fatibello-Filho, Orlando
Source:
Analytical methods 2017 v.9 no.32 pp. 4680-4687
ISSN:
1759-9679
Subject:
analytical methods; coatings; detection limit; drugs; electrochemistry; electrons; glassy carbon electrode; oxidation; sensors (equipment); soot
Abstract:
... A novel and alternative electroanalytical method for the determination of ramipril (RAM) using a glassy carbon electrode (GCE) modified with nanostructured carbon black (CB) is reported. The electrochemical sensor was obtained by a simple drop coating strategy, and the designed architecture consisted of a GCE modified with CB within a dihexadecylphosphate film. The remarkable electrocatalytic acti ...
DOI:
10.1039/c7ay01479a

90. An electrochemical aptasensor for detection of bovine interferon gamma

Author:
Crulhas, Bruno P.; Hadley, Dustin; Liu, Ying; Shin, Dong-Sik; Stybayeva, Gulnaz; Imanbekova, Meruyert; Hill, Ashley E.; Pedrosa, Valber; Revzin, Alexander
Source:
Analytical methods 2017 v.9 no.31 pp. 4527-4532
ISSN:
1759-9679
Subject:
Mycobacterium tuberculosis; T-lymphocytes; analytical methods; aptasensors; bovine tuberculosis; cattle; electrochemistry; electrodes; electron transfer; gold; interferon-gamma; methylene blue; oligonucleotides
Abstract:
... Bovine tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) in which it is hard to identify the pathological symptoms. Release of bovine interferon gamma (BoIFN-γ) by T-cells provides an important diagnostic marker of MTB infections. In this work, we developed for the first time an electrochemical aptasensor for sensitive and specific determination of BoIFN-γ. A th ...
DOI:
10.1039/c7ay01313b

91. A novel two-photon fluorescent probe for the selective detection of hydrogen peroxide based on a naphthalene derivative

Author:
Ma, Qiujuan; li, Xian; Zhang, Jing; Zhu, Xiaoyan; Zhou, Liyi; Liu, Hongwen
Source:
Analytical methods 2017 v.9 no.31 pp. 4558-4565
ISSN:
1759-9679
Subject:
analytical methods; boric acid; fluorescence; fluorescent dyes; hydrogen peroxide; image analysis; microscopy; monitoring; naphthalene
Abstract:
... In this study, we report a novel two-photon fluorescent probe for monitoring hydrogen peroxide. Probe 1 consists of a naphthalene backbone and a boric acid ester which was used as a H₂O₂ reporter. The reaction of probe 1 with H₂O₂ triggers the cleavage of a boronate-based protecting group, and as a result, restores the fluorescence of compound 2. The probe can be applied to the quantification of h ...
DOI:
10.1039/c7ay01249g

92. Efficient removal and trace determination of chlorophenols from water using mixed hemi-/ad-micelle ionic liquid-coated magnetic graphene oxide and the adsorption mechanism

Author:
Liu, Wei; Zha, Jun; Meng, Xiaoyan; Wu, Jianrong; Sun, Cheng; Qiu, Panzi; Fizir, Meriem; He, Hua
Source:
Analytical methods 2017 v.9 no.31 pp. 4581-4591
ISSN:
1759-9679
Subject:
adsorbents; adsorption; analytical methods; chemical species; computer simulation; detection limit; graphene oxide; iron oxides; magnetism; nanoparticles; response surface methodology; solid phase extraction; surface area; tap water; zeta potential
Abstract:
... Mixed hemi-micelle magnetic solid phase extraction (MHMSPE) based on magnetic graphene oxide nanoparticles (MGONPs) and 1-hexadecyl-3-methylimidazolium bromide (C₁₆mimBr) was developed for the efficient removal and trace determination of chlorophenols (CPs) in water. The adsorption mechanism of three kinds of CP was studied by applying computer simulation and zeta-potential studies. The large surf ...
DOI:
10.1039/c7ay01241a

93. Methods to coalesce fluorinated Pickering emulsions

Author:
Pan, Ming; Lyu, Fengjiao; Tang, Sindy K. Y.
Source:
Analytical methods 2017 v.9 no.31 pp. 4622-4629
ISSN:
1759-9679
Subject:
additives; analytical methods; centrifugation; droplets; electric field; emulsions; energy; microfluidic technology; nanoparticles; polyethylene glycol; surfactants; surveys
Abstract:
... This work surveys methods to coalesce water-in-fluorocarbon emulsions stabilized by amphiphilic nanoparticles (NPs) for applications in droplet microfluidics. Most droplet assays to date have relied on one type of surfactant consisting of perfluorinated polyether and polyethylene glycol (PFPE–PEG) to stabilize the drops against coalescence. Nonetheless, this surfactant is known to have several lim ...
DOI:
10.1039/c7ay01289f

94. Preparation of carbon nanodots capped by polyethylene glycol as a multifunctional sensor for temperature and paracetamol

Author:
Qu, Fei; Xue, Fangfang; Liu, Jing; You, Jinmao
Source:
Analytical methods 2017 v.9 no.31 pp. 4533-4538
ISSN:
1759-9679
Subject:
acetaminophen; ambient temperature; analytical methods; ascorbic acid; blood serum; carbon; chelates; fluorescence; hot water treatment; humans; iron; molecular weight; nanotechnology; photosynthetically active radiation; polyethylene glycol; thermosensitivity; transmittance; urine
Abstract:
... In this paper, a simple and green preparative strategy for synthesizing carbon nanodots (CNDs) is developed by a one-pot hydrothermal method, using ascorbic acid (AA) as the carbon source and polyethylene glycol (PEG) with a molecular weight of 1500 as the surface modification agent. Through changing the amount ratio of PEG-1500 to AA in the synthesis, we can obtain PEG-CNDs with different functio ...
DOI:
10.1039/c7ay01180f

