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You searched for: Journal name Applied microbiology and biotechnology Remove constraint Journal name: Applied microbiology and biotechnology Publication year rev 7981-2019 Remove constraint Publication year rev: 7981-2019 Source 2019 v.103 no.4 Remove constraint Source: 2019 v.103 no.4
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1. Aqueous raw and ripe Pu-erh tea extracts alleviate obesity and alter cecal microbiota composition and function in diet-induced obese rats

Author:
Yun Xia; Donghong Tan; Roya Akbary; James Kong; Robert Seviour; Yunhong Kong
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1823-1835
ISSN:
0175-7598
Subject:
Bacteroidetes; Firmicutes; animal disease models; antibiotics; chemical composition; flavor; glyceraldehyde-3-phosphate dehydrogenase; glycolysis; intestinal microorganisms; metabolites; metagenomics; microbial communities; obesity; peptide elongation factors; polyphenols; prebiotics; rats; ribosomal RNA; secretion; sucrose; tea
Abstract:
... Pu-erh tea is attracting increased attention worldwide because of its unique flavor and health effects, but its impact on the composition and function of the gut microbiota remains unclear. The aim of this study was to investigate the effects of aqueous extracts of fermented (ripe) and non-fermented (raw) Pu-erh teas on the composition and function of the intestinal microbiota of rats with diet-in ...
DOI:
10.1007/s00253-018-09581-2

2. Biotransformation of dicarboxylic acids from vegetable oil–derived sources: current methods and suggestions for improvement

Author:
Heeseok Lee; Yohanes Eko Chandra Sugiharto; Hyeokwon Lee; Wooyoung Jeon; Jungoh Ahn; Hongweon Lee
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1545-1555
ISSN:
0175-7598
Subject:
alkanes; biotransformation; byproducts; dicarboxylic acids; fatty acid methyl esters; manufacturing; microorganisms; raw materials; renewable resources; vegetables
Abstract:
... Sustainable manufacture of dicarboxylic acids (DCAs), which are used as raw materials for multiple commercial products, has been an area of considerable research interest in recent years. Traditional chemical-based manufacture of DCAs suffers from limitations such as harsh operational conditions and generation of hazardous by-products. Microbiological methods involving DCA production depend on the ...
DOI:
10.1007/s00253-018-9571-7

3. Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO)

Author:
Nikola Lončar; Filippo Fiorentini; Gautier Bailleul; Simone Savino; Elvira Romero; Andrea Mattevi; Marco W. Fraaije
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1755-1764
ISSN:
0175-7598
Subject:
Escherichia coli; bacteria; biocatalysts; biotransformation; crystal structure; extremophiles; flavin-containing monooxygenase; genes; genome mining; melting point; pharmacokinetics; solvents; thermal stability
Abstract:
... The flavin-containing monooxygenases (FMOs) play an important role in drug metabolism but they also have a high potential in industrial biotransformations. Among the hitherto characterized FMOs, there was no thermostable representative, while such biocatalyst would be valuable for FMO-based applications. Through a targeted genome mining approach, we have identified a gene encoding for a putative F ...
DOI:
10.1007/s00253-018-09579-w

4. Cultivar and phosphorus effects on switchgrass yield and rhizosphere microbial diversity

Author:
Anne Sawyer; Christopher Staley; John Lamb; Craig Sheaffer; Thomas Kaiser; Jessica Gutknecht; Michael J. Sadowsky; Carl Rosen
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1973-1987
ISSN:
0175-7598
Subject:
Panicum virgatum; USDA; agricultural land; bioenergy; biomass production; clay loam soils; community structure; cultivars; energy crops; fertilizer application; fungal communities; grasses; indigenous species; microbiome; nutrient uptake; perennials; phosphorus; phosphorus fertilizers; rhizosphere
Abstract:
... Switchgrass (Panicum virgatum L.) is a native perennial grass identified as a promising biofuel crop for production on marginal agricultural lands. As such, research into switchgrass fertility and the switchgrass rhizosphere microbiome has been ongoing in an effort to increase production sustainability. We examined the effects of cultivar and phosphorus (P) fertilization on biomass yield, P remova ...
DOI:
10.1007/s00253-018-9535-y
CHORUS:
10.1007/s00253-018-9535-y

5. Design, expression, and characterization of a novel cecropin A-derived peptide with high antibacterial activity

Author:
Meng Wang; Jinglian Lin; Qiuli Sun; Kaiwen Zheng; Yi Ma; Jufang Wang
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1765-1775
ISSN:
0175-7598
Subject:
Escherichia coli; Gram-negative bacteria; antibacterial properties; antibiotics; bioinformatics; blood serum; cecropins; hemolysis; mutation; pepsin; peptidase K; thermal stability; toxicity; trypsin
Abstract:
... In recent years, antimicrobial peptides have received increased interest and are potential substitutes for antibiotics. However, natural antimicrobial peptides are always toxic to mammalian cells and usually exhibit weak antibacterial activity, which restrict their wide application. In this study, a novel antibacterial peptide named PEW300 was designed with three mutations to the parental peptide ...
DOI:
10.1007/s00253-018-09592-z

