PubAg

Main content area

Search

11  Search Results

1 - 11 of 11
Number of results to display per page

Search Results

1. Genome‐wide association study reveals candidate genes associated with body measurement traits in Chinese Wagyu beef cattle

Author:
An, B.; Xia, J.; Chang, T.; Wang, X.; Xu, L.; Zhang, L.; Gao, X.; Chen, Y.; Li, J.; Gao, H.
Source:
Animal genetics 2019 v.50 no.4 pp. 386-390
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; beef cattle; body length; genes; genetic improvement; genome-wide association study; hips; single nucleotide polymorphism; single nucleotide polymorphism arrays;     Show all 9 Subjects
Abstract:
... We performed a genome‐wide association study to identify candidate genes for body measurement traits in 463 Wagyu beef cattle typed with the Illumina Bovine HD 770K SNP array. At the genome‐wide level, we detected 18, five and one SNPs associated with hip height, body height and body length respectively. In total, these SNPs are within or near 11 genes, six of which (PENK, XKR4, IMPAD1, PLAG1, CCN ...
DOI:
10.1111/age.12805

2. Association of the expression levels in the skeletal muscle and a SNP in the CDC10 gene with growth‐related traits in Japanese Black beef cattle

Author:
Tong, B.; Li, G. P.; Sasaki, S.; Muramatsu, Y.; Ohta, T.; Kose, H.; Yamada, T.
Source:
Animal genetics 2015 v.46 no.2 pp. 200-204
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; Brown Swiss; beef; beef cattle; cell proliferation; dairy cattle; genes; genetic variation; growth performance; marbling; marker-assisted selection; promoter regions; quantitative polymerase chain reaction; quantitative trait loci; single nucleotide polymorphism; skeletal muscle; steers; Japan;     Show all 18 Subjects
Abstract:
... Growth performance, as well as marbling, is the main breeding objective in Japanese Black (JB) cattle, the major beef breed in Japan. The septin 7 (CDC10) gene, involved in cellular proliferation, is located within a genomic region of a quantitative trait locus for growth‐related traits. In this study, we first showed that the expression levels of the CDC10 gene in the skeletal muscle were higher ...
DOI:
10.1111/age.12274

3. Identification of an FBN1 mutation in bovine Marfan syndrome‐like disease

Author:
Hirano, T.; Matsuhashi, T.; Kobayashi, N.; Watanabe, T.; Sugimoto, Y.
Source:
Animal genetics 2012 v.43 no.1 pp. 11-17
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; body weight; cattle; face; genes; humans; messenger RNA; microsatellite repeats; mutation; phenotype; progeny; spermatozoa; stop codon; withers;     Show all 14 Subjects
Abstract:
... Mutations in the gene encoding fibrillin‐1 (FBN1), a component of the extracellular microfibril, cause Marfan syndrome (MFS). Frequent observation of cattle with a normal withers height, but lower body weight than age‐matched normal cattle, was recently reported among cattle sired by phenotypically normal Bull A, in Japanese Black cattle. These cattle also showed other characteristic features simi ...
DOI:
10.1111/j.1365-2052.2011.02209.x
PubMed:
22221020

4. Differentially expressed genes during bovine intramuscular adipocyte differentiation profiled by serial analysis of gene expression

Author:
Mizoguchi, Y.; Hirano, T.; Itoh, T.; Aso, H.; Takasuga, A.; Sugimoto, Y.; Watanabe, T.
Source:
Animal genetics 2010 v.41 no.4 pp. 436-441
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; beef; cattle; gene expression; gene expression regulation; genes; intramuscular fat; lipogenesis; marbling; quantitative trait loci;     Show all 10 Subjects
Abstract:
... Beef marbling or intramuscular fat deposition is an economically important carcass trait in Japanese Black cattle. To investigate genes involved in intramuscular adipogenesis, differential gene expression during adipogenesis in a clonal bovine intramuscular preadipocyte (BIP) cell line was profiled with serial analysis of gene expression (SAGE). We sequenced 75 283 tags for the proliferation phase ...
DOI:
10.1111/j.1365-2052.2010.02022.x
PubMed:
20219066

