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- Hale Z. Toklu; Philip J. Scarpace; Yasemin Sakarya; Nataliya Kirichenko; Michael Matheny; Erin B. Bruce; Christy S. Carter; Drake Morgan; Nihal Tümer
- Applied Physiology, Nutrition, and Metabolism 2016 v.42 no.1 pp. 59-67
- NADP (coenzyme); Rattus norvegicus; body composition; enzyme activity; feeding behavior; food intake; free radical scavengers; hypothalamus; inflammation; leptin; males; metabolism; obesity; oxidative stress; phosphorylation; protein kinases; rats; signal transduction; transactivators; weight gain
- ... Hypothalamic inflammation and increased oxidative stress are believed to be mechanisms that contribute to obesity. 4-Hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl (tempol), a free radical scavenger, has been shown to reduce inflammation and oxidative stress. We hypothesized that brain infusion of tempol would reduce oxidative stress, and thus would reduce food intake and body weight and improve bod ...
- PubMed Central:
- Kirsten N. Bott; Sandra M. Sacco; Patrick C. Turnbull; Amanda B. Longo; Wendy E. Ward; Sandra J. Peters
- Applied Physiology, Nutrition, and Metabolism 2016 v.41 no.6 pp. 597-604
- bone density; bone strength; dual-energy X-ray absorptiometry; food intake; males; mandible (bone); mastication; materials testing; metabolism; micro-computed tomography; rats; skeleton; tibia; vertebrae
- ... Bone microarchitecture, bone mineral density (BMD), and bone strength are affected positively by impact activities such as running; however, there are discrepancies in the magnitude of these effects. These inconsistencies are mainly a result of varying training protocols, analysis techniques, and whether or not the skeletal sites measured are weight bearing. This study’s purpose was to determine t ...