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- Niki, Etsuo
- Archives of biochemistry and biophysics 2016 v.595 pp. 19-24
- antioxidants; cholesterol; distress; human health; lipid peroxidation; oxidants; oxidative stress; polyunsaturated fatty acids; reactive oxygen species; vitamin E
- ... There is a growing consensus that reactive oxygen species (ROS) are not just associated with various pathologies, but that they act as physiological redox signaling messenger with important regulatory functions. It is sometimes stated that “if ROS is a physiological signaling messenger, then removal of ROS by antioxidants such as vitamins E and C may not be good for human health.” However, it shou ...
- Niki, Etsuo, et al. Show all 5 Authors
- Archives of biochemistry and biophysics 2017
- arachidonic acid; biomarkers; cholesterol; enzymes; free radicals; humans; lipid peroxidation; oxidants; oxidation; positional isomers; singlet oxygen; stereoisomers
- ... Free and ester forms of unsaturated fatty acids and cholesterol are oxidized in vivo by multiple oxidants to give diverse products. Some lipid oxidation is mediated by enzymes to selectively give specific products, while others proceed randomly to produce mixtures of many kinds of regioisomers and stereoisomers. The efficacy of antioxidants against lipid oxidation depends on the nature of the oxid ...