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You searched for: Journal Aquatic toxicology Remove constraint Journal: Aquatic toxicology Publication Year 2009 Remove constraint Publication Year: 2009 Subject gene expression Remove constraint Subject: gene expression Subject messenger RNA Remove constraint Subject: messenger RNA
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1. Hepatic and vascular mRNA expression in adult zebrafish (Danio rerio) following exposure to benzo-a-pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin

Author:
Bugiak, Brandie; Weber, Lynn P.
Source:
Aquatic toxicology 2009 v.95 no.4 pp. 299-306
ISSN:
0166-445X
Subject:
messenger RNA; liver; antagonists; receptors; gene expression; cytochrome P-450; cardiovascular system; fish; Danio rerio; agonists; benzopyrenes; tetrachlorodibenzo-p-dioxin
Abstract:
... Developmental exposure to aryl hydrocarbon receptor (AhR) agonists in fish causes severe defects in the cardiovascular system. However, the effects of acute AhR agonist exposure on the adult fish cardiovascular system are not clear. We hypothesized that AhR-mediated changes in adult vascular tissue gene expression would differ from that of hepatic tissue. Therefore, zebrafish (Danio rerio) were in ...
DOI:
10.1016/j.aquatox.2009.03.009
PubMed:
19403181

2. PAH biomarker responses in polar cod (Boreogadus saida) exposed to benzo(a)pyrene

Author:
Nahrgang, Jasmine; Camus, Lionel; Gonzalez, Patrice; Goksøyr, Anders; Christiansen, Jørgen S.; Hop, Haakon
Source:
Aquatic toxicology 2009 v.94 no.4 pp. 309-319
ISSN:
0166-445X
Subject:
water pollution; petroleum; messenger RNA; polycyclic aromatic hydrocarbons; biomarkers; Boreogadus; metabolites; transcription (genetics); gene expression; Western blotting; enzyme-linked immunosorbent assay; bile; gene induction; cod (fish); benzopyrenes; enzyme activity; oxidative stress; Arctic region
Abstract:
... With expanding oil and gas activities into the Arctic region, there is a need to evaluate the induction capacity of polycyclic aromatic hydrocarbon (PAH) biomarkers on Arctic marine organisms and to test analytical methods that have been optimized for their temperate counterparts. Polar cod Boreogadus saida were injected intraperitoneally with cod liver oil (solvent control), 6.6±3.7, 85±48 or 378 ...
DOI:
10.1016/j.aquatox.2009.07.017
PubMed:
19709761

3. Copper toxicity in gills of the teleost fish, Oreochromis niloticus: Effects in apoptosis induction and cell proliferation

Author:
Monteiro, Sandra Mariza; dos Santos, Nuno M.S.; Calejo, Margarida; Fontainhas-Fernandes, António; Sousa, Mário
Source:
Aquatic toxicology 2009 v.94 no.3 pp. 219-228
ISSN:
0166-445X
Subject:
water pollution; copper; cytotoxicity; Oreochromis niloticus; tilapia (common name); gills; apoptosis; cell proliferation; DNA fragmentation; messenger RNA; gene expression; gene induction
Abstract:
... Recent in vitro studies have demonstrated that copper may induce apoptosis triggering the activation of caspase-3, a central effector of apoptotic cell death. However, the precise mechanism of copper-induced apoptosis is still unclear, even less so in Oreochromis niloticus where no caspase genes have been reported so far. This study aimed to assess the in vivo role of copper in apoptosis induction ...
DOI:
10.1016/j.aquatox.2009.07.008
PubMed:
19656581

4. Effects of environmental concentrations of the antiepilectic drug carbamazepine on biomarkers and cAMP-mediated cell signaling in the mussel Mytilus galloprovincialis

