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- Brogden, K.A.; Kalfa, V.C.; Ackermann, M.R.; Palmquist, D.E.; McCray, P.B. Jr.; Tack, B.F.
- Antimicrobial agents and chemotherapy 2001 v.45 no.1 pp. 331
- antimicrobial peptides; sheep; antimicrobial agents; antibacterial properties; respiratory tract diseases; disease control; minimum inhibitory concentration; bacterial infections; animal disease models; Mannheimia haemolytica; Pasteurella trehalosi; Salmonella enterica subsp. arizonae; Pasteurella multocida; Klebsiella pneumoniae; Corynebacterium pseudotuberculosis; Staphylococcus aureus; Pseudomonas aeruginosa; animal pathogenic bacteria; lungs; histopathology
- ... Cathelicidins are antimicrobial peptides from sheep (SMAP29 and SMAP34), rabbits (CAP11 and CAP18), rodents (CRAMP), and humans (FALL39, LL37, and h/CAP18). In a broth microdilution assay against nine ovine pathogens, SMAP29, SMAP34, mouse CRAMP, CAP18, CAP1831, CAP1828, CAP1822, and CAP1821a were the most active, with MICs as low as 0.6 μg/ml. Other cathelicidins were less active. In lambs with p ...
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