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1. Evaluation of DNA damage and physiological responses in Nile tilapia, Oreochromis niloticus (Linnaeus, 1758) exposed to sub-lethal diclofenac (DCF)

Author:
Kumar, Saurav,   et al.   ; Pandey, Pramod K.; Ajima, Malachy N.O.; Kumar, Kundan; Poojary, Nalini;     Show all 5 Authors
Source:
Aquatic toxicology 2017 v.186 pp. 205-214
ISSN:
0166-445X
Subject:
DNA; DNA damage; Oreochromis niloticus; adenosinetriphosphatase; aquatic ecosystems; bioaccumulation; biomarkers; catalase; diclofenac; drugs; ecotoxicology; environmental monitoring; erythrocytes; fish; gel electrophoresis; genotoxicity; glutathione; glutathione peroxidase; glutathione transferase; hemoglobin; leukocyte count; lipid peroxidation; liver; oxidative stress; physiological response; sodium; superoxide dismutase
Abstract:
... The frequent bioaccumulation of pharmaceuticals in the aquatic ecosystem has raised a concern about their possible ecotoxicological consequences. DNA damage, haematological changes and activities of oxidative stress enzymes in Nile tilapia, Oreochromis niloticus in response to diclofenac (DCF) exposure were investigated for up to 60 days at the concentrations of 0.17, 0.34 and 0.68mgL−1 in the fis ...
DOI:
10.1016/j.aquatox.2017.03.007