Author:
Martin-Diaz, Laura; Franzellitti, Silvia; Buratti, Sara; Valbonesi, Paola; Capuzzo, Antonio; Fabbri, Elena
Source:
Aquatic toxicology 2009 v.94 no.3 pp. 177-185
ISSN:
0166-445X
Subject:
drugs; environmental exposure; Mytilus galloprovincialis; mussels; biomarkers; oxidative stress; enzyme activity; cyclic AMP; messenger RNA; gene expression; protein kinases
Abstract:
... Pharmaceuticals represent a diverse collection of thousands of bioactive chemicals used in human and veterinary medicine. The increased consumption, together with the recent development of more sensitive analytical techniques, has identified these as emerging contaminants in the aquatic environment. According to many investigations pharmaceuticals do not cause acute toxic effects in organisms when ...
DOI:
10.1016/j.aquatox.2009.06.015
PubMed:
19632730

5. Transcript profiling and DNA damage in the European eel (Anguilla anguilla L.) exposed to 7,12-dimethylbenz[a]anthracene

Author:
Nogueira, Patrícia; Lourenço, Joana; Rodriguez, Eleazar; Pacheco, Mário; Santos, Conceição; Rotchell, Jeanette M.; Mendo, Sónia
Source:
Aquatic toxicology 2009 v.94 no.2 pp. 123-130
ISSN:
0166-445X
Subject:
water pollution; polycyclic aromatic hydrocarbons; Anguilla anguilla; eel; genotoxicity; DNA damage; biomarkers; cytochrome P-450; messenger RNA; gene expression; polymerase chain reaction; transcription factors
Abstract:
... The molecular responses induced during and after an acute exposure to 7,12-dimethylbenz[a]anthracene (DMBA) were analysed in liver, gill and blood cells of juvenile Anguilla anguilla with the aim of developing molecular biomarkers of environmental PAH pollution. Changes in the mRNA expression levels of the cell cycle checkpoint-related rad1 gene and the mRNAs of differentially expressed genes by s ...
DOI:
10.1016/j.aquatox.2009.06.007
PubMed:
19586669

6. Interaction of fish aryl hydrocarbon receptor paralogs (AHR1 and AHR2) with the retinoblastoma protein

Author:
Merson, Rebeka R.; Karchner, Sibel I.; Hahn, Mark E.
Source:
Aquatic toxicology 2009 v.94 no.1 pp. 47-55
ISSN:
0166-445X
Subject:
Fundulus heteroclitus; tetrachlorodibenzo-p-dioxin; water pollution; receptors; cytotoxicity; in vitro studies; messenger RNA; gene expression; complementary DNA; molecular cloning; polymerase chain reaction; neoplasms; DNA primers; nucleotide sequences
Abstract:
... The aryl hydrocarbon receptor (AHR) mediates the toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds. In some mammalian cell lines, TCDD induces G1 cell cycle arrest, which depends on an interaction between the AHR and the retinoblastoma tumor suppressor (RB). Mammals possess one AHR, whereas fishes possess two or more AHR paralogs that differ in the domains important ...
DOI:
10.1016/j.aquatox.2009.05.015
PubMed:
19539383
PubMed Central:
PMC2833323

7. Gene expression profiling of copper-induced responses in the intertidal copepod Tigriopus japonicus using a 6K oligochip microarray

Author:
Ki, Jang-Seu; Raisuddin, Sheikh; Lee, Kyun-Woo; Hwang, Dae-Sik; Han, Jeonghoon; Rhee, Jae-Sung; Kim, Il-Chan; Park, Heum Gi; Ryu, Jae-Chun; Lee, Jae-Seong
Source:
Aquatic toxicology 2009 v.93 no.4 pp. 177-187
ISSN:
0166-445X
Subject:
Copepoda; pollutants; copper; messenger RNA; gene expression; genomics; microarray technology; toxicity testing; ecotoxicology; polymerase chain reaction
Abstract:
... The intertidal copepod Tigriopus japonicus has shown promising results in classical acute and chronic toxicity studies. Recently, a large number of genes have been identified from this species and their mRNA expression has been studied independently against exposure to marine environmental pollutants. T. japonicus is a promising organism for the study of mechanistic aspects of marine environmental ...
DOI:
10.1016/j.aquatox.2009.04.004
PubMed:
19515434

