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- Lim, Ji Ye; Liu, Chun; Hu, Kang-Quan; Smith, Donald E.; Wang, Xiang-Dong
- Archives of biochemistry and biophysics 2018 v.654 pp. 1-9
- antioxidants; beta oxidation; carotenoids; cholesterol; cholesterol metabolism; enzymes; fatty acids; fatty liver; homeostasis; humans; lipogenesis; mice; microRNA; oxidative stress; triacylglycerols
- ... β-Carotene-15, 15′-oxygenase (BCO1) and β-carotene-9′, 10′-oxygenase (BCO2) are essential enzymes in carotenoid metabolism. While BCO1/BCO2 polymorphisms have been associated with alterations to human and animal carotenoid levels, experimental studies have suggested that BCO1 and BCO2 may have specific physiological functions beyond the cleavage of carotenoids. In the present study, we investigate ...