5. The SNP c.1326T>G in the non‐SMC condensin I complex, subunit G (NCAPG) gene encoding a p.Ile442Met variant is associated with an increase in body frame size at puberty in cattle

Author:
Setoguchi, K.; Watanabe, T.; Weikard, R.; Albrecht, E.; Kühn, C.; Kinoshita, A.; Sugimoto, Y.; Takasuga, A.
Source:
Animal genetics 2011 v.42 no.6 pp. 650-655
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; Charolais; Holstein; adolescence; bulls; carcass weight; genes; humans; loci; puberty; quantitative trait loci; single nucleotide polymorphism; steers;     Show all 13 Subjects
Abstract:
... Recently, we had located a bovine carcass weight QTL, CW‐2, to a 591‐kb interval on BTA6 and have identified the SNP c.1326T>G in the NCAPG (non‐SMC condensin I complex, subunit G) gene that leads to the amino acid change p.Ile442Met in the NCAPG protein, which is a candidate causative variation. Here, we examined the association of the NCAPG:c.1326T>G locus with linear skeletal measurements of gr ...
DOI:
10.1111/j.1365-2052.2011.02196.x
PubMed:
22035007

6. A missense mutation (p.Leu2153His) of the factor VIII gene causes cattle haemophilia A

Author:
Khalaj, M.; Abbasi, A.R.; Shimojo, K.; Moritomo, Y.; Yoneda, K.; Kunieda, T.
Source:
Animal genetics 2009 v.40 no.5 pp. 763-765
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; amino acid substitution; cattle; factor VIII; genes; genotyping; hemophilia; hemorrhage; histidine; leucine; missense mutation; pedigree;     Show all 12 Subjects
Abstract:
... Two cases of hereditary bleeding disorder diagnosed as haemophilia A were recently observed in Japanese Brown cattle. We sequenced the entire coding region of the factor VIII gene of the affected animals to find a causative mutation. A nucleotide substitution of T to A resulting in an amino acid substitution of leucine to histidine (p.Leu2153His) was identified in a highly conserved residue in the ...
DOI:
10.1111/j.1365-2052.2009.01906.x
PubMed:
19456318

7. Linkage mapping of the locus responsible for forelimb-girdle muscular anomaly of Japanese black cattle on bovine chromosome 26

Author:
Masoudi, A.A.; Uchida, K.; Yokouchi, K.; Ohwada, K.; Abbasi, A.R.; Tsuji, T.; Watanabe, T.; Hirano, T.; Sugimoto, Y.; Kunieda, T.
Source:
Animal genetics 2008 v.39 no.1 pp. 46-50
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; calves; chromosome mapping; genes; haplotypes; herds; loci; microsatellite repeats; muscle fibers; muscles; pedigree; shoulders; sires;     Show all 13 Subjects
Abstract:
... Forelimb-girdle muscular anomaly is an autosomal recessive disorder of Japanese black cattle characterized by tremor, astasia and abnormal shape of the shoulders. Pathological examination of affected animals reveals hypoplasia of forelimb-girdle muscles with reduced diameter of muscle fibres. To identify the gene responsible for this disorder, we performed linkage mapping of the disorder locus usi ...
DOI:
10.1111/j.1365-2052.2007.01679.x
PubMed:
18254734

8. Whole-genome association study for fatty acid composition of oleic acid in Japanese Black cattle

Author:
Uemoto, Y.; Abe, T.; Tameoka, N.; Hasebe, H.; Inoue, K.; Nakajima, H.; Shoji, N.; Kobayashi, M.; Kobayashi, E.
Source:
Animal genetics 2011 v.42 no.2 pp. 141-148
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; cattle; fatty acid composition; fatty-acid synthase; genes; genotyping; intramuscular fat; loci; meat quality; models; muscles; oleic acid; phenotype; single nucleotide polymorphism; stearoyl-CoA desaturase;     Show all 15 Subjects
Abstract:
... Fatty acid composition, especially oleic acid (C18:1), plays an important role in the eating quality of meat in Japanese Black cattle. Therefore, the objective of this study was to identify loci associated with C18:1 in the intramuscular fat of the trapezius muscles in Japanese Black cattle using the Illumina BovineSNP50 BeadChip whole genome single nucleotide polymorphism (SNP) assay. We also eva ...
DOI:
10.1111/j.1365-2052.2010.02088.x
PubMed:
20590532