8. Gene expression profiling in the deep water horse mussel Modiolus modiolus (L.) located near a marine municipal wastewater outfall

Author:
Veldhoen, Nik; Lowe, Christopher J.; Davis, Céline; Mazumder, Asit; Helbing, Caren C.
Source:
Aquatic toxicology 2009 v.93 no.2-3 pp. 116-124
ISSN:
0166-445X
Subject:
water pollution; effluents; mussels; messenger RNA; genotoxicity; DNA primers; polymerase chain reaction; gene expression; transcription (genetics); nucleotide sequences; wastewater; British Columbia
Abstract:
... The marine bivalve Modiolus modiolus (L.) is a sentinel species used for the assessment of potential biological exposure to anthropogenic contaminants in benthic environments. Herein, we have developed real-time quantitative polymerase chain reaction assays for 12 specific mRNAs. The levels of each mRNA transcript were evaluated in adductor muscle, gonad, and hepatopancreas tissue collected from a ...
DOI:
10.1016/j.aquatox.2009.04.002
PubMed:
19450888

9. Physiological responses to mercury in feral carp populations inhabiting the low Ebro River (NE Spain), a historically contaminated site

Author:
Navarro, Anna; Quirós, Laia; Casado, Marta; Faria, Melissa; Carrasco, Luís; Benejam, Lluís; Benito, Josep; Díez, Sergi; Raldúa, Demetrio; Barata, Carlos; Bayona, Josep M.; Piña, Benjamin
Source:
Aquatic toxicology 2009 v.93 no.2-3 pp. 150-157
ISSN:
0166-445X
Subject:
rivers; water pollution; mercury; Cyprinus carpio; carp; feral animals; physiological response; bioaccumulation; toxicity; liver; kidneys; muscles; oxidative stress; DNA damage; glutathione; metallothionein; gene expression; messenger RNA; biomarkers; Spain
Abstract:
... The low Ebro River course (Northeast Spain) is historically affected by mercury pollution due to a chlor-alkali plant operating at the town of Flix for more than a century. River sediments analysed during the last 10 years showed high mercury levels in the river section starting just downstream the factory and spanning some 90km, down to the river delta. The possible environmental impact was studi ...
DOI:
10.1016/j.aquatox.2009.04.009
PubMed:
19482362

10. Androgenic effects of a Canadian bleached kraft pulp and paper effluent as assessed using threespine stickleback (Gasterosteus aculeatus)

Author:
Wartman, C.A.; Hogan, N.S.; Hewitt, L.M.; McMaster, M.E.; Landman, M.J.; Taylor, S.; Kovacs, T.G.; van den Heuvel, M.R.
Source:
Aquatic toxicology 2009 v.92 no.3 pp. 131-139
ISSN:
0166-445X
Subject:
pulp and paper mill effluents; bleached kraft pulp; water pollution; Gasterosteus aculeatus; reproductive toxicology; androgens; estrogens; steroidogenesis; animal reproduction; vitellogenin; polymerase chain reaction; messenger RNA; gene expression; enzyme activity
Abstract:
... The presence of unidentified estrogens and androgens in effluents from pulp and paper mills is well documented. However, their role in effluent effects on fish reproduction remains unclear. The objective of this study was to investigate the hypothesis that reproductive impacts of a modern pulp mill effluent are mediated by androgens and/or estrogens in the effluent. Male and female threespine stic ...
DOI:
10.1016/j.aquatox.2009.02.003
PubMed:
19261340

11. Changes of thyroid hormone levels and related gene expression in Chinese rare minnow (Gobiocypris rarus) during 3-amino-1,2,4-triazole exposure and recovery