6. Effects of long-term straw incorporation on lignin accumulation and its association with bacterial laccase-like genes in arable soils

Author:
Shuzhen Feng; Yirong Su; Xunyang He; Yajun Hu; Zhenhua Zhang; Hongbo He; Khalil Kariman; Jinshui Wu; Xiangbi Chen
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1961-1972
ISSN:
0175-7598
Subject:
Acidobacteria; Thermotogae; arable soils; bacterial communities; enzyme activity; genes; highlands; laccase; lignin; lignin content; limestone soils; nitrogen; straw; variance
Abstract:
... In this study, we aimed to investigate lignin accumulation and its relationship with the composition of bacterial laccase-like genes in three arable lands (i.e., upland limestone soil (UL), upland red soil (UR), and upland-paddy rotation red soil (UPR)), which are subjected to long-term straw incorporation. After 9–13 years of straw incorporation, the lignin content significantly increased from 33 ...
DOI:
10.1007/s00253-018-9563-7

7. Effects of the natural restoration time of abandoned farmland in a semiarid region on the soil denitrification rates and abundance and community structure of denitrifying bacteria

Author:
Honglei Wang; Jianqiao Han; Na Deng; Shaoshan An
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1939-1951
ISSN:
0175-7598
Subject:
abandoned land; agricultural land; ammonium nitrogen; denitrification; denitrifying bacteria; ecosystems; gas emissions; genes; grazing; greenhouse gases; leaching; nitrate nitrogen; nitrogen; nitrous oxide; population growth; semiarid zones; soil density
Abstract:
... Denitrification accounts for the production of mobile forms of nitrogen (N) for plant uptake, N leaching, and gaseous losses. However, few studies have investigated the potential effects of the natural restoration age on denitrification rates and denitrifying microorganisms, especially in fragile ecosystems in semiarid regions. The potential N gas (N₂O and N₂) emissions and denitrification rates s ...
DOI:
10.1007/s00253-018-09575-0

8. Enrichment of cordycepin for cosmeceutical applications: culture systems and strategies

Author:
Phongsakorn Kunhorm; Nipha Chaicharoenaudomrung; Parinya Noisa
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1681-1691
ISSN:
0175-7598
Subject:
Cordyceps; bioactive properties; biosynthesis; biotechnology; cordycepin; cosmetics; drug therapy; ingredients; liquids; models; solid state fermentation; China
Abstract:
... Cordyceps spp. is the herbal medication initially used in China and has been reported as the unique resource of cordycepin. Cordycepin exhibits many health benefits, including anti-photoaging and anti-pigmentation; therefore, it potentially is a bioactive ingredient of cosmetic products. In order to enrich cordycepin content in Cordyceps, two artificial cultivation procedures, which are solid-stat ...
DOI:
10.1007/s00253-019-09623-3

9. Expression of cry genes in Bacillus thuringiensis biotechnology

Author:
Qi Peng; Qingyue Yu; Fuping Song
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1617-1626
ISSN:
0175-7598
Subject:
Bacillus thuringiensis; biotechnology; crystal proteins; crystals; genes; hosts; insecticidal proteins; niches; research and development; spore-forming bacteria; sporulation
Abstract:
... Bacillus thuringiensis is a gram-positive, spore-forming bacterium that produces insecticidal crystal proteins during sporulation. The production of these crystals results primarily from the expression of cry genes. In this review, we focus on the expression and application of cry genes directed by both cry gene promoters and non-cry gene promoters in different hosts. However, not all cry genes an ...
DOI:
10.1007/s00253-018-9552-x

10. Glycerol inhibition of melanin biosynthesis in the environmental Aeromonas salmonicida 34melT

Author:
María Elisa Pavan; Esmeralda Solar Venero; Diego E. Egoburo; Esteban E. Pavan; Nancy I. López; M. Julia Pettinari
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1865-1876
ISSN:
0175-7598
Subject:
4-hydroxyphenylpyruvate dioxygenase; Aeromonas salmonicida subsp. pectinolytica; amino acids; biosynthesis; carbon; culture media; glycerol; glyphosate; melanin; melanization; oxidation; protein composition; protein secretion; proteins
Abstract:
... The environmental strain Aeromonas salmonicida subsp. pectinolytica 34melᵀ produces abundant melanin through the homogentisate pathway in several culture media, but unexpectedly not when grown in a medium containing glycerol. Using this observation as a starting point, this study investigated the underlying causes of the inhibition of melanin synthesis by glycerol, to shed light on factors that af ...
DOI:
10.1007/s00253-018-9545-9