95. Versatility of a carbon paste electrode coupled to differential pulse voltammetry for determination of lisinopril with its associations (hydrochlorothiazide and amlodipine)

Author:
Valezi, Camila Farinha; Pires Eisele, Ana Paula; Romão Sartori, Elen
Source:
Analytical methods 2017 v.9 no.31 pp. 4599-4608
ISSN:
1759-9679
Subject:
analytical methods; antihypertensive agents; calcium channel blockers; carbon electrodes; detection limit; drug formulations; electrolytes; hydrochlorothiazide; hypertension; pH; potassium chloride; silver; silver chloride; tap water; viability
Abstract:
... Lisinopril (LNP) is an angiotensin converting enzyme inhibitor formulated with a diuretic, hydrochlorothiazide (HCTZ), or with a calcium channel blocker, amlodipine (AML), in a single tablet for treatment of hypertension. In this work, for the first time, two analytical methods are proposed for the determination of pairs of antihypertensives (HCTZ and LNP or AML and LNP). Both methods are based on ...
DOI:
10.1039/c7ay01455d

96. A label-free fluorescence nanosensor for the determination of adrenaline based on graphene quantum dots

Author:
Wang, Mengke; Li, Yan; Wang, Lei; Su, Xingguang
Source:
Analytical methods 2017 v.9 no.30 pp. 4434-4438
ISSN:
1759-9679
Subject:
analytical methods; biosensors; blood serum; epinephrine; fluorescence; graphene; humans; quantum dots
Abstract:
... In this paper, graphene quantum dots (GQDs) were employed to design an effective and simple fluorescence biosensor for the detection of adrenaline (AD). AD could quench the fluorescence of GQDs on account of photoinduced charge transfer (PCT) by the noncovalent interaction with GQDs. Hence, the concentration of AD could be effectively monitored according to the variation of the fluorescence signal ...
DOI:
10.1039/c7ay01271c

97. A ZnO–RGO-modified electrode coupled to microwave digestion for the determination of trace cadmium and lead in six species fish

Author:
Zhang, Wen; Xu, Yiwei; Zou, Xiaobo
Source:
Analytical methods 2017 v.9 no.30 pp. 4418-4424
ISSN:
1759-9679
Subject:
analytical methods; cadmium; electrodes; fish; graphene oxide; lead; microwave treatment; nanoparticles; scanning electron microscopy; zinc oxide
Abstract:
... Herein, a composite of a ZnO nanoparticle and reduced graphene oxide (RGO) was employed as a sensing interface in a practical electrode for the determination of cadmium (Cd²⁺) and lead (Pb²⁺). A suspension comprising the ZnO nanoparticle and RGO was synthesized via the wet-chemical method. The ZnO–RGO-modified electrode was obtained by drop-coating the prepared suspension onto a screen-printed ele ...
DOI:
10.1039/c7ay01574g

98. Fabrication of a TiO₂ and clay nanoparticle composite electrode as a sensor

Author:
Bukkitgar, S. D.; Shetti, N. P.
Source:
Analytical methods 2017 v.9 no.30 pp. 4387-4393
ISSN:
1759-9679
Subject:
analytical methods; atorvastatin; carbon electrodes; clay; clinical trials; detection limit; diffusivity; electrochemistry; humans; nanoclays; nanoparticles; oxidation; reaction mechanisms; titanium dioxide; urine
Abstract:
... In the present study, a simple, selective, and sensitive electrochemical method for the determination of atorvastatin was proposed based on a composite electrode. The electrode was prepared using nanoclay and a carbon paste electrode, to which TiO₂ nanoparticles were added to investigate the electrode behaviour towards atorvastatin detection. Cyclic voltammetric technique was used to investigate t ...
DOI:
10.1039/c7ay01068k

99. The seeded-synthesis of core–shell Au dumbbells with inbuilt Raman molecules and their SERS performance

Author:
Jiang, Tao; Wang, Xiaolong; Tang, Jing; Zhou, Jun; Gu, Chenjie; Tang, Shiwei
Source:
Analytical methods 2017 v.9 no.30 pp. 4394-4399
ISSN:
1759-9679
Subject:
analytical methods; encapsulation; gold; nanogold; nanoparticles; nanorods; pollutants; standard deviation
Abstract:
... Core-shell Au dumbbells with inbuilt Raman molecules were synthesized by a seeded reduction method using core–shell Au nanorod (NR)@PSPAA nanoparticles as the seed. Most of the NRs finally maintained two secondary growth caps on the ends, showing a dumbbell-like shape. The lengths of the NRs were from 350 to 450 nm and the diameters of the caps were about 95 ± 20 nm. Due to the existence of “hot s ...
DOI:
10.1039/c7ay01449j

100. dPCR – the digital polymerase chain reaction

Author:
Analytical Methods Committee AMCTB No. 79,
Source:
Analytical methods 2017 v.9 no.29 pp. 4225-4227
ISSN:
1759-9679
Subject:
DNA; analytical methods; quantitative polymerase chain reaction; uncertainty
Abstract:
... Quantitative real-time PCR (qPCR) is based on the assumption that the amplification of DNA target molecules is exponential. DNA targets may be quantified by comparing the number of amplification cycles required to achieve a predetermined signal threshold to that obtained for a calibrant. However, many factors complicate this calculation, creating uncertainties and inaccuracies. Digital PCR (dPCR) ...
DOI:
10.1039/c7ay90093g