9. An integrated radiation hybrid map of bovine chromosome 18 that refines a critical region associated with multiple ocular defects in cattle

Author:
Abbasi, A.R.; Geriletoya,; Ihara, N.; Khalaj, M.; Sugimoto, Y.; Kunieda, T.
Source:
Animal genetics 2006 v.37 no.1 pp. 58-61
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; beef cattle; eye diseases; cattle diseases; congenital abnormalities; recessive genes; inheritance (genetics); loci; linkage (genetics); physical chromosome mapping; microsatellite repeats; genetic markers; genes;     Show all 13 Subjects
Abstract:
... Congenital multiple ocular defects (MOD) of Japanese black cattle is a hereditary ocular disorder with an autosomal recessive mode of inheritance showing developmental defects of the lens, retina and iris, persistent embryonic eye vascularization and microphthalmia. The MOD locus has been mapped by linkage analysis to a 6.6-cM interval on the proximal end of bovine chromosome 18, which corresponds ...
DOI:
10.1111/j.1365-2052.2005.01372.x
PubMed:
16441298

10. The bovine fatty acid binding protein 4 gene is significantly associated with marbling and subcutaneous fat depth in Wagyu x Limousin F₂ crosses

Author:
Michal, J.J.; Zhang, Z.W.; Gaskins, C.T.; Jiang, Z.
Source:
Animal genetics 2006 v.37 no.4 pp. 400-402
ISSN:
1365-2052
Subject:
Wagyu,   etc   ; beef cattle; Limousin (cattle breed); fatty acid-binding proteins; genes; marbling; subcutaneous fat; thickness; beef quality; beef; lipid metabolism; complementary DNA; nucleotide sequences; polymerase chain reaction; single nucleotide polymorphism; genetic markers; restriction fragment length polymorphism; genotype; quantitative trait loci;     Show all 19 Subjects
Abstract:
... Fatty acid binding protein 4 (FABP4), which is expressed in adipose tissue, interacts with peroxisome proliferator-activated receptors and binds to hormone-sensitive lipase and therefore, plays an important role in lipid metabolism and homeostasis in adipocytes. The objective of this study was to investigate associations of the bovine FABP4 gene with fat deposition. Both cDNA and genomic DNA seque ...
DOI:
10.1111/j.1365-2052.2006.01464.x

11. Quantitative trait loci with additive effects on palatability and fatty acid composition of meat in a Wagyu-Limousin F₂ population

Author:
Alexander, L.J.; MacNeil, M.D.; Geary, T.W.; Snelling, W.M.; Rule, D.C.; Scanga, J.A.
Source:
Animal genetics 2007 v.38 no.5 pp. 506-513
ISSN:
0268-9146
Subject:
Wagyu,   etc   ; acetyl-CoA carboxylase; additive gene effects; beef; chromosomes; fatty acid composition; fatty acid metabolism; fatty acids; fatty-acid synthase; genes; genome-wide association study; glucose transporters; lipid content; meat composition; palatability; progeny; quantitative trait loci; solutes; stearoyl-CoA desaturase; steers;     Show all 20 Subjects
Abstract:
... A whole-genome scan was conducted on 328 F₂ progeny in a Wagyu x Limousin cross to identify quantitative trait loci (QTL) affecting palatability and fatty acid composition of beef at an age-constant endpoint. We have identified seven QTL on five chromosomes involved in lipid metabolism and tenderness. None of the genes encoding major enzymes involved in fatty acid metabolism, such as fatty acid sy ...
DOI:
10.1111/j.1365-2052.2007.01643.x