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- Lin, L.; Flisikowski, K.; Schwarzenbacher, H.; Scharfe, M.; Severitt, S.; Blöcker, H.; Fries, R.
- Animal genetics 2010 v.41 no.2 pp. 203-207
- muscle development; haplotypes; glucose; German Landrace; genotyping; homeostasis; introns; radiation hybrid mapping; sequence analysis; energy; protein subunits; muscles; lipid metabolism; exons; single nucleotide polymorphism; swine; AMP-activated protein kinase; protein synthesis; bacterial artificial chromosomes; amino acid substitution
- ... AMP-activated protein kinase (AMPK), known as a key regulator of cellular energy homeostasis, plays an important role in regulation of glucose and lipid metabolism, and protein synthesis in mammals. The characterization of porcine PRKAA2 encoding the alpha 2 catalytic subunit of AMPK is reported in this study. PRKAA2 was assigned to porcine chromosome 6q by analysis of radiation hybrids (IMpRH pan ...
- Xie, S.S.; Huang, T.H.; Shen, Y.; Li, X.Y.; Zhang, X.X.; Zhu, M.J.; Qin, H.Y.; Zhao, S.H.
- Animal genetics 2010 v.41 no.2 pp. 179-190
- gene expression; genome; humans; liver; mice; microRNA; muscle development; muscles; non-coding RNA; quantitative polymerase chain reaction; sequence analysis; skeletal muscle; swine
- ... MicroRNAs (miRNAs) are a class of non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. There is increasing evidence to suggest that miRNAs participate in muscle development in mice and humans; however, few studies have focused on miRNAs in porcine muscle tissue. Here, we experimentally detected and identified conserved and unique miRNAs from porcine skeletal ...