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You searched for: Journal Aquatic toxicology Remove constraint Journal: Aquatic toxicology Publication Year 2009 Remove constraint Publication Year: 2009 Source 2009 v.92 no.3 Remove constraint Source: 2009 v.92 no.3 Subject endocrine-disrupting chemicals Remove constraint Subject: endocrine-disrupting chemicals
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1. Development of biomarkers of stress related to endocrine disruption in gastropods: Alkali-labile phosphates, protein-bound lipids and vitellogenin-like proteins

Author:
Gagnaire, Beatrice; Gagné, François; André, Chantale; Blaise, Christian; Abbaci, Khedidja; Budzinski, Hélène; Dévier, Marie-Hélène; Garric, Jeanne
Source:
Aquatic toxicology 2009 v.92 no.3 pp. 155-167
ISSN:
0166-445X
Subject:
Gastropoda; snails; endocrine-disrupting chemicals; biomarkers; abiotic stress; vitellogenin; proteins; gonads; histology; phosphates; lipids; animal reproduction; reproductive toxicology; France
Abstract:
... The occurrence in aquatic environments of compounds capable of acting as endocrine disruptors (ED) is of concern for wildlife. Elevated levels of the egg-yolk precursor protein vitellogenin (Vg) are widely accepted as a biomarker for xenoestrogen exposure in aquatic organisms. The purpose of this study was to develop a method for tracking changes in levels of Vg-like proteins in gastropods. Vg-lik ...
DOI:
10.1016/j.aquatox.2009.01.012
PubMed:
19269698

2. Endocrine disrupting chemicals in fish: Developing exposure indicators and predictive models of effects based on mechanism of action

Author:
Ankley, Gerald T.; Bencic, David C.; Breen, Michael S.; Collette, Timothy W.; Conolly, Rory B.; Denslow, Nancy D.; Edwards, Stephen W.; Ekman, Drew R.; Garcia-Reyero, Natalia; Jensen, Kathleen M.; Lazorchak, James M.; Martinović, Dalma; Miller, David H.; Perkins, Edward J.; Orlando, Edward F.; Villeneuve, Daniel L.; Wang, Rong-Lin; Watanabe, Karen H.
Source:
Aquatic toxicology 2009 v.92 no.3 pp. 168-178
ISSN:
0166-445X
Subject:
endocrine-disrupting chemicals; fish; animal models; Pimephales promelas; minnows; Danio rerio; toxicity; mechanism of action; bioinformatics; genomics; metabolomics; transcriptomics; proteomics; prediction; models
Abstract:
... Knowledge of possible toxic mechanisms (or modes) of action (MOA) of chemicals can provide valuable insights as to appropriate methods for assessing exposure and effects, thereby reducing uncertainties related to extrapolation across species, endpoints and chemical structure. However, MOA-based testing seldom has been used for assessing the ecological risk of chemicals. This is in part because pas ...
DOI:
10.1016/j.aquatox.2009.01.013
PubMed:
19261338