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- Flores, Dayana; Panic, Gordana; Braissant, Olivier; Keiser, Jennifer
- Applied microbiology and biotechnology 2016 v.100 no.2 pp. 837-846
- Ancylostoma ceylanicum, etc ; Necator americanus; Trichuris muris; adults; detection limit; dose response; drug resistance; drugs; heat; hookworms; ivermectin; levamisole; morbidity; nematicides; screening; viability; wavelet; Show all 17 Subjects
- ... Soil-transmitted helminths, which affect the poorest communities, worldwide cause a range of symptoms and morbidity, yet few treatment options are available and drug resistance is a concern. To improve and accelerate anthelminthic drug discovery, novel drug screening tools such as isothermal microcalorimetry (IMC) have been tested with great potential. In this study, we used a novel microcalorimet ...