Author:
Li, Wei; Zha, Jinmiao; Spear, Philip A.; Li, Zhaoli; Yang, Lihua; Wang, Zijian
Source:
Aquatic toxicology 2009 v.92 no.1 pp. 50-57
ISSN:
0166-445X
Subject:
water pollution; amitrole; endocrine-disrupting chemicals; minnows; thyroid hormones; messenger RNA; gene expression; histopathology; liver; blood plasma; biomarkers
Abstract:
... Thyroid hormones (THs) play an important role in the development and metabolism of fish through their influences on genetic transcription and are targets for endocrine disruptive agents in the aquatic environment. Amitrole is a pesticide potentially interfering with thyroid hormone regulation. In this study, the rare minnow (Gobiocypris rarus) was exposed to different levels of 3-amino-1,2,4-triaz ...
DOI:
10.1016/j.aquatox.2009.01.006
PubMed:
19223083

12. Nickel and binary metal mixture responses in Daphnia magna: Molecular fingerprints and (sub)organismal effects

Author:
Vandenbrouck, Tine; Soetaert, Anneleen; van der Ven, Karlijn; Blust, Ronny; De Coen, Wim
Source:
Aquatic toxicology 2009 v.92 no.1 pp. 18-29
ISSN:
0166-445X
Subject:
water pollution; nickel; cadmium; lead; heavy metals; Daphnia magna; aquatic arthropods; messenger RNA; gene expression; transcription (genetics); microarray technology; multivariate analysis; toxicity testing; cytotoxicity
Abstract:
... The recent development of a custom cDNA microarray platform for one of thé standard organisms in aquatic toxicology, Daphnia magna, opened up new ways to mechanistic insights of toxicological responses. In this study, the mRNA expression of several genes and (sub)organismal responses (Cellular Energy Allocation, growth) were assayed after short-term waterborne metal exposure. Microarray analysis ...
DOI:
10.1016/j.aquatox.2008.12.012
PubMed:
19187980

13. Photoperiod and temperature influence endocrine disruptive chemical-mediated effects in male adult zebrafish

Author:
Jin, Yuanxiang; Chen, Rujia; Sun, Liwei; Liu, Weiping; Fu, Zhengwei
Source:
Aquatic toxicology 2009 v.92 no.1 pp. 38-43
ISSN:
0166-445X
Subject:
water pollution; endocrine-disrupting chemicals; Danio rerio; water temperature; photoperiod; genes; transcription factors; messenger RNA; gene expression; estradiol; vitellogenin
Abstract:
... Potential adverse effects of endocrine-disrupting chemicals (EDCs) in human and wildlife have become a major research topic. However, little is known about the effects of ambient conditions, including temperature and photoperiod, on endocrine disruption in zebrafish. We found that zebrafish hepatic estrogen-responsive gene transcription levels were greatly affected by temperature and photoperiod. ...
DOI:
10.1016/j.aquatox.2009.01.003
PubMed:
19223081

14. Effect of nonylphenol on giant freshwater prawn (Macrobrachium rosenbergii) via oral treatment: Toxicity and messenger RNA expression of hemocyte genes

Author:
Sung, Hung-Hung; Ye, Yu-Zhi
Source:
Aquatic toxicology 2009 v.91 no.3 pp. 270-277
ISSN:
0166-445X
Subject:
phenols; nonionic surfactants; water pollution; endocrine-disrupting chemicals; Macrobrachium rosenbergii; shrimp; dietary exposure; genotoxicity; messenger RNA; hemocytes; gene expression; Lactobacillus; bacterial infections; disease resistance; immune response
Abstract:
... A previous in vitro study has indicated that two alkylphenol ethoxylates (APEs) could potentially damage hemocytes and influence cellular immunity of prawns (Macrobrachium rosenbergii). The aim of this study was to investigate the effects of nonylphenol (NP) on susceptibility to a pathogen and on the mRNA expression of hemocyte genes, including four immune-related genes. NP at different concentrat ...
DOI:
10.1016/j.aquatox.2008.11.017
PubMed:
19131121