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- Yang, Feng-Qing, et al. Show all 6 Authors
- Analytical methods 2017 v.9 no.35 pp. 5174-5180
- affinity chromatography; chlorogenic acid; coagulation; computer simulation; dissociation; ferulic acid; gallic acid; protocatechuic acid; sinapic acid; thrombin
- ... As a serine protease, thrombin (THR) plays an important role in the coagulation cascade. In this study, a frontal affinity chromatography (FAC) method was developed for the characterization of interactions between immobilized thrombin and phenolic acids, which have potential thrombin inhibitory activity. First, a simple method to immobilize thrombin was developed, where an immobilized artificial m ...