11. Grey mould disease of strawberry in northern Germany: causal agents, fungicide resistance and management strategies

Author:
Roland W. S. Weber; Matthias Hahn
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1589-1597
ISSN:
0175-7598
Subject:
Botrytis cinerea; benzimidazoles; boscalid; cyprodinil; fenhexamid; fludioxonil; fungicide resistance; gray mold; iprodione; strawberries; surveys; Germany
Abstract:
... Grey mould, the most important disease of strawberry worldwide, is caused by Botrytis cinerea and a few additional Botrytis spp. Fungicide resistance is a growing problem and has become a limiting factor in strawberry production. In northern Germany, an annual survey of Botrytis isolates from commercial strawberry fields in 2010 to 2017 has revealed high (> 20%) frequencies of resistance to quinon ...
DOI:
10.1007/s00253-018-09590-1

12. Hydroperoxides derived from marine sources: origin and biological activities

Author:
Vera A. Vil; Tatyana A. Gloriozova; Alexander O. Terent’ev; Nick Savidov; Valery M. Dembitsky
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1627-1642
ISSN:
0175-7598
Subject:
Chlorophyta; Plasmodium; algae; antiprotozoal properties; bacteria; corals; fungi; hydroperoxides; metabolites; molluscs
Abstract:
... Hydroperoxides are a small and interesting group of biologically active natural marine compounds. All these metabolites contain a group (R-O-O-H). In this mini-review, studies of more than 80 hydroperoxides isolated from bacteria, fungi, algae, and marine invertebrates are described. Hydroperoxides from the red, brown, and green algae exhibit high antineoplastic, anti-inflammatory, and antiprotozo ...
DOI:
10.1007/s00253-018-9560-x

13. Impaired oxidative stress and sulfur assimilation contribute to acid tolerance of Corynebacterium glutamicum

Author:
Ning Xu; Hongfang Lv; Liang Wei; Yuan Liang; Jiansong Ju; Jun Liu; Yanhe Ma
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1877-1891
ISSN:
0175-7598
Subject:
Corynebacterium glutamicum; acid tolerance; biochemical pathways; cell viability; copper; fermentation; genes; genetic improvement; iron; oxidative stress; reactive oxygen species; sulfur; transcriptomics
Abstract:
... The industrial organism Corynebacterium glutamicum is often subjected to acid stress during large-scale fermentation for the production of bio-based chemicals. The capacity of the cells to thrive in acidic environments is a prerequisite for achieving high product yields. In this study, we obtained an acid-adapted strain using an adaptive laboratory evolution strategy. Physiological characterizatio ...
DOI:
10.1007/s00253-018-09585-y

14. In vitro and in vivo investigations of probiotic properties of lactic acid bacteria isolated from Chinese traditional sourdough

Author:
Yang Li; Tongjie Liu; Minjie Zhao; Hao Zhong; Wenxin Luo; Fengqin Feng
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1893-1903
ISSN:
0175-7598
Subject:
Lactobacillus plantarum; bile resistance; blood serum; gastric juice; gastrointestinal system; health promotion; high density lipoprotein cholesterol; intestinal microorganisms; lactic acid bacteria; low density lipoprotein cholesterol; males; metabolic syndrome; mice; pH; pathogens; probiotics; ribosomal RNA; sequence analysis; sourdough; tumor necrosis factor-alpha
Abstract:
... A total of 88 lactic acid bacteria (LAB) strains were isolated from Chinese traditional sourdough and five of them were selected based on their bile resistance. All the five strains were identified as Lactobacillus plantarum by 16S rRNA gene sequencing. In vitro probiotic properties of the L. plantarum strains including tolerance to simulated gastrointestinal conditions, aggregation activity, and ...
DOI:
10.1007/s00253-018-9554-8

15. Landomycin biosynthesis and its regulation in Streptomyces

Author:
Oleksandr Yushchuk; Madan Kharel; Iryna Ostash; Bohdan Ostash
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1659-1665
ISSN:
0175-7598
Subject:
Streptomyces; antineoplastic activity; biochemical pathways; biosynthesis; exports; genetic variation; glycosides; mammals; multigene family; polyketides
Abstract:
... This mini-review is centered on genetic aspects of biosynthesis of landomycins (La), a family of angucycline polyketides. From the very discovery in the 1990s, La were noted for unusual structure and potent anticancer properties. La are produced by a few actinobacteria that belong to genus Streptomyces. Biochemical logic behind the production of La aglycon and glycoside halves and effects of La on ...
DOI:
10.1007/s00253-018-09601-1

