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- Shen, Yu-Dong; Xiao, Ben; Xu, Zhen-Lin; Lei, Hong-Tao; Wang, Hong; Yang, Jin-Yi; Sun, Yuan-Ming
- Analytical methods 2011 v.3 no.12 pp. 2797-2803
- European Union; bovine serum albumin; chickens; chlorpromazine; cross reaction; detection limit; enzyme-linked immunosorbent assay; haptens; high performance liquid chromatography; inhibitory concentration 50; liver; monitoring; ovalbumin; polyclonal antibodies; pork; regression analysis; sedatives; swine
- ... The use of chlorpromazine (CPZ) as a sedative for livestock has been prohibited in the European Union and many other countries. In this study, a new hapten 7-amino-chlorpromazine sulfoxide (hapten 1) against CPZ was synthesized and coupled to ovalbumin (OVA) as an immunogen to produce polyclonal antibody (PAb) specific for CPZ. An heterologous hapten 7-(4-carboxyl-phenylazo)-chlorpromazine (hapten ...