16. Mid1 affects ion transport, cell wall integrity, and host penetration of the entomopathogenic fungus Metarhizium acridum

Author:
Mushan Xie; Xuan Zhou; Yuxian Xia; Yueqing Cao
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1801-1810
ISSN:
0175-7598
Subject:
Metarhizium; appressoria; bioassays; calcium; calcium channels; calcium signaling; cations; cell walls; chelating agents; culture media; entomopathogenic fungi; ethylene glycol tetraacetic acid; fungal growth; gene expression regulation; genes; heat; hemocoel; homeostasis; insects; iron; lithium; magnesium; manganese; mutants; phenotype; stress tolerance; ultraviolet radiation; virulence; wings
Abstract:
... Calcium signaling plays important roles in stress tolerance and virulence in fungi. Mid1, an accessory protein of Cch1 calcium channel, has been discussed in baker’s yeast and some filamentous fungi. However, functions of the Mid1 gene in entomopathogenic fungi are not clear. In this study, the Mid1 gene was functionally characterized by deleting it in the entomopathogenic fungus Metarhizium acrid ...
DOI:
10.1007/s00253-018-09589-8

17. Morphology engineering for enhanced production of medium-chain-length polyhydroxyalkanoates in Pseudomonas mendocina NK-01

Author:
Fengjie Zhao; Ting Gong; Xiangsheng Liu; Xu Fan; Rui Huang; Ting Ma; Shufang Wang; Weixia Gao; Chao Yang
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1713-1724
ISSN:
0175-7598
Subject:
Pseudomonas mendocina; bioplastics; biotechnology; cell division; cytoskeleton; gene overexpression; gene targeting; genes; microorganisms; peptidoglycans; petroleum; polyhydroxyalkanoates; renewable resources
Abstract:
... Polyhydroxyalkanoates (PHAs) can be produced by microorganisms from renewable resources and are regarded as promising bioplastics to replace petroleum-based plastics. A medium-chain-length PHAs (mcl-PHA)-producing strain Pseudomonas mendocina NK-01 was isolated previously by our lab and its whole-genome sequence is currently available. Morphology engineering of manipulating cell morphology–related ...
DOI:
10.1007/s00253-018-9546-8

18. Optimization of the Gal4/UAS transgenic tools in zebrafish

Author:
Yunsheng Zhang; Jiawei Ouyang; Jingrong Qie; Gongyuan Zhang; Liangguo Liu; Pinhong Yang
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1789-1799
ISSN:
0175-7598
Subject:
DNA methylation; Danio rerio; cytotoxicity; embryo (animal); genetic engineering; genetically modified organisms; screening; transgenes
Abstract:
... The Gal4/UAS system provides a powerful tool to analyze the function of genes. The system has been employed extensively in zebrafish; however, cytotoxicity of Gal4 and methylation of UAS can hinder future applications of Gal4/UAS in zebrafish. In this study, we provide quantitative data on the cytotoxicity of Gal4-FF and KalTA4 in zebrafish embryos. A better balance between induction efficiency an ...
DOI:
10.1007/s00253-018-09591-0

19. Probiotic therapy in Helicobacter pylori infection: a potential strategy against a serious pathogen?

Author:
Nuzhat Qureshi; Ping Li; Qing Gu
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1573-1588
ISSN:
0175-7598
Subject:
Helicobacter pylori; adverse effects; animal pathogens; antagonism; antibiotics; guidelines; inflammation; neoplasms; probiotics; proton pump inhibitors; therapeutics; tissues; vaccines
Abstract:
... Helicobacter pylori is a highly prevalent human pathogen responsible for chronic inflammation of the gastric tissues, gastroduodenal ulcers, and cancer. The treatment includes a pair of antibiotics with a proton pump inhibitor PPI. Despite the presence of different treatments, the infection rate is still increasing both in developed and developing states. The challenge of treatment failure is grea ...
DOI:
10.1007/s00253-018-09580-3

20. Regulation of the phosphate metabolism in Streptomyces genus: impact on the secondary metabolites

Author:
Carlos Barreiro; Miriam Martínez-Castro
Source:
Applied microbiology and biotechnology 2019 v.103 no.4 pp. 1643-1658
ISSN:
0175-7598
Subject:
Streptomyces avermitilis; Streptomyces coelicolor; Streptomyces lividans; Streptomyces lydicus; Streptomyces natalensis; antibiotics; metabolism; phosphates; regulon; secondary metabolites
Abstract:
... The analysis of the inorganic phosphate effect over the antibiotics production is a long-distance history in the Streptomyces genus, which began almost at the same time that Michael Ende published his book entitled The Neverending Story. In some way, the unveiling of the pho regulon and its influence over the secondary metabolites production is an unfinished story, which keeps this subject as a tr ...
DOI:
10.1007/s00253-018-09600-2